CN102933599A - 包含额外的二硫键的人胰岛素 - Google Patents
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- CN102933599A CN102933599A CN2011800295163A CN201180029516A CN102933599A CN 102933599 A CN102933599 A CN 102933599A CN 2011800295163 A CN2011800295163 A CN 2011800295163A CN 201180029516 A CN201180029516 A CN 201180029516A CN 102933599 A CN102933599 A CN 102933599A
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- insulin
- human insulin
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- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10167036.2 | 2010-06-23 | ||
| EP10167036 | 2010-06-23 | ||
| US35912710P | 2010-06-28 | 2010-06-28 | |
| US61/359,127 | 2010-06-28 | ||
| PCT/EP2011/060295 WO2011161083A1 (en) | 2010-06-23 | 2011-06-21 | Human insulin containing additional disulfide bonds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102933599A true CN102933599A (zh) | 2013-02-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800295163A Pending CN102933599A (zh) | 2010-06-23 | 2011-06-21 | 包含额外的二硫键的人胰岛素 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8883722B2 (enExample) |
| EP (1) | EP2585483A1 (enExample) |
| JP (1) | JP6013330B2 (enExample) |
| CN (1) | CN102933599A (enExample) |
| WO (1) | WO2011161083A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103533952A (zh) * | 2011-03-15 | 2014-01-22 | 诺沃—诺迪斯克有限公司 | 包含半胱氨酸置换的人胰岛素类似物和衍生物 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104693302A (zh) | 2010-06-23 | 2015-06-10 | 诺沃—诺迪斯克有限公司 | 包含额外的二硫键的胰岛素衍生物 |
| JP2015502971A (ja) * | 2011-12-21 | 2015-01-29 | ノヴォ ノルディスク アー／エス | Ｎ末端修飾インスリン誘導体 |
| GB2555639B (en) | 2016-11-07 | 2022-02-09 | Rheon Labs Ltd | Activity monitoring |
| CN111781288B (zh) * | 2020-07-23 | 2023-10-31 | 中国计量科学研究院 | 确定多肽二硫键位置的方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009087081A2 (de) * | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | Neue insulinderivate mit extrem verzögertem zeit-/wirkungsprofil |
| CN101541830A (zh) * | 2006-09-22 | 2009-09-23 | 诺沃-诺迪斯克有限公司 | 蛋白酶抗性的胰岛素类似物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE50892B1 (en) | 1980-02-11 | 1986-08-06 | Novo Industri As | Process for preparing insulin esters |
| DK58285D0 (da) | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| DK105489D0 (da) | 1989-03-03 | 1989-03-03 | Novo Nordisk As | Polypeptid |
| DK155690D0 (da) * | 1990-06-28 | 1990-06-28 | Novo Nordisk As | Nye peptider |
| ZA954983B (en) | 1994-06-17 | 1996-02-14 | Novo Nordisk As | N-terminally extended proteins expressed in yeast |
| RU2283846C2 (ru) | 1999-12-29 | 2006-09-20 | Ново Нордиск А/С | Предшественник инсулина, способ его получения и применение |
| AU2003903124A0 (en) * | 2003-06-20 | 2003-07-10 | Mark Del Borgo | Analogues of heteromeric proteins |
| JP4463814B2 (ja) | 2003-08-05 | 2010-05-19 | ノボ ノルディスク アクティーゼルスカブ | 新規のインスリン誘導体 |
| WO2007135117A2 (en) * | 2006-05-24 | 2007-11-29 | Novo Nordisk A/S | Soluble, stable insulin-containing formulations |
| ES2618073T3 (es) * | 2008-03-14 | 2017-06-20 | Novo Nordisk A/S | Análogos de insulina estabilizados frente a proteasas |
| EP2376531A1 (en) | 2008-12-09 | 2011-10-19 | Novo Nordisk A/S | Novel insulin analogues |
| US20120184488A1 (en) | 2009-09-01 | 2012-07-19 | Case Western Reserve University | Insulin analogues of enhanced receptor-binding specificity |
-
2011
- 2011-06-21 WO PCT/EP2011/060295 patent/WO2011161083A1/en not_active Ceased
- 2011-06-21 EP EP11726432.5A patent/EP2585483A1/en not_active Withdrawn
- 2011-06-21 JP JP2013515850A patent/JP6013330B2/ja not_active Expired - Fee Related
- 2011-06-21 US US13/805,494 patent/US8883722B2/en not_active Expired - Fee Related
- 2011-06-21 CN CN2011800295163A patent/CN102933599A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101541830A (zh) * | 2006-09-22 | 2009-09-23 | 诺沃-诺迪斯克有限公司 | 蛋白酶抗性的胰岛素类似物 |
| WO2009087081A2 (de) * | 2008-01-09 | 2009-07-16 | Sanofi-Aventis Deutschland Gmbh | Neue insulinderivate mit extrem verzögertem zeit-/wirkungsprofil |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103533952A (zh) * | 2011-03-15 | 2014-01-22 | 诺沃—诺迪斯克有限公司 | 包含半胱氨酸置换的人胰岛素类似物和衍生物 |
| US9187547B2 (en) | 2011-03-15 | 2015-11-17 | Novo Nordisk A/S | Human insulin analogues and derivatives comprising cysteine substitutions |
Also Published As
| Publication number | Publication date |
|---|---|
| US20130178414A1 (en) | 2013-07-11 |
| JP2013532970A (ja) | 2013-08-22 |
| US8883722B2 (en) | 2014-11-11 |
| JP6013330B2 (ja) | 2016-10-25 |
| EP2585483A1 (en) | 2013-05-01 |
| WO2011161083A1 (en) | 2011-12-29 |
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Application publication date: 20130213 |