CN102941034A - Medical humidification liquid having bacteriostasis function - Google Patents
Medical humidification liquid having bacteriostasis function Download PDFInfo
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- CN102941034A CN102941034A CN2011103665234A CN201110366523A CN102941034A CN 102941034 A CN102941034 A CN 102941034A CN 2011103665234 A CN2011103665234 A CN 2011103665234A CN 201110366523 A CN201110366523 A CN 201110366523A CN 102941034 A CN102941034 A CN 102941034A
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Abstract
The invention discloses a medical humidification liquid having a bacteriostasis function and relates to the medical field. The medical humidification liquid having a bacteriostasis function comprises epsilon-polylysine and distilled water, wherein 0.01 to 0.5g of epsilon-polylysine is added into each 100ml of distilled water. The medical humidification liquid having a bacteriostasis function also comprises a bacteriostatic agent which is sodium chloride, citric acid, glycine, acetic acid, alcohol or tea polyphenol. The medical humidification liquid having a bacteriostasis function is a safe and efficient reagent having no toxic and side effects and has good effects in oxygen humidification and clinical care. The medical humidification liquid having a bacteriostasis function has a simple formula and a low price, can be preserved easily, can kill and inhibit pathogenic bacteria and conditioned pathogens in an oxygen humidification liquid, has low replacement frequency, has good effects of disinfection and humidification, provides a comfortable patient oxygen inhalation environment after humidification, and improves clinical care work efficiency.
Description
Technical field
The present invention relates to medical field, be specifically related to have in a kind of clinical care use the medical humidification fluid of bacteria resistance function.
Background technology
In medical field, oxygen therapy is the most frequently used clinically a kind of nursing technique and rescue means.Because each normal organ of human body has the gentle humidifying effect that adds to sucking gas, gas when a large amount of suction humidifying deficiencies, easily cause the air flue mucosa injury, ciliary movement is obstructed, the phlegm scab is blocked, and the pulmonary infection rate also raises along with the reduction of air flue humidification degree, therefore, in process of oxygen therapy, generally all need adopt oxygen humidifying liquid that oxygen is carried out humidifying, to improve oxygen therapy effect and patient's comfort level.Widely used medical humidification fluid is distilled water clinically at present, there are some researches show, when adopting distilled water to use as humidification fluid, humidification fluid microbial contamination is quite general, and pollution rate is up to 89.6%, and the severe contamination person accounts for 37.1%, bacterium easily grows in the oxygen suction humidifying bottle, and along with the prolongation of service time, microorganism recall rate and severe contamination person all obviously increase, and easily cause the problem of respiratory tract scabies secondary infection.
Summary of the invention
The objective of the invention is for top described defective, the medical humidification fluid that has bacteria resistance function in a kind of clinical care use is provided.
The objective of the invention is to be achieved by the following technical programs.
A kind of medical humidification fluid with bacteria resistance function comprises epsilon-polylysine and distilled water, wherein, contains the 0.01-0.5g epsilon-polylysine in every 1000ml distilled water.
A kind of medical humidification fluid with bacteria resistance function also comprises bacteriostatic agent, and described bacteriostatic agent is a kind of in sodium chloride, citric acid, glycine, acetic acid, alcohol or the Tea Polyphenols.
The pH value of described medical humidification fluid is 5.0-8.0.
Sodium chloride-containing 0.1-3g in every 1000ml medical humidification fluid.
Contain citric acid 0.01-0.5g in every 1000ml medical humidification fluid.
Contain glycine 0.01-10g in every 1000ml medical humidification fluid.
Contain acetic acid 0.01-0.5g in every 1000ml medical humidification fluid.
Spirituosity 300-700ml in every 1000ml medical humidification fluid.
Contain Tea Polyphenols 0.01-0.3g in every 1000ml medical humidification fluid.
The invention has the beneficial effects as follows: the present invention adds epsilon-polylysine and other bacteriostatic agent in distilled water, epsilon-polylysine is a kind of polypeptide with bacteriostasis efficacy, and hygroscopicity is strong, can be decomposed into lysine in human body.The epsilon-polylysine antimicrobial spectrum is wide, for sharp-pointed candidiasis, method Rhodotorula sp, product film pichia yeast, the rose shadow yeast of saccharomyces; Heat-resisting fatty bacillus in the gram-positive bacteria, bacillus coagulans, bacillus subtilis; Aerogenesis arthrobacterium in the Gram-negative bacteria, Escherichia coli etc. have obvious inhibition and killing action.To gram-positive micrococcus luteus, lactobacillus bulgaricus, hot streptococcus, gram-negative Escherichia coli, salmonella and saccharomycetic growth have obvious inhibition.Epsilon-polylysine and acetic acid, citric acid share has obvious inhibitory action to bacillus subtilis; Wherein a kind of to share fungistatic effect more obvious than using separately with glycine, Tea Polyphenols, sodium chloride; Share with alcohol also has obvious inhibitory action to budding fungus, and different bacteriostatic agents can be selected according to different crowds.And the epsilon-polylysine heat endurance is high, can together carry out sterilization treatment with solvent, is a kind of safe, efficient, reagent of having no side effect, and it is respond well to be used for oxygen humidification and clinical care.Pathogenic bacteria and conditioned pathogen in the oxygen humidifying liquid can be killed, be suppressed to simple, cheap, easy preservation that the present invention disposes, and it is few to change number of times, can play good sterilization, moistening purpose; Comfort level in the time of can providing patient's oxygen uptake after the process humidifying simultaneously, and can improve clinical nursing activity efficient.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1.
Preparation 1000ml medical humidification fluid of the present invention is used for clinical care and uses: comprises 1000ml distilled water and 0.05g epsilon-polylysine, require humidification fluid aseptic.
Embodiment 2.
1. precision takes by weighing epsilon-polylysine 0.05g and puts into that to be mixed with mother liquor in the 100ml distilled water stand-by.
2. the epsilon-polylysine mother liquor for preparing is replenished distilled water to 1000ml, stir, regulate pH value between the 5.0-8.0.
3. can, sealing, 115 ℃ of high-temperature heat sterilizations 30 minutes.
4. detect deposit after qualified for subsequent use.
Embodiment 3.
Preparation 1000ml medical humidification fluid of the present invention is used for clinical care and uses: comprise 1000ml distilled water, 0.08g epsilon-polylysine and 1.5g sodium chloride, regulate pH value between the 5.0-8.0, require humidification fluid aseptic.
Embodiment 4.
Preparation 1000ml medical humidification fluid of the present invention, being used for the clinical care oxygen humidification uses: comprise 1000ml distilled water, 0.3g epsilon-polylysine and 0.05g glycine, regulate pH value between the 5.0-8.0, the requirement humidification fluid is aqua sterilisa, total number of bacterial colonies is answered≤20cmu/ml, and pathogenic bacteria must not detect.Detecting qualified rear can deposits for subsequent use.
Embodiment 5.
Preparation 1000ml medical humidification fluid of the present invention, being used for the clinical care oxygen humidification uses: comprise 1000ml distilled water, 0.1g epsilon-polylysine and 0.2g citric acid, regulate pH value between the 5.0-8.0, the requirement humidification fluid is aqua sterilisa, total number of bacterial colonies is answered≤20cmu/ml, and pathogenic bacteria must not detect.
Embodiment 6.
Preparation 1000ml medical humidification fluid of the present invention, being used for the clinical care oxygen humidification uses: comprise 1000ml distilled water, 0.2g epsilon-polylysine and 0.2g acetic acid, regulate pH value between the 5.0-8.0, the requirement humidification fluid is aqua sterilisa, total number of bacterial colonies is answered≤20cmu/ml, and pathogenic bacteria must not detect.
Embodiment 7.
Preparation 1000ml medical humidification fluid of the present invention, being used for the clinical care oxygen humidification uses: comprise 1000ml distilled water, 0.04g epsilon-polylysine and 0.08g Tea Polyphenols, regulate pH value between the 5.0-8.0, the requirement humidification fluid is aqua sterilisa, total number of bacterial colonies is answered≤20cmu/ml, and pathogenic bacteria must not detect.
Above content is the further description of the present invention being done in conjunction with concrete preferred embodiment, can not assert that implementation of the present invention is confined to these explanations.For the general technical staff of the technical field of the invention, make without departing from the inventive concept of the premise some substituting or obvious modification, and performance or purposes are identical, all should be considered as belonging to protection scope of the present invention.
Claims (9)
1. the medical humidification fluid with bacteria resistance function comprises epsilon-polylysine and distilled water, it is characterized in that: contain the 0.01-0.5g epsilon-polylysine in every 1000ml distilled water.
2. a kind of medical humidification fluid with bacteria resistance function according to claim 1 is characterized in that: also comprise bacteriostatic agent, described bacteriostatic agent is a kind of in sodium chloride, citric acid, glycine, acetic acid, alcohol or the Tea Polyphenols.
3. a kind of medical humidification fluid with bacteria resistance function according to claim 1 and 2, it is characterized in that: the pH value of described medical humidification fluid is 5.0-8.0.
4. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: sodium chloride-containing 0.1-3g in every 1000ml medical humidification fluid.
5. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: contain citric acid 0.01-0.5g in every 1000ml medical humidification fluid.
6. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: contain glycine 0.01-10g in every 1000ml medical humidification fluid.
7. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: contain acetic acid 0.01-0.5g in every 1000ml medical humidification fluid.
8. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: spirituosity 300-700ml in every 1000ml medical humidification fluid.
9. a kind of medical humidification fluid with bacteria resistance function according to claim 2 is characterized in that: contain Tea Polyphenols 0.01-0.3g in every 1000ml medical humidification fluid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011103665234A CN102941034A (en) | 2011-11-18 | 2011-11-18 | Medical humidification liquid having bacteriostasis function |
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| Application Number | Priority Date | Filing Date | Title |
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| CN2011103665234A CN102941034A (en) | 2011-11-18 | 2011-11-18 | Medical humidification liquid having bacteriostasis function |
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| CN102941034A true CN102941034A (en) | 2013-02-27 |
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| CN2011103665234A Pending CN102941034A (en) | 2011-11-18 | 2011-11-18 | Medical humidification liquid having bacteriostasis function |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103990414A (en) * | 2014-05-27 | 2014-08-20 | 浙江康德药业集团有限公司 | Oxygen humidifying solution with bacteriostasis function and preparation method thereof |
| CN104472541A (en) * | 2014-12-10 | 2015-04-01 | 杭州美泰医疗器械有限公司 | Oxygen humidifying fluid bacteriostatic agent |
| CN111838176A (en) * | 2020-08-05 | 2020-10-30 | 江苏中新瑞光学材料有限公司 | Oxygen humidifying liquid bacteriostatic agent |
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| CN101658705A (en) * | 2009-04-23 | 2010-03-03 | 陈旭良 | Medical humidification fluid with bacteria resistance function |
| CN101690836A (en) * | 2009-10-15 | 2010-04-07 | 石家庄诺利达医疗器械有限公司 | Oxygen humidifying liquid |
| CN102028705A (en) * | 2010-11-01 | 2011-04-27 | 西藏贝珠雅药业有限公司 | Gynecologic article containing biological antifungal components |
| CN102188034A (en) * | 2010-03-03 | 2011-09-21 | 天津科技大学 | Compound biological antiseptic and preservation agent for food |
| CN102389743A (en) * | 2011-06-14 | 2012-03-28 | 陈旭良 | Formula of medical bacteriostatic humidifying solution |
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2011
- 2011-11-18 CN CN2011103665234A patent/CN102941034A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101658705A (en) * | 2009-04-23 | 2010-03-03 | 陈旭良 | Medical humidification fluid with bacteria resistance function |
| CN101690836A (en) * | 2009-10-15 | 2010-04-07 | 石家庄诺利达医疗器械有限公司 | Oxygen humidifying liquid |
| CN102188034A (en) * | 2010-03-03 | 2011-09-21 | 天津科技大学 | Compound biological antiseptic and preservation agent for food |
| CN102028705A (en) * | 2010-11-01 | 2011-04-27 | 西藏贝珠雅药业有限公司 | Gynecologic article containing biological antifungal components |
| CN102389743A (en) * | 2011-06-14 | 2012-03-28 | 陈旭良 | Formula of medical bacteriostatic humidifying solution |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103990414A (en) * | 2014-05-27 | 2014-08-20 | 浙江康德药业集团有限公司 | Oxygen humidifying solution with bacteriostasis function and preparation method thereof |
| CN104472541A (en) * | 2014-12-10 | 2015-04-01 | 杭州美泰医疗器械有限公司 | Oxygen humidifying fluid bacteriostatic agent |
| CN111838176A (en) * | 2020-08-05 | 2020-10-30 | 江苏中新瑞光学材料有限公司 | Oxygen humidifying liquid bacteriostatic agent |
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Application publication date: 20130227 |