CN102935082A - Drug for external use for preventing and treating scabies - Google Patents
Drug for external use for preventing and treating scabies Download PDFInfo
- Publication number
- CN102935082A CN102935082A CN2012104649820A CN201210464982A CN102935082A CN 102935082 A CN102935082 A CN 102935082A CN 2012104649820 A CN2012104649820 A CN 2012104649820A CN 201210464982 A CN201210464982 A CN 201210464982A CN 102935082 A CN102935082 A CN 102935082A
- Authority
- CN
- China
- Prior art keywords
- sheep
- preventing
- treating
- grams
- topical agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to a drug for external use for preventing and treating scabies, and mainly solves the problems that organic phosphorus medicines for preventing and treating scabies are high in toxicity, short in persistence and poor in therapy efficacy and pyrethroid medicines are high in expenses and easy to generate resistance in the prior art. The drug for external use is characterized by comprising, by weight, 30-45% of phoxim, 10-15% of fenvalerate, 5% of XN-100, 8-10% of 0301C, and the balance being dimethylbenzene. The drug for external use for preventing and treating scabies is low-cost, good in safety, good in therapy efficacy, long in persistence and not easy to generate resistance.
Description
Technical field
The present invention relates to a kind of medicament of preventing and treating sheep-scab, particularly a kind of topical agent of preventing and treating sheep-scab.
Background technology
Scabies is the main dermatosis of sheep, and the sheep mange tinea claims again the sheep acaricide, is a kind of parasitic disease that is caused by acaricide and itch mite.Primary disease is with direct or indirect contact transmission, and ill sheep itches, scytitis, loses hair or feathers and become thin as feature take play, can infect in a short time whole flock of sheep, endangers very serious.For the control of sheep mange tinea, take aggregate measures more.Dipping is to carry out dipping behind the requisite important process, particularly fine-wool sheep cropping in the sheep feeding and management, is the key measures of eliminating vermin and prevention mange and scab.General annual each dipping in spring and autumn once.The most frequently used medicine of sheep dipping is organic phosphates.But because in recent years, after the Ministry of Agriculture hereinafter completely forbids and sells at home and use γ-HCH, high malicious organophosphor medicine, existing medicine or because killing demodicid mite power is low, the lasting period is short, develop immunity to drugs easily that it is not good to cause clinical effectiveness, or because causing that very easily sheep only poisons, price is high; Adopt chrysanthemum esters medicine expense high, easily produce resistance, use and limited to.
Summary of the invention
The invention reside in overcome that exist in the background technology existing prevents and treats that the sheep mange tinea adopts the organic phosphates medicine or toxicity is large, poor stability or the lasting period is short, unsatisfactory curative effect and adopt chrysanthemum esters medicine expense high, easily produce the problem of resistance, and provide a kind of topical agent of preventing and treating sheep-scab, this topical agent cost is lower, safety is good, curative effect is good, long, the difficult resistance that produces of lasting period.
The present invention solves its problem and can reach by following technical solution: a kind of topical agent of preventing and treating sheep-scab, the component of this topical agent and the weight percentage of each component are: phoxim 30-45, fenvalerate 10-15, XN-100 are 5,0301C is 8-10, and surplus is dimethylbenzene.
The component of this topical agent and the weight percentage of each component are: phoxim 45, fenvalerate 15, XN-100 are 5,0301C is 10, and dimethylbenzene is 25.
Described phoxim: fenvalerate is 3:1.
The topical agent of this control sheep-scab is used for preventing and treating the sheep mange tinea.
This medicament dipping active drug concentration exists
200ppm-400ppmEmbrocating active drug concentration is
500-800ppm
The topical agent of control sheep-scab of the present invention can be embrocated again in dipping.General dipping once gets final product.Toxicity test shows, this medicine is good to domestic animal low toxicity, safety.
Embrocate treatment and suffer from sheep 1500 examples, cure rate 100%; Medicine bathing method for sheep more than 20,000 is (787 of trouble sheep) cure rate 100% only, and is respond well.
Acting as of this each composition of medicament: phoxim also has stomach poison function take action of contace poison as main to the evil demodicid mite, and the outdoor utility longevity of residure is short; It is strong that fenvalerate kills demodicid mite power, renders a service highly and certain, kills in addition the effect of demodicid mite ovum, and the longevity of residure is long, but easily produces resistance; Two medicines share can increase acaricidal activity, also can reduce simultaneously harmful demodicid mite resistance, when phoxim: when fenvalerate is 3:1, reach best composite effect; XN-100 has makes that medicinal liquid is moistening on fur, the function of spread, adhesion, medicinal liquid is fully contacted with evil demodicid mite and demodicid mite ovum and increases drug effect, prolongs the lasting period, also can reduce the dose loss; 0301C is the Compositional type emulsifying agent, has an emulsifiability good, the advantage of emulsion-stabilizing; To be solvent all have good dissolution to phoxim and fenvalerate and other composition to dimethylbenzene.
Said preparation is by stability test, distributed test, the test of pesticide effectiveness, toxicity test.Preserve under the room temperature and stablize, the medicine resolution ratio is low; Distributed test disperses Quick uniform in the media such as well water, river; Exsomatizing, demodicid mite test miticidal effect is remarkable extremely.The Clinical Treatment Test demonstration, said preparation is high to the sheep-scab curative effect, the lasting period is long; In the time of control sheep acaricide external other parasite of sheep such as Ticks, louse, mosquito, fly also there is fine repelling and killing efficacy.This medicine can be embrocated again in dipping.General dipping once gets final product.Toxicity test shows, this medicine is good to domestic animal low toxicity, safety.This reagent cost is lower, and is efficient, long-acting, resistance is low, safety, and price is suitable.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment:
Embodiment 1
Phoxim 45 restrains, fenvalerate 15 restrains,
XN-100Be that 5 grams, 0301C are 10 grams, dimethylbenzene is 25 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Embodiment 2
Phoxim 42 grams, fenvalerate 14 grams, XN-100 are that 5 grams, 0301C are 10 grams, dimethylbenzene 29 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Embodiment 3
Phoxim 39 grams, fenvalerate 13 grams, XN-100 are that 5 grams, 0301C are 9 grams, solvent naphtha 34 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Embodiment 4
Phoxim 36 grams, fenvalerate 12 grams, XN-100 are that 5 grams, 0301C are 9 grams, solvent naphtha 38 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Embodiment 5
Phoxim 33 grams, fenvalerate 11 grams, XN-100 are that 5 grams, 0301C are 8 grams, dimethylbenzene 43 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Embodiment 6
Phoxim 30 grams, fenvalerate 10 grams, XN-100 are that 5 grams, 0301C are 8 grams, dimethylbenzene 47 grams; Be mixed and made into emulsifiable concentrate for subsequent use.
Above-described embodiment institute medication composition is all commercially available, and the manufacturer of XN-100 is Changxing, Qingdao chemical industry company limited; The manufacturer of 0301C is silver field, Henan Fine Chemical Co., Ltd.
When this medicament was used for preventing and treating the sheep mange tinea, dipping active drug concentration was at 200ppm-400ppm, and replenishing dipping active drug concentration is 500ppm; Embrocating active drug concentration is 500-800ppm.
The medicament of Application Example 1 preparation, be made into 200ppm-400ppm concentration, 20,000 sheep have been carried out dipping, wherein, 8000 of the end of spring and the beginning of summer medicine bathing method for sheep (suffering from 787 of sheep), 3 days trouble sheep gargalesthesias disappear after the dipping, appetite increases, new fine hair appears in the affected part after 7 days, grows the 1-1.6cm virgin wool after one month, and all tracing study only had no the morbidity sheep in 3 months.1.2 ten thousand of medicine bathing method for sheep (without suffering from sheep) at the beginning of autumn late summer, all tracing study had no the scabies generation in 8 months.The medicament of Application Example 1 preparation, be made into 500-800ppm concentration, 1500 sick sheep are carried out affected part embrocate treatment, embrocate together with skin on every side and hair in the affected part when embrocating, drip as degree to soak, the lighter can embrocate once, and severe one can be embrocated 2-3 time, embrocated the interval one day, cure rate is 100% at every turn.
Claims (5)
1. topical agent of preventing and treating sheep-scab, it is characterized in that: the component of this topical agent and the weight percentage of each component are: phoxim 30-45, fenvalerate 10-15, XN-100 are 5,0301C is 8-10, and surplus is dimethylbenzene.
2. a kind of topical agent of preventing and treating sheep-scab according to claim 1, it is characterized in that: the component of this topical agent and the weight percentage of each component are: phoxim 45, fenvalerate 15, XN-100 are 5,0301C is 10, and dimethylbenzene is 25.
3. a kind of topical agent of preventing and treating sheep-scab according to claim 1, it is characterized in that: described phoxim: fenvalerate is 3:1.
4. claim 1 or the 2 described a kind of application of topical agent in preventing and treating the sheep mange tinea that prevent and treat sheep-scab.
5. a kind of application of topical agent in preventing and treating the sheep mange tinea that prevents and treats sheep-scab according to claim 4, it is characterized in that: this medicament dipping active drug concentration is at 200ppm-400ppm; Embrocating active drug concentration is 500-800ppm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210464982.0A CN102935082B (en) | 2012-11-19 | 2012-11-19 | Drug for external use for preventing and treating scabies |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210464982.0A CN102935082B (en) | 2012-11-19 | 2012-11-19 | Drug for external use for preventing and treating scabies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102935082A true CN102935082A (en) | 2013-02-20 |
| CN102935082B CN102935082B (en) | 2015-06-17 |
Family
ID=47694029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210464982.0A Expired - Fee Related CN102935082B (en) | 2012-11-19 | 2012-11-19 | Drug for external use for preventing and treating scabies |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102935082B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362287A (en) * | 2015-12-17 | 2016-03-02 | 山东省农业科学院畜牧兽医研究所 | Disinfecting shower cream for pigs |
| CN106070301A (en) * | 2016-06-01 | 2016-11-09 | 武汉中博绿亚生物科技有限公司 | A kind of for compound recipe spray treating dog-tick insect infection and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171885A (en) * | 1996-07-26 | 1998-02-04 | 安徽省岳西县有机化工厂 | Compound emulsion |
-
2012
- 2012-11-19 CN CN201210464982.0A patent/CN102935082B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1171885A (en) * | 1996-07-26 | 1998-02-04 | 安徽省岳西县有机化工厂 | Compound emulsion |
Non-Patent Citations (3)
| Title |
|---|
| 梁庭敏 等: "山羊群发疫病的防治对策", 《当代畜牧》, no. 3, 31 December 2006 (2006-12-31), pages 16 - 17 * |
| 穆永才 等: "羊疥癣病的药物防治", 《黑龙江畜牧科技》, 31 December 1997 (1997-12-31), pages 13 - 14 * |
| 闫金华: "用辛硫磷药浴防治羊疥癣病效果好", 《农村养殖技术》, no. 17, 31 December 2006 (2006-12-31), pages 26 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105362287A (en) * | 2015-12-17 | 2016-03-02 | 山东省农业科学院畜牧兽医研究所 | Disinfecting shower cream for pigs |
| CN105362287B (en) * | 2015-12-17 | 2017-12-29 | 山东省农业科学院畜牧兽医研究所 | One boar sterilization bath oil |
| CN106070301A (en) * | 2016-06-01 | 2016-11-09 | 武汉中博绿亚生物科技有限公司 | A kind of for compound recipe spray treating dog-tick insect infection and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102935082B (en) | 2015-06-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101940227A (en) | Cool and refreshing insect-repelling air-purification disinfectant and preparation method thereof | |
| CN102935082B (en) | Drug for external use for preventing and treating scabies | |
| CN104542690B (en) | A kind of gamma cyhalothrin breast granule, its preparation method and application thereof | |
| CN102823584B (en) | Plant-source hot fogging concentrate for preventing and controlling whitefly insects and preparation method thereof | |
| CN102805082B (en) | A kind of agricultural chemicals synergist | |
| CN105410013A (en) | Insecticide-pesticide mixture preparation | |
| CN1951484A (en) | Oil for treating wounds | |
| CN108124862A (en) | A kind of builder and its application method for killing snout moth's larva medicament | |
| CN104396957A (en) | Microemulsion for controlling tea-tree tea geometrid | |
| CN101732288B (en) | Emulsifying agent for treating rabbit sarcoptidosis and killing mites in rabbit hutch | |
| CN104488956A (en) | Pharmaceutical composition for preventing and treating radopholus similis | |
| CN103975937A (en) | Synergistic mite killing composition containing bifenazate and flufenoxuron | |
| CN102365961B (en) | Insecticidal composition | |
| CN113498783A (en) | Mite-killing missible oil and preparation method and application thereof | |
| CN103039456B (en) | Synergistic insecticidal composition containing tolfenpxrad and S-fenvalerate and application thereof | |
| CN106109588A (en) | A kind of spray treating tinea pedis and preparation method thereof | |
| CN100588320C (en) | Acetamiprid and pirimicarb pesticidal composition for controlling erisosma lanigerum hausmann and aphis citricola | |
| Amfim et al. | Epidemiological and therapeutics approachs in cats pyrethroids poisoning | |
| CN107751240A (en) | A kind of composition pesticide of containing chlopyrifos | |
| CN100433980C (en) | Cyhalothrin-pleocidin water emulsion and preparation method thereof | |
| CN105557760A (en) | Synergistic insecticidal composition containing propargite and tetranactin, and application thereof | |
| Elibol et al. | Case Report Do Inhaled Pesticides Cause Dystonic Reactions? Case Report from a Paediatric Emergency Room | |
| Taylor | Why are cats still dying from permethrin toxicity | |
| CN103039502A (en) | Pesticide composition of phoxim and hexaflumuron | |
| CN103749524A (en) | Pesticide |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20170605 Address after: 161000 Qigihar City, Heilongjiang province Jianhua district west two Street No. 112 provincial Veterinary Institute Co-patentee after: Qingdao Huifeng Animal Health-Care Products Co., Ltd. Patentee after: Mu Yongcai Address before: 161000 Qigihar City, Heilongjiang province Jianhua district west two Street No. 112 provincial Veterinary Institute Patentee before: Mu Yongcai |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150617 Termination date: 20181119 |