CN102887931A - 一种醋酸乌利司他的结晶体及其制备方法 - Google Patents
一种醋酸乌利司他的结晶体及其制备方法 Download PDFInfo
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- CN102887931A CN102887931A CN2012102334667A CN201210233466A CN102887931A CN 102887931 A CN102887931 A CN 102887931A CN 2012102334667 A CN2012102334667 A CN 2012102334667A CN 201210233466 A CN201210233466 A CN 201210233466A CN 102887931 A CN102887931 A CN 102887931A
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样品 | 表观溶解度(mg/ml) |
结晶物(晶型C) | 0.000200 |
结晶物(晶型D) | 0.000290 |
Claims (11)
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CN102887931A true CN102887931A (zh) | 2013-01-23 |
CN102887931B CN102887931B (zh) | 2015-04-15 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014050107A1 (en) * | 2012-09-28 | 2014-04-03 | Aska Pharmaceutical Co., Ltd. | Crystalline polymorphic form of ulipristal acetate |
US9643993B2 (en) | 2012-09-28 | 2017-05-09 | Aska Pharmaceutical Co., Ltd. | Crystalline polymorphic form of ulipristal acetate |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1753905A (zh) * | 2003-01-22 | 2006-03-29 | 克利斯托制药股份有限公司 | 获得17α-乙酰氧基-11β-(4-N,N-二甲氨基苯基)-19-去甲孕甾-4,9-二烯-3,20-二酮的方法 |
CN102241722A (zh) * | 2010-05-12 | 2011-11-16 | 杭州容立医药科技有限公司 | 一种合成孕酮受体调节剂优力司特的纯化方法 |
CN102295674A (zh) * | 2011-07-14 | 2011-12-28 | 四川大学 | 获得高纯度17α-乙酰氧基-11β-(4-N,N-二甲氨基苯基)-19-去甲孕甾-4,9-二烯-3,20-二酮的方法 |
CN102372760A (zh) * | 2010-08-12 | 2012-03-14 | 杭州容立医药科技有限公司 | 一种合成孕酮受体调节剂优力司特的合成方法 |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1753905A (zh) * | 2003-01-22 | 2006-03-29 | 克利斯托制药股份有限公司 | 获得17α-乙酰氧基-11β-(4-N,N-二甲氨基苯基)-19-去甲孕甾-4,9-二烯-3,20-二酮的方法 |
CN102241722A (zh) * | 2010-05-12 | 2011-11-16 | 杭州容立医药科技有限公司 | 一种合成孕酮受体调节剂优力司特的纯化方法 |
CN102372760A (zh) * | 2010-08-12 | 2012-03-14 | 杭州容立医药科技有限公司 | 一种合成孕酮受体调节剂优力司特的合成方法 |
CN102295674A (zh) * | 2011-07-14 | 2011-12-28 | 四川大学 | 获得高纯度17α-乙酰氧基-11β-(4-N,N-二甲氨基苯基)-19-去甲孕甾-4,9-二烯-3,20-二酮的方法 |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2014050107A1 (en) * | 2012-09-28 | 2014-04-03 | Aska Pharmaceutical Co., Ltd. | Crystalline polymorphic form of ulipristal acetate |
US9643993B2 (en) | 2012-09-28 | 2017-05-09 | Aska Pharmaceutical Co., Ltd. | Crystalline polymorphic form of ulipristal acetate |
US9643994B2 (en) | 2012-09-28 | 2017-05-09 | Aska Pharmaceutical Co., Ltd. | Crystalline polymorphic form of ulipristal acetate |
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CN102887931B (zh) | 2015-04-15 |
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Denomination of invention: Ulipristal acetate crystals and preparation method thereof Effective date of registration: 20160616 Granted publication date: 20150415 Pledgee: Qilu bank Limited by Share Ltd Ji'nan high tech branch Pledgor: Shandong Chengchuang Medical Technology Development Co., Ltd. Registration number: 2016370000036 |
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Date of cancellation: 20170821 Granted publication date: 20150415 Pledgee: Qilu bank Limited by Share Ltd Ji'nan high tech branch Pledgor: Shandong Chengchuang Medical Technology Development Co., Ltd. Registration number: 2016370000036 |
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Effective date of registration: 20181228 Address after: 250101 First, Second and Fourth Floors of Quality Inspection Building No. 2350 Kaixin Road, Jinan High-tech Zone, Shandong Province Patentee after: Shandong Chengchuang Blue Sea Pharmaceutical Technology Co., Ltd. Address before: 250101 No. 2350 Pioneer Road, Jinan High-tech Zone, Shandong Province (Shandong Chengchuang Pharmaceutical Technology Development Co., Ltd.) Patentee before: Shandong Chengchuang Medical Technology Development Co., Ltd. |