CN103623286B - A kind of Chinese herbal medicine for treating genital herpes - Google Patents

Abstract

The invention discloses a Chinese herbal medicine for treating genital herpes. Made from Chinese herbal medicine. The Chinese herbal medicine has the effects of cooling blood and detoxification, promoting dampness and turbidity, and nourishing yin and promoting body fluid. It is suitable for the treatment of genital herpes, and has the advantages of precise compatibility, quick effect, high cure rate, low recurrence rate, simple preparation and low cost. At the same time, due to its The medicinal materials of each component are pure natural plants, so the prescription does not have any toxic and side effects and is safe to take.

Description

A kind of Chinese herbal medicine for treating genital herpes

technical field

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a Chinese herbal medicine with definite curative effect for treating genital herpes.

Background technique

Genital herpes (GH) is a chronic inflammatory recurrent sexually transmitted disease caused by herpes simplex virus (HSV) invading the skin and mucous membranes of the genital area. HSV invades epithelial cells through tiny wounds in the skin and mucous membranes to replicate and multiply, causing a series of inflammatory reactions such as cell balloon deformation and necrosis, inflammatory cell invasion, and stimulating the body to produce corresponding immune responses. After the initial infection, the clinical manifestations are severe, and male patients tend to develop on the penis, glans, foreskin, etc.; female patients often appear on the vulva, perianal, cervix, and buttocks, with miliary papules or blisters, which can merge into sheets. In severe cases, there may be ulceration and erosion, accompanied by abnormal sensations such as pain, burning, and itching. After the primary genital herpes subsides, the residual virus remains latent in the lumbosacral ganglia for a long time. When the body suffers from certain triggers or the resistance is reduced, the latent virus in the body can be activated to recur again, and the recurrence rate is as high as 50%-70%. The incidence of genital herpes in my country is on the rise. According to statistics, it has increased from 0.052/100,000 in 1991 to 1.93/100,000 in 1999, and has become the number one cause of genital ulcers. Once infected, the herpes simplex virus is carried for life and is prone to recurrent attacks. However, there is no specific treatment for this disease like syphilis and gonorrhea. It brings a series of psychological and physical troubles to patients and their families, and seriously affects the quality of life of patients.

The treatment of genital herpes is currently clinically divided into two methods: western medicine treatment and traditional Chinese medicine treatment. Western medicine often adopts antiviral and general symptomatic treatment, but the curative effect is not ideal. Although it can alleviate clinical symptoms, it is very easy to relapse and has many side effects. Genital herpes belongs to the category of "genital heat sore" and "yin malnutrition" in traditional Chinese medicine. Clinically, clearing heat and detoxifying, invigorating the spleen and dampness, nourishing qi and nourishing yin are the main treatment methods, and the combination of drugs is selected to achieve the therapeutic purpose. For the treatment of genital herpes and the effective prevention of recurrence, it has a good curative effect compared with Western medicine. Using traditional Chinese medicine to treat genital herpes has become the focus of medical circles. However, there are not many pure traditional Chinese medicines for treating genital herpes, and the curative effect is average. Patients are in urgent need of a pure Chinese medicine preparation that can effectively treat genital herpes. To appear, to relieve their pain.

Contents of the invention

The object of the present invention is to provide a traditional Chinese medicine for oral administration with low cost, simple preparation, remarkable curative effect, treating both symptoms and root causes, not easy to relapse, and less toxic and side effects.

The technical scheme of the present invention is: a Chinese herbal medicine for treating genital herpes, which is composed of the following raw materials in proportion by weight: 10-15 parts of Gentiana, 10-15 parts of Scutellaria baicalensis, 10-15 parts of Bupleurum, 15-15 parts of Radix Radix 30 parts, Smilax 15-20 parts, Plantago 10-15 parts, Alisma 10-15 parts, Raw barley 15-30 parts, Rehmannia 15-20 parts, Purslane 15-20 parts, Scrophulariaceae 10- 15 parts, 6-10 parts of licorice.

In the pharmaceutical prescription of the present invention, the functions and indications of all raw materials are respectively:

Radix Gentianae: bitter in nature and flavor, cold. Return liver, gallbladder channel. It has the effects of clearing away heat and dampness, purging liver and gallbladder fire. Cure mainly damp-heat jaundice, vaginal swelling, vaginal itching, vaginal discharge, eczema and itching; liver fire headache, conjunctival congestion and deafness, hypochondriac pain and bitter mouth; convulsions and convulsions.

Scutellaria baicalensis: bitter in nature and flavor, cold. Return lung, gallbladder, spleen, stomach, large intestine, small intestine channel. It has the effects of clearing away heat and dampness, purging fire and detoxification, stopping bleeding, and preventing miscarriage. Cure mainly damp-warm, heat-dampness, chest tightness and nausea, damp-heat fullness, jaundice and dysentery; cough due to lung heat, high fever and polydipsia; vomiting of blood heat at the nose; carbuncle sores; fetal movement embolism.

Bupleurum: bitter in nature and flavor, pungent, slightly cold. Return liver, gallbladder channel. It has the effects of relieving the exterior and reducing fever, soothing the liver and relieving depression, and promoting yang qi. Indications: superficial syndrome fever, shaoyang syndrome; stagnation of qi due to liver depression; qi deficiency and subsidence, organ prolapse and other diseases.

Radix Radix: nature and flavor are bitter, cold. GUIXIN, Stomach Meridian. It has the effects of clearing away heat and detoxification, cooling blood and relieving sore throat. Indications for fever due to exogenous pathogenic factors, early onset of febrile disease, sore throat; febrile toxins with plaques, mumps, erysipelas, carbuncle and sores.

Smilax Smilax: sweet in nature and flavor, light, flat. Return liver, stomach warp. With detoxification, dehumidification, Tongli joints and other effects. Cure mainly red bayberry sores, limb spasms; stranguria leucorrhea, eczema itching; carbuncle sores embolism.

Fructus Plantaginis: sweet in nature and slightly cold in flavor. Return liver, kidney, lung, small intestine channel. It has the effects of inducing diuresis and treating stranguria, expelling dampness and stopping diarrhea, improving eyesight and eliminating phlegm. Indications for stranguria syndrome, edema; diarrhea; conjunctival congestion, swelling, pain, dark eyes, nebula; phlegm-heat cough embolism.

Alisma: sweet in nature and cold in flavor. Return kidney, urinary bladder channel. It has the effects of promoting diuresis, expelling dampness, and expelling heat. Indications for edema, dysuria, diarrhea; stranguria, nocturnal emission embolism.

Raw barley: sweet, light and cool in nature and flavor. Return spleen, stomach, lung meridian. It has diuresis and dampness expelling, invigorating the spleen, eliminating numbness, effects such as clearing away heat and evacuating pus. Indications for edema, dysuria, beriberi; diarrhea due to spleen deficiency; contraction of dampness arthralgia; pulmonary abscess, intestinal abscess and other diseases.

Habitat: sweet, bitter, cold in nature and flavor. GUIXIN, liver, kidney channel. It has the effects of clearing away heat and cooling blood, nourishing yin and promoting body fluid. Indications for treating heat such as camping blood, crimson tongue, polydipsia, macule and vomiting of nosebleeds; yin deficiency and internal heat, bone steaming and labor heat; fluid wound thirst, internal heat and quenching thirst, intestinal dryness and constipation.

Purslane: sour in nature and flavor, cold. Return liver, large intestine channel. It has the functions of clearing heat and detoxifying, cooling blood and stopping bleeding, and stopping dysentery. Indications heat-toxin blood dysentery; heat-toxin sores; metrorrhagia, hematochezia embolism.

Radix Scrophulariae: nature and flavor are sweet, bitter, salty, slightly cold. Return lung, stomach, kidney channel. It has the effects of clearing heat and cooling blood, purging fire and detoxifying, nourishing yin and so on. Indications of warm evil entering the camp, inward pericardium. Warm and poisonous spots; febrile disease damages yin, fluid damages constipation, bone steaming and labor cough embolisms.

Licorice: sweet in nature and flavor, flat. GUIXIN, lung, spleen, stomach warp. It has the effects of invigorating the spleen and replenishing qi, eliminating phlegm and relieving cough, relieving spasm and relieving pain, clearing away heat and detoxification, and harmonizing various medicines. Indications for deficiency of heart-qi, intermittent pulse, palpitation, deficiency of spleen-qi, cough and asthma, epigastric abdomen, acute pain of extremities, heat-toxin sores, sore throat, drug and food poisoning and other diseases.

The theory of traditional Chinese medicine believes that genital herpes is caused by exogenous damp-heat and filthy pathogens, heat-wrapped damp pathogens, entering the blood system, injuring the liver and spleen, affecting the circulation of qi and blood, and causing pathological products such as phlegm-heat and turbidity to enter the perineum. Damp-heat toxin accumulates in the liver and gallbladder, injects in the genitals, hot and damp, and damp-heat accumulates and steams on the skin surface, resulting in skin herpes; excessive heat damages yin and consumes qi, dampness is yin evil, damages yang, and damages the liver and spleen , clinically often form the persistent disease of positive and false, evil love, and the mixture of deficiency and excess. Therefore, the core pathogenesis of this disease is: heat wraps damp evil, enters the blood system, enters the liver and gallbladder, and injects dampness and poison through the liver meridian, enters the genitals, and steams the skin. Treatment principles should be based on cooling blood and detoxification, promoting dampness and turbidity, and nourishing yin and promoting body fluid. The herbal medicine of gentian in the prescription is bitter in nature and cold in the liver and gallbladder meridian. Bitterness can dry dampness, coldness can clear away heat, enter the liver meridian, and the liver stores blood, so it can clear away heat and dampness, cool blood and detoxify, that is, relieve the toxic heat of the liver, gallbladder and blood, and benefit the liver. Through damp and hot, two are good at its merits, so it is the king's medicine. Banlangen is bitter and cold in medicine, returns to the heart and stomach meridian, cools blood and heat, detoxifies and reduces swelling; , liver and kidney meridians, clearing heat and cooling blood, nourishing yin and promoting body fluid; Scrophulariaceae is sweet, bitter, salty and slightly cold in nature, and returns to lung, stomach and kidney meridian, clearing heat and cooling blood, detoxifying and purging fire, nourishing yin and promoting body fluid, the above-mentioned medicines help Gentiana detoxifies heat with cooling blood, so it is a ministerial drug. Scutellaria baicalensis is bitter and cold in nature, returns to the lung, gallbladder, spleen, stomach, large intestine and small intestine meridian, clears heat and dampness, purifies fire and detoxifies, and relieves damp heat in the upper burner; licorice is sweet and flat in nature, returns to the heart, lung, spleen and stomach meridian, clears away heat Detoxification, neutralizes phlegm, raw barley is sweet, light, and cool in nature, and returns to the spleen, stomach, and lung meridian. The combination of various medicines removes damp heat and turbid phlegm in the middle burner; Alisma diarrhea is sweet and cold in nature, returns to kidney, stranguria, oozes dampness and resolves phlegm; As a result, the above-mentioned medicines remove the dampness of the lower burner and help Gentiana to dehumidify and detoxify, so they are also ministerial medicines. Liver likes dredging and depressing depression, filthy turbidity and internal stagnation, which is the discomfort of the liver and gallbladder, and the medicine of bitter cold and diarrhea is used to avoid damage to the liver and gallbladder. The meridian, relieves the exterior and reduces fever, elevates yang qi, regulates liver qi, soothes the liver and relieves depression, introduces various medicines to act on the liver and gallbladder meridian, and plays a role in assisting with licorice. The combination of various medicines has the effects of cooling blood and detoxification, promoting dampness and turbidity, nourishing yin and promoting body fluid, which is in line with the TCM pathogenesis of genital herpes.

Modern pharmacological research proves:

Gentian grass and gentian water infusion have different degrees of inhibitory effects on skin fungi such as Trichophyton gypsum and Nocardia star, and also have inhibitory effects on Leptospira, Pseudomonas aeruginosa, Proteus, and Salmonella typhi; The gentiopicroside contained in it has anti-inflammatory, liver-protecting and anti-malarial effects; Antibody generation and stomach invigorating effect.

Scutellaria baicalensis, Scutellaria baicalensis decoction in vitro on Shigella, diphtheria bacillus, Pseudomonas aeruginosa, typhoid bacillus, paratyphoid bacillus, Proteus, Staphylococcus aureus, hemolytic streptococcus, pneumococcus, meningococcus, Vibrio cholerae, etc. There are different degrees of inhibitory effect; baicalin has a relieving effect on the allergic contraction of the isolated trachea of guinea pigs and the allergic asthma of the whole animal, and has a synergistic effect with ephedrine, which can reduce the permeability of mouse ear capillaries; this product It also has antipyretic, antihypertensive, sedative, liver-protecting, choleretic, inhibiting intestinal peristalsis, lowering blood fat, anti-oxidation, regulating cAMP level, anti-tumor effects; Scutellaria baicalensis water extract has inhibitory effect on prostaglandin biosynthesis.

Bupleurum, Bupleurum pharmacological effects have a wide range of central inhibitory effects such as sedation, stability, analgesia, antipyretic, and antitussive; Bupleurum and its active ingredient saikosaponin have anti-inflammatory effects, and its anti-inflammatory effects are related to promoting adrenal cortical system Function, etc.; saikosaponin has the effect of lowering plasma cholesterol; Bupleurum has good anti-fatty liver, anti-hepatic damage, choleretic, lowering transaminase, stimulating intestinal smooth muscle, inhibiting gastric acid secretion, anti-ulcer, inhibiting trypsin, etc. Bupleurum decoction has an inhibitory effect on Mycobacterium tuberculosis; in addition, Bupleurum also has anti-cold virus, increased protein biosynthesis, anti-tumor, anti-radiation and enhanced immune function.

Banlangen, the pharmacological effect of this product is that this product has inhibitory effects on a variety of Gram-positive bacteria, Gram-negative bacteria, influenza viruses, arboviruses, and parotid viruses; it can enhance immune function; it has obvious antipyretic effects; this product The indirubin contained in it has significant anti-leukemia effect; Radix isatidis polysaccharide can reduce the content of serum cholesterol and triglyceride in experimental animals, and reduce the content of MDA, thus proving that the crystal has anti-oxidation effect.

Smilax smilax, the pharmacological effect is that astilbin contained in this product has obvious diuretic and analgesic effects; it is effective against Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, Pseudomonas aeruginosa, typhoid bacillus, Shigella flexneri, diphtheria bacillus and Bacillus anthracis have inhibitory effect; it has a certain inhibitory effect on rat liver cancer and transplanted tumors; it is inferred from animal experiments that this product can selectively inhibit cellular immune response by affecting the inflammatory process of T lymphocytes releasing lymphokines; in addition Can still relieve mercury poisoning; obviously antagonize the toxicity of gossypol.

Alisma has a diuretic effect, can increase urine volume, increase the excretion of urea and chloride, and has a more obvious diuretic effect on nephritis patients. It has antihypertensive, hypoglycemic, and anti-fatty liver effects. It has inhibitory effect on Staphylococcus aureus, Streptococcus pneumoniae and Mycobacterium tuberculosis.

Raw barley, coix seed decoction, alcohol and acetone extract have obvious inhibitory effect on cancer cells; coix seed lactone has inhibitory effect on small intestine; its fatty oil can reduce serum calcium and blood sugar, and has antipyretic, sedative, Analgesic effect.

Rehmannia glutinosa, the water extract of this product has antihypertensive, sedative, anti-inflammatory, anti-allergic effects; its liquid extract has cardiotonic and diuretic effects; its ethanol extract has the effect of shortening blood clotting time; Liuwei Dihuang with its main drug Pills have the effects of lowering blood pressure, improving renal function, and anti-tumor; Rehmannia glutinosa can resist the decrease of plasma corticosterone concentration after continuous administration of dexamethasone, and can prevent the atrophy of the adrenal cortex. The role of cell number, and can enhance the phagocytic function of reticuloendothelial cells, especially for those with low immune function.

Purslane, the ethanol extract and water decoction of this product have significant inhibitory effects on Shigella, and also have certain inhibitory effects on Escherichia coli, typhoid bacillus, Staphylococcus aureus, and microsporum duangi. The fresh juice and boiling water extract of this product can increase the tension of the isolated ileum of animals, enhance intestinal peristalsis, and relax the colon and duodenum in a dose-dependent manner; oral or intraperitoneal injection of its water extract can relax skeletal muscles . The extract of this product has obvious effects of anti-oxidation, anti-aging and moisturizing and beautifying; its injection has obvious excitatory effect on uterine smooth muscle; this product can increase blood potassium concentration; it still has a dose-dependent effect on myocardial contractility Two-way adjustment; in addition, there are diuretic and cholesterol-lowering effects.

Scrophulariaceae, the water extract, alcohol extract and decoction of this product all have the effect of lowering blood pressure; the aqueous solution of the alcohol extract can increase the nutritional blood flow of the mouse myocardium, and can resist the coronary artery contraction caused by pituitrin: the Products against Staphylococcus aureus, diphtheria bacillus, typhoid bacillus, beta-hemolytic streptococcus, Pseudomonas aeruginosa, Shigella flexneri, Escherichia coli, Trichophyton mentagrophytes, Epidermophyton flocculus, Microbacillus lanoides and Asteroides Nocardia have inhibitory effect. In addition, this product also has anti-inflammatory and sedative properties. Anticonvulsant effect.

Licorice, licorice has anti-arrhythmic effects: it has anti-ulcer, inhibits gastric acid secretion, relieves gastrointestinal smooth muscle spasm and analgesic effect, and has synergistic effect with paeoniflorin, the active ingredient of peony; it can promote the secretion of pancreatic juice; it has obvious antitussive effect , the expectorant effect is also more significant, and there is a certain asthma effect; it has antibacterial, antiviral, anti-inflammatory, anti-allergic effects; it can protect the inflamed throat and tracheal mucosa; it has a detoxification effect similar to glucuronic acid for certain poisons; It has the effect similar to adrenal cortex hormone; it also has anti-diuretic, lipid-lowering, and liver-protecting effects.

The present invention follows the principle of "monarch, minister, assistant, and envoy" in traditional Chinese medicine to send prescriptions and medicines, conforms to the characteristic treatment of traditional Chinese medicine based on syndrome differentiation and treatment, and is also supported by modern pharmacological research.

The Chinese herbal medicine of the present invention has the effects of cooling blood and detoxifying, promoting dampness and turbidity, and nourishing yin and promoting body fluid, and is suitable for the treatment of genital herpes, and has precise compatibility, quick effect, high cure rate, low recurrence rate, simple preparation, low cost, and at the same time, Because the medicinal materials of each component are pure natural plants, the prescription does not have any toxic and side effects and is safe to take.

Detailed ways

The Chinese herbal medicine for treating genital herpes of the present invention is obtained by the inventor's accumulated teaching and research and clinical experience of miscellaneous diseases for more than ten years, as well as the theoretical research of traditional Chinese and Western medicine, so that the clinical symptoms and signs will disappear quickly. Dampness, the effect of invigorating the spleen and stomach, is used clinically, and effect is obvious, and experiment proves, and the weight ratio of its each component of the present invention all has curative effect preferably in the following range: Gentiana 10-15 part, Scutellaria baicalensis 10-15 parts, Bupleurum 10-15 parts, Banlangen 15-30 parts, Smilax 15-20 parts, Plantago 10-15 parts, Alisma 10-15 parts, raw barley 15-30 parts, raw land 15- 20 parts, purslane 15-20 parts, Scrophulariaceae 10-15 parts, licorice 6-10 parts.

Above all medicines are pulverized into fine flour altogether and adopt conventional method to be made into pill by pill machine, 10g a bag, 3 times a day, 1 bag, oral administration once, 15 days a course of treatment.

Main functions: cool blood and detoxify, remove dampness and turbidity, nourish yin and promote body fluid.

Treatment range: primary genital herpes and recurrent genital herpes caused by herpes simplex virus.

During the period of taking the medicine, fast spicy, fat and cold food. It is contraindicated for patients with deficiency-heat symptoms caused by spleen-stomach deficiency and yin deficiency and yang hyperactivity.

Clinical Trials

1. General information

From March 2009 to March 2013, a total of 138 patients with genital herpes were treated. Age ranged from 21 to 53 years old, 85 males and 53 females.

2. Diagnostic criteria

1. Past history: history of extramarital sexual contact or spouse infection history and other close contact history.

2. Clinical manifestations:

2.1 Primary genital herpes: The incubation period is 2-7 days. Scattered or grouped erythema and papules develop into blisters on the genitals or around the anus. After 3-5 days of ulceration, they become erosions, ulcers or scabs, accompanied by pain. Systemic symptoms are accompanied by systemic symptoms such as fever, fatigue, and swollen and tender inguinal lymph nodes. The course of the disease lasts 2-3 weeks.

2.2 Recurrent genital herpes: It usually recurs within one year after primary genital herpes, often due to cold, fatigue and other incentives. The clinical symptoms are mostly the same as those of primary genital herpes, and the skin lesions can heal within 7-10 days.

3. Experimental inspection:

3.1 Cytological examination (tzanck smear): multinucleated giant cells or intranuclear viral inclusions can be seen under the microscope.

3.2 Virus culture: Herpes simplex virus and cytopathic.

3. Treatment plan

With reference to the specific embodiment, 1-3 courses of treatment are used in succession.

4. Curative effect evaluation standard

Cure: the clinical symptoms disappeared, the skin lesions subsided, and there was no recurrence within one year.

Significantly effective: clinical symptoms disappear, skin lesions subside, recurrence <2 times within one year.

Effective: clinical symptoms disappear, skin lesions subside, relapse ≥ 2 times within one year.

Ineffective: clinical symptoms and skin lesions have no obvious changes or aggravation from before treatment.

5. Statistics

Among the 138 patients, 96 were cured, 21 were markedly effective, 14 were effective, and 7 were ineffective. The total effective rate was 94.92%.

Typical cases

Case 1: Mr. Sun, 25 years old, from Fangcheng, Henan, reported that he had unclean sex life 6 days ago, and found 7 or 8 red papules with itching on the glans and foreskin 3 days ago, and then developed It is a small blister, and after ulceration, the surface is eroded and has a burning sensation, accompanied by systemic symptoms such as low-grade fever, fatigue, frequent urination, urgency, and urethral tingling. Experimental examination: Cytological examination (tzanck smear) showed nuclear viral inclusions under the microscope. The admission diagnosis was primary genital herpes. After taking the medicine of the present invention for 1 course of treatment, more than 60% of the skin lesions disappeared, and other clinical symptoms were also obviously taken a turn for the better. Then continue to take our medicine for 1 course of treatment, the skin lesions all disappear, and other clinical symptoms also disappear completely, and there is no recurrence after half a year of telephone follow-up.

Case 2: Ms. Zeng, 31 years old, from Tongbai, Henan, reported that she had dirty sex many times. One week ago, I felt a burning sensation at the vaginal opening, surrounded by groups of small blisters. Three days later, ulceration and erosion aggravated the pain, persistent low-grade fever, headache, and physical examination findings: swollen and tender inguinal lymph nodes, and cytological examination in the laboratory examination (tzanck smear): Intranuclear viral inclusions were seen under the microscope, and the diagnosis was primary genital herpes. Take 1 course of treatment of the medicine of the present invention, the damaged and eroded part heals, and other clinical symptoms disappear, and there is no recurrence after telephone follow-up after 1 year.

Case 3: Mr. Jiang, 46 years old, from Nanyang City, Henan Province, suffered from genital herpes because of a history of unclean sex 3 years ago. During the period of illness, Western medicine such as acyclovir was used for treatment, but the effect was not satisfactory, and the disease occurred 2-3 times a year, which seriously affected normal work and married life. Because the cold recurred 2 weeks ago, there were ulcers on the glans, penis, and scrotum during this visit, accompanied by swelling, itching and pain. Experimental inspection: there is herpes simplex virus lesion in virus culture, is diagnosed as recurrent genital herpes, takes 2 courses of treatment of medicine of the present invention continuously, and ulcer surface heals, and accompanying symptom disappears. There was no recurrence in the telephone follow-up after 1 year.

Case 4: Mr. Li, a 29-year-old man from Dengzhou, Henan, had recurrent herpes balans for more than 2 years. After 1 week of unclean sex life, scattered red dots appeared on the glans, and then developed into papules, erosion and exudation, painful urination, HSV-2 virus was found in blood test, and genital herpes was diagnosed for more than 2 years. Western medicine antiviral treatment was used for the initial attack, the curative effect was average, and the disease gradually worsened, with 3 attacks per year to 1 relapse every 2 months, accompanied by itching and pain in the penis. Take 2 courses of treatment of medicine of the present invention continuously, curative effect is very good, follow up a case by regular visits to by telephone after half a year, do not relapse.

Case 5: Ms. Xia, 41 years old, from Zhumadian, Henan Province, felt burning and itching in the perineum one year ago, and then developed several herpes. Cytological examination (tzanck smear): viral inclusions in the nucleus were seen under the microscope, and she was diagnosed by the hospital. The genital herpes was confirmed by inspection, and it was cured after treatment with ribavirin and other western medicines. Thereafter 1 year, often relapse before menstrual cramps, continue to use western medicine treatment, the effect is not good, and the constitution is weaker and weaker, then I go to a doctor, after taking the medicine of the present invention for 2 courses of treatment, no recurrence is found in telephone follow-up after 1 year, constitution Also gradually improved.

Case 6: Mr. Yang, 38 years old, from Yexian County, Henan Province, found 4 scattered blisters in the coronal groove of the glans penis 5 days ago, flushing around with burning sensation, and he reported that he could not stop urinating. After inquiring, he suffered from genital herpes half a year ago, and healed up after taking medicine. The specific medicine is unknown. Experimental examination: there are herpes simplex virus lesions in virus culture. Checked and diagnosed as recurrent genital herpes by our hospital, after taking 1 course of treatment of medicine of the present invention, symptom disappears, telephone follow-up visits after half a year, also does not see recurrence.

Case 7: Ms. Huang, 28 years old, from Zhengzhou, Henan Province, told herself that her husband infected her with genital herpes one year ago, so she was treated in a local hospital in Zhengzhou. Herpes simplex virus lesions were found in the virus culture, and Valacyclovir hydrochloride was taken orally. The effect of antiviral drugs is general, and he was introduced to our office for treatment. The physical examination found: there were scattered blisters and 2 ulcers around the vaginal opening and anus, accompanied by low-grade fever, fatigue, increased leucorrhea odor, pain at the urethral opening, swollen lymph nodes on both sides of the groin, yellow greasy tongue coating, and rapid pulse. After taking 2 courses of treatment of medicine of the present invention, symptom disappears, and for solid curative effect, the patient continues with a course of treatment. After 1 year, a telephone follow-up visit showed no recurrence.

Case 8: Mr. Zhang, 53 years old, from Fangcheng, Henan Province, had herpes in the mouth half a month ago and had not been treated. Herpes also appeared in the penis one week ago, accompanied by tingling pain in the urethra and burning sensation at the opening of the urethra. Cytological examination (tzanck Smear): Virus inclusion bodies in the nucleus were seen under the microscope, and it was diagnosed as genital herpes. The patient did not eat well due to oral herpes pain, with dull complexion, yellow and greasy tongue coating, and slippery pulse. Take 1 course of treatment of medicine of the present invention and exhort the patient to rinse mouth after meal every day, herpes all subsides, and clinical symptom disappears completely. There was no recurrence in the telephone follow-up after 1 year.

Case 9: Ms. Li, 49 years old, from Zhenping County, Nanyang, said that half a month ago, she had red, swollen, hot pain at the mouth of the urethra, followed by scattered small blisters, increased leucorrhea, yellow color and peculiar smell, and burning, astringent pain when urinating, so she came to me hospital treatment. Physical examination found that the right inguinal lymph node was enlarged, the fur was yellow and greasy, and the pulse was stringy and rapid. Cytological examination (tzanck smear): Under the microscope, intranuclear viral inclusion bodies were seen, and the diagnosis was genital herpes. Because the patient believed that the curative effect of traditional Chinese medicine was slow, he was first given western medicine treatment, and after taking oral antiviral drugs such as acyclovir for 2 weeks, the effect was not good, so he was persuaded to take traditional Chinese medicine for treatment. After taking 1 course of treatment of medicine of the present invention, clinical symptom disappears completely. There was no recurrence in the telephone follow-up after 1 year.

Case 10: Mr. Sun, 47 years old, from Zhoukou, Henan Province, suffered from psoriasis for 3 years, the disease recurred, and he was always weak. One year ago, she was admitted to the hospital for herpes simplex virus lesions in the virus culture. She suffered from genital herpes. She first self-administered acyclovir and other drugs, which did not work well, and then took antiviral and other targeted infusion treatments at the local hospital, but still did not see improvement. The patient suffered from illnesses for a long time and became emaciated. After Western medicine treatment, he experienced side effects such as dizziness, nausea, and loss of appetite. He was admitted to our hospital for treatment. The physical examination found that the patient's penis had scattered blisters, the surrounding skin was flushed, accompanied by burning, itching pain, swollen inguinal lymph nodes on both sides, low-grade fever, fatigue, yellow greasy fur, and weak pulse. After taking the medicine of the present invention for 2 courses of treatment, the clinical symptoms took a turn for the better, and the vesicles of the penis subsided substantially, and the inguinal lymph nodes were not enlarged. For solid curative effect, continue to take the medicine of the present invention for 1 course of treatment, and the skin lesion was healed, and the clinical symptoms disappeared completely. Telephone follow-up 1 year later showed no recurrence.

Claims (1)

1. A Chinese herbal medicine for the treatment of genital herpes, characterized in that: it is prepared from the raw materials of the following parts by weight: 10-15 parts of Gentiana, 10-15 parts of Scutellaria baicalensis, 10-15 parts of Bupleurum, 15-30 parts of Radix Radix 15-20 parts of smilax, 10-15 parts of plantago, 10-15 parts of Alisma, 15-30 parts of raw barley, 15-20 parts of raw land, 15-20 parts of purslane, 10-15 parts of Scrophulariaceae 6-10 parts of licorice.