CN102940765A - Medicine for treating breast cancer and preparation method of medicine - Google Patents

Medicine for treating breast cancer and preparation method of medicine Download PDF

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CN102940765A
CN102940765A CN2012104974884A CN201210497488A CN102940765A CN 102940765 A CN102940765 A CN 102940765A CN 2012104974884 A CN2012104974884 A CN 2012104974884A CN 201210497488 A CN201210497488 A CN 201210497488A CN 102940765 A CN102940765 A CN 102940765A
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CN102940765B (en
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闫位国
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Guangxi Dongxing City Innovation Characteristic Medical Science & Technology Development Co Ltd
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Abstract

The invention discloses a medicine for treating breast cancer and a preparation method of the medicine. The medicine comprises a medicine A and a medicine B, wherein the medicine A comprises croton, dragon's blood, realgar and bee wax in compatibility and is prepared by hulling the croton, wrapping the croton with the bee wax and then mixing the croton with the dragon's blood and realgar powder, and the medicine B comprises Chinese medicines including pangolin, Teloon, scorpio, centipede, pearl, processed semen strychni, dried bodies of ground beeltle, bupleurum, skunk bugbane, asarum, ephedra, monkshood, cinnamon, oyster, platycodon and rheum in compatibility. The Chinese medicines are extracted by being crushed or decocted with water to prepare thick paste, and an appropriate number of auxiliary materials are added to prepare different preparations. The medicine has the functions of suppressing tumor, removing stagnation, promoting blood circulation, removing blood stasis and activating meridians to stop pain, the immunity of a patient can be improved, cancer cells are stopped from spreading, the functions of reducing toxicity and enhancing efficacy are achieved for radiation therapy and chemical therapy, the condition of the patient can be controlled, the pain can be relieved, the life quality of the patient is improved, symptoms can be attenuated in medicine taking period, and the pure Chinese medicine preparations have no toxic and side effects.

Description

A kind of medicine for the treatment of breast carcinoma and preparation method thereof
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of medicine for the treatment of breast carcinoma and preparation method thereof.
Background technology
Breast carcinoma is a kind of common disease, is mainly in middle-aged women, and breast carcinoma is most for forming the day after tomorrow.Have traditional Chinese medical science scholar to think that the cause of disease of breast carcinoma has three: one, wind-cold damp pathogen is invaded body, and cold-damp is condensed and caused dys-splenism, and yang-energy can not lifting, and expectorant is from interior life, and is strongly fragrant and fire-transformation forms lump; The 2nd, have a liking for well the dry product of pungent perfume (or spice), impairing the spleen and stomach causes giving birth in the phlegm-fire, and phlegm-damp condenses, and forms lump; The 3rd, feelings will is hindered, depression of liver-QI, and qi depression to blood stasis, mechanism of qi is obstructed, and irritability can not catharsis, and lump condenses.
The Chinese medicine of existing treatment breast carcinoma is more, and unguentum or peroral tablets etc. are arranged, and also has their own characteristics each in treatment, but yet there are no the open report that the application organizes the medicine of stating combination matching.
Summary of the invention
The technical problem to be solved in the present invention provides a kind of instant effect, medicine of the treatment breast carcinoma that therapeutic effect is good and preparation method thereof.
Technical scheme provided by the invention is a kind of medicine for the treatment of breast carcinoma, and it is comprised of the separate medicine A that separately takes and medicine B;
Medicine A comprises that the raw material of following weight portion makes: 50~100 parts of Fructus Crotonis, 2~10 parts of Sanguis Draxonis, 2~10 parts of Realgars, 50~100 parts in Cera Flava;
Medicine B comprises that the raw material of following weight portion makes: 50~100 parts of Squama Maniss, 50~100 parts of Gekko Swinhonis, 10~20 parts of Scorpios, 10~20 parts of Scolopendras, 10~50 parts of eupolyphaga, 50~100 parts of Radix Bupleuri, 20~50 parts of Rhizoma Cimicifugaes, 20~50 parts of Herba Asaris, 100~200 parts of Radix Aconiti Lateralis Preparatas, 20~50 parts in Herba Ephedrae, 20~50 parts of Bulbus Fritillariae Thunbergii, 100~200 parts of Concha Ostreaes, 20~50 parts of Radix Platycodoniss, 10~20 parts of Radix Et Rhizoma Rhei, 10~20 parts of Semen Strychni (processed)s, 10~20 parts of Cortex Cinnamomis.
The weight portion of this each raw material of medicine is: 75 parts of Fructus Crotonis, 6 parts of Sanguis Draxonis, 8 parts of Realgars, 75 parts in Cera Flava, 80 parts of Squama Maniss, 80 parts of Gekko Swinhonis, 15 parts of Scorpios, 17 parts of Scolopendras, 30 parts of eupolyphaga, 75 parts of Radix Bupleuri, 40 parts of Rhizoma Cimicifugaes, 35 parts of Herba Asaris, 150 parts of Radix Aconiti Lateralis Preparatas, 35 parts in Herba Ephedrae, 40 parts of Bulbus Fritillariae Thunbergii, 150 parts of Concha Ostreaes, 35 parts of Radix Platycodoniss, 15 parts of Radix Et Rhizoma Rhei, 15 parts of Semen Strychni (processed)s, 15 parts of Cortex Cinnamomis.
The present invention also provides the preparation method of the medicine of above-mentioned treatment breast carcinoma, comprises the preparation method of medicine A and medicine B;
Wherein, the preparation method of medicine A may further comprise the steps:
1) take by weighing each raw material of medicine A by prescription, for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form fine powder, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 5~7 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A;
The preparation method of medicine B may further comprise the steps:
1) take by weighing each raw material of medicine B by prescription, for subsequent use;
2) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the fine powder for subsequent use;
3) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, merges decoction liquor, and the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.20~1.30 thick paste at 60 ℃;
4) with step 2) medicated powder and step 3) the thick paste mixing, make as required different preparations, be medicine B.
The step 3 of the preparation method of medicine A) granularity of fine powder described in is 100~300 orders, the step 2 of the preparation method of medicine B) described in the granularity of fine powder be 100~300 orders.
The step 3 of the preparation method of medicine B) in, in decocting with water process, for the first time the consumption of water is 8~12 times of drug weight, decocts 1~3 hour, and the second time, the consumption of water was 6~10 times of drug weight, decocted 1~3 hour.
The step 4 of the preparation method of medicine B) in, the dosage form of medicine B is tablet, granule or capsule.To those skilled in the art, according to the dosage form needs, select conventional pharmaceutical necessities to make suitable medicament, belong to conventional, general technology.
Instructions of taking: medicine A and medicine B separately take, and medicine A takes 3 times every day, each 4~5, send down with cold boiled water.Medicine B takes 3 times every day, a 6g, and warm water takes.
The mechanism of each raw medicinal material is as follows in the medicine of the present invention:
Fructus Crotonis, hot in nature, bitter in the mouth enters spleen, stomach, large intestine three warps, rushing down cold long-pending, orifice opening, by expectorant,, row water, parasite killing; Sanguis Draxonis, sweet in the mouth, salty, property is flat, enters the heart, liver, spleen channel, promoting blood circulation to remove blood stasis, analgesic therapy, hemostasia and promoting granulation; Realgar, acrid in the mouth, warm in nature is returned liver, large intestine channel, detoxifcation parasite killing, removing dampness and eliminating phlegm, preventing the attack (or recurrence) of malaria; Cera Flava, sweet in the mouth, slightly warm in nature, astringent therapy, sore, granulation promoting, pain relieving, conditioning; Squama Manis, salty in the mouth, cold nature enter liver, stomach warp, and blood circulation promoting and dispersing pathogen accumulation, the stimulating milk secretion of stimulating the menstrual flow, eliminating carbuncle are burst hard; Gekko Swinhonis is the dry products of Gekko Swinhonis, and salty in the mouth, cold in nature is returned Liver Channel, expelling wind for relieving convulsion, detoxicating and resolving stagnation of pathogens; Scorpio, acrid in the mouth, property are put down, and return Liver Channel, the spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain; Scolopendra, warm in nature, acrid in the mouth, endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain; Eupolyphaga, salty in the mouth, cold in nature is returned Liver Channel, lower blood stasis, eliminating mass abdominal mass; Radix Bupleuri, cold nature, bitter in the mouth, suffering are returned Liver Channel, lung meridian, spleen channel, and expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Rhizoma Cimicifugae, acrid in the mouth, little sweet, cold nature is returned lung, spleen, stomach, large intestine channel, delivers rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy; Herba Asari, acrid in the mouth, warm in nature enters lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel, the cold expelling that induces sweat, wind-expelling pain-stopping; Radix Aconiti Lateralis Preparata, acrid in the mouth, sweet, hot in nature, GUIXIN, kidney, spleen channel, recuperating depleted YANG and rescuing the patient from collapse, supporing yang, the dispersing cold for relieving pain of benefit fire; Herba Ephedrae, acrid in the mouth, little hardship, warm in nature, return lung, urinary bladder channel, diaphoresis cold expelling, depressed lung-energy dispersing, inducing diuresis to remove edema; Semen Strychni (processed), bitter in the mouth, cold in nature is returned liver, spleen two warps, removing obstruction in the collateral to relieve pain, dispersing swelling and dissipating binds; Concha Ostreae, salty in the mouth, cold nature is returned liver, gallbladder, kidney channel, suppressing the hyperactive liver to relieve the wind syndrome, yin nourishing; Radix Platycodonis, bitter in the mouth, suffering, slightly warm in nature enters lung meridian, lung qi dispersing, eliminates the phlegm, sore-throat relieving, evacuation of pus, sharp the five internal organs, fills blood, mends five kinds of over strain, fosters the spirit of nobility.Radix Et Rhizoma Rhei, bitter in the mouth, cold in nature, enter stomach warp, large intestine channel, Liver Channel, spleen channel, attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, detoxifcation; Bulbus Fritillariae Thunbergii, cold in nature, bitter in the mouth, removing heat-phlegm, dissipating depression of QI eliminating stagnation; Cortex Cinnamomi, extremely hot in nature, acrid in the mouth, sweet is returned kidney, spleen, the heart, Liver Channel, mends fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.
The medicine that said herbal medicine is made by formula compatibility of the present invention has the effect of tumor suppression eliminating stagnation, blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain, treatment breast carcinoma successful, treating both the principal and secondary aspects of a disease improves patient's digestive tract function in the growth of anticancer and transfer, improve immunity, stop the cancerous cell diffusion, Radiotherapy chemotherapy is played the effect of attenuation synergistic, can control the state of an illness, palliate the agonizing sufferings, improve life in patients, can be in medication period mitigation symptoms, and pure Chinese medicinal preparation has no side effect.
The specific embodiment:
The invention will be further described with specific embodiment, but the present invention is not limited to these embodiment.
Embodiment 1
1) proportioning by embodiment 1 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form 100 purpose fine powders, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 5 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A, one day 3 times, 1 time 4~5, send down with cold boiled water;
5) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the 100 purpose fine powders for subsequent use;
6) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, in decocting with water process, for the first time the consumption of water is 8 times of drug weight, decocts 1 hour, and the second time, the consumption of water was 6 times of drug weight, decocted 1 hour, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.20 thick paste at 60 ℃;
7) with step 5) medicated powder and step 6) the thick paste mixing, the starch mixing that adds routine dose, granulate, sieve, dry, granulate, incapsulate, be medicine B (capsule), every dress 0.3g, half an hour ante cibum is oral, warm water send down, one time 20, one month is a course for the treatment of.
Embodiment 2
1) proportioning by embodiment 2 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form 300 purpose fine powders, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 7 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A, one day 3 times, 1 time 4~5, send down with cold boiled water;
5) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the 300 purpose fine powders for subsequent use;
6) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, in decocting with water process, for the first time the consumption of water is 12 times of drug weight, decocts 3 hours, and the second time, the consumption of water was 10 times of drug weight, decocted 3 hours, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.30 thick paste at 60 ℃;
7) with step 5) medicated powder and step 6) the thick paste mixing, add dextrin and sweeting agent, drying, granulation, granulate pack and are medicine B (granule).Usually half an hour ante cibum warm boiled water, one time 1 bag, one bag of 6g, 3 times on the one, one month is a course for the treatment of.
Embodiment 3
1) proportioning by embodiment 3 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form 200 purpose fine powders, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 6 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A, one day 3 times, 1 time 4~5, send down with cold boiled water;
5) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the 200 purpose fine powders for subsequent use;
6) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, in decocting with water process, for the first time the consumption of water is 10 times of drug weight, decocts 2 hours, and the second time, the consumption of water was 8 times of drug weight, decocted 2 hours, merge decoction liquor, the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.25 thick paste at 60 ℃;
7) with step 5) medicated powder and step 6) the thick paste mixing, pulverize, granulate, compacting is medicine B (tablet) in flakes.Usually half an hour ante cibum warm water delivery service, each serving using 6g, every day three times, 30 is a course for the treatment of.
Embodiment 4
1) proportioning by embodiment 4 in the following table 1 takes by weighing each raw material, and is for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form 100 purpose fine powders, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 7 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A, one day 3 times, 1 time 4~5, send down with cold boiled water;
5) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the 100 purpose fine powders for subsequent use;
6) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, in decocting with water process, for the first time the consumption of water is 12 times of drug weight, decocted 1 hour, for the second time the consumption of water is 10 times of drug weight, decocts the merging decoction liquor 1 hour, the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.30 thick paste at 60 ℃;
7) with step 5) medicated powder and step 6) the thick paste mixing, add dextrin and sweeting agent, drying, granulation, granulate pack and are medicine B (granule).Usually half an hour ante cibum warm boiled water, one time 1 bag, one bag of 6g, 3 times on the one, one month is a course for the treatment of.
Table 1
Raw material (g) Embodiment 1 Embodiment 2 Embodiment 3 Embodiment 4
Fructus Crotonis 50 100 75 50
Sanguis Draxonis 2 10 6 10
Realgar 2 10 8 2
Cera Flava 50 100 75 100
Squama Manis 50 100 80 50
Gekko Swinhonis 50 100 80 100
Scorpio 10 20 15 10
Scolopendra 10 20 17 20
Eupolyphaga 10 50 30 10
Radix Bupleuri 50 100 75 100
Rhizoma Cimicifugae 20 50 40 20
Herba Asari 20 50 35 50
Radix Aconiti Lateralis Preparata 100 200 150 100
Herba Ephedrae 20 50 35 50
Bulbus Fritillariae Thunbergii 20 50 40 20
Concha Ostreae 100 200 150 200
Radix Platycodonis 20 50 35 20
Radix Et Rhizoma Rhei 10 20 15 20
Semen Strychni (processed) 10 20 15 10
Cortex Cinnamomi 10 20 15 20
Use and the therapeutic effect of medicine of the present invention are described below in conjunction with concrete case.
Case 1: Chen Qilin, the woman, 53 years old, because the left side mammary gland tumor increased the weight of in more than 2 years days then, shifted through being diagnosed as the breast carcinoma many places in April, 2006, the bilateral breast lump, the oxter lump, Bilateral Cervical and head many places lump are taken the medicine 3 months of the embodiment of the invention 1 on May 17th, 2006, transference cure is followed up a case by regular visits to and was had no recurrence in 2 years.
Case 2: Huang Ermei, the woman, 32 years old, because left side mammary gland swelled more than 1 year, day satisfy enlargement, matter is hard, in Mays 12 in 2007 the Nikkei hospital diagnosis be the pernicious muscular tumor of left side mammary gland, take the medicine 2 months of the embodiment of the invention 2 on May 19th, 2007, transference cure is followed up a case by regular visits to and is had no recurrence.
Case 3: Li Xiulan, woman, 40 years old, bilateral breast lump, matter is hard, tenderness, and mobility is poor, is the bilateral breast malignant tumor in April, 2008 through hospital diagnosis, multi-treatment has no improvement, the medicine of taking the embodiment of the invention 3 on July 11st, 2008 transference cure after 3 months, recurrence that so far there are no.
Case 4: the summer is beautiful, the woman, 42 years old, the patient was breast carcinoma late period at hospital diagnosis the year before, has then done the mammary cancer radical operation operation, and carry out chemotherapeutic treatment, not good because of chemotherapy effect, side effect is large, and the patient can't continue chemotherapy, cancer cell metastasis before half a year, hydrothorax, hospital announces can only to survive two months, after use Chinese traditional treatment instead, Drug therapy through taking the embodiment of the invention 4 is after two courses for the treatment of, body constitution is clearly better, and hydrothorax disappears substantially, continues to take a course for the treatment of, all transference cures, spiritual diet is normal.
Case 5: Rhizoma Picrorhizae side, the woman, 60 years old, mammary swelling had pain, and it is breast carcinoma that the image irradiation has lump, hospital diagnosis.The medicine of taking the embodiment of the invention 1 in October, 2010 is after 1 month, swelling sense hour, take 3 months continuously after, the lump complete obiteration, through hospital diagnosis, indices is normal.
Case 6: Zhou Daqin, woman, 64 years old, the patient checks in January, 2009 and finds that right breast has a lump, matter is hard, after feel distending pain of the breast, be diagnosed as cyclomastopathy, rear use antibiotic therapy is invalid, to increase to 5cm large for lump speed subsequently, and what push away does not move, and do not press from pain, and axil and sternocostal part radiation to the right, be diagnosed as breast carcinoma in August, 2010.The medicine that begins subsequently to take the embodiment of the invention 2 is after 3 months, and mastalgia subtracts greatly, and lump obviously diminishes, and spirit takes a turn for the better, and after continuing to take 3 months, lump disappears, and body weight increases.The recurrence of following up a case by regular visits to that so far there are no.
Case 7: Zhao Xiaowen, the woman, 55 years old, the patient checked in April, 2011 and finds that left breast has 2 of 2cm lumps, is diagnosed as the left breast cancer II phase.Patient's lassitude, shallow complexion, inappetence, insufficiency of the spleen, phlegm-damp is not changed.Take subsequently the medicine of the embodiment of the invention 3 after 2 months, mastalgia subtracts greatly, and lump reduces, and spirit takes a turn for the better, and continues to take 1 month, and lump has disappeared most, and matter is soft, and the patient got well when paid a return visit in March, 2012, was as good as with ordinary person.
Case 8: Fang Xia, the woman, 60 years old, the patient was diagnosed as right breast carcinoma in March, 2009, and implemented right newborn resection operation.The medicine that begins to take the embodiment of the invention 4 in June, 2009 is after 3 months, and body weight increases, and body constitution strengthens, and finds through check, and tumor and cancerous cell complete obiteration return to one's perfect health.

Claims (6)

1. medicine for the treatment of breast carcinoma, its thing is levied and is: it is comprised of the separate medicine A that separately takes and medicine B;
Medicine A comprises that the raw material of following weight portion makes: 50~100 parts of Fructus Crotonis, 2~10 parts of Sanguis Draxonis, 2~10 parts of Realgars, 50~100 parts in Cera Flava;
Medicine B comprises that the raw material of following weight portion makes: 50~100 parts of Squama Maniss, 50~100 parts of Gekko Swinhonis, 10~20 parts of Scorpios, 10~20 parts of Scolopendras, 10~50 parts of eupolyphaga, 50~100 parts of Radix Bupleuri, 20~50 parts of Rhizoma Cimicifugaes, 20~50 parts of Herba Asaris, 100~200 parts of Radix Aconiti Lateralis Preparatas, 20~50 parts in Herba Ephedrae, 20~50 parts of Bulbus Fritillariae Thunbergii, 100~200 parts of Concha Ostreaes, 20~50 parts of Radix Platycodoniss, 10~20 parts of Radix Et Rhizoma Rhei, 10~20 parts of Semen Strychni (processed)s, 10~20 parts of Cortex Cinnamomis.
2. the medicine for the treatment of breast carcinoma according to claim 1, it is characterized in that: the weight portion of each raw material is: 75 parts of Fructus Crotonis, 6 parts of Sanguis Draxonis, 8 parts of Realgars, 75 parts in Cera Flava, 80 parts of Squama Maniss, 80 parts of Gekko Swinhonis, 15 parts of Scorpios, 17 parts of Scolopendras, 30 parts of eupolyphaga, 75 parts of Radix Bupleuri, 40 parts of Rhizoma Cimicifugaes, 35 parts of Herba Asaris, 150 parts of Radix Aconiti Lateralis Preparatas, 35 parts in Herba Ephedrae, 40 parts of Bulbus Fritillariae Thunbergii, 150 parts of Concha Ostreaes, 35 parts of Radix Platycodoniss, 15 parts of Radix Et Rhizoma Rhei, 15 parts of Semen Strychni (processed)s, 15 parts of Cortex Cinnamomis.
3. the preparation method of the medicine for the treatment of breast carcinoma claimed in claim 1 is characterized in that: the preparation method that comprises medicine A and medicine B;
Wherein, the preparation method of medicine A may further comprise the steps:
1) take by weighing each raw material of medicine A by prescription, for subsequent use;
2) get Fructus Crotonis and shell and get the Semen Coicis granulate, for subsequent use;
3) Realgar, Sanguis Draxonis are ground to form fine powder, for subsequent use;
4) Cera Flava is fried in shallow oil to getting away, step 2) Fructus Crotonis rice place Cera Flava to take out after 5~7 minutes at a simmer, be filtered dry Cera Flava, instant blend step 3) Realgar powder and Sanguis Draxonis powder, dry, sterilization gets medicine A;
The preparation method of medicine B may further comprise the steps:
1) take by weighing each raw material of medicine B by prescription, for subsequent use;
2) getting Squama Manis, Gekko Swinhonis, Scorpio, Scolopendra, Bulbus Fritillariae Thunbergii and Semen Strychni (processed) cleans, dries, grinds to form behind the fine powder for subsequent use;
3) fetch earth unit, Radix Bupleuri, Rhizoma Cimicifugae, Herba Asari, Herba Ephedrae, Radix Aconiti Lateralis Preparata, Cortex Cinnamomi, Concha Ostreae, Radix Platycodonis, Radix Et Rhizoma Rhei selects materials to clean and decocts with water 2 times, merges decoction liquor, and the elimination medicinal residues are got filtrate and are condensed into relative density and are determined as 1.20~1.30 thick paste at 60 ℃;
4) with step 2) medicated powder and step 3) the thick paste mixing, make as required different preparations, be medicine B.
4. the preparation method of the medicine for the treatment of breast carcinoma according to claim 3 is characterized in that: the step 3 of the preparation method of medicine A) and the step 2 of the preparation method of medicine B) in, the granularity of described fine powder is 100~300 orders.
5. the preparation method of the medicine for the treatment of breast carcinoma according to claim 3, it is characterized in that: the step 3 of the preparation method of medicine B), in decocting with water process, for the first time the consumption of water is 8~12 times of drug weight, decocted 1~3 hour, for the second time the consumption of water is 6~10 times of drug weight, decocts 1~3 hour.
6. the preparation method of the medicine for the treatment of breast carcinoma according to claim 3, it is characterized in that: the step 4 of the preparation method of medicine B), the dosage form of medicine B is tablet, granule or capsule.
CN201210497488.4A 2012-11-29 2012-11-29 Medicine for treating breast cancer and preparation method of medicine Expired - Fee Related CN102940765B (en)

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