CN102988498A - Medicine composition for treating leucoderma - Google Patents
Medicine composition for treating leucoderma Download PDFInfo
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- CN102988498A CN102988498A CN201210404986XA CN201210404986A CN102988498A CN 102988498 A CN102988498 A CN 102988498A CN 201210404986X A CN201210404986X A CN 201210404986XA CN 201210404986 A CN201210404986 A CN 201210404986A CN 102988498 A CN102988498 A CN 102988498A
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- parts
- radix
- medicine composition
- vitiligo
- semen sesami
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- 239000003814 drug Substances 0.000 title abstract description 11
- 229940079593 drug Drugs 0.000 title abstract description 3
- 210000000582 semen Anatomy 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 241000756943 Codonopsis Species 0.000 claims description 10
- 241000628997 Flos Species 0.000 claims description 10
- 241000237903 Hirudo Species 0.000 claims description 10
- 241000972155 Moschus Species 0.000 claims description 10
- 239000008194 pharmaceutical composition Substances 0.000 claims description 9
- 239000000463 material Substances 0.000 claims description 4
- 238000002360 preparation method Methods 0.000 abstract description 11
- 241000213006 Angelica dahurica Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 241000007126 Codonopsis pilosula Species 0.000 abstract 1
- 241000402754 Erythranthe moschata Species 0.000 abstract 1
- 241001289529 Fallopia multiflora Species 0.000 abstract 1
- 241000545744 Hirudinea Species 0.000 abstract 1
- 235000007215 black sesame Nutrition 0.000 abstract 1
- 206010047642 Vitiligo Diseases 0.000 description 17
- 210000003491 skin Anatomy 0.000 description 6
- 230000035614 depigmentation Effects 0.000 description 5
- 208000017520 skin disease Diseases 0.000 description 5
- 206010025421 Macule Diseases 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 238000012216 screening Methods 0.000 description 4
- 230000003796 beauty Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 239000000049 pigment Substances 0.000 description 3
- 206010040882 skin lesion Diseases 0.000 description 3
- 231100000444 skin lesion Toxicity 0.000 description 3
- 230000000472 traumatic effect Effects 0.000 description 3
- 206010010356 Congenital anomaly Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010048768 Dermatosis Diseases 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 210000003780 hair follicle Anatomy 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000002752 melanocyte Anatomy 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- ZCCUUQDIBDJBTK-UHFFFAOYSA-N psoralen Chemical compound C1=C2OC(=O)C=CC2=CC2=C1OC=C2 ZCCUUQDIBDJBTK-UHFFFAOYSA-N 0.000 description 2
- VXGRJERITKFWPL-UHFFFAOYSA-N 4',5'-Dihydropsoralen Natural products C1=C2OC(=O)C=CC2=CC2=C1OCC2 VXGRJERITKFWPL-UHFFFAOYSA-N 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 206010011878 Deafness Diseases 0.000 description 1
- 208000031361 Hiccup Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 206010047513 Vision blurred Diseases 0.000 description 1
- 239000003470 adrenal cortex hormone Substances 0.000 description 1
- 231100000360 alopecia Toxicity 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 210000004209 hair Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000023513 hiccough Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 210000003141 lower extremity Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 239000000712 neurohormone Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000007493 shaping process Methods 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Abstract
The invention belongs to an oral Chinese medicine preparation in the field of medicines, and in particular relates to a medicine composition for treating leucoderma. The medicine composition is prepared from the following raw materials in parts by weight: 10-30 parts of Chinese angelica, 10-20 parts of codonopsis pilosula, 10-20 parts of safflower, 10-15 parts of leech, 10-15 parts of fig, 10-15 parts of black sesame semen sesami nigrum, 10-15 parts of polygonum multiflorum and 5-10 parts of musk. The medicine composition is good in stability without recurring.
Description
Technical field
The invention belongs to the oral medicinal herb preparation of field of medicaments, be specifically related to a kind of leukodermic pharmaceutical composition for the treatment of.
Background technology
Vitiligo is a kind of common multiple pigmented dermatosis.This disease forms white macula as feature take local or general property depigmentation, is a kind of acquired limitation or general property depigmentation of skin, is the common skin diseases of an impact beauty treatment, easily diagnosis, and treatment is difficult.Traditional Chinese medical science medical science is referred to as " vitiligo " or " vitiligo ".Vitiligo is that posteriority is lost the limitation white patch that occurs because skin pigment takes off, so that local skin is the white macula sample.Medically usually this pathological changes depigmentation.
This disease all has generation all over the world, and India's sickness rate is the highest, and China has ten million people morbidity approximately, can involve all races, and the men and women falls ill without marked difference.Vitiligo is divided into congenital vitiligo: congenital vitiligo is a kind of constitutional, limitation or general property depigmentation of skin, is that hypofunction, the forfeiture of tryrosinase system in the melanocyte owing to skin and hair follicle causes.Skin lesion for have not a particle of pigment, differ in size, different, white macula all can occur everywhere in whole body, clear border, the border pigment is darker, hair follicle bleaches in the speckle.
Traumatic vitiligo: traumatic vitiligo is one acquired, general property depigmentation of skin, is a kind of common skin diseases that affects beauty treatment.Easily diagnose and the treatment difficulty.Motherland's medical science is referred to as " leucoderma " or " vitiligo ".By wound, the vitiligo of bringing out such as perform the operation, scratch is called traumatic vitiligo.
The segmental vitiligo: the segmental vitiligo is a kind of incontinentia pigmentosa achromians dermatoses of limitation.The teenager morbidity is more.Skin lesion is clearly white macula of boundary, circle, oval or not shaping.Can betide any position of health.No conscious sympton does not affect healthyly, but impact beauty treatment can bring spiritual misery to patient.Minority small pieces skin lesion can disappear voluntarily, and Nervous and Mental Factors, Exposure to Sunlight, wound can make sx↑ or bring out primary disease.Etiology unknown has theory of autoimmunity, neuro humor theory, melanocyte autoclasia theory etc.The extensive person of disease damage can try out photochemotherapy, and namely oral psoralen adds the long wave ultraviolet radiation.Local available various corticosteroid hormone preparations
Although vitiligo is a kind of dermatosis, no matter be western medicine, or Chinese medicine, think that all leukodermic pathogeny is in the body, the treatment to appearance of pure is difficult to reach the purpose of healing.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of leukodermic pharmaceutical composition for the treatment of of good stability.
Content of the present invention is, made by the material component of following parts by weight,
Radix Angelicae Sinensis 10-30 part, Radix Codonopsis 10-20 part, Flos Carthami 10-20 part, Hirudo 10-15 part, Fructus Fici 10-15 part, Semen Sesami Nigrum 10-15 part, Radix Polygoni Multiflori 10-15 part, Moschus 5-10 part.
Preferably, made by the raw material of following parts by weight,
Radix Angelicae Sinensis 20-30 part, Radix Codonopsis 15-20 part, Flos Carthami 15-20 part, Hirudo 13-15 part, Fructus Fici 13-15 part, Semen Sesami Nigrum 13-15 part, Radix Polygoni Multiflori 13-15 part, Moschus 5-8 part.
Most preferred, it is characterized in that, made by the raw material of following parts by weight,
30 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 20 parts on Flos Carthami, 13 parts of Hirudos, 13 parts of Fructus Ficis, 13 parts of Semen Sesami Nigrums, 13 parts of Radix Polygoni Multiflori, 5 parts in Moschus.
Preparation method of the present invention is that above-mentioned component is mixed, and then crushing screening makes corresponding dosage form according to the dosage form preparation method of separately Chinese medicine.
Instructions of taking of the present invention is, and is oral, every day 2-3 time, and a 5-10g, the morning, noon and afternoon rush after meal warm water and take.
The invention has the beneficial effects as follows that the function that each component of the present invention has separately is: Radix Angelicae Sinensis: enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation; Radix Codonopsis, invigorating the spleen and replenishing QI and taste, relieving thirst and restlessness.A little less than the middle feeble QI, mend in order to transfer, very smooth and proper; Flos Carthami is invigorated blood circulation, moisturizes, and pain relieving, loose swollen, stimulate the menstrual flow; Hirudo: removing blood stasis, by becoming silted up; Fructus Fici, invigorating the stomach and promoting bowel movement, subduing swelling and detoxicating; Semen Sesami Nigrum: invigorating the liver and kidney, benefiting essence-blood, intestine moistening is dry.Be used for dizziness and blurred vision, Hiccough and deaf, early whitening of beard and hair, post disease alopecia, dryness of the intestine constipation; Radix Polygoni Multiflori: enter the Gallbladder Channel of Foot-Shaoyang, triple energizer meridian, heart channel of Hand-Shaoyin, kidney meridian; Moschus: the refreshment of having one's ideas straightened out, promoting blood circulation to restore menstrual flow, pain relieving is hastened parturition.
The specific embodiment
Embodiment 1
The present invention is made than component by following weight fraction, 30 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 20 parts on Flos Carthami, 13 parts of Hirudos, 13 parts of Fructus Ficis, 13 parts of Semen Sesami Nigrums, 13 parts of Radix Polygoni Multiflori, 5 parts in Moschus.
Preparation method of the present invention is above-mentioned component to be mixed crushing screening.
Embodiment 2
The present invention is made by the material component of following parts by weight,
30 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 20 parts on Flos Carthami, 10 parts of Hirudos, 10 parts of Fructus Ficis, 15 parts of Semen Sesami Nigrums, 10 parts of Radix Polygoni Multiflori, 5 parts in Moschus.
Preparation method of the present invention is above-mentioned component to be mixed crushing screening.
Embodiment 3
The present invention is made by the material component of following parts by weight,
10 parts of Radix Angelicae Sinensis, 10 parts of Radix Codonopsis, 10 parts on Flos Carthami, 15 parts of Hirudos, 15 parts of Fructus Ficis, 10 parts of Semen Sesami Nigrums, 15 parts of Radix Polygoni Multiflori, 10 parts in Moschus.
Preparation method of the present invention is above-mentioned component to be mixed crushing screening.
Medicine of the present invention prepares vitiligo 201 examples, and effective percentage reaches 98.5%.
Pharmaceutical composition with embodiment 1 preparation is taken, and below is several model cases.
Liu, the woman, 33 years old, people from Wuhan, Hubei suffered from vitiligo 3 places, back, about 30cm
2, ill 4 years, behind the pharmaceutical composition of use embodiment 1 preparation, recovery from illness after 6 months, nothing recurrence after the recovery from illness.
Lee.The man, 45 years old, people from Gongan County, Hubei, the large tracts of land such as arm, lower limb are ill, ill 10 years, permanent treatment, poor effect, take the pharmaceutical composition of embodiment 1 preparation after, recovery from illness after 9 months, after the recovery from illness without recurrence.
Claims (3)
1. the leukodermic pharmaceutical composition for the treatment of is characterized in that, made by the material component of following parts by weight,
Radix Angelicae Sinensis 10-30 part, Radix Codonopsis 10-20 part, Flos Carthami 10-20 part, Hirudo 10-15 part, Fructus Fici 10-15 part, Semen Sesami Nigrum 10-15 part, Radix Polygoni Multiflori 10-15 part, Moschus 5-10 part.
2. the leukodermic pharmaceutical composition for the treatment of according to claim 1 is characterized in that, made by the raw material of following parts by weight,
Radix Angelicae Sinensis 20-30 part, Radix Codonopsis 15-20 part, Flos Carthami 15-20 part, Hirudo 13-15 part, Fructus Fici 13-15 part, Semen Sesami Nigrum 13-15 part, Radix Polygoni Multiflori 13-15 part, Moschus 5-8 part.
3. the leukodermic pharmaceutical composition for the treatment of according to claim 1 and 2 is characterized in that, made by the raw material of following parts by weight,
30 parts of Radix Angelicae Sinensis, 20 parts of Radix Codonopsis, 20 parts on Flos Carthami, 13 parts of Hirudos, 13 parts of Fructus Ficis, 13 parts of Semen Sesami Nigrums, 13 parts of Radix Polygoni Multiflori, 5 parts in Moschus.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210404986.XA CN102988498B (en) | 2012-10-13 | 2012-10-13 | Medicine composition for treating leucoderma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210404986.XA CN102988498B (en) | 2012-10-13 | 2012-10-13 | Medicine composition for treating leucoderma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102988498A true CN102988498A (en) | 2013-03-27 |
| CN102988498B CN102988498B (en) | 2014-11-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210404986.XA Expired - Fee Related CN102988498B (en) | 2012-10-13 | 2012-10-13 | Medicine composition for treating leucoderma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102988498B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115006431A (en) * | 2022-08-09 | 2022-09-06 | 云南三江本草药业有限公司 | Application of poecilobdella manillensis in preparing medicine for treating leucoderma and medicinal preparation |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175436A (en) * | 1997-06-20 | 1998-03-11 | 苏新发 | Chinese patent drug for treatment of leukoderma |
| CN1177489A (en) * | 1997-09-02 | 1998-04-01 | 史培明 | Chines medicine for treating vitiligo and preparation method thereof |
| US20010044422A1 (en) * | 1999-12-29 | 2001-11-22 | Huiping Zhao | Composition and method for the treatment of vitiligo |
| US20030072813A1 (en) * | 1999-12-29 | 2003-04-17 | Huiping Zhao | Composition and method for the treatment of vitiligo |
| CN101461847A (en) * | 2009-01-13 | 2009-06-24 | 牛付立 | Medicament composition for treating leukoderma |
| KR20100029341A (en) * | 2008-09-08 | 2010-03-17 | (주)한중보건연구원 | Skin (white spot) rejuvenation ointment |
| CN102441067A (en) * | 2010-09-30 | 2012-05-09 | 张赞 | Preparation method of medicine for treating leucoderma |
-
2012
- 2012-10-13 CN CN201210404986.XA patent/CN102988498B/en not_active Expired - Fee Related
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1175436A (en) * | 1997-06-20 | 1998-03-11 | 苏新发 | Chinese patent drug for treatment of leukoderma |
| CN1177489A (en) * | 1997-09-02 | 1998-04-01 | 史培明 | Chines medicine for treating vitiligo and preparation method thereof |
| US20010044422A1 (en) * | 1999-12-29 | 2001-11-22 | Huiping Zhao | Composition and method for the treatment of vitiligo |
| US20030072813A1 (en) * | 1999-12-29 | 2003-04-17 | Huiping Zhao | Composition and method for the treatment of vitiligo |
| KR20100029341A (en) * | 2008-09-08 | 2010-03-17 | (주)한중보건연구원 | Skin (white spot) rejuvenation ointment |
| CN101461847A (en) * | 2009-01-13 | 2009-06-24 | 牛付立 | Medicament composition for treating leukoderma |
| CN102441067A (en) * | 2010-09-30 | 2012-05-09 | 张赞 | Preparation method of medicine for treating leucoderma |
Non-Patent Citations (1)
| Title |
|---|
| 宋业强等: "9个中药复方水提取物对蘑菇酪氨酸酶活性的影响", 《中医临床研究》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115006431A (en) * | 2022-08-09 | 2022-09-06 | 云南三江本草药业有限公司 | Application of poecilobdella manillensis in preparing medicine for treating leucoderma and medicinal preparation |
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| Publication number | Publication date |
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| CN102988498B (en) | 2014-11-26 |
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