CN103656545A - Chinese patent medicine granule for treating arthritis - Google Patents

Abstract

The invention discloses a production method of a Chinese patent medicine granule for treating arthritis. The product belongs to the pharmaceutical field. The Chinese patent medicine granule is prepared with sucrose and dextrin by taking eucommia ulmoides, burdock, phryma leptostachya, erodium stephanianum wild, prepared radix licorice, ephedra herb, radix aconiti preparata, radix aconiti kusnezoffi preparata, smoked plum, radix lithospermi, achyranthes bidentata, nux vomica, pangolin, ginger, dried rehamnnia root, white atractylodes rhizome and cassia twigs as materials through a special process. The product disclosed by the invention has characteristics of being convenient to take and small in side effect, has better curative effect for rheumatic arthritis; after being taken by a patient with the rheumatic arthritis, the Chinese patent medicine granule has effects of promoting blood circulation to remove blood stasis and relieving swelling and pain, and is quick to absorb, rapid in effect taking and stable in curative effect. Dosage of the Chinese patent medicine granule is as follows: 5g, twice a day, with warm water boiled water after a meal half an hour later.

Description

A kind of Chinese patent medicine particles for the treatment of of arthritis

Technical field:

Product of the present invention belongs to pharmaceutical field, relates in particular to a kind of Chinese patent medicine particles for the treatment of of arthritis.

Background technology:

Arthritis general reference occurs in the inflammatory diseases of human synovial and surrounding tissue thereof, can be divided into tens of kinds, clinical manifestation be joint red, swollen, hot, bitterly, dysfunction and joint deformity, severe patient causes joint deformity, affects patients ' life quality, the arthritic cause of disease is complicated, mainly relevant with the factor such as inflammation, autoimmune response, infection, metabolism disorder, wound, degeneration.Clinical common arthritis mainly comprises following several: rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, gouty arthritis, reactive arthritis, infective arthritis, traumatic arthritis, psoriatic arthritis, enteropathic arthritis, and arthritic cardinal symptom is: 1. pain; 2. swelling; 3. dysfunction, in addition, can also there is redness and swelling of joints in actute infection arthritis.Arthritis is of a great variety, the cause of disease is complicated, modal is rheumatoid arthritis, it is generally acknowledged with heredity, antibacterial and viral infection, environmental factors and comprise that smoking is relevant with heredity, can occur in any age, but 40-60 year women is more common, common with the little joint involvement of both hands, and shows as bilateral and get involved, simultaneously with rising morning, ankylosis sense continues to be greater than 1 hour to patient and joint motion is limited, can occur that whole body internal organs get involved while being in a bad way.The present invention is a kind of Chinese patent medicine particles that rheumatic arthritis is taken for the treatment of, take the Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae, geranium, Radix Glycyrrhizae Preparata, Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Fructus Mume, Radix Arnebiae (Radix Lithospermi), cattle paint, Semen Strychni, roasted SQUAMA MANITIS into puffy with sand, Rhizoma Zingiberis Recens, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi as raw material formulated by specific technique, wherein the Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae are main medicine, Cortex Eucommiae sweet in the mouth, warm in nature, there is liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, treatment arthralgia or aching and limp unable effect; Fructus Arctii has dispelling wind and heat pathogens, heat-clearing and toxic substances removing rash, the loose swollen effect of lung qi dispersing sore-throat relieving; Herba speranskiae tuberculatae has wind-damp dispelling, invigorates blood circulation, the effect of relaxing muscles and tendons, pain relieving, and dispelling the wind and dampness pathogens pain, sprain and contusion wound, innominate toxic swelling are had to obvious curative effect.The feature of product of the present invention is that taking convenience, side effect are little, and rheumatic arthritis is had to good curative effect, after the patient of rheumatic arthritis takes, has the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, and absorption is fast, effect is rapid, stable curative effect.

Summary of the invention:

The problem that the present invention mainly solves is to provide a kind of compound method of Chinese patent medicine particles for the treatment of of arthritis, this Chinese patent medicine particles is to be adapted to treat rheumatic arthritis, have that side effect is little, the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, and absorb fast, effect rapidly, stable curative effect.Producing the raw material that this product uses has: the Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae, geranium, Radix Glycyrrhizae Preparata, Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Fructus Mume, Radix Arnebiae (Radix Lithospermi), cattle paint, Semen Strychni, roasted SQUAMA MANITIS into puffy with sand, Rhizoma Zingiberis Recens, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi totally 17 kinds of Chinese crude drug clear paste that reconcentration is made after boiling account for the 72%-74% of final weight, and sucrose and dextrin account for the 26%-28% of final weight in the ratio preparation of 1:1.2.

The present invention can be achieved through the following technical solutions:

A method for the Chinese patent medicine particles of batch preparation treatment of arthritis, its feature consists of following steps:

(1) Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae, geranium, Radix Glycyrrhizae Preparata, Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Fructus Mume, Radix Arnebiae (Radix Lithospermi), cattle paint, Semen Strychni, roasted SQUAMA MANITIS into puffy with sand, Rhizoma Zingiberis Recens, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi are sent into and boiled container, the water that adds for the first time 4 times of medical material quantity boils, first big fire is boiled by water, then slow fire is poured out a liquid after boiling 2 hours; The first big fire of water of adding for the second time 4 times of medical material quantity is boiled by water, then slow fire is poured out two liquid after boiling 2.5 hours; To after a liquid, two liquid elimination impurity, send into thickener, the concentrated relative density that becomes is 1.4 clear paste, accounts for the 72%-74% of final weight.

(2) account for the 26%-28% of final weight after sucrose and dextrin are mixed in the ratio of 1:1.2, then mix with clear paste, with Mixing Machine, stir, after granulator granulation, send into drying machine drying, get product.

(3) instructions of taking of this Chinese patent medicine particles is: every twice-daily, each 5 grams, after meal half an hour warm water delivery service.

The described Chinese crude drug formulation weight ratio of step (1) is: 11% Cortex Eucommiae, 7% Fructus Arctii, 11% Herba speranskiae tuberculatae, 4% geranium, 5% Radix Glycyrrhizae Preparata, 4% Herba Ephedrae, 4% Radix Aconiti Preparata, 5% Radix Aconiti Kusnezoffii Preparata, 5% Fructus Mume, 5% Radix Arnebiae (Radix Lithospermi), 6% N of paint, 5% Semen Strychni, 7% roasted SQUAMA MANITIS into puffy with sand, 7% Rhizoma Zingiberis Recens, 6% Radix Rehmanniae, 5% Rhizoma Atractylodis Macrocephalae, 4% Ramulus Cinnamomi.

The described bake out temperature of step (2) is 38-40 ℃.

The beneficial effect of product of the present invention is: a kind of compound method for the treatment of the Chinese patent medicine particles of rheumatic arthritis is provided, this granule taking convenience, side effect are little, after rheumatic arthritis patient takes, there is the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, and absorption is fast, effect is rapid, stable curative effect.

The specific embodiment:

Embodiment 1:

By weight ratio, be that 11% Cortex Eucommiae, 7% Fructus Arctii, 11% Herba speranskiae tuberculatae, 4% geranium, 5% Radix Glycyrrhizae Preparata, 4% Herba Ephedrae, 4% Radix Aconiti Preparata, 5% Radix Aconiti Kusnezoffii Preparata, 5% Fructus Mume, 5% Radix Arnebiae (Radix Lithospermi), 6% N of paint, 5% Semen Strychni, 7% roasted SQUAMA MANITIS into puffy with sand, 7% Rhizoma Zingiberis Recens, 6% Radix Rehmanniae, 5% Rhizoma Atractylodis Macrocephalae, 4% Ramulus Cinnamomi are sent into and boiled container, the water that adds for the first time 4 times of medical material quantity boils, first big fire is boiled by water, then slow fire is poured out a liquid after boiling 2 hours; The first big fire of water of adding for the second time 4 times of medical material quantity is boiled by water, then slow fire is poured out two liquid after boiling 2.5 hours; To after a liquid, two liquid elimination impurity, send into thickener, the concentrated relative density that becomes is 1.4 clear paste, accounts for 72% of final weight.After sucrose and dextrin are mixed in the ratio of 1:1.2, account for 28% of final weight, then mix with clear paste, with Mixing Machine, stir, after granulator granulation, send into drying machine drying, get product.The instructions of taking of this Chinese patent medicine particles is: every twice-daily, each 5 grams, after meal half an hour warm water delivery service.

Embodiment 2:

By weight ratio, be that 11% Cortex Eucommiae, 7% Fructus Arctii, 11% Herba speranskiae tuberculatae, 4% geranium, 5% Radix Glycyrrhizae Preparata, 4% Herba Ephedrae, 4% Radix Aconiti Preparata, 5% Radix Aconiti Kusnezoffii Preparata, 5% Fructus Mume, 5% Radix Arnebiae (Radix Lithospermi), 6% N of paint, 5% Semen Strychni, 7% roasted SQUAMA MANITIS into puffy with sand, 7% Rhizoma Zingiberis Recens, 6% Radix Rehmanniae, 5% Rhizoma Atractylodis Macrocephalae, 4% Ramulus Cinnamomi are sent into and boiled container, the water that adds for the first time 4 times of medical material quantity boils, first big fire is boiled by water, then slow fire is poured out a liquid after boiling 2 hours; The first big fire of water of adding for the second time 4 times of medical material quantity is boiled by water, then slow fire is poured out two liquid after boiling 2.5 hours; To after a liquid, two liquid elimination impurity, send into thickener, the concentrated relative density that becomes is 1.4 clear paste, accounts for 73% of final weight.After sucrose and dextrin are mixed in the ratio of 1:1.2, account for 27% of final weight, then mix with clear paste, with Mixing Machine, stir, after granulator granulation, send into drying machine drying, get product.The instructions of taking of this Chinese patent medicine particles is: every twice-daily, each 5 grams, after meal half an hour warm water delivery service.

Embodiment 3:

By weight ratio, be that 11% Cortex Eucommiae, 7% Fructus Arctii, 11% Herba speranskiae tuberculatae, 4% geranium, 5% Radix Glycyrrhizae Preparata, 4% Herba Ephedrae, 4% Radix Aconiti Preparata, 5% Radix Aconiti Kusnezoffii Preparata, 5% Fructus Mume, 5% Radix Arnebiae (Radix Lithospermi), 6% N of paint, 5% Semen Strychni, 7% roasted SQUAMA MANITIS into puffy with sand, 7% Rhizoma Zingiberis Recens, 6% Radix Rehmanniae, 5% Rhizoma Atractylodis Macrocephalae, 4% Ramulus Cinnamomi are sent into and boiled container, the water that adds for the first time 4 times of medical material quantity boils, first big fire is boiled by water, then slow fire is poured out a liquid after boiling 2 hours; The first big fire of water of adding for the second time 4 times of medical material quantity is boiled by water, then slow fire is poured out two liquid after boiling 2.5 hours; To after a liquid, two liquid elimination impurity, send into thickener, the concentrated relative density that becomes is 1.4 clear paste, accounts for 74% of final weight.After sucrose and dextrin are mixed in the ratio of 1:1.2, account for 26% of final weight, then mix with clear paste, with Mixing Machine, stir, after granulator granulation, send into drying machine drying, get product.The instructions of taking of this Chinese patent medicine particles is: every twice-daily, each 5 grams, after meal half an hour warm water delivery service.

Claims (4)

1. the Chinese patent medicine particles of a treatment of arthritis, the raw material of its use comprises: the Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae, geranium, Radix Glycyrrhizae Preparata, Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Fructus Mume, Radix Arnebiae (Radix Lithospermi), cattle paint, Semen Strychni, roasted SQUAMA MANITIS into puffy with sand, Rhizoma Zingiberis Recens, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi totally 17 kinds of Chinese crude drug clear paste that reconcentration is made after boiling account for the 72%-74% of final weight, and sucrose and dextrin account for the 26%-28% of final weight in the ratio preparation of 1:1.2; It is characterized in that: step (1) is sent into the Cortex Eucommiae, Fructus Arctii, Herba speranskiae tuberculatae, geranium, Radix Glycyrrhizae Preparata, Herba Ephedrae, Radix Aconiti Preparata, Radix Aconiti Kusnezoffii Preparata, Fructus Mume, Radix Arnebiae (Radix Lithospermi), cattle paint, Semen Strychni, roasted SQUAMA MANITIS into puffy with sand, Rhizoma Zingiberis Recens, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Ramulus Cinnamomi to boil container, the water that adds for the first time 4 times of medical material quantity boils, first big fire is boiled by water, then slow fire is poured out a liquid after boiling 2 hours; The first big fire of water of adding for the second time 4 times of medical material quantity is boiled by water, then slow fire is poured out two liquid after boiling 2.5 hours; To after a liquid, two liquid elimination impurity, send into thickener, the concentrated relative density that becomes is 1.4 clear paste, accounts for the 72%-74% of final weight; Step (2) accounts for the 26%-28% of final weight after sucrose and dextrin are mixed in the ratio of 1:1.2, then mix with clear paste, with Mixing Machine, stirs, and sends into drying machine drying after granulator granulation, gets product.

2. the Chinese patent medicine particles of a kind for the treatment of of arthritis according to claim 1, the feature of its step (1) is: described Chinese crude drug formulation weight ratio is: 11% Cortex Eucommiae, 7% Fructus Arctii, 11% Herba speranskiae tuberculatae, 4% geranium, 5% Radix Glycyrrhizae Preparata, 4% Herba Ephedrae, 4% Radix Aconiti Preparata, 5% Radix Aconiti Kusnezoffii Preparata, 5% Fructus Mume, 5% Radix Arnebiae (Radix Lithospermi), 6% N of paint, 5% Semen Strychni, 7% roasted SQUAMA MANITIS into puffy with sand, 7% Rhizoma Zingiberis Recens, 6% Radix Rehmanniae, 5% Rhizoma Atractylodis Macrocephalae, 4% Ramulus Cinnamomi.

3. the Chinese patent medicine particles of a kind for the treatment of of arthritis according to claim 1, the feature of its step (2) is: described bake out temperature is 38-40 ℃.

4. the Chinese patent medicine particles of a kind for the treatment of of arthritis according to claim 1, its using method is: every twice-daily, each 5 grams, after meal half an hour warm water delivery service.