CN102972672A - Drug composite effervescent granule for supplementing nutrition and preparation method thereof - Google Patents

Abstract

The invention discloses a drug composite effervescent granule for supplementing nutrition and a preparation method thereof. The drug composite effervescent granule contains the following components in parts by weight: 20 parts of moringa oleifera extracts, 40 parts of anhydrous glucoses, 20 parts of mannitol, 8.6 parts of citric acids and 11.4 parts of sodium bicarbonate. The effervescent granule disclosed by the invention takes affinal drug and diet raw materials as components, is anticipated to achieve the effect of supplementing the nutrition, takes moringa oleifera as a main raw material, is processed by adopting a scientific and reasonable production process and has the advantages of definite function, controllable quality and safe taking. The preparation method of the effervescent granule, which is disclosed by the invention, is simple and completes the preparation through conventional equipment.

Description

A kind of drug regimen effervescence granular for supplementing the nutrients and preparation method thereof

Technical field

The invention belongs to health product technology field, relate to a kind of health products effervescence granular, particularly a kind of drug regimen effervescence granular for supplementing the nutrients and preparation method thereof.

Background technology

The expection of developing drugs combination product reaches the health care of extra-nutrition.This product is take Moringa as primary raw material, and is theoretical according to Traditional health care, adopts scientific and reasonable production technology to process, and this product function is clear and definite, and is quality controllable, takes safety.

Malnutrition is a term of describing health status, is caused by inappropriate or not enough diet.Be commonly referred to as and result from the subalimentation that insufficiency of intake, malabsorption or excessive loss's nutrient cause, but also may comprise owing to the overnutrition of eating and drinking immoderately or the excessive specific nutrient of absorption causes.If can not absorb for a long time the health diet that the nutrient by right quantity, kind or quality consists of, individuality will be experienced malnutritive.Malnutrition can cause that human body is old and feeble in early days, and hematopoiesis function is low, the synthetic difficulty of immune protein, organ-tissue MSOF, easier cancer stricken and various diseases.

Summary of the invention

Purpose of the present invention aims to provide for drug regimen effervescence granular that supplements the nutrients and preparation method thereof, this pharmaceutical composition is a kind of take the integration of drinking and medicinal herbs raw material as main medicine, this product is take Moringa as primary raw material, the nutriments such as a large amount of mineral matter, vitamin, amino acid are provided, reach the health care of extra-nutrition, take the crowd and can not produce dependence.

Technical scheme of the present invention is: design a kind of drug regimen effervescence granular for supplementing the nutrients, it is characterized in that composition and weight proportion thereof that it contains are: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates.

The preparation method of described a kind of drug regimen effervescence granular for supplementing the nutrients, it may further comprise the steps:

1) takes by weighing raw material by following weight ratio: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates;

2) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 8.6 parts of citric acids, is 65% ethanolic solution softwood processed with concentration;

3) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 11.4 parts of sodium acid carbonates, is 65% ethanolic solution softwood processed with concentration, and the 10-60 mesh sieve is granulated for subsequent use;

4) with step 2), 3) particle respectively 40-70 ℃ forced air drying 20-60 minute;

5) with the whole grain of particle 10-60 order in the step 4), add dolomol, mix

6) inner packing;

7) external packing, product inspection, warehouse-in.

Advantage of the present invention is: the primary raw material Moringa is a kind of typical tropical multi-functional plant among the present invention, long edible history is arranged, nutritious and comprehensive, ingestion standard every day that the content of several mineral materials, vitamin and essential amino acid in every 100g leaf powder is recommended than the World Health Organization (WHO) is high.Calcium in the Moringa, potassium, iron, etc. mineral matter abundant especially, calcium, iron, potassium content are respectively milk powder and analysis for soybean powder 3.49 times, 11.28 times, 3.92 times and 11.39 times, 1.67 times, 0.93 times in the 100g leaf of Moringa powder.Leaf of Moringa amyloid proteins matter and total dietary fiber content are higher, and fat content is on the low side, more meet modern people increase Macronutrient when reducing fat and energy demand.World council of church (Church World Service) has set up linked groups in a lot of countries, advocates the plantation Moringa, is intended to help the West Africa people by Moringa and resists malnutrition.Simultaneously, Moringa is more and more paid attention to for medical treatment and the health care of preventing and treating the diseases such as diabetes, hypertension, cardiovascular disease, obesity, skin disease, eye illness, hypoimmunity, scurvy, anaemia, rickets, depression, arthritis, rheumatism, calculus, digestive organs tumour.

This prescription not only can supplement the nutrients, and other diseases is had auxiliary therapeutic action, has good health care and attacks effect.It is theoretical that pharmaceutical composition of the present invention is used Traditional health care, take Moringa as primary raw material, provides the nutriments such as a large amount of mineral matter, vitamin, amino acid, reaches the health care of extra-nutrition.No dependence, safety, effectively.

The specific embodiment

The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.

Embodiment 1

A kind of drug regimen effervescence granular for supplementing the nutrients is characterized in that composition and weight proportion thereof that it contains are: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates.

The preparation method of described a kind of drug regimen effervescence granular for supplementing the nutrients, it may further comprise the steps:

1) takes by weighing raw material by following weight ratio: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates;

2) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 8.6 parts of citric acids, is 65% ethanolic solution softwood processed with concentration;

3) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 11.4 parts of sodium acid carbonates, is 65% ethanolic solution softwood processed with concentration, and the 10-60 mesh sieve is granulated for subsequent use;

4) with step 2), 3) particle respectively 40-70 ℃ forced air drying 20-60 minute;

5) with the whole grain of particle 10-60 order in the step 4), add dolomol, mix

6) inner packing;

7) external packing, product inspection, warehouse-in.

The Moringa extract is that known technology is not described in detail here.

The drug regimen effervescence granular that the embodiment of the invention 1 is used for supplementing the nutrients is treated underfed clinical observation

1 data and method

1.1 physical data

Malnutritive patient 100 examples that selection is received treatment voluntarily, male 72 examples, women 28 examples, 10 ~ 30 years old age, average 20 years old, the course of disease 1 month-1 year.Be divided at random treatment group 1, treatment group 2, each 25 example for the treatment of group 3 and control group, each is organized the patient age symptom and consists of without significant difference.Has comparativity (P〉0.05).

1.2 methods for the treatment of

The treatment group Primary Care is consistent, and control group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, a 5g.His chewable tablets of the auspicious bodyguard for the treatment of group 2 usefulness source multidimensional, one time 2, one day 1 time.The precious broken masson pine pollen for the treatment of group 3 usefulness states, 1/2 bag of every day.

2 results

2.1 curative effect determinate standard

Cure: whole body tiredness, tired unable, the lazy speech of breathing hard, the subjective symptoms such as hypologia and sign disappear, and face words arteries and veins is normal, and blood routine examination is every all normal; Take a turn for the better: subjective symptoms and sign obviously alleviate, and the anaemia sickly look is cured substantially, and it is normal that routine blood test is tending towards; Invalid: subjective symptoms thing significant change or increase the weight of.

The various symptom and signs of Chang Wuxiao anaemia are without changing or increasing the weight of

2.2 treatment results

?	Cure	Take a turn for the better	Invalid	Efficient
					Contrast	?	?	25	0
Treatment group 1	10	13	2	92%
					Treatment group 2	10	11	4	84%
Treatment group 3	8	13	4	84%

3 discuss

Nutritional deficiency is because the negative balance of Nutrition and Metabolism lacks one or more nutrients in the body, at first shows as the minimizing of in-vivo tissue nutrient content or concentration and descends, and chemical change and Functional change occur then, causes at last deficiency disease.Reason is more, comprise body to picked-up, the digestion of nutrient, absorb and utilize obstacle; Body increases the requirement of nutrient; Body is drained nutrient and is increased; The endotrophic element decomposes aggravation etc.The main cause as causing malnutrition take nutrient insufficiency of intake and malabsorption wherein.Especially body be in grow, when gestation, lactication and morbid state, to the increase in demand of nutrient, if the picked-up of nutrient is not enough, the easier malnutrition that causes.The preparation of employing take Moringa as primary raw material replenishes the nutriments such as a large amount of mineral matters, vitamin, amino acid, reaches the purpose of prevention, treatment, control.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.

Claims (2)

1. a drug regimen effervescence granular that is used for extra-nutrition is characterized in that composition and weight proportion thereof that it contains are: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates.

2. the preparation method of a kind of drug regimen effervescence granular for supplementing the nutrients according to claim 1, it may further comprise the steps:

1) takes by weighing raw material by following weight ratio: 20 parts of Moringa extracts, 40 parts of DEXTROSE ANHYDROUSs, 20 parts in sweet mellow wine, 8.6 parts of citric acids, 11.4 parts of sodium acid carbonates;

2) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 8.6 parts of citric acids, is 65% ethanolic solution softwood processed with concentration;

3) getting 10 parts of Moringa extracts, 20 parts of DEXTROSE ANHYDROUSs, 10 parts in sweet mellow wine, 11.4 parts of sodium acid carbonates, is 65% ethanolic solution softwood processed with concentration, and the 10-60 mesh sieve is granulated for subsequent use;

4) with step 2), 3) particle respectively 40-70 ℃ forced air drying 20-60 minute;

5) with the whole grain of particle 10-60 order in the step 4), add dolomol, mix;

6) inner packing;

7) external packing, product inspection, warehouse-in.