CN102895418A - Traditional Chinese medical composition for treatment of sheep pox - Google Patents

Traditional Chinese medical composition for treatment of sheep pox Download PDF

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CN102895418A
CN102895418A CN2012104254328A CN201210425432A CN102895418A CN 102895418 A CN102895418 A CN 102895418A CN 2012104254328 A CN2012104254328 A CN 2012104254328A CN 201210425432 A CN201210425432 A CN 201210425432A CN 102895418 A CN102895418 A CN 102895418A
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parts
radix
sheep
treatment
sheep pox
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CN102895418B (en
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裴毅
王洪杰
刘志辉
苏永鹏
黄健
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TIANJIN JIHE TECHNOLOGY CO LTD
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Abstract

The invention provides a traditional Chinese medical composition for treatment of sheep pox. The traditional Chinese medical composition consists of the following components by weight: 1-120 parts of honeysuckle, 1-120 parts of wild chrysanthemum, 1-120 parts of dandelion, 1-120 parts of herba violae, 1-115 parts of radix scutellariae, 1-115 parts of radix isatidis, 1-110 parts of cimicifugae foetidae, 1-115 parts of lithospermum, 1-110 parts of semiaquilegia root and 1-110 parts of liquorice. According to a method of Chinese veterinary dialectical treatment, the honeysuckle, the wild chrysanthemum, the dandelion, the herba violae, the radix scutellariae, the radix isatidis, the cimicifugae foetidae, the lithospermum, the semiaquilegia root and the liquorice are used together, a contagious disease caused by a sheep pox virus, namely sheep pox, can be treated effectively, typical smallpox on the body skin and sometimes the mucosa can be alleviated effectively, and the high mortality caused by fever of ill sheep can be reduced significantly.

Description

A kind of Chinese medicine composition for the treatment of sheep pox
Technical field
The invention belongs to field of traditional Chinese veterinary, especially relate to a kind of Chinese medicine composition for the treatment of sheep pox.
Background technology
Sheep pox (sheep pox, SP) has another name called sheep pox (variola ovina), is a kind of contagious disease that sheep pox virus (sheep poxvirus, SPV) causes, is popular.Its feature is at whole skin, sometimes also typical varioliform exanthema occurs at mucosa, and sick sheep heating also has higher mortality rate.
Sheep pox all has popular in most of sheep manufacturing country.Algeria, Chad, Ethiopia, Kenya, Libya, Mali, Morocco, Nigeria, Senegal, the Sudan, Tunisia and the Egypt in Africa all once reported sheep pox and goatpox.The Afghanistan in Asia, India, Pakistan, Tu Er its, primary disease also occured in Iran, Iraq, Israel, Jordan, Kuwait, Lebanon, Nepal and Saudi Arabia.In addition, nineteen eighty-three Greece, Sweden and Italy primary disease also all occured.This sick mortality rate is very high, the morbidity fatality rate of lamb even up to 100%, and pregnant ewe is often miscarried, and most sheep are namely lost later on the productivity serious sheep pox occurs, and make sheep husbandry suffer huge loss.
The cause of disease SPV of primary disease belongs to Poxviridae, Capripoxvirus.This morphology of virus ovalize, its size is 115nm * 194nm, ovalize.This virus is a kind of virus of close epithelium, is present in a large number in pimple, abscess and the crust of skin, mucosa of disease sheep.Nasal mucosa secretions also contains virus, only at the initial stage of a disease, has virus to exist during body temperature rise in blood.SPV can be in the testicular cells of sheep, goat, calf etc. and nephrocyte culture and BHK21 cloned culture growth and breeding, can make cell produce CPE.General cell culture can be found cytoplasmic inclusions at virus inoculation 3-4 days in cell, visible virion under the Electronic Speculum.On the chick chorioallantoic membrane of growing, also can breed.
Sheep pox is by indivedual sheep morbidities at first, spreads gradually later on full group.Primary disease is mainly by respiratory tract infection, and virus also can be invaded body by skin or the mucosa of damage.Feeding and management personnel, care implement, fur product, feedstuff, pad grass and epizoa etc. all can become the medium of propagation.In natural situation, sheep pox betides sheep, can not infect to goat or other domestic animal.Fine-wool sheep has higher susceptibility than coarse-wooled sheep, and the state of an illness is also heavy than the latter.
The more aged sheep of lamb is responsive, and case fatality rate is also high.The gestation ewe easily causes miscarriage.The factors such as primary disease is mainly popular at the beginning of last month of spring in winter, and weather severe cold, sleet, frost, hay and feeding and management are bad all help the generation of primary disease and increase the weight of the state of an illness.
Primary disease average out to incubation period 6-8 days.Sick sheep fervescence is to 41-42 ℃, poor appetite, and lassitude, the conjunctiva flushing has serosity or purulent secretion to flow out from the nostril, breathing and pulse speedup.Approximately after 1-4 days, send out pox.Varioliform exanthema is multiple is born in the few hair of a skin part, as around the lower limb, on lip, nose, cheek, extremity and tail inboard, labia, breast, scrotum and the foreskin.Begin to be erythema, form pimple after 1-2 days, outstanding skin surface, pimple increases gradually subsequently, becomes canescence or pale red, hemispheric Boss.Tuberosity is becoming vesicle within these few days, and the vesicle content plays the primary image lymph fluid, after become suppurative liquid, if without secondary infection then become brown crust piece at several days inner dryings.The crust piece comes off and leaves over an erythema, and rear color is thin out gradually
Virus has special affinity to skin and mucomembranous epithelial cell, no matter pass through the virus which kind of route of infection is invaded body, all pass through blood and arrive skin and mucosa, in epithelial cell, breed, the specific varioliform exanthema that causes a series of inflammatory process and occur, the i.e. pathological processes such as pimple, vesicle, pustule and incrustation.
The characteristic pathological changes of primary disease is varioliform exanthema to occur at positions such as throat, trachea, lung and fourth stomaches.At the flat canescence varioliform exanthema that varying in size appears in the mucosas such as gastral lip, esophagus, gastrointestinal, wherein some surperficial ulceration forms erosion and ulcer, and particularly Mucosa of lip and gastric mucosa surface are more obvious.But tunica mucosa tracheae and other organa parenchymatosum, such as mucosa or the flat or hemispheric tuberositys of the next formation canescence of peplos such as heart, kidneys, particularly the pathological changes of lung is very similar to adenoma, mostly occur on the surface of lung, tangent plane is homogeneous, but very hard, quantity is indefinite, and character is then consistent.Visible congested and edema etc. sometimes around this focus.
Usually use 0.1% potassium permanganate solution to shampoo disease sheep affected part or wash disease sheep affected part with light salt brine to the treatment of primary disease, then embrocate with iodine glycerol, but said method can only be alleviated the body surface symptom of sheep pox, can not fundamentally treat sheep pox.
Summary of the invention
In order to overcome above-mentioned deficiency, the invention provides a kind of Chinese medicine composition for the treatment of sheep pox evident in efficacy.
Concrete technical scheme of the present invention is: a kind of Chinese medicine composition for the treatment of sheep pox, and count by weight by following component and form: Flos Lonicerae 1-120 part, Flos Chrysanthemi Indici 1-120 part, Herba Taraxaci 1-120 part, Herba Violae 1-120 part, Radix Scutellariae 1-115 part, Radix Isatidis 1-115 part, Rhizoma Cimicifugae 1-110 part, Radix Arnebiae (Radix Lithospermi) 1-115 part, the sub-1-110 part of Radix Semiaquilegiae, Radix Glycyrrhizae 1-110 part.
A kind of Chinese medicine composition for the treatment of sheep pox is counted by weight by following component and is formed: 20 parts of Flos Loniceraes, 20 parts of Flos Chrysanthemi Indicis, 20 parts of Herba Taraxacis, 20 parts of Herba Violaes, 15 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 10 parts of Rhizoma Cimicifugaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 10 parts of Radix Semiaquilegiae, 10 parts in Radix Glycyrrhizae.
During treatment, with above-mentioned Chinese medicine composition and water, mix in the 1:4-20 ratio in parts by weight, decoction, serve on for 1 ~ 2 week at 1 dose of every sheep every day.
Certain county is the cold sheep of the little tail of a large amount of introductions from the strange land, and sheep pox is distributed when the part small towns.Clinical symptoms according to the morbidity sheep: at first find indivedual sheep morbidities after the introduction, involve full group after 1 ~ 2 week.Sick just fervescence to 41 ℃ ~ 42 ℃, conjunctiva flushing, nose stream mucus.Send out pox behind 1 ~ 4d, around the sick sheep eye, the macule of the inboard skin generation Semen phaseoli radiati size without hair or few hair of lip, cheek, the wing of nose, vaginal orifice, breast, root of the tail section and extremity, outstanding skin surface.Becoming vesicle through 2 ~ 3d macule, some vesicles develop into pustule, form at last the crust piece.Severe patient all can be seen or touch at the skin of breast, abdomen and extremity and swells in the harder tuberosity of skin surface Semen Pisi sativi size, dyspnea, and the sick sheep that has often dies from secondary infection.It is little and rare that the sheep of mild symptoms only sends out pox, and by the pimple spontaneous recovery of forming a scab without suppuration, the course of disease is about 10d.Some morbidity sheep only merges generation conjunctivitis, vesicular stomatitis, laryngitis, viral pneumonia etc.
Block the morbidity flock of sheep, isolate the disease sheep, forbid that the disease sheep is mobile.To contacting the disease sheep but the sheep that does not show clinical symptoms only quarantine, be diagnosed as behind the 1d and do not infect ovination sheep pox vaccine.
Sick sheep is adopted Chinese medicine of the present invention, and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs is treated 152, cures 151, and is evident in efficacy.
The present invention adopts the method for the dialectical treatment of Chinese veterinarian, provide Flos Lonicerae in the scheme to have the effect of heat-clearing and toxic substances removing; Flos Chrysanthemi Indici has the effect of heat-clearing and toxic substances removing, detumescence; Herba Taraxaci has the effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds; Herba Violae has the effect of heat-clearing and toxic substances removing, removing heat from blood detumescence; Radix Scutellariae has heat clearing and damp drying, the effect of removing pathogenic heat from blood and toxic substance from the body; Radix Isatidis has the effect of heat-clearing and toxic substances removing, removing heat from blood detumescence; Rhizoma Cimicifugae has the effect of heat-clearing and toxic substances removing, tonifying Qi and lifting yang; Radix Arnebiae (Radix Lithospermi) has removing heat from blood, the effect of rash of invigorating blood circulation, detoxify; The effect that Radix Semiaquilegiae has detoxifcation, invigorates blood circulation, subsides a swelling; Flos Lonicerae, Flos Chrysanthemi Indici, Herba Taraxaci, Herba Violae and Radix Scutellariae, Radix Isatidis, Rhizoma Cimicifugae, Radix Arnebiae (Radix Lithospermi), Radix Semiaquilegiae, Radix Glycyrrhizae are used jointly, can effectively treat the contagious disease that is caused by sheep pox virus--sheep pox, effectively alleviate it at whole skin, sometimes also at the typical varioliform exanthema of mucosa appearance, significantly reduce because the higher mortality rate that the heating of sick sheep causes.
The specific embodiment
The invention will be further described below by specific embodiment, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
16 in the cold sheep of 18 little tails that Zhang raises sheep pox occur, by scheme determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs provided by the invention, all cure.Wherein, have in the ill sheep the cold sheep of 1 little tail and produce 23 the monthly age lamb fall ill simultaneously, disease show speckle varioliform exanthema spreads all over whole body, cephalledema, the llama dyspnea, diet is for waste absolutely, sleeping ground does not rise, there is varioliform exanthema in the oral cavity.2 lamb symptoms of producing are lighter, the excrement of having loose bowels.First sick sheep oral cavity is washed with 0.1% potassium permanganate liquid during treatment, and is embrocated iodine glycerol at varioliform exanthema, gavage Chinese medicine of the present invention:
Flos Lonicerae 25g, Flos Chrysanthemi Indici 25g, Herba Taraxaci 25g, Herba Violae 25g, Radix Scutellariae 20g, Radix Isatidis 20g, Rhizoma Cimicifugae 15g, Radix Arnebiae (Radix Lithospermi) 15g, the sub-15g of Radix Semiaquilegiae, Radix Glycyrrhizae 15g; Above-mentioned Chinese medicine composition and water is in parts by weight, adds in the 1:10 ratio, after being decocted in water for oral dose, 1 dose of every sheep every day, serve on for 1 ~ 2 week.Clinical symptoms is faded after the medication, the walking that feels one's feet in 3 days, drink liquid food, 7 days.
Above preferred embodiment of the present invention is had been described in detail, but described content only is preferred embodiment of the present invention, can not be considered to be used to limiting practical range of the present invention.All equalizations of doing according to the present patent application scope change and improve etc., all should still belong within the patent covering scope of the present invention.

Claims (2)

1. Chinese medicine composition for the treatment of sheep pox is characterized in that counting by weight by following component and forms: Flos Lonicerae 1-120 part, Flos Chrysanthemi Indici 1-120 part, Herba Taraxaci 1-120 part, Herba Violae 1-120 part, Radix Scutellariae 1-115 part, Radix Isatidis 1-115 part, Rhizoma Cimicifugae 1-110 part, Radix Arnebiae (Radix Lithospermi) 1-115 part, the sub-1-110 part of Radix Semiaquilegiae, Radix Glycyrrhizae 1-110 part.
2. Chinese medicine composition for the treatment of sheep pox is characterized in that counting by weight by following component and forms: 20 parts of Flos Loniceraes, 20 parts of Flos Chrysanthemi Indicis, 20 parts of Herba Taraxacis, 20 parts of Herba Violaes, 15 parts of Radix Scutellariaes, 15 parts of Radix Isatidis, 10 parts of Rhizoma Cimicifugaes, 15 parts of Radix Arnebiae (Radix Lithospermi)s, 10 parts of Radix Semiaquilegiae, 10 parts in Radix Glycyrrhizae.
CN201210425432.8A 2012-10-31 2012-10-31 Traditional Chinese medical composition for treatment of sheep pox Expired - Fee Related CN102895418B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599260A (en) * 2013-11-19 2014-02-26 山东绿州动物药业有限公司 Preparation method of heat-clearing, toxicity-removing, antibacterial and antiviral traditional Chinese medicine oral liquid for birds
CN104398685A (en) * 2014-11-25 2015-03-11 李兴如 Traditional Chinese medicine composition for treating goatpox and preparation and use method of traditional Chinese medicine composition
CN104068283B (en) * 2014-07-16 2016-04-20 山东新希望六和集团有限公司 For preventing and treating the feed of sheep pox, Chinese medicine composition, preparation method and application
CN106377578A (en) * 2016-11-30 2017-02-08 刘吴阳 Feed additive applied to sheep pox disease

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101683116A (en) * 2008-09-23 2010-03-31 张松灿 Pure traditional Chinese medicine feed additive

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101683116A (en) * 2008-09-23 2010-03-31 张松灿 Pure traditional Chinese medicine feed additive

Non-Patent Citations (1)

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Title
王殿君: "绵羊痘的防治", 《中兽医医药杂志》, no. 1, 31 January 1995 (1995-01-31), pages 47 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103599260A (en) * 2013-11-19 2014-02-26 山东绿州动物药业有限公司 Preparation method of heat-clearing, toxicity-removing, antibacterial and antiviral traditional Chinese medicine oral liquid for birds
CN104068283B (en) * 2014-07-16 2016-04-20 山东新希望六和集团有限公司 For preventing and treating the feed of sheep pox, Chinese medicine composition, preparation method and application
CN104398685A (en) * 2014-11-25 2015-03-11 李兴如 Traditional Chinese medicine composition for treating goatpox and preparation and use method of traditional Chinese medicine composition
CN104398685B (en) * 2014-11-25 2018-04-27 子长县旺元农牧业有限公司 A kind of Chinese medicine composition and its preparation and application for treating goatpox
CN106377578A (en) * 2016-11-30 2017-02-08 刘吴阳 Feed additive applied to sheep pox disease

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