CN102973820A

CN102973820A - Granules of Chinese patent drug for treating rheumatic and rheumatoid arthritis

Info

Publication number: CN102973820A
Application number: CN2011102633503A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2011-09-07
Filing date: 2011-09-07
Publication date: 2013-03-20

Abstract

The present invention discloses a preparation method for granules of Chinese patent drug for treating rheumatic and rheumatoid arthritis, belonging to the pharmaceutical field. The granules of the present invention are prepared by using astragalus, poria, pinellia, ground pine, Chinese angelica root, Sichuan lovage root, pubescent angelica root, notopterygium root, ledebouriella root, radix scrophulariae, radix rehmanniae, angelica root, asarum, cassia twig, cranesbill, horny goat weed, honey-fried licorice, coix seed, eucommia bark, and radix clematidis as raw materials, and via a specific process. The granules have the characteristics of being easy to take and little in side effects; have the efficacies of activating blood, resolving stasis, dispersing swelling and relieving pains, so patients suffered from rheumatoid arthritis and rheumatoid arthritis can take the granules; and after taken, the granules is fast in absorption, rapid to take effect, and stable in efficacy.

Description

A kind of Chinese patent medicine particles for the treatment of rheumatic and rheumatoid arthritis

Technical field:

Product of the present invention belongs to pharmaceutical field, relates in particular to a kind of compound method for the treatment of rheumatic and rheumatoid arthritis Chinese patent medicine particles.

Background technology:

Arthritis is a kind of common chronic disease, and the arthritis pathological changes by inflammation, infection, wound or other factors cause common are osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, gouty arthritis etc.; Reason according to morbidity can be divided into constitutional arthritis and post-traumatic arthritis again, and post-traumatic arthritis has following factors to cause: 1. suffer from acute or the diseases such as chronic purulent arthritis, tuberculosis of joint, rheumatoid arthritis after the secondary primary disease; 2. intra-articular fracture causes; 3. arthrodyasplasia; 4. lopsided outside the joint; 5. joint instability is such as ligament, loosening of articular capsule; 6. long-term taking glucocorticoid or intra-articular injection hormone cause; 7. overweight; 8. muscle weakness; 9. the joint overuses.One or more combineds effect of above-mentioned factor form post-traumatic arthritis.Modal arthritis is rheumatic arthritis and rheumatoid arthritis, rheumatic arthritis is more common in the adult, often betide the large joint such as knee joint, shoulder, elbow, wrist, morbidity is many after upper respiratory tract infection, migration arthralgia, the swollen performance that reaches heating and other rheumatic fever occur; Rheumatoid arthritis is more common in person between twenty and fifty, and onset is slow, often betides the little joint of brothers and sacroiliac, and involves gradually the whole body joint, and that initial diseased joints also shows is red, swollen, bitterly and inconvenient activity etc., for a long time joint deformity or tetanic then.The present invention is a kind of Chinese patent medicine particles that rheumatic arthritis and rheumatoid arthritis are taken for the treatment of, with the Radix Astragali, Poria, the Rhizoma Pinelliae, Herba Lycopodii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Scrophulariae, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Herba Asari, Ramulus Cinnamomi, geranium, Herba Epimedii, Radix Glycyrrhizae Preparata, Semen Coicis, the Cortex Eucommiae, Radix Clematidis is that raw material is formulated by specific technique, characteristics are taking conveniences, side effect is little, after the patient of rheumatic arthritis and rheumatoid joint takes, has blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain, and absorb fast, rapid-action, effect rapidly, stable curative effect.

Summary of the invention:

The problem that the present invention mainly solves provides the compound method of a kind for the treatment of rheumatic and rheumatoid arthritis Chinese patent medicine particles, this Chinese patent medicine particles is for the treatment for the treatment of rheumatic and rheumatoid arthritis and special the preparation, it is little to take rear side effect, have the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, and absorb fast, rapid-action, effect rapidly, stable curative effect.Producing the raw material that this product uses has: the Radix Astragali 8%, Poria 6%, the Rhizoma Pinelliae 5%, Herba Lycopodii 3%, Radix Angelicae Sinensis 5%, Rhizoma Chuanxiong 3%, Radix Angelicae Pubescentis 4%, Rhizoma Et Radix Notopterygii 4%, Radix Saposhnikoviae 6%, Radix Scrophulariae 3%, the Radix Rehmanniae 6%, the Rhizoma Atractylodis Macrocephalae 6%, Herba Asari 5%, Ramulus Cinnamomi 5%, geranium 5%, Herba Epimedii 4%, Radix Glycyrrhizae Preparata 6%, Semen Coicis 4%, the Cortex Eucommiae 6%, Radix Clematidis 5%, water are an amount of, more than 20 kinds of Chinese crude drugs boil the clear paste that medicinal liquid makes and account for 70%～75% of final amt, sucrose and dextrin account for 25%～30% in the ratio preparation of 1:1.5.

The present invention can be achieved through the following technical solutions:

The method of a kind of batch preparation treatment rheumatic and rheumatoid arthritis Chinese patent medicine particles, its feature is made of following steps:

1. the Radix Astragali, Poria, the Rhizoma Pinelliae, Herba Lycopodii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Scrophulariae, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Herba Asari, Ramulus Cinnamomi, geranium, Herba Epimedii, Radix Glycyrrhizae Preparata, Semen Coicis, the Cortex Eucommiae, Radix Clematidis are sent into and boiled container, the water that adds for the first time 4.5 times of medical material quantity boils, and the time is to pour out a liquid after 2 hours; The water that adds for the second time 4 times of medical material quantity boils, and the time is to pour out two liquid after 1.5 hours; The water that adds for the third time 3 times of medical material quantity boils, and the time is to pour out three liquid after 1.2 hours, places mixing behind a liquid, two liquid, the three liquid elimination impurity.

2. the mixed liquor of a liquid, two liquid, three liquid is sent into thickener, the concentrated relative density that becomes is 1.4 clear paste.

3. mix rear in the ratio of 1:1.5 sucrose and dextrin and the clear paste mixing, stir with Mixing Machine, dry behind granulator granulation, get product.

The beneficial effect of product of the present invention is: a kind of compound method for the treatment of rheumatic and rheumatoid arthritis Chinese patent medicine particles is provided, this granule taking convenience, side effect are little, have the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain after rheumatic and patient with rheumatoid arthritis are taken, and absorb fast, rapid-action, effect rapidly, stable curative effect.

The specific embodiment:

Embodiment 1:

Be that 8% the Radix Astragali, 6% Poria, 5% the Rhizoma Pinelliae, 3% Herba Lycopodii, 5% Radix Angelicae Sinensis, 3% Rhizoma Chuanxiong, 4% Radix Angelicae Pubescentis, 4% Rhizoma Et Radix Notopterygii, 6% Radix Saposhnikoviae, 3% Radix Scrophulariae, 6% the Radix Rehmanniae, 6% the Rhizoma Atractylodis Macrocephalae, 5% Herba Asari, 5% Ramulus Cinnamomi, 5% geranium, 4% Herba Epimedii, 6% Radix Glycyrrhizae Preparata, 4% Semen Coicis, 6% the Cortex Eucommiae, 5% Radix Clematidis are sent into and boiled container with accounting for total amount, the water that adds for the first time 4.5 times of medical material quantity boils, and the time is to pour out a liquid after 2 hours; The water that adds for the second time 4 times of medical material quantity boils, and the time is to pour out two liquid after 1.5 hours; The water that adds for the third time 3 times of medical material quantity boils, and the time is to pour out three liquid after 1.2 hours, places mixing behind a liquid, two liquid, the three liquid elimination impurity; The mixed liquor of a liquid, two liquid, three liquid is sent into thickener, and the concentrated relative density that becomes is 1.4 clear paste, and the clear paste quantity that is condensed into accounts for 70% of final amt; Sucrose and dextrin are accounted for 30% of final amt after the ratio mixing in 1:1.5, then mix with clear paste, stir with Mixing Machine, dry behind granulator granulation, get product.

Embodiment 2:

Be that 8% the Radix Astragali, 6% Poria, 5% the Rhizoma Pinelliae, 3% Herba Lycopodii, 5% Radix Angelicae Sinensis, 3% Rhizoma Chuanxiong, 4% Radix Angelicae Pubescentis, 4% Rhizoma Et Radix Notopterygii, 6% Radix Saposhnikoviae, 3% Radix Scrophulariae, 6% the Radix Rehmanniae, 6% the Rhizoma Atractylodis Macrocephalae, 5% Herba Asari, 5% Ramulus Cinnamomi, 5% geranium, 4% Herba Epimedii, 6% Radix Glycyrrhizae Preparata, 4% Semen Coicis, 6% the Cortex Eucommiae, 5% Radix Clematidis are sent into and boiled container with accounting for total amount, the water that adds for the first time 4.5 times of medical material quantity boils, and the time is to pour out a liquid after 2 hours; The water that adds for the second time 4 times of medical material quantity boils, and the time is to pour out two liquid after 1.5 hours; The water that adds for the third time 3 times of medical material quantity boils, and the time is to pour out three liquid after 1.2 hours, places mixing behind a liquid, two liquid, the three liquid elimination impurity; The mixed liquor of a liquid, two liquid, three liquid is sent into thickener, and the concentrated relative density that becomes is 1.4 clear paste, and the clear paste quantity that is condensed into accounts for 72.5% of final amt; Sucrose and dextrin are accounted for 27.5% of final amt after the ratio mixing in 1:1.5, then mix with clear paste, stir with Mixing Machine, dry behind granulator granulation, get product.

Embodiment 3:

Be that 8% the Radix Astragali, 6% Poria, 5% the Rhizoma Pinelliae, 3% Herba Lycopodii, 5% Radix Angelicae Sinensis, 3% Rhizoma Chuanxiong, 4% Radix Angelicae Pubescentis, 4% Rhizoma Et Radix Notopterygii, 6% Radix Saposhnikoviae, 3% Radix Scrophulariae, 6% the Radix Rehmanniae, 6% the Rhizoma Atractylodis Macrocephalae, 5% Herba Asari, 5% Ramulus Cinnamomi, 5% geranium, 4% Herba Epimedii, 6% Radix Glycyrrhizae Preparata, 4% Semen Coicis, 6% the Cortex Eucommiae, 5% Radix Clematidis are sent into and boiled container with accounting for total amount, the water that adds for the first time 4.5 times of medical material quantity boils, and the time is to pour out a liquid after 2 hours; The water that adds for the second time 4 times of medical material quantity boils, and the time is to pour out two liquid after 1.5 hours; The water that adds for the third time 3 times of medical material quantity boils, and the time is to pour out three liquid after 1.2 hours, places mixing behind a liquid, two liquid, the three liquid elimination impurity; The mixed liquor of a liquid, two liquid, three liquid is sent into thickener, and the concentrated relative density that becomes is 1.4 clear paste, and the clear paste quantity that is condensed into accounts for 75% of final amt; Sucrose and dextrin are accounted for 25% of final amt after the ratio mixing in 1:1.5, then mix with clear paste, stir with Mixing Machine, dry behind granulator granulation, get product.

Claims

1. Chinese patent medicine particles for the treatment of rheumatic and rheumatoid arthritis, it is characterized in that: with the Radix Astragali 8%, Poria 6%, the Rhizoma Pinelliae 5%, Herba Lycopodii 3%, Radix Angelicae Sinensis 5%, Rhizoma Chuanxiong 3%, Radix Angelicae Pubescentis 4%, Rhizoma Et Radix Notopterygii 4%, Radix Saposhnikoviae 6%, Radix Scrophulariae 3%, the Radix Rehmanniae 6%, the Rhizoma Atractylodis Macrocephalae 6%, Herba Asari 5%, Ramulus Cinnamomi 5%, geranium 5%, Herba Epimedii 4%, Radix Glycyrrhizae Preparata 6%, Semen Coicis 4%, the Cortex Eucommiae 6%, Radix Clematidis 5%, water is an amount of, more than 20 kinds of Chinese crude drugs boil the clear paste that medicinal liquid makes and account for 70%～75% of final amt, sucrose and dextrin account for 25%～30% in the ratio preparation of 1:1.5 and are raw material, obtain finished product by following steps.

2. a kind of Chinese patent medicine particles for the treatment of rheumatic and rheumatoid arthritis according to claim 1, the feature of its first step is: the Radix Astragali, Poria, the Rhizoma Pinelliae, Herba Lycopodii, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Saposhnikoviae, Radix Scrophulariae, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Herba Asari, Ramulus Cinnamomi, geranium, Herba Epimedii, Radix Glycyrrhizae Preparata, Semen Coicis, the Cortex Eucommiae, Radix Clematidis are sent into boiled container, the water that adds for the first time 4.5 times of medical material quantity boils, and the time is to pour out a liquid after 2 hours; The water that adds for the second time 4 times of medical material quantity boils, and the time is to pour out two liquid after 1.5 hours; The water that adds for the third time 3 times of medical material quantity boils, and the time is to pour out three liquid after 1.2 hours, places mixing behind a liquid, two liquid, the three liquid elimination impurity.

3. a kind of Chinese patent medicine particles for the treatment of rheumatic and rheumatoid arthritis according to claim 1, the feature of its second step is: the mixed liquor of a liquid, two liquid, three liquid is sent into thickener, and the concentrated relative density that becomes is 1.4 clear paste.

4. a kind of Chinese patent medicine particles for the treatment of rheumatic and rheumatoid arthritis according to claim 1; the feature in its 3rd step is: mix rear in the ratio of 1:1.5 sucrose and dextrin and the clear paste mixing; stir with Mixing Machine, dry behind granulator granulation, get product.