CN1175436A

CN1175436A - Chinese patent drug for treatment of leukoderma

Info

Publication number: CN1175436A
Application number: CN 97104488
Authority: CN
Inventors: 苏新发; 李文明
Original assignee: Individual
Current assignee: Individual
Priority date: 1997-06-20
Filing date: 1997-06-20
Publication date: 1998-03-11

Abstract

A Chinese patent medicine for curing leukoderma is prepared from 13 Chinese-medicinal materials such as psoralea fruit, white puncturevine caltrop, fleece flower root, black sesame, red sage root, etc. and features high effective rate up to 98.4% and sure curative effect.

Description

Treat leukodermic Chinese patent medicine

The invention belongs to the leukodermic oral Chinese patent medicine of a kind of treatment.

Vitiligo is a kind of to occur the dermatosis that the depigmentation speckle is a feature on the skin, and the traditional Chinese medical science belongs to " vitiligo ", " grizzled " category.Doctor trained in Western medicine is still undetermined so far to its pathogeny, it is generally acknowledged with send that biography factor, autoimmune factor, melanocyte are destroyed and factors such as the neuro chemistry factor relevant, so still there is not specific short.The traditional Chinese medical science thinks that then primary disease and energy and blood of human body discord, internal injury caused by excess of seven emotions, hemorrhagic disorder and consumption of essence and stagnation of blood stasis etc. have substantial connection, so the leukodermic Chinese patent medicine of many treatments is arranged, has his own strong points, and deficiency is also respectively arranged, and generally speaking, primary disease still belongs to a kind of disease than refractory.

The present invention aims to provide that a kind of clinical effective rate is higher, the leukodermic oral Chinese patent medicine of the treatment of efficacy consolidation.

The technical scheme that realizes above-mentioned purpose is that raw material of Chinese medicine and the weight proportion of making this oral Chinese patent medicine are (b is Unit Weight part):

Fructus Psoraleae 50-70b Fructus Atriplicis Sibiricae 35-45b Radix Polygoni Multiflori 25-35b Semen Sesami Nigrum 25-35b

Radix Salviae Miltiorrhizae 17-23b Semen Persicae 17-23b Rhizoma Chuanxiong 12-18b Radix Angelicae Sinensis 12-18b

Radix Paeoniae Rubra 12-18b Stigma Croci 6-8b Fructus Lycii 17-23b Radix Astragali 17-23b

Moschus 0.4-0.6b

Above-mentioned Chinese medicine raw materials by weight proportion is made oral Chinese patent medicine.

It is considered herein that, vitiligo is a multiple factor and causing a disease, and majority is that ailment said due to cold or exposure is attacked outward in addition because prolonged illness is lost supports or internal injury caused by excess of seven emotions, cause disorder of QI and blood, obstruction of meridian, skin are given birth to white macula, and the generation of the state of an illness is with to develop same gas, blood, the stasis of blood relevant, so the principles of formulating prescriptions of the present invention are " blood circulation promoting and blood stasis dispelling; soothing the liver circulation of qi promoting, QI and blood regulating, cleaning heat and expelling wind ".Fructus Psoraleae, Fructus Atriplicis Sibiricae, Radix Polygoni Multiflori are principal agent in the side, and modern study confirms that Fructus Psoraleae contains psoralen, and the dermal melanin of increasing effect is arranged, and the energy blood vessel dilating, the growth of mould fungus inhibition; Fructus Atriplicis Sibiricae nature and flavor hardship, suffering, the suppressing the hyperactive liver dispelling wind is arranged, the dispelling wind for relieving itching effect, cure ancient times in the nationality " book on Chinese herbal medicine is looked for the truth " and claim " ... the whole body leucoderma unbearable person that scratches where it itches, obey this control invariably imitate "; The Radix Polygoni Multiflori removing toxicity for eliminating carbuncles is controlled wind stasis of blood pruritus, and vitiligo is had sure curative effect; Semen Sesami Nigrum, the Radix Astragali, Fructus Lycii enrich and benefit essence and blood, enriching yin and nourishing kidney, and the human body immunity improving ability is arranged, repair the effect of destroyed tissue; Radix Salviae Miltiorrhizae, Semen Persicae, Rhizoma Chuanxiong, Radix Angelicae Sinensis, Radix Paeoniae Rubra, Flos Carthami are drug for invigorating blood circulation and eliminating stasis, but dredging the meridian, QI and blood regulating; Moschus contains muscone, and the promoting blood circulation to restore menstrual flow effect is also arranged, and can strengthen the chromatogenous ability of skin.Full side's compatibility reaches blood circulation promoting and blood stasis dispelling, soothing the liver circulation of qi promoting, QI and blood regulating, the effect of cleaning heat and expelling wind.

The processing method of this medicine reaches method of administration for example:

1, get the Chinese medicine of respectively distinguishing the flavor of in the above-mentioned raw materials ratio, be processed into powder in the processing method of " Chinese Pharmacopoeia " medicine pill and add Mel in 1: 1.2 ratio again and make pill, every ball 9 grams obey twice every day, each 1-2 ball.

2, get the Chinese medicine of respectively distinguishing the flavor of in the above-mentioned raw materials ratio and choose decontamination by traditional method, pulverize is made powder.Take medicine each 4-6 gram every day 3 times.

Taking medicine two months is a course of treatment, cures mainly vitiligo.Period in a medicine diet excitant food is not taken by pregnant women.

186 routine clinical efficacy statistics:

Recovery from illness (white macula all disappears, and recovers the original colour of skin)-54 examples account for 29%;

Produce effects (white macula disappears more than 80%)-68 example accounts for 36.6%;

Effectively (white macula has the pigment island to occur)-61 examples account for 32.8%;

Invalid (treat two course of treatment no change)-3 examples account for 1.6%;

Above total effective rate is 98.4%, invalid 1.6%.

Model case

1, WANG XIAOYAN, 32 years old workman of Xinjiang Yi Li formation of woman first visit in April, 93

The patient is not relaxed because of contradictory and gloomy in the work, finds to rise white macula and constantly expansion over nearly 4 years on one's body, and is not of uniform size, once multi-treatment, the state of an illness is not controlled, requires Chinese traditional treatment then, face, neck, the trunk extremity of looking into the patient distribute coin to silver dollar depigmentation speckle not of uniform size, boundary is clear, and the edge pigment is obviously deepened, patient's dimly red tongue, white and thin fur, stringy pulse is diagnosed as vitiligo, is because due to the stagnation of QI due to depression of the liver.Take this medicine honeyed pill immediately, every day twice, each 2 balls were taken medicine 3 months, and the whole body white macula all disappears, and has obtained recovery from illness, did not have with anti-1 year and recurred.

2, Zhang Jianwei, man, 25 years old two bridge shop assistant of Urumqi City, first visit on June 18 in 93 year

The white macula that the patient stumbled on before half a year and neck week, the shoulder back of the body, upper limb occurs differing in size has to enlarge trend gradually, patient and with symptoms such as pharyngoxerosis, oliguria with reddish urine, constipations.Look into the above-mentioned position of the patient depigmentation speckle that differs in size, part skin lesion pigment increases the weight of red tip of the tongue, white and thin fur, floating-rolling pulse, dialectical: wind heat is attacked table, the last stagnation of QI is closed, and is diagnosed as vitiligo, advises this medicine of clothes, every day 3 honeyed pill, each 1 ball, month state of an illness of taking medicine no longer develops, continue and take medicine 2 months, white macula all disappears, and clinical cure is followed up a case by regular visits to and do not had recurrence in 1 year.

The case of clinical trial is not seen the person that has the toxicity.

Adopt this medicine treatment vitiligo clinical effective rate height, can reach 98.4%, and efficacy consolidation, toxicity is little.

Embodiment 1

This example adopts following Chinese medicinal raw materials to make:

Fructus Psoraleae 60g Fructus Atriplicis Sibiricae 40g Radix Polygoni Multiflori 30g Semen Sesami Nigrum 30g

Radix Salviae Miltiorrhizae 20g Semen Persicae 20g Rhizoma Chuanxiong 15g Radix Angelicae Sinensis 15g

Radix Paeoniae Rubra 15g Stigma Croci 8g Fructus Lycii 20g Radix Astragali 20g

Moschus 0.5g

Above-mentioned raw material of Chinese medicine is cleaned, dried, be crushed into powder, add Mel, make honeyed pill, every ball 9 grams in 1: 1.2 ratio.

Embodiment 2

This example adopts following Chinese medicinal raw materials to make (b is Unit Weight part):

Fructus Psoraleae 50b Fructus Atriplicis Sibiricae 35b Radix Polygoni Multiflori 35b Semen Sesami Nigrum 35b

Radix Salviae Miltiorrhizae 17b Semen Persicae 17b Rhizoma Chuanxiong 18b Radix Angelicae Sinensis 18b

Radix Paeoniae Rubra 12b Stigma Croci 6b Fructus Lycii 23b Radix Astragali 23b

Moschus 0.6b

Above-mentioned Chinese medicine raw materials by weight proportion is made the powder preparation formulation oral Chinese patent medicine by traditional method.

Embodiment 3

Fructus Psoraleae 70b Fructus Atriplicis Sibiricae 45b Radix Polygoni Multiflori 25b Semen Sesami Nigrum 25b

Radix Salviae Miltiorrhizae 23b Semen Persicae 23b Rhizoma Chuanxiong 12b Radix Angelicae Sinensis 12b

Radix Paeoniae Rubra 18b Stigma Croci 8b Fructus Lycii 17b Radix Astragali 17b

Moschus 0.4b

Claims

1, treat leukodermic Chinese patent medicine, it is characterized in that, raw material of Chinese medicine and the weight proportion of making this Chinese patent medicine are (b is Unit Weight part):

Moschus 0.4-0.6b

2, the leukodermic Chinese patent medicine of treatment according to claim 1 is characterized in that, raw material of Chinese medicine and the weight proportion of making this Chinese patent medicine are:

Radix Paeoniae Rubra 15g Stigma Croci 8g Fructus Lycii 20g Radix Astragali 20g

Moschus 0.5g

Above-mentioned raw material of Chinese medicine is made the oral Chinese patent medicine of honeyed pill dosage form.