CN102935167B - 一种治疗腹型癫痫综合征的中药 - Google Patents
一种治疗腹型癫痫综合征的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗腹型癫痫综合征的中药，由以下重量配比的药材制备而成：苦荞头12份、吴茱萸14份、地龙10份、穿心莲8份、重楼6份、苦荞头12份、九龙藤13份、三颗针13份、天青地白8份、牛膝12份、鸡血藤12份。临床实验证明，本发明能够安全有效治疗腹型癫痫综合征。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗腹型癫痫综合征的中药。
背景技术
腹型癫痫综合征（Abdominal Apoplexy Syndrome）是指以发作性腹痛为特点的一种癫痫。本病多见于儿童，成人则较罕见。男女发病率无明显差异。表现为突然发作性腹痛，部位多在脐周围及上腹部，疼痛多较剧烈，如绞痛或刀割样，持续时间几分钟，也可持续几小时以上。病因尚未明了。可能因头部外伤、结节性硬化、肿瘤及注射白喉抗毒素后引起神经血管性水肿等原因所致。
对于腹型癫痫综合征目前尚缺少公认安全有效的治疗药物。
本发明中药所涉及药材的研究现状如下：
鸡血藤【来源】豆科植物密花豆 Spatholobus suberectus Dunn 的干燥藤茎。【功能主治】性甘，温。归肝、肾经。功能主治:补血，活血，通络。用于月经不调，血虚萎黄，麻木瘫痪，风湿痹痛。
牛膝【来源】苋科植物牛膝 Achyranthes bidentata Bl. 的干燥根。牛膝根拣去杂质，洗净，润软，去芦，切段，晒干。酒牛膝：取牛膝段，用黄酒喷淋拌匀，闷润后，置锅内炒至微干，取出放凉即得。【功能主治】补肝肾；强筋骨；活血通经；引火（血）下行；利尿通淋。
天青地白【来源】于菊科植物日本鼠曲草全草。甘，凉。【功能主治】解表，清热，明目，利尿的功效。治疗感冒，咳嗽，头痛，喉痛，目赤翳鄣，小便热闭，淋浊，白带，痈肿，疔疮。
三颗针【来源】于小檗科植物刺黑珠、毛叶小檗、黑石珠等的根皮或茎皮。性寒，微苦。【功能主治】清热，利湿，散瘀的功效。治疗赤痢，黄疸，咽痛，目赤，跌打损伤。
九龙藤【来源】于豆科植物龙须藤的茎。苦辛，平，无毒。【功能主治】祛风、去瘀、止痛的作用。治疗风湿骨痛、跌打损伤。
苦荞头【来源】又称荞叶七苦荞麦、万年荞、野南荞、，一年生草本。为蓼科植物苦荞麦的根及根茎。【功能主治】治胃痛，消化不良，痢疾，劳伤，腰腿痛。
重楼【来源】：为百合科植物云南重楼Paris yunnanensis Franch. 的根茎。别名滇重楼、草河车、独脚莲。【功能主治】性微寒，味苦；有小毒。清热解毒，消肿止痛，凉肝定惊。作于疔肿痈肿、咽喉肿痛、毒蛇咬伤、跌扑伤痛、惊风抽搐。
穿心莲【来源】爵床科植物穿心莲（圆锥须药草）Andrographis paniculata （Burm. f.）Nees 的干燥地上部分。秋初茎叶茂盛时采割，晒干。 【功能主治】清热解毒，凉血，消肿，燥湿。主治：感冒发热，咽喉肿痛，口舌生疮，顿咳劳嗽，泄泻痢疾，热淋涩痛，痈肿疮疡，毒蛇咬伤。
地龙【来源】环节动物门钜蚓科动物参环毛蚓【功能主治】性寒，味咸。清热定惊，通络、平喘，利尿；用于高热神昏惊痫抽搐，关节麻痹，肢体麻木，半身不遂，肺热喘咳，尿少水肿，高血压症。
吴茱萸【来源】为芸香科植物吴茱萸Evodia rutaecarpa 的近成熟果实。【功能主治】其性热味苦寒，有散热止痛、降逆止呕之功，用于治疗肝胃虚寒、阴浊上逆所致的头痛或胃脘疼痛等症。
苦荞头【来源】又称荞叶七苦荞麦、万年荞、野南荞、，一年生草本。为蓼科植物苦荞麦的根及根茎。【功能主治】治胃痛，消化不良，痢疾，劳伤，腰腿痛。
发明内容
本发明旨在提供一种治疗腹型癫痫综合征的中药，通过选择合适的药材及其配比，达到安全有效治愈腹型癫痫综合征的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗腹型癫痫综合征的中药，其特征在于，由以下重量配比的药材制备而成：苦荞头12份、吴茱萸14份、地龙10份、穿心莲8份、重楼6份、苦荞头12份、九龙藤13份、三颗针13份、天青地白8份、牛膝12份、鸡血藤12份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年6月-2011年9月间共收集80例腹型癫痫综合征的门诊患者，随机分为：治疗组50例，空白组30例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗组口服本发明按照具体实施例1制得的胶囊，早晚各一次。疗程30天。
2.2空白组口服安慰剂胶囊，早晚各一次。疗程30天。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，病情得到控制，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) |
| 治疗组 | 50 | 10（20%） | 34（68%) | 6（12%) | 88% |
| 空白组 | 30 | 0 | 5（16.7%） | 25（83.3%） | 16.7% |
可见，本发明制得的药物能够安全有效治腹型癫痫综合征。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：苦荞头12克、吴茱萸14克、地龙10克、穿心莲8克、重楼6克、苦荞头12克、九龙藤13克、三颗针13克、天青地白8克、牛膝12克、鸡血藤12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗腹型癫痫综合征。口服，每日分早晚两次服用。
具体实施例2
称取：玄苦荞头12克、吴茱萸14克、地龙10克、穿心莲8克、重楼6克、苦荞头12克、九龙藤13克、三颗针13克、天青地白8克、牛膝12克、鸡血藤12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗腹型癫痫综合征。口服，每日分早晚两次服用。
具体实施例3
称取：苦荞头12克、吴茱萸14克、地龙10克、穿心莲8克、重楼6克、苦荞头12克、九龙藤13克、三颗针13克、天青地白8克、牛膝12克、鸡血藤12克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗腹型癫痫综合征。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗腹型癫痫综合征的中药，其特征在于，由以下重量配比的药材制备而成：苦荞头12份、吴茱萸14份、地龙10份、穿心莲8份、重楼6份、九龙藤13份、三颗针13份、天青地白8份、牛膝12份、鸡血藤12份；所述中药的制备方法为：称取上述重量配比的药材，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
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