CN102989538A - Clamping device of micro-fluidic chip - Google Patents
Clamping device of micro-fluidic chip Download PDFInfo
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- CN102989538A CN102989538A CN 201210548787 CN201210548787A CN102989538A CN 102989538 A CN102989538 A CN 102989538A CN 201210548787 CN201210548787 CN 201210548787 CN 201210548787 A CN201210548787 A CN 201210548787A CN 102989538 A CN102989538 A CN 102989538A
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Abstract
The invention relates to a clamping device, and particularly relates to a clamping device of a micro-fluidic chip. According to the clamping device of the micro-fluidic chip provided by the invention, bracket guide rails are arranged at the four sides on a base of the clamping device; bracket fixers are placed on the bracket guide rails; the bracket guide rails are hinged with bracket rods through the bracket fixers; a plurality of universal sliding blocks are arranged on the bracket rods; supporting rods pass through the universal sliding blocks; clamping openings are formed in the tail ends of the supporting rods; limiting particles are arranged at the top ends of the bracket rods; fixing bolts are arranged on the bracket fixers; sliding block fixing bolts are arranged on the universal sliding blocks; a pair of buckles is arranged on the chip guide rails; a coupling machine is arranged on a liquid injection opening inside the micro-fluidic chip; and a double-layer sucker is arranged at the tail end of the coupling device. The clamping device provided by the invention solves the adaptability problem of a multi-position interface by using the structural design of a three-dimensional opposite connection and a buckle pressurizing block; an interface sealing problem can be solved by using a manner of the double-layer sucker of the coupling device; and the adaptability on chips with different thicknesses can be ensured by using a spring type buckle structure.
Description
Technical field
The present invention relates to clamping device, particularly relate to a kind of clamping device of micro-fluidic chip.
Background technology
Micro-fluidic chip technology (Microfluidics) is that the basic operation units such as the sample preparation of biological, chemistry, medical analysis process, reaction, separation, detection are integrated on the chip of a micro-meter scale, automatically finishes the analysis overall process.Because it in the great potential in the fields such as biology, chemistry, medical science, has developed into the brand-new research field of the subject crossing such as a biology, chemistry, medical science, fluid, electronics, material, machinery.The international latest development of micro-fluidic chip technical field is introduced in report, in conjunction with for many years micro-fluidic chip research and development of speaker achievement, introduces the complete and unique chip manufacturing process technology of a cover, and the microchip of multiple different application.
When using micro-fluidic chip to carry out the various operation such as biochemical analysis, detection, sample and reagent are injected into the fluid channel from the corresponding liquid injection port of micro-fluidic chip, and when injecting for test sample, operating the generation waste liquid can constantly get rid of from the liquid outlet of chip.Clamping device plays is exactly the effect that connects fluid channel and the common macro-scale devices such as syringe of micro-fluidic chip inside.Development along with the subject such as biological, chemical improves constantly the functional diversities of micro-fluidic chip and the requirement of structure assembly.The complexity of the flow passage structure of micro-fluidic chip is compared with traditional cross electrophoresis chip and is greatly improved at present.The same micro-fluidic chip comprises a plurality of liquid injection port and liquid outlet usually, is distributed in the diverse location of chip, and the phase mutual edge distance is very approaching.This just proposes following requirement to clamping device:
(l) clamping device will have suitable flexibility, is in the micro-fluidic chip of diverse location to adapt to liquid injection port, liquid outlet.
(2) the clamping device structural design is small and exquisite, to adapt to the less micro-fluidic chip of interface spacing.
(3) to have good sealing, in order to avoid reagent goes out to leak from interface.
Summary of the invention
In order to overcome the shortcoming and defect of existing micro-fluidic chip interface mode, the object of the present invention is to provide a kind of microflow control chip clamping device that is applicable to have a plurality of liquid injection port and liquid outlet.
The technical scheme that the present invention solves its technical problem employing is: a kind of clamping device of micro-fluidic chip, its structure mainly comprises: liquid injection port, microfluidic control chip, device pedestal, chip guide rail, support fixator, pull blank pipe, cradling piece in button, support guide, set bolt, universal slide block, slide block set bolt, pole, spacing particle, hookup, double-deck sucker, the hookup
Four limits are provided with support guide on the described device pedestal, are mounted with the support fixator on the support guide, by the support fixator so that support guide and cradling piece be hinged; Cradling piece is provided with a plurality of universal slide blocks, is installed with pole in the universal slide block, and pole one end is provided with bayonet socket, and the cradling piece top is provided with spacing particle; The support fixator is provided with set bolt, and universal slide block is provided with the slide block set bolt; The chip guide rail is provided with a pair of button of pulling;
Liquid injection port in the microfluidic control chip is provided with hookup, and the hookup end is provided with double-deck sucker.
Above-mentioned device base bottom surface is transparent baffle.
The above-mentioned button of pulling is pulled for spring and is buckled.
The beneficial effect that the present invention has is: this device adopts the three-dimensional adaptability problem that the structural design of handing over, pull the button pressurizing block has been solved the multiposition interface; Adopted the mode of the double-deck sucker of hookup to solve the sealing joint problem; Adopt spring to pull buckle structure to guarantee the adaptability to the different-thickness chip.
Description of drawings
Fig. 1 is wherein a kind of micro-fluidic chip planar structure schematic diagram of the present invention.
Fig. 2 is the whole formation of the clamping device schematic diagram of micro-fluidic chip of the present invention.
Fig. 3 is the floor map under many hookup states of clamping device clamping of micro-fluidic chip of the present invention.
Fig. 4 is the schematic diagram of the double-deck sucker of hookup of the clamping device of micro-fluidic chip of the present invention.
1-liquid injection port among the figure, 2-microfluidic control chip, 3-device pedestal, 4-chip guide rail, 5-support fixator, 6-pulls button, the 7-support guide, 8-set bolt, the universal slide block of 9-, 10-slide block set bolt, 11-pole, the spacing particle of 12-, the 13-hookup, the double-deck sucker of 14-, blank pipe in the 15-hookup, 16-cradling piece.
The specific embodiment
1-4 makes a detailed explanation the specific embodiment of the present invention below in conjunction with accompanying drawing.
Embodiment: a kind of clamping device of micro-fluidic chip, its structure mainly comprises: liquid injection port 1, microfluidic control chip 2, device pedestal 3, chip guide rail 4, support fixator 5, pull blank pipe 15, cradling piece 16 in button 6, support guide 7, set bolt 8, universal slide block 9, slide block set bolt 10, pole 11, spacing particle 12, hookup 13, double-deck sucker 14, the hookup
Four limits are provided with support guide 7 on the described device pedestal 3, are mounted with support fixator 5 on the support guide 7, by support fixator 5 so that support guide 7 be hinged with cradling piece 16; Cradling piece 16 is provided with a plurality of universal slide blocks 9, is installed with pole 11 in the universal slide block 9, and pole 11 1 ends are provided with bayonet socket, and cradling piece 16 tops are provided with spacing particle 12; Support fixator 5 is provided with set bolt 8, and universal slide block 9 is provided with slide block set bolt 10; Chip guide rail 4 is provided with a pair of button 6 of pulling;
Described device pedestal 3 bottom surfaces are transparent baffle.
The described button 6 of pulling is pulled for spring and to be buckled.
The below does once detailed step to whole operating process and explains: because microfluidic control chip 2 its liquid injection port 1 have a plurality of, and every kind of different microfluidic control chips 2 its aperture positions all are uncertain, so its support should be flexible and changeable, and its fixed coordinates can be arbitrarily.
Clamping work begins: at first get a microfluidic control chip 2, pull open button 6, it is placed in the device pedestal 3, then will pull button 6 and buckle fixing.Assign the quantity of hookup 13 to assign according to microfluidic control chip 2 actual needs complete, get a ruler and measure coordinate points, set bolt 8 on the support fixator 5 is unscrewed, so that corresponding two cradling pieces 16 can move at support guide 7 according to the coordinate points that ruler is determined, can determine the coordinate of horizontal plane after the movement, tighten the set bolt 8 on the support fixator 5 this moment.
Then, unscrew the slide block set bolt 10 on the cradling piece 16 to slide block 9 can slide up and down along cradling piece 16, pole 11 can all directions pull and push.Because it is a plurality of that possible hookup 13 has, therefore can exist pole 11 when same horizontal plane upper support, two bars occur and intersect situation about crashing, and slide block 9 can slide up and down and created the multilevel layout of clamping, has realized three-dimensional clamping; After level, vertical two direction Coordinates calibrations are complete, tighten slide block set bolt 10, realize the clamping purpose.
The effect of chip guide rail 4 is to adjust the adaptability size of settling microfluidic control chip 2, in order to obtain good fixed effect; Pulling button 6 pulls for spring and to buckle to adapt to various microfluidic control chip 2 various thickness; Spacing particle 12 effects on cradling piece 16 tops are to prevent that universal slide block 9 from skidding off cradling piece 16; Device pedestal 3 bottom surfaces are that transparent baffle its objective is in order to make things convenient for flow direction to observe.
Claims (3)
1. the clamping device of a micro-fluidic chip, its structure mainly comprises: liquid injection port (1), microfluidic control chip (2), device pedestal (3), chip guide rail (4), support fixator (5), pull button (6), support guide (7), set bolt (8), universal slide block (9), slide block set bolt (10), pole (11), spacing particle (12), hookup (13), double-deck sucker (14), the interior blank pipe (15) of hookup, cradling piece (16)
It is characterized in that: device pedestal (3) upper four limits are provided with support guide (7), are mounted with support fixator (5) on the support guide (7), by support fixator (5) so that support guide (7) and cradling piece (16) be hinged; Cradling piece (16) is provided with a plurality of universal slide blocks (9), is installed with pole (11) in the universal slide block (9), and pole (11) one ends are provided with bayonet socket, and cradling piece (16) top is provided with spacing particle (12); Support fixator (5) is provided with set bolt (8), and universal slide block (9) is provided with slide block set bolt (10); Chip guide rail (4) is provided with a pair of button (6) of pulling;
Liquid injection port (1) in the microfluidic control chip (2) is provided with hookup (13), and hookup (13) end is provided with double-deck sucker (14).
2. the clamping device of a kind of micro-fluidic chip according to claim 1 is characterized in that described device pedestal (3) bottom surface is transparent baffle.
3. the clamping device of a kind of micro-fluidic chip according to claim 1 is characterized in that the described button (6) of pulling pulls for spring and buckle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210548787.6A CN102989538B (en) | 2012-12-17 | 2012-12-17 | The clamping device of micro-fluidic chip |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210548787.6A CN102989538B (en) | 2012-12-17 | 2012-12-17 | The clamping device of micro-fluidic chip |
Publications (2)
| Publication Number | Publication Date |
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| CN102989538A true CN102989538A (en) | 2013-03-27 |
| CN102989538B CN102989538B (en) | 2016-08-10 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210548787.6A Active CN102989538B (en) | 2012-12-17 | 2012-12-17 | The clamping device of micro-fluidic chip |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109991195A (en) * | 2019-04-24 | 2019-07-09 | 浙江警察学院 | A kind of SPR detector single channel micro-fluidic chip clamping system |
| CN113019490A (en) * | 2021-03-05 | 2021-06-25 | 苏州工业职业技术学院 | Micro-current control chip fixing clamp capable of being micro-adjusted |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6498497B1 (en) * | 1998-10-14 | 2002-12-24 | Caliper Technologies Corp. | Microfluidic controller and detector system with self-calibration |
| DE102005045811A1 (en) * | 2005-09-27 | 2007-04-05 | Siemens Ag | Microfluidic system comprises a series of modules, each comprising a microfluidic part that is bolted onto a support surface and comprises a fluid channel system with connectors for attachment to adjacent modules |
| DE602006021151D1 (en) * | 2006-05-11 | 2011-05-19 | Corning Inc | Modular holding and connection system for microfluidic devices |
| CN101303327B (en) * | 2008-06-20 | 2012-05-23 | 浙江大学 | Microflow control chip clamping device |
| CN202962493U (en) * | 2012-12-17 | 2013-06-05 | 江西恒盛晶微技术有限公司 | Clamping device for micro-fluidic chip |
-
2012
- 2012-12-17 CN CN201210548787.6A patent/CN102989538B/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109991195A (en) * | 2019-04-24 | 2019-07-09 | 浙江警察学院 | A kind of SPR detector single channel micro-fluidic chip clamping system |
| CN113019490A (en) * | 2021-03-05 | 2021-06-25 | 苏州工业职业技术学院 | Micro-current control chip fixing clamp capable of being micro-adjusted |
| CN113019490B (en) * | 2021-03-05 | 2024-06-07 | 苏州工业职业技术学院 | Micro-control flow chip fixing clamp capable of being adjusted in micro mode |
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| Publication number | Publication date |
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| CN102989538B (en) | 2016-08-10 |
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Effective date of registration: 20200109 Address after: 330000 Nanchang 1, unit 702, Jiangxin District, 24 Jin Ping Road, Xihu District, Nanchang, Jiangxi. Patentee after: Xu Yunpeng Address before: 330096 hi tech building, No. 18, two hi tech Road, Nanchang hi tech Zone, Jiangxi, 512 Patentee before: JIANGXI CRYSTAL BIOSENSOR TECHNOLOGY Co.,Ltd. |
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Effective date of registration: 20201209 Address after: 330000 south of 5th floor, building 15, No. 346, xiaolanzhong Avenue, Xiaolan economic and Technological Development Zone, Nanchang County, Nanchang City, Jiangxi Province Patentee after: Jiangxi Zhonglan Electronic Manufacturing Co.,Ltd. Address before: 330000 Nanchang 1, unit 702, Jiangxin District, 24 Jin Ping Road, Xihu District, Nanchang, Jiangxi. Patentee before: Xu Yunpeng |
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| CB03 | Change of inventor or designer information | ||
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Inventor after: Xu Yunpeng Inventor after: Yan Chunhui Inventor after: Liu Wencao Inventor after: Zhou Yuxing Inventor before: Xu Yunpeng Inventor before: Yan Chunhui |