CN102018807A - Medicine composition for treating gynaecologic trichomonas vaginitis and preparation method thereof - Google Patents
Medicine composition for treating gynaecologic trichomonas vaginitis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine composition for treating gynaecologic trichomonas vaginitis and a preparation method thereof, which belongs to the technical field of medicine. The medicine composition comprises raw materials such as golden thread, lightyellow sophora root, common cnidium fruit, pricklyash peel, alum, Chinese gentian and borneal, has functions of clearing heat, removing toxin, drying dampness and killing worms, and is used for treating trichomonas vaginitis. The curative effect is obvious through many years of clinical application.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis, have heat-clearing and toxic substances removing, the effect of removing dampness and killing parasites; The clinical trichomonal vaginitis that is used for.The invention still further relates to this preparation of drug combination method, belong to medical technical field.
Background technology
Trichomonal vaginitis (trichomonal vaginitis) is the common disease of gynecological.It is per vaginam trichomonal.Trichomonal vaginitis can directly infect by sexual intercourse, also can pass through common plunge bath, swimming pool, infect indirectlies such as sitting type toilet seat.Trichomonal vaginitis not only can influence women's daily life, consequence such as also might lead to complications, infertile, and serious also might bring out precancerous lesion.Therefore, in time treat trichomonal vaginitis.
Trichomonal vaginitis belongs to the traditional Chinese medical science " leukorrhagia " and reaches " pudendal pruritus " category.Chinese medicine think its cause of disease mainly be in damp-heat accumulation, worm-eaten the moon due to, pathogenesis is for the liver,spleen,kidney malfunction and appoint that to be with two arteries and veins to lose solid.Damp and hot heresy has inside and outside branch.Cause damp and invade outward as occupying wetland etc. for a long time, strongly fragrant and heat-transformation, or menstrual period, puerperal, damp and hot evil poison is taken advantage of a weak point in opponent's defence and the people, and this is that diseases caused by exogenous pathogenic factor are damp and hot.If plain body deficiency-weakness of spleen-QI, or depression of liver-QI, wood gram spleen soil, dysfunction of the spleen in transportation stays in water is wet, stops pouring down Jiao, accumulate and heat-transformation, then be that interior life is damp and hot.Damp-heat accumulation, ligament are not solid, and then leukorrhagia increases, yellow skin.With the passing of time the damp contamination becomes poison, or infects the pyretic toxicity pathogen, the absurd row of intenseness of heat forcing blood, or noxious dampness corrosion skin, and then visible leukorrhagia pus and blood, or see " erosion of the vulva " " erosion of vulva ".Web rot is infested, or health preserving is careless, the evil straight external genitals of violating of worm, causalgia in pudendal pruritus, the moon then in worm-eaten the moon.Primary disease is trouble with the damp, so its disease is touching, outbreak repeatedly is difficult for speed more, Chang Bingfa menoxenia, amenorrhea, illness such as infertile.Rule together inside and outside taking in the treatment, the men and women rules together, the method effect of continuous use is fine.The direct result of prolonged application metronidazole makes pathogenic bacteria produce drug resistance exactly, destroy the restricting relation between vaginal microbial flora, intravaginal flora is got muddled, mutual inhibitory action is changed, cause conk vigorous, treatment cycle constantly prolongs, and the touching difficulty of inflammation is more brought unnecessary spirit and economic loss to the patient.
Fructus Cnidii temperature in the medicine of the present invention, kidney and enhancing body, killing parasites for relieving itching has the effect of the trichomonas vaginitis killed.The Radix Sophorae Flavescentis heat clearing and damp drying, wind dispelling insecticide, diuresis, Rhizoma Coptidis, Radix Gentianae can be strengthened the effect of heat-clearing and toxic substances removing parasite killing, Pericarpium Zanthoxyli parasite killing dispelling wind for relieving itching, the Borneolum Syntheticum heat-clearing and toxic substances removing is antipruritic.All medicines share, and leukorrhagia is controlled in the parasite killing dehumidifying, heat-clearing and toxic substances removing, and the only pudendal pruritus of dispeling the wind has good therapeutical effect to trichomonal vaginitis.
Prior art by retrieval, finding has with the similar prior art of patent of the present invention: Dong Li the present invention a kind of external used medicine for the treatment of various gynecological diseases---Fuyanyu.No. 1 powder and capsule cures mainly multiple gynaecopathia such as vulvitis, vaginitis, cervical erosion, cervicitis.Comprise Chinese medicine: Rhizoma Pinelliae, float the Rhizoma Pinelliae, Herba Andrographis, Radix Sophorae Tonkinensis, Radix Arnebiae (Radix Lithospermi), Herba Senecionis Scandentis, Rhizoma Polygoni Cuspidati, Herba Solani Nigri, Fructus Cnidii, dried Alumen, Borneolum Syntheticum.No. 2 capsule for suppository cures mainly the early metaphase cervical cancer, comprises Chinese medicine: Herba Crotalariae sessiliflorae, rhizoma sparganic, Rhizoma Curcumae, Pseudobulbus cremastrae seu pleiones, process arsenic, Realgar, Fructus Cnidii, Borax, Moschus, dried Alumen, Borneolum Syntheticum, Endothelium Corneum Gigeriae Galli.(application (patent) number: CN97112812.X).But compare with medicine of the present invention, drug prescription taste of Chinese medicine of the present invention is few, and is conventional medicine, low price; Preparation technology is simple, and production cost is low, has alleviated patient economy burden.
The medicine of treatment trichomonal vaginitis is many based on the chemical medicine composition on the existing market, though therapeutic effect is preferable, is easy to generate untoward reaction such as drug dependence and heavy damage vagina internal medium even the vagina inner skin of burning; Medicine of the present invention is a pure Chinese medicinal preparation, have no adverse reaction, clinical practice for many years, effect is obvious.
Summary of the invention
Pharmaceutical composition of the present invention is to be prepared from by Chinese medicines such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxylies, and is theoretical for instructing treatment trichomonal vaginitis with the traditional Chinese medical science " heat-clearing and toxic substances removing, removing dampness and killing parasites ".
Purpose of the present invention just provides a kind of pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis, and this pharmaceutical composition has heat-clearing and toxic substances removing, the effect of removing dampness and killing parasites, clinical practice treatment trichomonal vaginitis.
Another object of the present invention provides this preparation of drug combination method.
For achieving the above object, pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis provided by the invention is formed by the following raw medicaments in portion by weight processing and preparing:
Rhizoma Coptidis 10-30 part Radix Sophorae Flavescentis 10-20 part Fructus Cnidii 10-20 part Radix Gentianae 5-15 part
Pericarpium Zanthoxyli 5-10 part Alumen 5-10 part Borneolum Syntheticum 0.2-0.8 part.
Preferred version is formed by the following raw medicaments in portion by weight processing and preparing:
Rhizoma Coptidis 15-25 part Radix Sophorae Flavescentis 12-18 part Fructus Cnidii 12-18 part Radix Gentianae 8-12 part
Pericarpium Zanthoxyli 6-9 part Alumen 6-8 part Borneolum Syntheticum 0.3-0.6 part.
Preferred plan is formed by the following raw medicaments in portion by weight processing and preparing:
10 parts of 15 parts of Radix Gentianae of 15 parts of Fructus Cnidiis of 20 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.5 part of 7.5 parts of Borneolum Syntheticum of 8 parts of Alumen of Pericarpium Zanthoxyli.
The present invention treats the pharmaceutical composition of gynecological's trichomonal vaginitis, and preparation is an external preparation, comprises any existing clinical suitable dosage form such as washing liquid, suppository, capsule.
Described weight portion can be weight metering units such as gram, two, jin, kilogram, ton.
Pharmaceutical composition of the present invention can adopt respectively the distinguish the flavor of medical material of conventional method in will writing out a prescription to carry out compatibility in proportion, makes various clinical suitable dosage forms by existing preparation process, and the used medical material of respectively distinguishing the flavor of is the Chinese crude drug that commercially available process is up to the standards.
The preparation method that the present invention relates to is as follows:
(1) it is standby to get above-mentioned qualified Chinese crude drug;
(2) Alumen, Borneolum Syntheticum powder are broken into fine powder, cross 100 mesh sieves;
(3) five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli decoct 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor;
(4) get final product in the powder adding (3) that step (2) is obtained.
The preparation of washing liquid: (4) medicinal liquid is stirred evenly, add an amount of distilled water to ormal weight and get final product.
The suppository preparation: get above-mentioned (4) medicinal liquid and stir evenly, be condensed into dry extract, sterilization is 30 minutes under ultra-violet lamp, every 100g powder adds Polyethylene Glycol-4000280g as substrate, puts heat fused in the water-bath, stirs, impouring scribbles in the mould of liquid Paraffin, and every heavy 1.2g promptly gets suppository.
The capsule preparation: get above-mentioned (4) medicinal liquid and stir evenly, be condensed into dry extract, be ground into fine powder, sterilization is 30 minutes under ultra-violet lamp, the capsule for vagina of packing into, and every dress 0.4g promptly gets capsule.
The pharmaceutical composition of the present invention medical material modern pharmacological research of respectively distinguishing the flavor of shows:
1. Rhizoma Coptidis: hardship, cold.GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel.Heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, vomiting, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed, the conjunctival congestion acid regurgitation, the carbuncle furuncle is quenched one's thirst in toothache; External treatment eczema, eczema, auditory meatus is suppurated.
Rhizoma Coptidis main component berberine hydrochloride has anti-trichomonal, anti-leishmania donovani, anti-trypanosomicide, kill effect such as paramecium.
2. Radix Sophorae Flavescentis: hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Heat clearing and damp drying, parasite killing, diuresis.Be used for hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
The matrine that Radix Sophorae Flavescentis contains has active anticancer, oxymatrine has effect in increasing leukocyte, oxymatrine can obviously resist the exudative inflammation that Oleum Tiglii, carrageenin (rat) and glacial acetic acid (mice) bring out, all there is antibacterial action the matrine inside and outside, action intensity is suitable with chloromycetin in the body, the alcohol leaching mastic has the anti-trichomonal effect outward, and its intensity and hops are close.
3. Fructus Cnidii: hot, bitter, temperature; Slightly poisonous.Return kidney channel.Warming the kidney to invigorate YANG, dampness is dispeled the wind, parasite killing.Be used for sexual impotence, the official is cold, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, external treatment vulval eczema, married woman's pudendal pruritus; Trichomonal vaginitis.
The xanthotoxol that Fructus Cnidii contains has significant antifungal effect, and Fructus Cnidii also has anti-trichomonal effect, gonadotropic Effect, local anesthetic action, and osthole can suppress the mice passive cutaneous anaphylaxis, PCA strongly.
4. Radix Gentianae: hardship, cold.Return liver, gallbladder meridian.Heat clearing and damp drying, eliminating pathogen in the liver gallbladder fire.Be used for jaundice due to damp-heat, swelling of the vulva pudendal pruritus, leukorrhagia, persistent erection of the penis, eczema pruritus, conjunctival congestion, deafness, hypochondriac pain, bitter taste, convulsion with spasms.
5. Pericarpium Zanthoxyli: suffering, temperature.Return spleen, stomach, kidney channel.Warming middle-JIAO to relieve pain, killing parasites for relieving itching.Be used for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation, ascariasis; External treatment eczema pruritus.Pericarpium Zanthoxyli is to 10 kinds of gram positive bacterias such as anthrax bacillus, Hemolytic streptococcus, diphtheria corynebacterium, Diplococcus pneumoniae, staphylococcus aureus, lemon yellow and Staphylococcus albus, bacillus subtilis, and enteral pathogenic bacterium such as escherichia coli, Song Nei Shi dysentery bar flute, Bacillus proteus, typhoid fever and Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera all have the obvious suppression effect.
6. Alumen: external detoxifcation parasite killing, dampness removing to stop itchin; Have effects such as antibiotic, anti-trichomonas vaginitis.
7. Borneolum Syntheticum has antiinflammatory action, analgesic effect, antibacterial action: Borneolum Syntheticum can suppress or kill clinical common bacterias such as staphylococcus aureus, beta hemolytic streptococcus, viridans streptococci.
For showing therapeutic effect of the present invention, with 20 parts of Rhizoma Coptidis, 15 parts of Radix Sophorae Flavescentiss, 15 parts of Fructus Cnidiis, 10 parts of Radix Gentianae, 8 parts in Pericarpium Zanthoxyli, 7.5 parts in Alumen, 0.5 part of Borneolum Syntheticum; Adopt Alumen, Borneolum Syntheticum powder to be broken into fine powder, cross 100 mesh sieves; Five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli decoct 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned powder, stir evenly, add an amount of distilled water and make washing liquid.Wash pudendum and washing vagina, matched group was with 1: 5000 potassium permanganate liquid washing vagina.10 times is a course of treatment.
Effect assessment: recovery from illness: dense property or foam sample leucorrhea disappearance pruritus vulvae, frequent micturition dysurea disappear, and no vulvovaginal hyperemia is after the treatment, in the clean back check of each menstruation secretions, through 3 feminine genders of continuous review.Produce effects: leucorrhea reduces, and pruritus vulvae, frequent micturition dysurea symptom take a turn for the better, and pudendum does not have hyperemia, and secretions smear for microscopic examination infusorian reduces debility.Invalid: clinical symptoms and sign do not have change, and the infusorian number does not have change.Recovery from illness adds up to effectively with produce effects.
Drug therapy 98 routine trichomonal vaginitis of the present invention, total effective rate reaches 98.0%.
The specific embodiment
Below with embodiment the pharmaceutical composition of treatment of the present invention gynecological trichomonal vaginitis is further described; this will help the present invention and effect thereof are further understood; embodiment does not limit protection scope of the present invention, and its protection domain is decided by claim.
Embodiment 1
5 parts of 10 parts of Radix Gentianae of 10 parts of Fructus Cnidiis of 10 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.2 part of 5 parts of Borneolum Syntheticum of 5 parts of Alumen of Pericarpium Zanthoxyli
Get Alumen, Borneolum Syntheticum powder is broken into fine powder, crosses 100 mesh sieves; Other gets five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli and decocts 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned fine powder, stir evenly, add an amount of distilled water to ormal weight and get final product.
Embodiment 2
8 parts of 12 parts of Radix Gentianae of 12 parts of Fructus Cnidiis of 15 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.3 part of 6 parts of Borneolum Syntheticum of 6 parts of Alumen of Pericarpium Zanthoxyli
Get Alumen, Borneolum Syntheticum powder is broken into fine powder, crosses 100 mesh sieves; Other gets five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli and decocts 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned fine powder, stir evenly, be condensed into dry extract, be ground into fine powder, sterilization is 30 minutes under ultra-violet lamp, the capsule for vagina of packing into, and every dress 0.4g promptly gets capsule.
Embodiment 3
15 parts of 20 parts of Radix Gentianae of 20 parts of Fructus Cnidiis of 30 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.8 part of 10 parts of Borneolum Syntheticum of 10 parts of Alumen of Pericarpium Zanthoxyli
Get Alumen, Borneolum Syntheticum powder is broken into fine powder, crosses 100 mesh sieves; Other gets five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli and decocts 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned fine powder, stir evenly, be condensed into dry extract, sterilization is 30 minutes under ultra-violet lamp, every 100g powder adds Polyethylene Glycol-4000 280g as substrate, puts heat fused in the water-bath, stirs, impouring scribbles in the mould of liquid Paraffin, and every heavy 1.2g promptly gets suppository.
Embodiment 4
12 parts of 18 parts of Radix Gentianae of 18 parts of Fructus Cnidiis of 25 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.6 part of 8 parts of Borneolum Syntheticum of 9 parts of Alumen of Pericarpium Zanthoxyli
Get Alumen, Borneolum Syntheticum powder is broken into fine powder, crosses 100 mesh sieves; Other gets five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli and decocts 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned fine powder, stir evenly, be condensed into dry extract, sterilization is 30 minutes under ultra-violet lamp, every 100g powder adds Polyethylene Glycol-4000 280g as substrate, puts heat fused in the water-bath, stirs, impouring scribbles in the mould of liquid Paraffin, and every heavy 1.2g promptly gets suppository.
Embodiment 5
10 parts of 15 parts of Radix Gentianae of 15 parts of Fructus Cnidiis of 20 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.5 part of 7.5 parts of Borneolum Syntheticum of 8 parts of Alumen of Pericarpium Zanthoxyli.
Get Alumen, Borneolum Syntheticum powder is broken into fine powder, crosses 100 mesh sieves; Other gets five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli and decocts 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor; Add above-mentioned fine powder, stir evenly, add an amount of distilled water to ormal weight and can obtain washing liquid.
Claims (5)
1. pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis is characterized in that being formed by the following raw medicaments in portion by weight processing and preparing:
Rhizoma Coptidis 10-30 part Radix Sophorae Flavescentis 10-20 part Fructus Cnidii 10-20 part Radix Gentianae 5-15 part
Pericarpium Zanthoxyli 5-10 part Alumen 5-10 part Borneolum Syntheticum 0.2-0.8 part.
2. a kind of pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis according to claim 1 is characterized in that being formed by the following raw medicaments in portion by weight processing and preparing:
Rhizoma Coptidis 15-25 part Radix Sophorae Flavescentis 12-18 part Fructus Cnidii 12-18 part Radix Gentianae 8-12 part
Pericarpium Zanthoxyli 6-9 part Alumen 6-8 part Borneolum Syntheticum 0.3-0.6 part.
3. a kind of pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis according to claim 1 is characterized in that being formed by the following raw medicaments in portion by weight processing and preparing:
10 parts of 15 parts of Radix Gentianae of 15 parts of Fructus Cnidiis of 20 parts of Radix Sophorae Flavescentiss of Rhizoma Coptidis
0.5 part of 7.5 parts of Borneolum Syntheticum of 8 parts of Alumen of Pericarpium Zanthoxyli.
4. according to claim 1 or 2 or 3 one of them described a kind of pharmaceutical composition for the treatment of gynecological's trichomonal vaginitis, it is characterized in that preparation is an external preparation, comprise washing liquid, suppository, capsule etc.
5. according to the described a kind of preparation method for the treatment of gynecological's trichomonal vaginitis of claim 1 to 3, it is characterized in that comprising the steps:
(1) it is standby to get above-mentioned qualified Chinese crude drug;
(2) Alumen, Borneolum Syntheticum powder are broken into fine powder, cross 100 mesh sieves;
(3) five tastes medical materials such as Rhizoma Coptidis, Radix Sophorae Flavescentis, Fructus Cnidii, Radix Gentianae, Pericarpium Zanthoxyli decoct 3 times, each 1.5 hours, collecting decoction, filter, filtrate is condensed into the relative density of measuring in the time of 60 ℃ be 1.05~1.10 clear paste, adds equivalent 75% ethanol, stir evenly, left standstill 24 hours, and filtered, filtrate recycling ethanol is to there not being the ethanol flavor;
(4) get final product in the powder adding (3) that step (2) is obtained.
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101810721A (en) * | 2010-04-09 | 2010-08-25 | 重庆希尔安药业有限公司 | Medicinal composition for treating various gynecological diseases and preparation method thereof |
CN102743626A (en) * | 2012-06-17 | 2012-10-24 | 伊金萍 | Preparation method of Chinese medicine irrigation solution for treating vomit type trichomonas vaginitis |
CN103610776A (en) * | 2013-12-04 | 2014-03-05 | 林军 | Soup for nursing and cleaning gynaecological vulvae |
CN103655868A (en) * | 2012-09-11 | 2014-03-26 | 张献奎 | Prescription for treating navel pruritus |
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2010
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Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101810721A (en) * | 2010-04-09 | 2010-08-25 | 重庆希尔安药业有限公司 | Medicinal composition for treating various gynecological diseases and preparation method thereof |
CN101810721B (en) * | 2010-04-09 | 2015-07-08 | 重庆希尔安药业有限公司 | Medicinal composition for treating various gynecological diseases and preparation method thereof |
CN102743626A (en) * | 2012-06-17 | 2012-10-24 | 伊金萍 | Preparation method of Chinese medicine irrigation solution for treating vomit type trichomonas vaginitis |
CN102743626B (en) * | 2012-06-17 | 2013-09-04 | 伊金萍 | Preparation method of Chinese medicine irrigation solution for treating vomit type trichomonas vaginitis |
CN103655868A (en) * | 2012-09-11 | 2014-03-26 | 张献奎 | Prescription for treating navel pruritus |
CN103610776A (en) * | 2013-12-04 | 2014-03-05 | 林军 | Soup for nursing and cleaning gynaecological vulvae |
CN103610776B (en) * | 2013-12-04 | 2015-08-19 | 王兆霞 | A kind of gynecological pudendum nursing cleaning medicinal liquid |
CN104940767A (en) * | 2015-07-14 | 2015-09-30 | 张军 | Traditional Chinese medicine composition resistant to pathogenic microorganisms and preparation method and application of traditional Chinese medicine composition |
CN104940767B (en) * | 2015-07-14 | 2018-11-02 | 张军 | Chinese medicine composition of resisting pathogenic microbes and its preparation method and application |
CN105106763A (en) * | 2015-10-08 | 2015-12-02 | 淄博齐鼎立专利信息咨询有限公司 | Traditional Chinese medicine suppository for treating trichomonas vaginitis |
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