CN102416115B - Traditional Chinese medicine composition for treating herpes progenitalis - Google Patents
Traditional Chinese medicine composition for treating herpes progenitalis Download PDFInfo
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- CN102416115B CN102416115B CN 201110378361 CN201110378361A CN102416115B CN 102416115 B CN102416115 B CN 102416115B CN 201110378361 CN201110378361 CN 201110378361 CN 201110378361 A CN201110378361 A CN 201110378361A CN 102416115 B CN102416115 B CN 102416115B
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Abstract
The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating herpes progenitalis. The traditional Chinese medicine composition for treating herpes progenitalis comprises: by weight, 5 to 15 parts of radix gentianae, 5 to 15 parts of cape jasmine fruit, 5 to 15 parts of baical skullcap root, 5 to 15 parts of radix bupleuri, 5 to 15 parts of raw rehmannia root, 5 to 15 parts of Chinese angelica, 10 to 20 parts of milkvetch root, 10 to 20 parts of Chinese yam, 10 to 20 parts of Indian buead, 5 to 15 parts of plantain seed, 5 to 15 parts of akebia stem, 25 to 35 parts of raw coix seed, 10 to 20 parts of honeysuckle flower, 25 to 35 parts of dandelion, 25 to 35 parts of herba violae, 25 to 35 parts of isatis root and 3 to 9 parts of raw licorice. The traditional Chinese medicine composition for treating herpes progenitalis has the functions of clearing heat and disinhibiting dampness, and nourishing yin and removing toxins, can realize simultaneous treatment on principal and subordinate symptoms of herpes progenitalis, and can greatly reduce a herpes progenitalis recurrence rate.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly a kind of Chinese medicine composition for the treatment of genital herpes.
Background technology
Genital herpes is common one of the disease that spreads through sex intercourse of China.Infecting institute by herpes simplex virus (HSV) causes.It is HSV-1 and HSV-2 that herpes simplex virus is divided into amphitypy.HSV-2 then is the main pathogens (90%) of genital herpes, is present in the transudate, prostate juice, cervix uteri, vaginal secretion of skin and mucosal injury, mainly infects by sexual intercourse, causes primary genitalia herpes.After primary genitalia herpes disappears, remaining virus is hidden in the hiding in sacral ganglia along the neuraxon for a long time through peripheral nerve, when Abwehrkraft des Koepers reduce or some motivating factor as generate heat, suffer from cold, effects such as infection, menstruation, gastrointestinal dysfunction, wound time, can make the activated viral of hiding in the body and recur.Genital herpes mostly occurs at the intersection of skin and mucosa, local skin was slightly rubescent before this, then send the phlysis of picture needle point size in groups, the sensation of slightly itching and burning is arranged, form brown crust with regard to exsiccation after several days, slight pigmentation is arranged after crust comes off, but also disappear soon, whole average weeks of the course of disease, but common recurrence.Female patients is multiple to be born in around labia, the anus, vagina, causes cervicitis or metritis but about 90% patient can invade cervix uteri simultaneously; Multiple glans penis, coronary sulcus, urethral orifice or the body of penis of being born in of male patient sometimes can concurrent urethritis.
For the treatment of genital herpes, divide at present general treatment, antiviral therapy and traditional Chinese medical herbal treatment, these treatments all are necessary.General treatment in fact is symptomatic treatment, and antiviral therapy is etiological treatment, and the curative effect of general treatment and antiviral therapy is unsatisfactory, the clinical symptoms that only can palliate a disease, easily recurrence.How traditional Chinese medical herbal treatment is by determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and treating both the principal and secondary aspects of a disease stops recurrence effectively.But the medicine of existing traditional Chinese medical herbal treatment genital herpes is also few, demands a kind of new and appearance that can effectively treat genital herpes Chinese medicine urgently.
Summary of the invention
For overcoming the deficiencies in the prior art part, the object of the present invention is to provide a kind of Chinese medicine composition for the treatment of genital herpes evident in efficacy.
For achieving the above object, the technical scheme taked of the present invention is as follows:
A kind of Chinese medicine composition for the treatment of genital herpes is made by the crude drug of following portions by weight: 5 ~ 15 parts of Radix Gentianae, 5 ~ 15 parts of Fructus Gardeniaes, 5 ~ 15 parts of Radix Scutellariaes, 5 ~ 15 parts of Radix Bupleuri, 5 ~ 15 parts of Radix Rehmanniae, 5 ~ 15 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of the Radixs Astragali, 10 ~ 20 parts of Rhizoma Dioscoreaes, 10 ~ 20 parts in Poria, 5 ~ 15 parts of Semen Plantaginiss, 5 ~ 15 parts of Caulis Akebiaes, 25 ~ 35 parts of Semen Coicis, 10 ~ 20 parts of Flos Loniceraes, 25 ~ 35 parts of Herba Taraxacis, 25 ~ 35 parts of Herba Violaes, 25 ~ 35 parts of Radix Isatidis, 3 ~ 9 parts of Radix Glycyrrhizae.
Further, the parts by weight of described crude drug are preferably: 10 parts of Radix Gentianae, 10 parts of Fructus Gardeniaes, 10 parts of Radix Scutellariaes, 10 parts of Radix Bupleuri, 10 parts of Radix Rehmanniae, 10 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 15 parts in Poria, 10 parts of Semen Plantaginiss, 10 parts of Caulis Akebiaes, 30 parts of Semen Coicis, 15 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 30 parts of Herba Violaes, 30 parts of Radix Isatidis, 6 parts of Radix Glycyrrhizae.
Described Chinese medicine composition routinely technique is made decoct.
Pharmacology of the present invention: Radix Gentianae (Radix Gentianae): bitter, cold, return liver, gallbladder meridian, heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.Fructus Gardeniae (SHANZHIZI): bitter, cold, GUIXIN, lung, tri-jiao channel, pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Radix Scutellariae: bitter, cold, return lung, gallbladder, spleen, large intestine, small intestine meridian, heat clearing and damp drying, eliminating fire and detoxication.Radix Bupleuri: bitter, be slightly cold, return liver, gallbladder meridian, reconciling superficies and interior, soothing the liver, yang invigorating.Radix Rehmanniae (Radix Rehmanniae): sweet, bitter, cold in nature, GUIXIN, liver, lung meridian, promote the production of body fluid at clearing away heat and cooling blood, yin nourishing.Radix Angelicae Sinensis: sweet, hot, warm, return liver, the heart, spleen channel, enrich blood invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.The Radix Astragali: sweet, warm, return lung, spleen channel, invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Rhizoma Dioscoreae: sweet, flat, return spleen, lung, kidney channel, spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Poria: sweet, light, flat, GUIXIN, lung, spleen, kidney channel, promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.Semen Plantaginis: sweet, be slightly cold, return liver, kidney, lung, small intestine meridian, clearing away heat and promoting diuresis, eliminating dampness by diuresis is treating stranguria, make eye bright, eliminate the phlegm.Caulis Akebiae: bitter, be slightly cold GUIXIN, small intestinal, urinary bladder channel, clearing away heart-fire, diuresis.Semen Coicis (Semen Coicis): sweet, light, cool, return spleen, stomach, lung meridian, spleen invigorating eliminating dampness by diuresis, eliminating impediment antidiarrheal, clearing away heat and discharging pus.Flos Lonicerae (Flos Lonicerae): sweet, cold, return lung, the heart, stomach warp, heat-clearing and toxic substances removing, wind-heat dissipating.Herba Taraxaci: bitter, sweet, cold, return liver, stomach warp, heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.Herba Violae: bitter, hot, cold, GUIXIN, Liver Channel, heat-clearing and toxic substances removing, removing heat from blood detumescence.Radix Isatidis: bitter, cold, GUIXIN, stomach warp, heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.Radix Glycyrrhizae: sweet, flat, GUIXIN, lung, spleen, stomach warp, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.More than the mutual compatibility of all medicines, play altogether the effect of eliminating damp-heat, YIN nourishing detoxifcation.
Medicine of the present invention has the effect of eliminating damp-heat, YIN nourishing detoxifcation, and the treating both the principal and secondary aspects of a disease genital herpes is difficult for recurrence after the treatment.
The specific embodiment
Embodiment 1
A kind of Chinese medicine composition for the treatment of genital herpes takes by weighing following crude drug: Radix Gentianae 10g, Fructus Gardeniae 10g, Radix Scutellariae 10g, Radix Bupleuri 10g, Radix Rehmanniae 10g, Radix Angelicae Sinensis 10g, Radix Astragali 15g, Rhizoma Dioscoreae 15g, Poria 15g, Semen Plantaginis 10g, Caulis Akebiae 10g, Semen Coicis 30g, Flos Lonicerae 15g, Herba Taraxaci 30g, Herba Violae 30g, Radix Isatidis 30g, Radix Glycyrrhizae 6g.
Therapeutic Method: every day potion, routine is decocted in water for oral dose, and sooner or later services once, 20 days is a course for the treatment of, is used in conjunction 1 ~ 2 course for the treatment of.
Embodiment 2
A kind of Chinese medicine composition for the treatment of genital herpes takes by weighing following crude drug: Radix Gentianae 5g, Fructus Gardeniae 5g, Radix Scutellariae 5g, Radix Bupleuri 5g, Radix Rehmanniae 5g, Radix Angelicae Sinensis 5g, Radix Astragali 10g, Rhizoma Dioscoreae 10g, Poria 10g, Semen Plantaginis 5g, Caulis Akebiae 5g, Semen Coicis 25g, Flos Lonicerae 10g, Herba Taraxaci 25g, Herba Violae 25g, Radix Isatidis 25g, Radix Glycyrrhizae 3g.
Therapeutic Method: with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition for the treatment of genital herpes takes by weighing following crude drug: Radix Gentianae 15g, Fructus Gardeniae 15g, Radix Scutellariae 15g, Radix Bupleuri 15g, Radix Rehmanniae 15g, Radix Angelicae Sinensis 15g, Radix Astragali 20g, Rhizoma Dioscoreae 20g, Poria 20g, Semen Plantaginis 15g, Caulis Akebiae 15g, Semen Coicis 35g, Flos Lonicerae 20g, Herba Taraxaci 35g, Herba Violae 35g, Radix Isatidis 35g, Radix Glycyrrhizae 9g.
Therapeutic Method: with embodiment 1.
Clinical trial
One, physical data
From year August in January, 2009 to 2011, accept patients with genital herpes totally 36 examples for medical treatment.Wherein, male 20 examples, women 16 examples, 25 ~ 40 years old age.
Two, diagnostic criteria
1, contact history has unmarried property contact history or spouse to infect history.
2, clinical manifestation
This disease is caused by herpes simplex virus, can be divided into two kinds of clinical manifestations of constitutional and recurrent.
2.1 primary genitalia herpes
2.1.1 3～14 days incubation periods.
2.1.2 the phlysis that group variety is arranged or be dispersed in around external genitalia or the anus, ulceration forms erosion or ulcer after 2～4 days, conscious pain.
2.1.3 the normal enlargement of inguinal lymph nodes has tenderness.
2.1.4 the patient often has heating, headache, the General Symptoms such as weak.
2.1.5 about 2～3 weeks of the course of disease.
2.2 recurrent genital herpes
Former skin lesion rear erythra that disappears is shown effect repeatedly, and recurrent genital herpes is light than constitutional General Symptoms and skin lesion, and the course of disease is shorter.
Burn feeling is arranged, prickling sensation or paraesthesia 2.2.1 play the front part of rash.
2.2.2 group variety phlysis around external genitalia or the anus, very fast ulceration forms erosion or fester, and subjective symptoms is lighter.
2.2.3 the course of disease 7～10 days.
Three, Therapeutic Method
Embodiment 1 prescription, every day potion, routine is decocted in water for oral dose, and sooner or later services once, 20 days is a course for the treatment of, is used in conjunction 1 ~ 2 course for the treatment of.
Four, efficacy assessment standard
Cure: the affected part skin lesion disappears fully, other clinical symptom disappearance, nothing recurrence in half a year.
Effectively: the affected part skin lesion disappears fully, other clinical symptom disappearance, and recurrence is 1 ~ 2 time in half a year.
Invalid: before affected part skin lesion and other clinical symptoms are treated without significant change or add severe one.
Five, statistical result
Cure 22 examples, effective 13 examples, invalid 1 example, total effective rate 97.2%.
Model case
Case 1: unclean sexual life history 26 years old, once occured in Mr. Huang before one week of patient's readme, found before 2 days that foreskin, glans penis length have more than 10 slight and red pimples of pruritus, after become phlysis, pruritus, causalgia, urethral irritation, urgent micturition, frequent micturition, not to the utmost dripping are with being diagnosed as genital herpes.Take course for the treatment of of the embodiment of the invention 1 medicine, skin lesion disappears more than 70%, and other clinical malaise symptoms also is clearly better, and takes again a course for the treatment of, and skin lesion disappears fully, and the also complete obiteration of other clinical symptoms was not followed up a case by regular visits to after half a year and recurred.
Case 2: Mrs Gao, 32 years old, the self-induction labia was scorching hot, the phlysis that perusal has group variety or is dispersed in, ulceration forms erosion or ulcer after 2～4 days, and mild pain is arranged, and outbreak once is diagnosed as genital herpes during every menstruation.Take course for the treatment of of the embodiment of the invention 2 medicines, skin lesion and other clinical symptom disappearance were not followed up a case by regular visits to after half a year and were recurred.
Case 3: Mr. Zhang, 40 years old, sexual behaviour occurs with the bar girl, after the about week, cluster causalgia herpes occurs at the coronary sulcus position, ulceration after 2 days is the strip erosion, a small amount of purulent secretion is arranged, and the both sides inguinal lymph nodes swells and ache.Once went to many hospitalizes, all be diagnosed as genital herpes, but curative effect was unsatisfactory, always took a turn for the better to some extent after the treatment but again and again outbreak.After upon somebody's introduction, come here.Take course for the treatment of of the embodiment of the invention 3 medicines, skin lesion disappears half, and other clinical malaise symptoms disappears, take again a course for the treatment of after, skin lesion disappears fully, does not follow up a case by regular visits to after half a year and recurs.
Claims (2)
1. Chinese medicine composition for the treatment of genital herpes is characterized in that being made by the crude drug of following portions by weight:
5 ~ 15 parts of Radix Gentianae, 5 ~ 15 parts of Fructus Gardeniaes, 5 ~ 15 parts of Radix Scutellariaes, 5 ~ 15 parts of Radix Bupleuri, 5 ~ 15 parts of Radix Rehmanniae, 5 ~ 15 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of the Radixs Astragali, 10 ~ 20 parts of Rhizoma Dioscoreaes, 10 ~ 20 parts in Poria, 5 ~ 15 parts of Semen Plantaginiss, 5 ~ 15 parts of Caulis Akebiaes, 25 ~ 35 parts of Semen Coicis, 10 ~ 20 parts of Flos Loniceraes, 25 ~ 35 parts of Herba Taraxacis, 25 ~ 35 parts of Herba Violaes, 25 ~ 35 parts of Radix Isatidis, 3 ~ 9 parts of Radix Glycyrrhizae.
2. the Chinese medicine composition for the treatment of genital herpes as claimed in claim 1 is characterized in that the parts by weight of described crude drug are:
10 parts of Radix Gentianae, 10 parts of Fructus Gardeniaes, 10 parts of Radix Scutellariaes, 10 parts of Radix Bupleuri, 10 parts of Radix Rehmanniae, 10 parts of Radix Angelicae Sinensis, 15 parts of the Radixs Astragali, 15 parts of Rhizoma Dioscoreaes, 15 parts in Poria, 10 parts of Semen Plantaginiss, 10 parts of Caulis Akebiaes, 30 parts of Semen Coicis, 15 parts of Flos Loniceraes, 30 parts of Herba Taraxacis, 30 parts of Herba Violaes, 30 parts of Radix Isatidis, 6 parts of Radix Glycyrrhizae.
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| CN 201110378361 CN102416115B (en) | 2011-11-24 | 2011-11-24 | Traditional Chinese medicine composition for treating herpes progenitalis |
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| CN105055677A (en) * | 2015-07-28 | 2015-11-18 | 吴斌 | Traditional Chinese medicine for treating genital herpes |
| CN108295223A (en) * | 2018-04-25 | 2018-07-20 | 乐山市市中区驳骨堂中医药研究所 | A kind of drug and preparation process for treating virus infected herpes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2003221315A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use to be used for hair growth |
| CN1753682A (en) * | 2003-01-16 | 2006-03-29 | 利盛私人有限公司 | The herbal-composition that is used for prostatosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2003221315A (en) * | 2002-01-25 | 2003-08-05 | Kunio Tsuji | Skin care preparation for external use to be used for hair growth |
| CN1753682A (en) * | 2003-01-16 | 2006-03-29 | 利盛私人有限公司 | The herbal-composition that is used for prostatosis |
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