CN102911232B - 一种黄体酮的制备方法 - Google Patents
一种黄体酮的制备方法 Download PDFInfo
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- CN102911232B CN102911232B CN201210432390.0A CN201210432390A CN102911232B CN 102911232 B CN102911232 B CN 102911232B CN 201210432390 A CN201210432390 A CN 201210432390A CN 102911232 B CN102911232 B CN 102911232B
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CN102911232B true CN102911232B (zh) | 2015-03-11 |
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Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103450306B (zh) * | 2013-08-27 | 2016-01-27 | 西安高远生化有限责任公司 | 一种孕烯醇酮醋酸酯的合成方法 |
CN103776935B (zh) * | 2014-02-21 | 2017-02-01 | 陕西汉江药业集团股份有限公司 | 一种测定黄体酮生产母液中主要成分含量的方法 |
CN107417756A (zh) * | 2017-05-16 | 2017-12-01 | 浙江神洲药业有限公司 | 一种黄体酮晶型及其制备方法 |
CN107129516B (zh) * | 2017-06-16 | 2019-05-21 | 上海共拓医药化工有限公司 | 黄体酮的制备方法 |
CN112851736A (zh) * | 2021-03-08 | 2021-05-28 | 河北今水生物科技有限公司 | 一种黄体酮生产工艺 |
CN113999275A (zh) * | 2021-11-30 | 2022-02-01 | 陕西众和振华生物科技有限公司 | 一种黄体酮母液综合回收处理的碳中和工艺 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2601287A (en) * | 1949-08-18 | 1952-06-24 | Upjohn Co | Partial synthesis of progesterone |
GB679775A (en) * | 1949-08-18 | 1952-09-24 | Upjohn Co | Partial synthesis of progesterone |
US5164302A (en) * | 1987-02-06 | 1992-11-17 | Snow Brand Milk Products Company, Limited | Method for preparing 7β-hydroxy-4-pregnene-3,20-dione derivatives |
SE509004C2 (sv) * | 1996-02-16 | 1998-11-23 | Baeckvall Jan Erling | En metod för oxidation av 3 beta-hydroxisteroider i närvaro av ett katalytiskt system innehållande ett ruthenium (II)- komplex |
WO2010079594A1 (ja) * | 2009-01-07 | 2010-07-15 | 三菱化学株式会社 | ステロール側鎖切断酵素蛋白質およびその利用 |
CN102060901A (zh) * | 2011-01-14 | 2011-05-18 | 湖北芳通药业股份有限公司 | 由双烯醇酮醋酸酯合成黄体酮的工艺方法 |
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- 2012-11-02 CN CN201210432390.0A patent/CN102911232B/zh active Active
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2601287A (en) * | 1949-08-18 | 1952-06-24 | Upjohn Co | Partial synthesis of progesterone |
GB679775A (en) * | 1949-08-18 | 1952-09-24 | Upjohn Co | Partial synthesis of progesterone |
US5164302A (en) * | 1987-02-06 | 1992-11-17 | Snow Brand Milk Products Company, Limited | Method for preparing 7β-hydroxy-4-pregnene-3,20-dione derivatives |
SE509004C2 (sv) * | 1996-02-16 | 1998-11-23 | Baeckvall Jan Erling | En metod för oxidation av 3 beta-hydroxisteroider i närvaro av ett katalytiskt system innehållande ett ruthenium (II)- komplex |
WO2010079594A1 (ja) * | 2009-01-07 | 2010-07-15 | 三菱化学株式会社 | ステロール側鎖切断酵素蛋白質およびその利用 |
CN102060901A (zh) * | 2011-01-14 | 2011-05-18 | 湖北芳通药业股份有限公司 | 由双烯醇酮醋酸酯合成黄体酮的工艺方法 |
Non-Patent Citations (6)
Title |
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A Synthesis of Progesterone from Ergosterol;D.A.SHEPHERRD 等;《J. Am. Chem. Soc.》;19550305;第77卷(第5期);第1212-1215页 * |
Baeyer-Villiger oxidation of DHEA, pregnenolone, and androstenedione by Penicillium lilacinum AM111;Teresa Kolek 等;《Steroids》;20080805;第73卷(第14期);第1441-1445页 * |
Stereospecific Total Synthesis of Steroids via Isoxazole Annelation. dl-D-Homotestosterone and dl-Progesterone;Gilbert Stork 等;《J. Am. Chem. Soc.》;19671011;第89卷(第21期);第5464-5465页 * |
Sterols. CXII. Sapogenins. XLI. The Preparation of Trillin and its Conversion to Progesterone;RUSSELL E. MARKER等;《J. Am. Chem. Soc.》;19401231;第62卷(第9期);第3349-3350页,尤其是第3350页左栏倒数第8-9行 * |
Studies on Baeyer–Villiger oxidation of steroids: DHEA and pregnenolone d-lactonization pathways in Penicillium camemberti AM83;Teresa Kolek 等;《Steroids》;20090528;第74卷(第10-11期);第859-862页 * |
由孕甾-3S,5R,6R,16S,20S-五醇合成黄体酮;季菲 等;《化学学报》;20101130;第68卷(第22期);第2331-2337页 * |
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Application publication date: 20130206 Assignee: HUBEI DANJIANGKOU DANAO PHARMACEUTICAL CHEMICAL CO., LTD. Assignor: Wuhan Institute of Technology Contract record no.: 2015420000053 Denomination of invention: Progesterone preparation method Granted publication date: 20150311 License type: Exclusive License Record date: 20150417 |
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