CN102961613B - 一种治疗小儿慢性荨麻疹的中药外洗液 - Google Patents
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Abstract
本发明公开了一种治疗小儿慢性荨麻疹的中药外洗液。祖国医学认为风邪为本病的主要病因，风热之邪客于肌表，引起营卫失调所致。为此，本发明选择具有疏风宣肺，清热凉血的中药山货榔、酸水草、大香附子、荨麻根、荆芥、玄参、白背三七、白鲜皮、小檗、牛蒡子、前胡、刺蒺藜、天麻、甘草，将上述中药放于砂锅内，加入清水适量，水煎成汁倒入容器内，待温度降至能耐受时用消毒棉纱布擦洗患处，每日一剂，早晚二次擦洗。经我院在104例患儿中临床试验，总有效率达到96.2％，明显优于对照组，而且省去了小儿口服药物的麻烦，副作用小。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗小儿慢性荨麻疹的中药外洗液。
背景技术
荨麻疹是皮肤科的常见病、多发病之一，荨麻疹不仅是成人的多发病，也是小儿多发病、常见病。小儿作为特殊群体，因其年龄不同，虽然同患荨麻疹，临床表现为局部或全身大小不等的局限性风疹块损害，骤然发生，迅速消退，也可以一天内数次发作，瘙痒剧烈，愈后不留痕迹，严重威胁儿童的健康。中药治疗该病有较好的疗效，由于小儿服药不易接受，将中药口服改为熏洗治疗，使用方便，经观察疗效满意，未发生不良反应。
发明内容
本发明的目的是提供一种治疗小儿慢性荨麻疹的中药外洗液。荨麻疹形态变化多端，故古代医书有各种不同的名称，如“瘾疹”、“风疹块”、“风疙瘩”等，祖国医学认为风邪为本病的主要病因，风有外风、内风，早在汉代，医家就认识到外风是在本病的主要原因。《金匮要略·水气病证论》中说“风气相搏，风强则为瘾疹”，故因禀赋不受，又食鱼虾等腥荤动风之物，或平素体虚卫表不固，复感风邪，郁于皮肤肌腠之间而发病；风热之邪客于肌表，引起营卫失调所致。因此临床治疗以疏风宣肺，清热凉血为法。
本发明的目的是通过以下技术方案实现的，该治疗小儿慢性荨麻疹的中药外洗液由以下重量份的中药制成：山货榔8-10份、酸水草7-9份、大香附子7-9份、荨麻根13-15份、荆芥9-11份、玄参7-9份、白背三七8-10份、白鲜皮5-7份、小檗5-7份、牛蒡子6-8份、前胡5-7份、刺蒺藜7-9份、天麻5-7份、甘草3-5份。
优选的，山货榔9份、酸水草8份、大香附子8份、荨麻根14份、荆芥10份、玄参8份、白背三七9份、白鲜皮6份、小檗6份、牛蒡子7份、前胡6份、刺蒺藜8份、天麻6份、甘草4份。
制备方法：将上述中药放于砂锅内，加入清水适量，浸泡30min，煮沸30min后，取汁备用。
方中：山货榔祛风消肿，舒筋活血；酸水草渗湿解表；大香附子祛风止痒；荨麻根祛风活血，止痛；荆芥发表散风，透疹消疮；玄参清热凉血，滋阴解毒；白背三七清热凉血，散瘀消肿；白鲜皮清热燥湿，祛风解毒；小檗清热燥湿，泻火解毒；牛蒡子疏散风热，透疹利咽，解毒消肿；前胡降气化痰，宣散风热；刺蒺藜平肝疏肝，祛风明目；天麻息风止痉，平抑肝阳，祛风通络；甘草益气补中，清热解毒，祛痰止咳，缓解止痛。
临床资料
1、一般资料104例患儿，随机分为治疗组和对照组，治疗组52例，男25例，女27例，年龄最大9岁，最小6个月，平均6.83岁；对照组52例，男24例，女28例，年龄最大8岁，最小5个月，平均5.95岁；临床特征为皮肤出现大小不等，形状不一的鲜红色或苍白色风团，出现的快、消退的也快，局部伴瘙痒或灼烧感，部分有发热，恶心呕吐，以风热型其辨证标准为皮色赤，奇痒难当，遇热则加剧，得冷则减轻；两组性别、年龄、病程等均无统计学差异，(P＞0.05)具有可比性。
2、诊断标准：根据中华医学会皮肤性病学分会制定的《荨麻疹诊疗指南(2007版)》的诊断标准：(1)风团大小不等，伴瘙痒，几乎每天发生；(2)风团反复发作，持续6周以上；(3)少数患者表现间歇性发作。
3、治疗方法治疗组使用上述中药煎汁外洗，将药汁倒入容器内，待温度降至能耐受时用消毒棉纱布擦洗患处，每日一剂，早晚二次擦洗。对照组口服司他斯汀片，＜8岁的患儿，1mg/次，1次/日；8岁～14岁，1mg/次，2次/日；两组均十天为一个疗程。
4、疗效标准根据每个患者治疗前和治疗后的症状总积分，按下列公式计算症状积分下降指数。SSRI＝(治疗前症状积分-治疗后症状积分)/治疗前症状积分。根据SSRI评价总体疗效。标准：①无效SSRI＜0.20；②有效SSRI0.20～＜0.60；③显效SSRI0.60～＜0.90；④治愈SSRI≥0.90。以显效和治愈的患者百分数为有效率。
5、治疗结果治疗组与对照组治疗两个疗程后疗效比较见表1。
表1治疗组与对照组治疗三个疗程后疗效比较[(例(％)]
注：两组总有效率相比，P，0.05两组差异有显著性。
具体是实施方式
实施例一：称取山货榔9g、酸水草8g、大香附子8g、荨麻根14g、荆芥10g、玄参8g、白背三七9g、白鲜皮6g、小檗6g、牛蒡子7g、前胡6g、刺蒺藜8g、天麻6g、甘草4g。使用方法：将药汁倒入容器内，待温度降至能耐受时用消毒棉纱布擦洗患处，每日一剂，早晚二次擦洗。
实施例二：称取山货榔8g、酸水草7g、大香附子7g、荨麻根13g、荆芥9g、玄参7g、白背三七8g、白鲜皮5g、小檗5g、牛蒡子6g、前胡5g、刺蒺藜7g、天麻5g、甘草3g。使用方法：将药汁倒入容器内，待温度降至能耐受时用消毒棉纱布擦洗患处，每日一剂，早晚二次擦洗。
实施例三：称取山货榔10g、酸水草9g、大香附子9g、荨麻根15g、荆芥11g、玄参9g、白背三七10g、白鲜皮7g、小檗7g、牛蒡子8g、前胡7g、刺蒺藜9g、天麻7g、甘草5g。使用方法：将药汁倒入容器内，待温度降至能耐受时用消毒棉纱布擦洗患处，每日一剂，早晚二次擦洗。
Claims (2)
1.一种治疗小儿慢性荨麻疹的中药外洗液，其特征在于该中药外洗液由以下重量份的中药制成：山货榔8-10份、酸水草7-9份、大香附子7-9份、荨麻根13-15份、荆芥9-11份、玄参7-9份、白背三七8-10份、白鲜皮5-7份、小檗5-7份、牛蒡子6-8份、前胡5-7份、刺蒺藜7-9份、天麻5-7份、甘草3-5份。
2.根据权利要求1所述的一种治疗小儿慢性荨麻疹的中药外洗液，其特征在于该中药外洗液由以下重量份的中药制成：山货榔9份、酸水草8份、大香附子8份、荨麻根14份、荆芥10份、玄参8份、白背三七9份、白鲜皮6份、小檗6份、牛蒡子7份、前胡6份、刺蒺藜8份、天麻6份、甘草4份。
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| CN103751462A (zh) * | 2014-02-08 | 2014-04-30 | 刘方荣 | 一种治疗风热血燥型脂溢性皮炎的中药酊剂 |
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