CN102247448A - Traditional Chinese herbal external washout powder for treating rheumatoid arthritis, effervescent tablet formula and preparation method thereof - Google Patents
Traditional Chinese herbal external washout powder for treating rheumatoid arthritis, effervescent tablet formula and preparation method thereof Download PDFInfo
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- CN102247448A CN102247448A CN2010106019408A CN201010601940A CN102247448A CN 102247448 A CN102247448 A CN 102247448A CN 2010106019408 A CN2010106019408 A CN 2010106019408A CN 201010601940 A CN201010601940 A CN 201010601940A CN 102247448 A CN102247448 A CN 102247448A
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Abstract
The invention relates to a traditional Chinese herbal external washout powder for treating rheumatoid arthritis, an effervescent tablet formula and preparation methods thereof. The formula of the external washout powder comprises 3750g of notopterygium root, 6250g of ramulus mori, 3750g of Radix Angelicae Pubescentis, 3125g of clematis root and 3125g of Radix Aconiti preparata. The preparation method of the external washout powder comprises the following steps of: weighing the traditional Chinese medicines of the above formula by weight, respectively crushing the traditional Chinese medicines to 200 meshes, uniformly stirring, and packaging according to 20g /bag to obtain the external washout powder. The effervescent tablet formula comprises raw medicines and excipients, wherein the raw medicines contain 690g of notopterygium root, 1110g of ramulus mori, 690g of levisticum, 520g of clematis root and 520g of Radix Aconiti preparata, and the excipients contain 650g of citric acid, 780g of sodium bicarbonate, 1105g of starch, 260g of sodium carboxymethyl starch, 195g of hydroxy propyl cellulose and 6000195g of polyethylene glycol. The preparation method of the external washout effervescent tablet comprises the following steps of: (1) preparing an extract powder; (2) dividing the above extract fine powder into two portions, adding 650g of a citric acid fine powder into one portion of the extract fine powder, followed by uniformly blending, granulating, drying and finishing the granules; adding 780g of a sodium bicarbonate fine powder into the other portion of the extract fine powder, followed by uniformly blending, granulating, drying and finishing the granules; (3) adding 195g of hydroxypropyl cellulose and 6000195g of polyethylene glycol into the above granules, uniformly blending, followed by pressing into tablets.
Description
Technical field
The present invention relates to prescription of a kind of external washout with traditional Chinese herbs powder, effervescent tablet and preparation method thereof, relate in particular to a kind of external washout with traditional Chinese herbs powder, effervescent tablet for the treatment of rheumatoid arthritis and fill a prescription and preparation method thereof.
Background technology
Rheumatoid arthritis (rheumatoid arthritis) be a kind of be the chronic systemic autoimmune disease of feature with the articular synovitis, synovitis is outbreak repeatedly lastingly, the destruction that can cause intraarticular cartilage and bone, joint function disturbance, even maimed.
Rheumatoid arthritis claims rheumatoid (RA) again, is the chronic systemic inflammatory disease that a kind of cause of disease is not understood as yet, is main clinical manifestation with pathological changes outside chronic, symmetry, many synovial jointss inflammation and the joint, belongs to the autoimmune inflammatory diseases.This disease is sent out well in little joints such as hands, wrist, foots, and outbreak is symmetrical distribution repeatedly.Joint red and swollen heat pain and dysfunction are arranged in early days, late period, stiff deformity in various degree can appear in the joint, and with bone and skeletal muscle atrophy, very easily disable, angle from pathological change, rheumatoid arthritis is a kind of synovium of joint that mainly involves, and can feed through to articular cartilage, osseous tissue, articular ligament and flesh key later on, is the popularity diseases associated with inflammation of connective tissues such as serous coat, the heart, lung and eye secondly.The general performance of rheumatoid arthritis is except that arthropathy, also have heating, fatigue and weak, pericarditis, subcutaneous nodule, pleuritis, arteritis, peripheral neuropathy etc., generalized rheumatoid arthritis also comprises the popularity pathological changes of whole body except that the inflammatory disorders of joint part.
Foot almost has all over echo area in other words, the acupuncture point of logical whole body, foot bath has safety, no pain, has no side effect, cheap, effectively, convenient, comfortable advantage, ancients sum up " foot bath in spring, yang invigorating takes off admittedly; The foot bath in summer, heat-damp in summer can be dispelled; Autumn Xian's foot, the lung intestine moistening is moistened; Winter Xian's foot, public region Wen Zhuo ", this is meant the warm water foot bath, in recent years, foot care is exactly the portrayal that above-mentioned theory is rooted in the hearts of the people by generally accepting; The pedicure of Chinese medicine decoction foot care is used very generally, and its prescription mostly is existing raw material of Chinese medicine and repeatedly boils merging filtrate, does time-consuming expense manpower expense thing material like this.
Traditional Chinese medical science extensive knowledge and profound scholarship for rheumatoid arthritis patients being alleviated or eliminating misery, in conjunction with traditional foot care therapy, provides following invention.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of washing with conveniently, effectively being used for the treatment of rheumatoid arthritis external washout with traditional Chinese herbs powder, effervescent tablet prescription and preparation method thereof.
Pharmacological action: Ramulus Mori dispelling wind and removing obstruction in the collateral; Rhizoma Et Radix Notopterygii expelling cold and relieving exterior syndrome, expelling wind and dampness, eliminating impediment pain relieving; Radix Angelicae Pubescentis expelling wind and removing dampness, numbness relieving and pain relieving; The Radix Clematidis expelling wind and removing dampness, removing obstruction in the collateral to relieve pain; The Radix Aconiti Preparata anti-inflammatory and antalgic.
The prescription of treatment rheumatoid arthritis external washout with traditional Chinese herbs powder:
Rhizoma Et Radix Notopterygii 3750g, Ramulus Mori 6250g, Radix Angelicae Pubescentis 3750g, Radix Clematidis 3125g, Radix Aconiti Preparata 3125g.
The preparation method of treatment rheumatoid arthritis external washout with traditional Chinese herbs powder:
More than prescription Chinese medicine takes by weighing by weight, and the pulverize separately pulverizing becomes 200 orders, stirs, and packs according to 20g/, obtains 1000 and guarantees to cure treatment rheumatoid arthritis external washout with traditional Chinese herbs powder.
The prescription of treatment rheumatoid arthritis external washout with traditional Chinese herbs effervescent tablet:
Crude drug: Rhizoma Et Radix Notopterygii 690g, Ramulus Mori 1110g, Radix Angelicae Pubescentis 690g, Radix Clematidis 520g, Radix Aconiti Preparata 520 g;
Adjuvant: citric acid 650g, sodium bicarbonate 780g, starch 1105g, carboxymethyl starch sodium 260g, hydroxypropyl cellulose 195g, polyethylene glycol 6000 195g.
The preparation method of treatment rheumatoid arthritis external washout with traditional Chinese herbs effervescent tablet:
(1) preparation extract powder: Rhizoma Et Radix Notopterygii 690 g, Ramulus Mori 1110 g, Radix Angelicae Pubescentis 690 g, Radix Clematidis 520 g, Radix Aconiti Preparata 520 g decoct with water three times, add for the first time three times of water, add two times of water for the second time, water for the third time doubles, merge three times decocting liquid, filter, filtrate is concentrated into the thick paste that relative density is 1.25-1.30, adds starch 1105g, carboxymethyl starch sodium 260g, mixing, cold drying is ground into fine powder, and is standby;
(2) above-mentioned extractum fine powder is divided into two parts, a adding citric acid 650g fine powder mixing is made granule, 80 ℃ of dryings, and granule is standby behind the granulate; Another part adds sodium bicarbonate 780g fine powder mixing, makes granule, 80 ℃ of dryings, and granule is standby behind the granulate;
(3) above-mentioned granule adds hydroxypropyl cellulose 195g, polyethylene glycol 6000 195g, and mixing is pressed into 1000.
Beneficial effect: the present invention is easy to use, and used Chinese crude drug is homemade medical material in the composition, and adjuvant is easy to get, and cost is low, helps large-scale industrialized production, and every day 2 times, 10 is a course of treatment, the tenderness sx of rheumatoid arthritis after course of treatment.
The specific embodiment
One, preparation treatment rheumatoid arthritis external washout with traditional Chinese herbs powder:
Take by weighing Rhizoma Et Radix Notopterygii 3750g, Ramulus Mori 6250g, Radix Angelicae Pubescentis 3750g, Radix Clematidis 3125g, Radix Aconiti Preparata 3125g, the pulverize separately pulverizing becomes 200 orders, stirs, and packs according to 20g/, obtains 1000 and guarantees to cure treatment rheumatoid arthritis external washout with traditional Chinese herbs powder.
Two, preparation treatment rheumatoid arthritis external washout with traditional Chinese herbs effervescent tablet:
(1) preparation extract powder: Rhizoma Et Radix Notopterygii 690 g, Ramulus Mori 1110 g, Radix Angelicae Pubescentis 690 g, Radix Clematidis 520 g, Radix Aconiti Preparata 520 g decoct with water three times, add for the first time three times of water, add two times of water for the second time, water for the third time doubles, merge three times decocting liquid, filter, filtrate is concentrated into the thick paste that relative density is 1.25-1.30, adds starch 1105g, carboxymethyl starch sodium 260g, mixing, cold drying is ground into fine powder, and is standby;
(2) above-mentioned extractum fine powder is divided into two parts, a adding citric acid 650g fine powder mixing is made granule, 80 ℃ of dryings, and granule is standby behind the granulate; Another part adds sodium bicarbonate 780g fine powder mixing, makes granule, 80 ℃ of dryings, and granule is standby behind the granulate;
(3) above-mentioned granule adds hydroxypropyl cellulose 195g, polyethylene glycol 6000 195g, mixing, and compacting promptly gets 1000 rheumatoid arthritis external washout with traditional Chinese herbs effervescent tablets in flakes.
Can make medicament greater or less than above-mentioned amount in the ratio of above-mentioned prescription plus-minus dose, for example each medical material takes by weighing by two times, can make duple medicament.
Claims (4)
1. prescription for the treatment of rheumatoid arthritis external washout with traditional Chinese herbs powder, its prescription comprises: Rhizoma Et Radix Notopterygii 3750g, Ramulus Mori 6250g, Radix Angelicae Pubescentis 3750g, Radix Clematidis 3125g, Radix Aconiti Preparata 3125g.
2. preparation method for the treatment of rheumatoid arthritis external washout with traditional Chinese herbs powder, its preparation method may further comprise the steps: take by weighing Rhizoma Et Radix Notopterygii 3750g, Ramulus Mori 6250g, Radix Angelicae Pubescentis 3750g, Radix Clematidis 3125g, Radix Aconiti Preparata 3125g, the pulverize separately pulverizing becomes 200 orders, stir, pack according to 20g/, obtain 1000 and guarantee to cure treatment rheumatoid arthritis external washout with traditional Chinese herbs powder.
3. prescription for the treatment of rheumatoid arthritis Chinese medicine effervescent tablet, its prescription comprises:
Crude drug: Rhizoma Et Radix Notopterygii 690g, Ramulus Mori 1110g, Radix Angelicae Pubescentis 690g, Radix Clematidis 520g, Radix Aconiti Preparata 520 g;
Adjuvant: citric acid 650g, sodium bicarbonate 780g, starch 1105g, carboxymethyl starch sodium 260g, hydroxypropyl cellulose 195g, polyethylene glycol 6000 195g.
4. preparation method for the treatment of rheumatoid arthritis Chinese medicine effervescent tablet, its preparation method may further comprise the steps:
(1) preparation extract powder: Rhizoma Et Radix Notopterygii 690 g, Ramulus Mori 1110 g, Radix Angelicae Pubescentis 690 g, Radix Clematidis 520 g, Radix Aconiti Preparata 520 g decoct with water three times, add for the first time three times of water, add two times of water for the second time, water for the third time doubles, merge three times decocting liquid, filter, filtrate is concentrated into the thick paste that relative density is 1.25-1.30, adds starch 1105g, carboxymethyl starch sodium 260g, mixing, cold drying is ground into fine powder, and is standby;
(2) above-mentioned extractum fine powder is divided into two parts, a adding citric acid 650g fine powder mixing is made granule, 80 ℃ of dryings, and granule is standby behind the granulate; Another part adds sodium bicarbonate 780g fine powder mixing, makes granule, 80 ℃ of dryings, and granule is standby behind the granulate;
(3) above-mentioned granule adds hydroxypropyl cellulose 195g, polyethylene glycol 6000 195g, and mixing is pressed into 1000, promptly gets to treat 1000 of rheumatoid arthritis Chinese medicine effervescent tablets.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526327A (en) * | 2012-02-13 | 2012-07-04 | 李连君 | Compound Chinese herbal medicine for treating rheumatoid bone disease and preparation method for compound Chinese herbal medicine |
| CN102579727A (en) * | 2012-03-02 | 2012-07-18 | 黄凤鸣 | Acupoint pasting plaster |
| CN102697887A (en) * | 2012-06-26 | 2012-10-03 | 南京辰逸生物科技有限公司 | Traditional Chinese medicine composition for treating rheumatoid arthritis |
| CN103211877A (en) * | 2013-02-21 | 2013-07-24 | 盐城恩源堂生物科技有限公司 | Physiotherapy liquid for treating aches of neck, shoulder, waist and leg |
| CN113197925A (en) * | 2021-05-13 | 2021-08-03 | 郭亮生 | Pharmaceutical composition, preparation method thereof, external medicine and application |
-
2010
- 2010-12-23 CN CN2010106019408A patent/CN102247448A/en active Pending
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102526327A (en) * | 2012-02-13 | 2012-07-04 | 李连君 | Compound Chinese herbal medicine for treating rheumatoid bone disease and preparation method for compound Chinese herbal medicine |
| CN102526327B (en) * | 2012-02-13 | 2013-09-18 | 李连君 | Compound Chinese herbal medicine for treating rheumatoid bone disease and preparation method for compound Chinese herbal medicine |
| CN102579727A (en) * | 2012-03-02 | 2012-07-18 | 黄凤鸣 | Acupoint pasting plaster |
| CN102697887A (en) * | 2012-06-26 | 2012-10-03 | 南京辰逸生物科技有限公司 | Traditional Chinese medicine composition for treating rheumatoid arthritis |
| CN103211877A (en) * | 2013-02-21 | 2013-07-24 | 盐城恩源堂生物科技有限公司 | Physiotherapy liquid for treating aches of neck, shoulder, waist and leg |
| CN113197925A (en) * | 2021-05-13 | 2021-08-03 | 郭亮生 | Pharmaceutical composition, preparation method thereof, external medicine and application |
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Application publication date: 20111123 |