CN101176758B - Medicine for treating leucoderma and its preparation method - Google Patents
Medicine for treating leucoderma and its preparation method Download PDFInfo
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Abstract
The invention relates to a Chinese patent drug for vitligo and a preparation method thereof. The preparation material comprises the technical products of the fresh phoenix tree leaf 800 to less than 1200 portion, the radix-polygoni multiflori 0 to 400 portion, the fructus psoraleae 0 to 300 portion, the white caltrop 0 to 200 portion; the open-eyed preparation method is that, taking the phoenix tree leaf and other material pro rata, mixing, adding water to quench, steam boiling, the remaining juice after removing the slag can be directly used as medicine, and also can be boiled out into the ointment, adding the filler, to make oral medicine. The invention has the advantages of, (1) no pungency, no toxicity, overcoming the pain and the adverse reactions caused by the injection and the skin-grafting illumination, convenient medications, obvious therapeutic effect, high cure rate; (2) being easy to get for the raw material, easy working procedure, low investment, relatively low medical service, being accepted by sufferers.
Description
(1) technical field
The present invention relates to dermopathic medicine of a kind of treatment and preparation method thereof, particularly relate to leukodermic Chinese patent medicine of treatment and preparation method thereof.
(2) background technology
Vitiligo is the difficult dermatosis due to the factors such as common a kind of posteriority hypopigmentation of department of dermatologry or pigment obstacle, have a very wide distribution, and sickness rate has the trend of rising in recent years.At present leukodermic method of treatment and medicine are a lot, but most curative effect can not be satisfactory, and treat with high costsly, and general patient is difficult to afford.Like Therapeutic Method such as " laser ", " skin-grafting ", " freezing ", not only treat with high costsly, also can on skin, stay cicatrix, curative effect is also not fully up to expectations; Multiple therapy of vitiligo medicine, as the speckle removing ball, go Bai Su etc. in process of clinical application, exist the course of treatment long, cure rate is low, the shortcoming of toxic side effect; ZL98101552.2 discloses a kind of externally-applied medicinal composition of treating leucoderma disease; Be considered to certain therapeutic effect; But its required crude drug kind is more; Also have some raw materials to be difficult for obtaining (like Cornu Saigae Tataricae fine powder, Radix Salviae Miltiorrhizae etc.), cause the implementation cost of this scheme high, general patient is difficult to afford.
(3) summary of the invention
The technical problem that the present invention will solve provides a kind of good effect, has no side effect and the leukodermic medicine of the cheap treatment that is easy to get of raw material, and provides the simple method for preparing of this medicine.
For solving the problems of the technologies described above, the technical scheme that the present invention adopts is:
The leukodermic medicine of a kind of treatment is characterized in that, in weight portion, its preparation contains the bright blue or green Folium paulowniae 800 of former medicine～＜1200 parts, 0～400 part of Radix Polygoni Multiflori, 0～300 part of Fructus Psoraleae, 0～200 part of Fructus Atriplicis Sibiricae in raw material.
Contain the bright blue or green Folium paulowniae 800 of the former medicine of former medicine～＜1200 parts, 0～400 part of Radix Polygoni Multiflori, 100～300 parts of Fructus Psoraleaes, 0～200 part of Fructus Atriplicis Sibiricae in the preparation raw material of the leukodermic medicine of described treatment.
Contain the bright blue or green Folium paulowniae 800 of former medicine～＜1200 parts, 200～400 parts of the Radixs Polygoni Multiflori, 0～300 part of Fructus Psoraleae, 0～200 part of Fructus Atriplicis Sibiricae in the preparation raw material of the leukodermic medicine of described treatment.
Contain the bright blue or green Folium paulowniae 800 of former medicine～＜1200 parts, 200～400 parts of Radix Polygoni Multiflori, 0～300 part of Fructus Psoraleae, 100～200 parts of Fructus Atriplicis Sibiricaees in the preparation raw material of the leukodermic medicine of described treatment.
Contain the bright blue or green Folium paulowniae 800 of former medicine～＜1200 parts, 0～400 part of the Radix Polygoni Multiflori, 100～300 parts of Fructus Psoraleaes, 100～200 parts of Fructus Atriplicis Sibiricaees in the preparation raw material of the leukodermic medicine of described treatment.
Contain 900～1100 parts of the bright blue or green Folium paulowniae of former medicine in the preparation raw material of the leukodermic medicine of described treatment, 200～400 parts of Radix Polygoni Multiflori, 100～300 parts of Fructus Psoraleaes, 100～200 parts of Fructus Atriplicis Sibiricaees.
A kind of method for preparing of treating leukodermic medicine may further comprise the steps:
(1) gets bright blue or green Folium paulowniae 1000 weight portions and clean and to dry, and take by weighing all the other each raw materials;
(2) water-cooled that adds 6000～9000 weight portions after each raw materials mix was soaked 2～4 hours, boiled 0.5～2 hour again;
(3) will go up step gained juice and be filtered in the container, after in filtering residue, adding water 0.5～2 weight portion continued and boiling, filter and remove residue gained juice and the merging of aforementioned juice.
Be sub-packed in 30～50ml bottle after gained juice in the above-mentioned steps (3) put cold, pack after the sterilization and be exterior-applied formulation.
With gained juice decocting and concentrating in the above-mentioned steps (3) to the runny plaste shape; Put cool back and add ethanol 200～400 weight portions, left standstill 2～4 hours after slowly stirring, again with its simmer down to thick paste shape; Put the medical filler that cool back adds 0.5～1.0 weight portion, process peroral dosage form.
Above-mentioned medical filler is a medical starch, and said peroral dosage form is a graininess, every heavy 1～2g.
The usage of medicine of the present invention and consumption:
1. oral administration pills or capsule are example with granule (every heavy 1.2g) shape, every day 2 times, each 1; 1 month is a course of treatment, takes continuously 3 months, treat that white macula disappears or skin recover basically normal after; Change into every day 1 time or the next day 1 time, each 1, serve on 3 months to consolidate curative effect;
2. exterior-applied formulation is directly smeared the affected part, and every day 1～2 time, consumption is looked the size of skin lesion and decided, and administration time recovers till the normal color of the leather with skin lesion.
The present invention has actively useful effect:
(1) compare with domestication student Tetramune and X-ray therapy with this Drug therapy vitiligo and have following characteristics: 1. non-stimulated, have no side effect, overcome caused pain and untoward reaction such as injection, skin-grafting illumination; 2. the raw material medicine is easy to obtain, operation is easy, small investment, medical expense are cheap relatively, and the patient can accept.
(2) scientific formulation is reasonable, and each medicine is in step with, and cooperatively interacts, and synergism, therapeutic effect are more remarkable.
Pharmacology analysis of the present invention:
Works such as motherland's medical science " all cause of disease wait opinion ", Golden Mirror of Medicine, " Standards of Diagnosis and Treatment " are discussed vitiligo is existing, and summary is thought the skin QI and blood deficiency, and the qi-blood disharmony damp-stagnancy that becomes a common practice is due to the fur.In recent years; Fast development along with the modern medicine technology; For probing into the leukodermic cause of disease, scientists is constantly carried out deep research from physiology, biology, biochemistry, heredity, immune molecule and cell division and the aspects such as cycle variation and trace element of human body skin, finds that tryrosinase is the synthetic key enzyme of melanin; Be considered to the autoimmune important antigen of vitiligo; And the pathology reason that causes skin pigment to take off mistake is that the tryrosinase of human body is suppressed, and causes functional melanocyte to be subjected to destroy to some extent, and then causes the melanin metabolic process to be obstructed.
But Firmiana platanifolia (Linn. f.) Marsili point-score paulownia, blue or green paulownia, Paulownia, Folium et Ramulus Clerodendri Trichotomi etc., blue or green Folium paulowniae according to the invention is from blue or green tung oil tree, and is very extensive in the growth region of China.Blue or green Folium paulowniae, property is put down bitter in the mouth, and is little nontoxic; Return lung meridian; Contain compositions such as flavonoid glycoside, meso inositol (Myoinosito), natural pigment and other bitter in the mouth element, this type material gets into can play rapidly behind the Cytoplasm regulates cells physiological, biochemical action, activates tryrosinase; Impel melanocyte to recover normal physiological function, thereby reach the leukodermic purpose of treatment.
Radix Polygoni Multiflori, slightly warm in nature, bitter in the mouth, sweet, puckery; Return liver, the heart, kidney channel, its tuber contains anthraquinone derivatives emodin, chrysophanol, chrysophanic acid and lecithin etc., can promote the newborn and growth of cell; The nutrition brains promote enterokinesia, the effect of tool invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening.
Fructus Atriplicis Sibiricae, warm in nature, bitter in the mouth, suffering; Contain multiple alkaloid, glycoside, fatty oil, volatile oil and multiple abundant peroxide breakdown enzyme etc., have the effect that vessel softening, enhancing microcirculation etc. are invigorated blood circulation, obvious anti-aging effects is arranged; Materials for improving vision is made light of one's life by commiting suicide, cicatrix on the removal face, treatment vitiligo.Compendium of Material Medica is said: " it is black to wash one's face, and speckle dispelling is washed the scar skin ulcer.”
Fructus Psoraleae, another name Fructus Psoraleae, Fructus Psoraleae, black paper recklessly, warm in nature, acrid in the mouth, hardship.Contain flavone compound, Coryfolin, Coumarins chemical compound, Radix Angelicae Dahuricae element, Bakuchiol and volatilization wet goods.Pharmacology: ability is coronary artery dilator obviously; Promote the granulocyte growth; Promote the metabolism of dermal melanin, the expansion local vascular improves histotrophic nutrition.The effect of tool kidney invigorating and YANG supporting, helping inspiration to relieve asthma, warm spleen antidiarrheal.
The Radix Angelicae Dahuricae has another name called Radix Angelicae Dahuricae (Radix Heraclei Scabridi), and acrid in the mouth is warm in nature, returns lung, spleen, stomach, large intestine channel.Function: expelling pathogenic wind from the body surface, dispersing cold for relieving pain, sensible, the detumescence and apocenosis of dehumidifying.Modern pharmacological research proves, the effects such as Fructus Psoraleae is analgesic except that having, analgesia, antiinflammatory, can also improve local blood circulation, eliminates pigment in tissue, excessively to pile up, and promotes skin cell metabolism.The Compendium of Material Medica meaning Radix Angelicae Dahuricae " longue skin, moist color can be made face fat ".
Medicine-feeding is in step with, and shows its effect fully, and Fang Jian is imitated grand.
In recent years, almost all there is every day more than 20 a Bai Dianfeng patient from various parts of the country come the inventor to locate to seek medical advice, patient more than 90% arranged, sought medical advice out of admiration for a famous person because of not good at local therapeutic effect.Belong to outpatient service registration according to the inventor and show that from March 10,2006 10 days to 2007 March in, the prescription on individual diagnosis number reaches 8006 person-times, wherein register full and accurate and totally 630 person-times of therapeutic outcome are arranged, the actual patient of seeking medical advice reaches 5008 people.In the middle of these patients with vitiligo of seeking medical advice, after Drug therapy according to the invention, the healing number is 2100 people, accounts for 42%; 1800 people of produce effects account for 36%; Effective 860 people account for 17%; 248 invalid people account for 5%.
The recovery from illness of therapeutic evaluation standard: white macula all disappears, and recovers the normal colour of skin; Produce effects: white macula partly disappears or dwindles, and the area that recovers the normal colour of skin accounts for skin lesion area 75%; Effectively: white macula partly disappears or dwindles, and the area that recovers the normal colour of skin accounts for skin lesion area 10～50%; Invalid: white macula no change or dwindle, the area that recovers the normal colour of skin accounts for skin lesion area＜10%.
Example 1, Wang Lianpeng, the man, 32 years old, Kaifeng park passerby suffered from vitiligo 9 years, and was initial at hands and face, after develop into upper limb and trunk, lower limb also have several, use up all savings in several years, fail to cure, and can't marry and settle down because of suffering from this disease.Bai Dianfeng out of admiration for a famous person sought medical advice to the inventor place at the beginning of calendar year 2001.Use Drug therapy of the present invention after 3 months, white macula is expansion more, tangible pigmentation speckle is arranged between wherein, increases in flakes gradually, and normal color of the leather is recovered in the back.Former 60% skin (mainly being face and upper limb, breast, the back of the body, abdominal part) the skin lesion face that accounts for reverts to about 10%.After again with this medicine treatment treatment 6 months, be almost recovered, cause has been started in recurrence so far after the drug withdrawal, and take a wife and give birth to son.This patient medication nine months altogether, medical care expenses is about totally 700 yuan.
Example 2, Huang Lihua, the woman, the attending doctor, Bai Dianfeng was suffered from 12 years in No. six building, Rui'an City Ni Cheng road, Zhejiang Province, and skin lesion has accounted for 75% of whole skin, almost abandoning cure.Seek medical advice in come out of admiration for a famous person in May, 2000 inventor place.She was facial at that time, cervical region and upper limb exposure portion skin lesion have accounted for 90% of this position, and hospitalization is after 10 days, and former skin lesion begins ruddy, has occurred the pigment point at the pore place, after be with the treatment of going back of trimestral medicine, medicinal intact after, skin lesion has recovered 50%.After again with after this medicine treatment half a year, the exposure portion skin lesion has recovered 80%.After after treatment 3 months again, the former skin lesion that accounts for whole skin 75% is cured, only has several also to recover normal fully, accounts for about 3% of whole skin.Only more than 1,000 yuan of the expenses for medicine in 1 year.
Example 3, Jiang, people from Shijiazhuang City, Hebei Province; Suffered from vitiligo 3 years, PD is very fast, and the skin lesion face has accounted for about 50% of whole skin; Introduce the inventor to locate to seek medical advice through friend; Through treating six months with this medicine, skin lesion recovers normally fully, and only upper lip left side mucosa and skin junction do not return to normal color of the leather.More not recurrence after.
Example 4, Yuan, the middle schoolgirl, Chinese bush cherry people from villages and small towns, Xincai County, Henan Province, abdominal part to abdominal part ditch finds that white macula is surplus January, does not tell the head of a family, the adularescent pubes are found in the back, the about two palms size of skin lesion face, it is female just leads daughter to come the inventor to punish treatment.Accepted this Drug therapy two months, and fully recovered, take bimestrial medicine after treatment again, thoroughly cure, so far not recurrence in 3 years.
Example 5, Zheng, man, Sun Zhao township, Xincai County, Henan Province cadre; Left side cervical region to back side of head skin and hair turns white, and develops into the palm size in three months, once uses multi-treatment; Though the state of an illness is controlled to some extent, skin lesion does not have obvious change, and the back is with the treatment of this medicine; Be clearly better after one month, it is normal that former after two months skin lesion recovers, not recurrence in 3 years so far.
Example 6, Mrs Zhao, the welcome center staff of the Hunan Province People's Government, it is surplus to suffer from Bai Dianfeng 3 years; Seek medical advice and do not heal in many places, the state of an illness has the expansion tendency, and skin lesion has accounted for 40% of whole skin; Damaging part mainly is back and lower limb, introduces through friend, and special trip comes the inventor to punish treatment; With after this medicine treatment half a year, the basic healing, after again remittance purchase three courses of treatment medicine to consolidate curative effect.
(4) specific embodiment
Embodiment 1: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Fructus Atriplicis Sibiricae 200g.
A kind of method for preparing of treating leukodermic medicine, its step is following: 1. get and clean the blue or green Folium paulowniae 1000g of air dried aquatic foods, take by weighing Fructus Atriplicis Sibiricae 200g simultaneously, and mix with bright Folium paulowniae; 2. in above-mentioned compound, add water 8000g, merceration boiled after 3 hours 1 hour; 3. juice is filtered in the container, after in filtering residue, adding water 1000g again and continuing to boil, filter and remove residue gained juice and aforementioned juice merge; 4. with above-mentioned juice decocting and concentrating to the runny plaste shape, put cool back and add 75% ethanol 300ml, left standstill 3 hours after slowly stirring; 5. the runny plaste shape juice simmer down to thick paste shape after will leaving standstill is again put the medical starch that cool back adds 1000g, the granule of processing, and every heavy 1.2g incapsulates after the drying, and this is a peroral dosage form.
With above-mentioned steps 3. in gained juice be sub-packed in the 50ml bottle after putting cold, pack after the sterilization and be exterior-applied formulation.
Embodiment 2: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1195g, Fructus Atriplicis Sibiricae 200g, Fructus Psoraleae 300g.
A kind of method for preparing of treating leukodermic medicine, its step is following: 1. get and clean the blue or green Folium paulowniae 1200g of air dried aquatic foods, take by weighing Fructus Atriplicis Sibiricae 200g, Fructus Psoraleae 300g simultaneously, and mix with bright Folium paulowniae; 2. in above-mentioned compound, add water 7000g, merceration boiled after 2 hours 2 hours; 3. juice is filtered in the container, in filtering residue, adds water 1000g again and continue to boil, merge with aforementioned juice behind the filter and remove residue; 4. with above-mentioned juice decocting and concentrating to the runny plaste shape, put cool back and add 95% ethanol 250ml, left standstill 2 hours after slowly stirring; 5. the runny plaste shape juice simmer down to thick paste shape after will leaving standstill is again put the medical starch that cool back adds 500g, the granule of processing, and every heavy 1g incapsulates after the drying.
With above-mentioned steps 3. in gained juice be sub-packed in the 30ml bottle after putting cold, pack after the sterilization and be exterior-applied formulation.
Embodiment 3: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Atriplicis Sibiricae 100g, Fructus Psoraleae 200g, Radix Polygoni Multiflori 200g.
A kind of method for preparing of treating leukodermic medicine, its step is following: 1. get and clean the blue or green Folium paulowniae 1100g of air dried aquatic foods, take by weighing Fructus Atriplicis Sibiricae 100g, Fructus Psoraleae 200g, Radix Polygoni Multiflori 200g simultaneously, and mix with bright Folium paulowniae; 2. in above-mentioned compound, add water 9000g, merceration boiled after 4 hours 0.5 hour; 3. juice is filtered in the container, in blue or green Folium paulowniae, adds water 500g continued again and boil, merge with aforementioned juice behind the filter and remove residue; 4. with above-mentioned juice decocting and concentrating to the runny plaste shape, put cool back and add 75% ethanol 400ml, left standstill 1 hour after slowly stirring; 5. the runny plaste shape juice simmer down to thick paste shape after will leaving standstill is again put the medical starch that cool back adds 1000g, the granule of processing, and every heavy 1.3g incapsulates after the drying.
With above-mentioned steps 3. in gained juice be sub-packed in the 40ml bottle after putting cold, pack after the sterilization and be exterior-applied formulation.
Embodiment 4: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Fructus Atriplicis Sibiricae 200g, Fructus Psoraleae 300g, Radix Polygoni Multiflori 300g, vitamin C 300g, levamisole 7500mg.
Basically with embodiment 1, difference is its preparation method: vitamin C and levamisole can directly be added in the cream that is boiled at last, and get final product after stirring.
Embodiment 5: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 900g, vitamin C 300g, levamisole 7500mg.
Basically with embodiment 1, difference is its preparation method: vitamin C and levamisole directly are added in the cream that is boiled into, and stir.
Embodiment 6: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g.
Its preparation method is with embodiment 1.
Embodiment 7: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Psoraleae 300g, Radix Polygoni Multiflori 300g, vitamin C 300g, levamisole 7500mg.
Basically with embodiment 1, difference is its preparation method: vitamin C and levamisole directly are added in the cream that is boiled into, and stir.
Embodiment 8: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Fructus Atriplicis Sibiricae 200g, Radix Polygoni Multiflori 300g, levamisole 7500mg, water 9000g.
Basically with embodiment 1, difference is its preparation method: levamisole directly is added in the cream that is boiled into, and stirs.
Embodiment 9: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1190g, Fructus Atriplicis Sibiricae 50g, Fructus Psoraleae 100g, Radix Polygoni Multiflori 200g.
Its preparation method is with embodiment 1.
Embodiment 10: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 850g, Fructus Atriplicis Sibiricae 300g, Fructus Psoraleae 300g, Radix Polygoni Multiflori 400g.
Its preparation method is with embodiment 1.
Embodiment 11: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 950g, Fructus Atriplicis Sibiricae 150g, Fructus Psoraleae 100g, Radix Polygoni Multiflori 100g.
Its preparation method is with embodiment 1.
Embodiment 12: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Atriplicis Sibiricae 100g, Fructus Psoraleae 300g, Radix Polygoni Multiflori 300g, Radix Angelicae Dahuricae 300g.
Its preparation method is with embodiment 1.
Embodiment 13: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Radix Polygoni Multiflori 300g.
Its preparation method is with embodiment 1.
Embodiment 14: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Psoraleae 300g.
Its preparation method is with embodiment 1.
Embodiment 15: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1150g, Fructus Atriplicis Sibiricae 150g.
Its preparation method is with embodiment 1.
Embodiment 16: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 880g, Fructus Atriplicis Sibiricae 50g, Fructus Psoraleae 200g, Radix Polygoni Multiflori 350g.
Its preparation method is with embodiment 1.
Embodiment 17: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 950g, Fructus Atriplicis Sibiricae 150g, Fructus Psoraleae 300g.
Its preparation method is with embodiment 1.
Embodiment 18: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1050g, Fructus Psoraleae 50g, Radix Polygoni Multiflori 50g.
Its preparation method is with embodiment 1.
Embodiment 19: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1150g, Fructus Atriplicis Sibiricae 180g, vitamin C 100g.
Basically with embodiment 1, difference is its preparation method: vitamin C can directly be added in the cream that is boiled into, and stirs.
Embodiment 20: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 820g, Fructus Psoraleae 380g, Radix Polygoni Multiflori 350g, Radix Angelicae Dahuricae 100g, levamisole 6500mg.
Basically with embodiment 1, difference is its preparation method: levamisole directly is added in the cream that is boiled into, and stirs.
Embodiment 21: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1190g, Fructus Atriplicis Sibiricae 80g, Fructus Psoraleae 150g, Radix Polygoni Multiflori 60g.
Its preparation method is with embodiment 1.
Embodiment 22: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Atriplicis Sibiricae 100g, Fructus Psoraleae 250g, Radix Polygoni Multiflori 400g.
Its preparation method is with embodiment 1.
Embodiment 23: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Fructus Psoraleae 280g, Radix Polygoni Multiflori 260g, Fructus Atriplicis Sibiricae 200g, Radix Angelicae Dahuricae 300g.
Its preparation method is with embodiment 1.
Embodiment 24: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Fructus Psoraleae 180g, Radix Angelicae Dahuricae 300g.
Its preparation method is with embodiment 1.
Embodiment 25: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 900g, Fructus Atriplicis Sibiricae 200g, Radix Angelicae Dahuricae 280g.
Its preparation method is with embodiment 1.
Embodiment 26: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1180g, Radix Angelicae Dahuricae 300g.
Its preparation method is with embodiment 1.
Embodiment 27: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1100g, Radix Polygoni Multiflori 380g, Radix Angelicae Dahuricae 250g.
Its preparation method is with embodiment 1.
Embodiment 28: the leukodermic medicine of a kind of treatment, its composition of raw materials is: bright blue or green Folium paulowniae 1000g, Fructus Psoraleae 180g, Radix Polygoni Multiflori 380g, Fructus Atriplicis Sibiricae 200g, Radix Angelicae Dahuricae 280g, vitamin C 280g, levamisole 7000mg.
Basically with embodiment 1, difference is its preparation method: vitamin C and levamisole directly are added in the cream that is boiled into, and stir.
Claims (2)
1. the leukodermic medicine of treatment is characterized in that, the crude drug in its preparation raw material is: bright blue or green Folium paulowniae 1100g, Radix Polygoni Multiflori 300g, Fructus Psoraleae 300g, Fructus Atriplicis Sibiricae 100g and Radix Angelicae Dahuricae 300g.
2. the leukodermic medicine of treatment is characterized in that, the crude drug in its preparation raw material is: bright blue or green Folium paulowniae 1000g, Radix Polygoni Multiflori 260g, Fructus Psoraleae 280g, Fructus Atriplicis Sibiricae 200g and Radix Angelicae Dahuricae 300g.
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| CN103655740A (en) * | 2012-09-26 | 2014-03-26 | 刘良柱 | Traditional Chinese medicine preparation for treating leucoderma |
| CN103493933A (en) * | 2013-10-15 | 2014-01-08 | 北京绿源求证科技发展有限责任公司 | Healthcare food-made tea granules for improving leucoderma |
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|---|---|---|---|---|
| CN1098311A (en) * | 1994-02-02 | 1995-02-08 | 李庆和 | Treat leukodermic Chinese medicine Baiyuwan pill |
| CN1141174A (en) * | 1995-07-24 | 1997-01-29 | 苏国平 | External application lotion for treating vitiligo |
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2007
- 2007-05-08 CN CN2007100543525A patent/CN101176758B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1098311A (en) * | 1994-02-02 | 1995-02-08 | 李庆和 | Treat leukodermic Chinese medicine Baiyuwan pill |
| CN1141174A (en) * | 1995-07-24 | 1997-01-29 | 苏国平 | External application lotion for treating vitiligo |
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| CN101176758A (en) | 2008-05-14 |
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