CN102920890B - Traditional Chinese medicinal composition for treating fever diseases of poultries - Google Patents

Abstract

The invention belongs to the field of traditional Chinese veterinary medicinal preparations, and relates to a traditional Chinese medicinal composition for treating fever diseases of poultries. The traditional Chinese medicinal composition is prepared from Radix Astragali, Radix Codonopsis, honeysuckle flower, Weeping Forsythia, isatis root, Natural Indigo, Venenum Bufonis, Rhizoma Paridis, Panax Notoginseng, Incised Notopterygium, prepared Radix aconiti lateralis preparata, Rheum officinale, borneol, gypsum rubrum and artificial Calculus Bovis. The traditional Chinese medicinal composition has the efficacies of heat clearing, detoxifying, pain easing, lung diffusing, exterior syndrome relieving, spleen invigorating, qi reinforcing, and body immunity adjusting. Multi-time laboratorial and clinic practice examination results show that the traditional Chinese medicinal composition has the characteristics of reasonable formula, simple process, stable quality, low cost, small toxic side effects and the like, has a good effect on the control of the fever diseases of the poultries, and has a great market potential.

Description

A kind of Chinese medicine composition for the treatment of poultry temperature febrile illness

Technical field

The invention belongs to herbal medicine formulation art, relate to a kind of Chinese medicine composition for the treatment of poultry temperature febrile illness.

Background technology

Temperature febrile illness comprises the febrile diseases such as poultry newcastle, influenza, very harmful to poultry husbandry.Primary disease is not subject to seasonal effect, and the chicken at various ages all can infection morbidity, propagates soon, and the resistance of M & M and chicken is relevant with viral virulence.Fervescence, spirit is tired, does not eat, slow-witted vertical.Disorderly, head, wing and tail are sagging, close one's eyes as lethargy shape for feather pine, hat and wattle are red or mulberry, diarrhoea, feces yellow green or yellow-white, sialorrhea, constantly shake the head and swallow, dyspnea, and send the sound of " chuckleing ", in crop, be full of liquid contents, while holding, there is the smelly liquid of a large amount of acid to flow out in mouth, death in 2～4 days.Chronic type: send various nervous symptoms, head is to layback or amesiality, and lower limb is benumbed, and wing is sagging, and movement disorder is paralysed and death.The not dead nervous symptoms of also having left over, long-term band poison.Bird flu is that the one of the poultry that caused by A type influenza virus and wild fowl is from respiratory system to various diseases syndromes such as serious whole body septicemia.Be worldwide popular, China also has primary disease to occur in recent years, and is on the rise, and has caused huge economic loss to aviculture.A type influenza virus can infect multiple poultry and wild fowl, popularity because of strain and animal species different, the susceptible of turkey in poultry.Primary disease can be propagated through number of ways, as digestive tract, respiratory tract, damaged skin mucosa etc.General sickness rate is high, and mortality rate is low, but when highly pathogenicity virus strain infection, sickness rate, mortality rate all can reach 100%.The depressed sick Caput Gallus domesticus of general common spirit portion, eyelid swelling conjunctival congestion, hemorrhage around, and flow out the swelling of viscosity nasal mucus hat whisker, cyanosis hemorrhage, downright bad sick chicken dysentery when serious, arrange the sick drumsticks of green feces portion dermathemia, hemorrhage

In current existing technology, the modern veterinary treatment multiplex antiviral Western medicine of this class disease or genetic engineering interferon coordinate the methods such as ntipyretic analgesic medicine, as: ribavirin, amantadine, moroxydine etc., its shortcoming is to cure the symptoms, not the disease, the course for the treatment of is long, weak curative effect, some medicine toxic side effect, the said medicine Ministry of Agriculture has been defined as forbidden drugs.The methods such as the multiplex heat-clearing and toxic substances removing of this class of Chinese veterinarian's veterinary treatment disease, blood circulation promoting and blood stasis dispelling, its shortcoming be dosage large, take effect slow, cure rate is low, use is inconvenient.

Summary of the invention

The object of this invention is to provide that a kind of technique is simple, the Chinese medicine composition of steady quality, treatment poultry temperature febrile illness with low cost, evident in efficacy.

For realizing object of the present invention, existing according to following technical scheme, this injection is to be made up of the raw material of following weight portion proportioning:

Radix Astragali 3-8 part, Radix Codonopsis 6-10 part, Flos Lonicerae 6-10 part, Fructus Forsythiae 6-10 part, Radix Isatidis 6-10 part, Indigo Naturalis 6-10 part, Venenum Bufonis 0,5-2 part, Rhizoma Paridis 8-12 part, Radix Notoginseng 6-10 part, Rhizoma Et Radix Notopterygii 6-10 part, Radix Aconiti Lateralis Preparata 3-8 part, Radix Et Rhizoma Rhei 5-10 part, Borneolum Syntheticum 3-8 part, Mirabilitum crystallina 3-8 part, artificial Calculus Bovis 1-4 part.

The weight proportion of the best each raw material of formula of the present invention is:

5 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 8 parts of Flos Loniceraes, 8 parts of Fructus Forsythiaes, 8 parts of Radix Isatidis, 8 parts of Indigo Naturaliss, 1 part of Venenum Bufonis, 10 parts of Rhizoma Paridis, 8 parts of Radix Notoginseng, 8 parts of Rhizoma Et Radix Notopterygiis, 5 parts of Radix Aconiti Lateralis Preparata, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Borneolum Syntheticums, 6 parts of Mirabilitum crystallinas, 3 parts of artificial Calculus Boviss.

Side separates:

The Radix Astragali: have effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst.

Radix Codonopsis: there is invigorating the spleen and replenishing QI, effect of spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc.

Flos Lonicerae: cold in nature, there is the effect of heat-clearing and toxic substances removing, dispelling wind and heat pathogens.Flos Lonicerae has heat-clearing and toxic substances removing, dredges the effect of throat, the relieving restlessness of relieving summer heat.Can treat the diseases such as febrile disease due to summer-heat pathogen, dysentery, influenza, furuncle toxic swelling, acute and chronic tonsillitis, periodontitis.

Fructus Forsythiae: cure mainly calentura from the beginning of, anemopyretic cold, heating, vexed, laryngopharynx swelling and pain, acute nephritis etc.

Radix Isatidis: heat clearing away, removing toxic substances, removing heat from blood, sore-throat relieving.Modern pharmacological research has resisting pathogenic microbes effect Isatis indigotica Fort. root various bacteria is had to inhibitory action. and infusion has inhibitory action in various degree to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, Salmonella paratyphi, dysentery (will he, Fu Shi) bacillus, bacillus enteritidis etc.

Indigo Naturalis: heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, purging liver-fire, arresting convulsion.For maculae caused by violent heat pathogen, heat in blood is told nosebleed, chest pain hemoptysis, aphtha, mumps, sore throat.

Venenum Bufonis: modern pharmacological research has fungistatic effect obviously, rapidly, insensitive or antibiotic has been produced to the suppurative illness of drug resistance to some antibiotic, this product also has inhibition.

Rhizoma Paridis: for popular rib adenitis, tonsillitis, swelling throat educate, otitis media, epidemic encephalitis type B, cruchet's disease etc.

Radix Notoginseng: dissipating blood stasis hemostasis, subduing swelling and relieving pain.For various inside and outside hemorrhage, spitting of blood, spits blood, and epistaxis, has blood in stool, metrorrhagia, breast ventral spine pain, tumbling and swelling.

Rhizoma Et Radix Notopterygii: loose exterior cold; Wind-damp dispelling; Profit joint; Pain relieving.For cold, the diseases such as fever with chills.

Radix Aconiti Lateralis Preparata: all there is antiinflammatory, analgesia and local anesthetic action.Can strengthen myocardial contraction, accelerate heart rate, increase cardiac output, increase myocardial oxygen consumption.

Radix Et Rhizoma Rhei: attack stagnant; Clearing away damp-heat; Pathogenic fire purging; Removing heat from blood; Blood stasis dispelling; Removing toxic substances.

Borneolum Syntheticum: control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.

Mirabilitum crystallina: clearing away heat-fire, sharp key, detumescence.

Artificial Calculus Bovis: there is clearing away heart-fire detoxification, the eliminating phlegm of having one's ideas straightened out, the function of dispelling wind and relieving convulsion.Be usually used in treating calentura coma, middle wind-phlegm fan, faints from fear and twitches, laryngopharynx swelling and pain, mouthful raw skin ulcer, the diseases such as carbuncle furuncle.

The preparation method of Chinese medicine composition of the present invention is:

1), take medical material by prescription proportioning for subsequent use;

2), the Radix Astragali, Radix Codonopsis, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Paridis, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei, Borneolum Syntheticum, Mirabilitum crystallina 12 taste medical materials were pulverized respectively to 120 mesh sieves, then add Indigo Naturalis, artificial Calculus Bovis's mix homogeneously to make mixed powder A, for subsequent use;

3), Venenum Bufonis is boiled to 8-10 minute with 50 times of decoctings, cool, make Venenum Bufonis liquid B, for subsequent use;

4), mixed powder A is poured in the container of Venenum Bufonis liquid B and stirs, after oven drying at low temperature, pulverized 100 mesh sieves, subpackage,, to obtain final product by every bag heavy 100 grams.

The present invention has heat-clearing and toxic substances removing, analgesia, diffusing lung, relieving exterior syndrome, spleen invigorating QI invigorating, regulates effect of body immunity.Show through many experiments chamber and clinical practice assay, the features such as this medicine composition is reasonable, technique simple, steady quality, with low cost, toxic and side effects is little, are that the control of poultry febrile disease is had to good effect, have huge market potential.

Using method of the present invention is: 0.2 gram of the each medication of per kilogram of body weight poultry, chickling is cut down according to the circumstance, once a day.Boiling water adds the even spice of appropriate ordinary water after washing open, allow chicken group eat up for 2-3 hour.Be used in conjunction 2-3 days, can fully recover.

Compared with Chinese medicine, large general every of Chinese medicine consumption becomes chicken to need 2 grams of left and right, and this product only needs 0.5 gram.Chinese medicine is longer the course for the treatment of, is generally 4-5 days, this product 2-3 days.

The specific embodiment:

Take raw material in following ratio: 5 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 8 parts of Flos Loniceraes, 8 parts of Fructus Forsythiaes, 8 parts of Radix Isatidis, 8 parts of Indigo Naturaliss, 1 part of Venenum Bufonis, 10 parts of Rhizoma Paridis, 8 parts of Radix Notoginseng, 8 parts of Rhizoma Et Radix Notopterygiis, 5 parts of Radix Aconiti Lateralis Preparata, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Borneolum Syntheticums, 6 parts of Mirabilitum crystallinas, 3 parts of artificial Calculus Boviss.

The preparation method of Chinese medicine composition of the present invention is:

1), take medical material by prescription proportioning for subsequent use;

2), the Radix Astragali, Radix Codonopsis, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Paridis, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei, Borneolum Syntheticum, Mirabilitum crystallina 12 taste medical materials were pulverized respectively to 120 mesh sieves, then add Indigo Naturalis, artificial Calculus Bovis's mix homogeneously to make mixed powder A, for subsequent use;

3), Venenum Bufonis is boiled to 8-10 minute with 50 times of decoctings, cool, make Venenum Bufonis liquid B, for subsequent use;

4), mixed powder A is poured in the container of Venenum Bufonis liquid B and stirs, after oven drying at low temperature, pulverized 100 mesh sieves, subpackage,, to obtain final product by every bag heavy 100 grams.

For showing the therapeutic effect of medicine of the present invention to warm febrile illness bag (poultry newcastle, influenza), the inventor has carried out the observation of clinical treatment to 3000 sick chickens.By taking medicine of the present invention, 0.2 gram of the each medication of per kilogram of body weight poultry, boiling water adds the even spice of appropriate ordinary water after washing open, allow chicken group eat up for 2-3 hour, continuous use 3 days.Result is cured 2800, and effectively effective percentage is 98.3% to 93%, 2950 of cure rate, continuous use 1---3 days, and major part can be fully recovered, and does not stay any sequela after controlling.Use medicine of the present invention to improve more than 2 times than general Chinese Herbs through test, cure rate is high, and instant effect is cost-saving.

Claims (3)

1. treat a Chinese medicine composition for poultry temperature febrile illness, it is characterized in that it is made up of the raw material of following weight portion proportioning:

Radix Astragali 3-8 part, Radix Codonopsis 6-10 part, Flos Lonicerae 6-10 part, Fructus Forsythiae 6-10 part, Radix Isatidis 6-10 part, Indigo Naturalis 6-10 part, Venenum Bufonis 0,5-2 part, Rhizoma Paridis 8-12 part, Radix Notoginseng 6-10 part, Rhizoma Et Radix Notopterygii 6-10 part, Radix Aconiti Lateralis Preparata 3-8 part, Radix Et Rhizoma Rhei 5-10 part, Borneolum Syntheticum 3-8 part, Mirabilitum crystallina 3-8 part, artificial Calculus Bovis 1-4 part.

2. a kind of Chinese medicine composition for the treatment of poultry temperature febrile illness according to claim 1, is characterized in that the weight ratio of each raw material is: 5 parts of the Radixs Astragali, 8 parts of Radix Codonopsis, 8 parts of Flos Loniceraes, 8 parts of Fructus Forsythiaes, 8 parts of Radix Isatidis, 8 parts of Indigo Naturaliss, 1 part of Venenum Bufonis, 10 parts of Rhizoma Paridis, 8 parts of Radix Notoginseng, 8 parts of Rhizoma Et Radix Notopterygiis, 5 parts of Radix Aconiti Lateralis Preparata, 7 parts of Radix Et Rhizoma Rhei, 5 parts of Borneolum Syntheticums, 6 parts of Mirabilitum crystallinas, 3 parts of artificial Calculus Boviss.

3. the preparation method of a kind of Chinese medicine composition for the treatment of poultry temperature febrile illness according to claim 1 and 2, is characterized in that:

1), take medical material by prescription proportioning for subsequent use;

2), the Radix Astragali, Radix Codonopsis, Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Paridis, Radix Notoginseng, Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, Radix Et Rhizoma Rhei, Borneolum Syntheticum, Mirabilitum crystallina 12 taste medical materials were pulverized respectively to 120 mesh sieves, then add Indigo Naturalis, artificial Calculus Bovis's mix homogeneously to make mixed powder A, for subsequent use;

3), Venenum Bufonis is boiled to 8-10 minute with 50 times of decoctings, cool, make Venenum Bufonis liquid B, for subsequent use;

4), mixed powder A is poured in the container of Venenum Bufonis liquid B and stirs, after oven drying at low temperature, pulverized 100 mesh sieves, subpackage,, to obtain final product by every bag heavy 100 grams.