CN102886023B - 一种治疗风湿骨痛的药物组合物 - Google Patents
一种治疗风湿骨痛的药物组合物 Download PDFInfo
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Abstract
一种治疗风湿骨痛的药物组合物。涉及中药领域，特别是一种治疗风湿骨痛的药物组合物。由以下重量配比的原料组成：续断10-30克、防已10-20克、威灵仙10-30克、紫菀10-20克、厚朴10-20克、木香10-20克、枳壳10-20克、丹参10-30克、葛根10-30克、延胡索10-20克、郁金10-20克、川芎10-30克、白头翁10-20克、红花10-20克、桃红10-20克、苏木5-15克、台乌10-20克、甘草3-12克、黄板10-20克；本发明能活血化瘀，对风湿骨痛有显著疗效。
Description
技术领域
本发明涉及中药领域，特别是一种治疗风湿骨痛的药。
背景技术
根据《我国风湿四病流行病学抽样调查》，风湿病在中国发病率为14%，特种职业（纺织、钢铁机械、化工、矿山石油、港口、军队）高达23.1%，风湿四病的主要发病人群在40-60岁；目前我国估计有1.82亿人患风湿病，40岁以上患者占到9464万人。风湿病给患者造成生活和工作上的行动不便，而且致残率高，对患者本人的生理、心理造成极大的影响，给社会造成极大的负担。虽然目前临床上有许多跌打损伤、风湿骨痛的中草药剂，但临床效果不理想，且有一定的不适感和副作用。
发明内容
本发明本人根据传统的中医理论，挖掘民间祖传秘方，并加以改进的一种疗效显著，副作用小的治疗风湿骨痛的中药配方。
本发明是这样实现的：一种治疗风湿骨痛的药物组合物，由以下重量配比的原料组成：续断10-30克、防已10-20克、威灵仙10-30克、紫菀10-20克、厚朴10-20克、木香10-20克、枳壳10-20克、丹参10-30克、葛根10-30克、延胡索10-20克、郁金10-20克、川芎10-30克、白头翁10-20克、红花10-20克、桃仁10-20克、苏木5-15克、台乌10-20克、甘草3-12克、黄柏10-20克；
进一步：还可以由以下重量配比的原料组成：续断20克、防已15克、威灵仙20克、紫菀15克、厚朴15克、木香15克、枳壳15克、丹参20克、葛根20克、延胡索15克、郁金15克、川芎20克、白头翁15克、红花15克、桃仁15克、苏木10克、台乌15克、甘草6克、黄柏15克。
续断，为川续断科多年生草本植物川续断的根，因能“续折接骨”而得名，秋季采挖，除去根头及须根，用微火烘至半干，堆置“发汗”至内部变绿色时，再烘干，《滇南本草》：“补肝，强筋骨，定经络，止经中（筋骨）酸痛，安胎，治妇人白带，生新血，破瘀血，落死胎，止咳嗽咳血，治赤白便浊。
防已，主治：水肿脚气，小便不利，湿疹疮毒，风湿痹痛，高血压症。一般认为，防己利水消肿作用较强，木防己祛风止痛作用较好。
威灵仙，属于药用植物，药材基源来源较多，《开宝本草》、《本草图经》、《救荒本草》等所载的威灵仙，为玄参科植物；《滇南本草》所载的威灵仙，系菊科植物，而当今使用的多为《中华本草》所载毛莨科植物威灵仙、棉团铁线莲等，国内分布较广，其根及茎入药具有风湿、通经络、消骨哽之功效。
紫菀，一种秋季观赏花卉，根可人药，英文名：Michaelmas daisy 别名：山白菜性味归经苦、甘，微温。归肺经。功能：润肺下气，消痰止咳。主治：痰多喘咳，新久咳嗽，劳嗽咳血。药理：1、祛痰镇咳作用 2、抗菌作用 3、抗癌作用。
厚朴：主治：食积气滞；腹胀便秘；湿阻中焦，脘痞吐泻；痰壅气逆；胸满喘咳。出自《神农本草经》。现为国家Ⅱ级重点保护野生植物。
木香，功效：行气止痛；调中导滞。
枳壳：为双子叶植物药芸香科植物酸橙及其栽培变种近的干燥未成熟果实。 功效：理气宽中 行滞消胀。主治：脾胃气滞，脘腹胀满，气滞胸闷。
丹参，又名赤参，紫丹参，红根等。为双子叶植物唇形科，干燥根及根茎。主产于安徽、河南、陕西等地。功效：活血调经，祛瘀止痛，凉血消痈，清心除烦，养血安神。
葛根，又叫甘葛。是多年生藤本豆科植物，葛根特别肥大，含粉率在25~30\%。因含葛粉多而得名粉葛，又因葛根甘甜，又将粉葛称为甘葛。葛根粉性凉味甘辛，有解表退热，生津、透疹、升阳止泻等多种功能，可治外感发热头痛、高血压颈项强痛、口渴、消渴、麻疹不透、热疹、泄泻等多种疾病。一般的粉葛质韧，纤维性强。
延胡索，又名延胡索、玄胡、元胡。多年生草本，高9-20cm，全株无毛。活血，行气，止痛。延胡索是常用止痛药，善治胃脘疼痛。醋制止痛作用增强。 “心（胃）痛欲死，速觅延胡”。
郁金，功能主治：活血止痛，行气解郁，清心凉血，利胆退黄。用于经闭痛经,胸腹胀痛、刺痛，热病神昏，癫痫发狂，黄疸尿赤。
川芎，原名芎藭。一种中药植物，常用于活血行气，祛风止痛，主要栽培于四川、云南、贵州、广西、湖北等地。 川芎辛温香燥，走而不守，既能行散，上行可达巅顶；又入血分，下行可达血海。活血祛瘀作用广泛，适宜瘀血阻滞各种病症；祛风止痛，效用甚佳，可治头风头痛、风湿痹痛等症。 昔人谓川芎为血中之气药，殆言其寓辛散、解郁、通达、止痛等功能。
白头翁，药用价值高，从上述历代本草专著看出多有记述。中医认为，白头翁有清热解毒、凉血、明目、消赘的功效，有诗曰：“苦温味性白头翁，主入心经与肾经，温症发狂为主治，并消积聚瘕和症。瘿瘤瘰疬皆能散，鼻衄金疮亦可平。阴疝痊兮偏肿愈，秃疮膻腥治亦能。腹痛骨病牙痛止，红痢能将毒性清。肠垢搜刮堪竭净，佐之以酒效尤灵。”具有清热解毒，凉血止痢，燥湿杀虫的功效。
红花，又称草红花。性温，味辛，活血通径、散瘀止痛。用于经闭、痛经、恶露不行、症瘕痞块、跌打损伤。古人常有於血在体内时，常加红花一小把。纱布包煮开可用一天两次泡脚，适用各种静脉曲张，末梢神经炎，血液循环不好，腿脚麻木或青紫等淤血症。
苏木主治活血祛瘀，消肿定痛。主妇人血滞经闭，痛经，产后瘀阻心腹痛，产后血晕，痈肿，跌打损伤，破伤风。
桃仁，药理作用：桃仁提取液能明显增加脑血流量，增加犬股动脉的血流量，降低血管阻力，改善血流动力学状况。提取物能改善动物的肝脏表面微循环，并促进胆汁分泌。桃仁可使小鼠的出血及凝血时间明显延长，煎剂对体外血栓有抑制作用，水煎液有纤维促进作用。桃仁中含45%的脂肪油可润滑肠道，利于排便。桃仁能促进初产妇子宫收缩及出血。水煎剂及提取物有镇痛、抗炎、抗菌、抗过敏作用。桃仁中的苦杏仁苷有镇咳平喘及抗肝纤维化的作用。
苏木，是临床常用的中药，能够行血，破瘀，消肿，止痛。临床常用于治妇人血气心腹痛，经闭，产后瘀血胀痛喘急，痢疾，破伤风，痈肿，扑损瘀滞作痛等等。下面响石潭详细说一下苏木的功效与作用。
台乌，是乌药的道地简称，是乌药中的上品。历代本草典籍中记载：“乌药，以产天台者为胜，故称天台乌药或台乌药”。 具顺气、开郁、散寒、止痛功效，能上理脾胃元气，下通少阴肾经。
甘草是一种补益中草药。功能主治清热解毒，祛痰止咳、脘腹等。喜阳光充沛，日照长气温低的干燥气候。甘草多生长在干旱、半干旱的荒漠草原、沙漠边缘和黄土丘陵地带。
黄柏，为芸香科植物黄皮树或黄檗的干燥树皮。前者习称“川黄柏”，后者习称“关黄柏”。可入药，性味苦寒，有清热燥湿，泻火除蒸，解毒疗疮之功效。
有益技术效果
本发明能活血化瘀，对风湿骨痛有显著疗效。
药效评定：共采集风湿病患者样本200例，男115例，女85例。
治愈192例，治愈率打96% 。
具体实施方式：
以下对本发明的具体配方、使用方法及治愈病例进行描述，所举实例只用于解释本发明，并非用于限制本发明的范围。
1、一种治疗风湿骨痛的药物组合物，由以下重量配比的原料组成：续断10克、防已10克、威灵仙10克、紫菀10克、厚朴10克、木香10克、枳壳10克、丹参10克、葛根10克、延胡索10克、郁金10克、川芎10克、白头翁10克、红花10克、桃仁10克、苏木5克、台乌10克、甘草3克、黄柏10克；
制法：开会煮沸30分钟，取汤服用；
用量：每日服4次，每次800ml；
临床病例：赵某某，性别：男，年龄60岁，退休公务员，膝关节酸楚活动受限；遇天气变化（阴天、下雨、刮风）病情加重；有冷风、冷气往身体皮肤钻入感，保暖护膝后舒服；活动后疼痛减轻。曾多次到医院就诊，未见好转，用该处方服用2星期后病情明显好转，1个月后痊愈，至今未见复发。
2、一种治疗风湿骨痛的药物组合物，由以下重量配比的原料组成：续断30克、防已20克、威灵仙30克、紫菀20克、厚朴20克、木香20克、枳壳20克、丹参30克、葛根30克、延胡索20克、郁金20克、川芎30克、白头翁20克、红花20克、桃仁20克、苏木15克、台乌20克、甘草2克、黄柏20克；
制法：开会煮沸30分钟，取汤服用；
用量：每日服4次，每次800ml；
临床病例：王某，性别：男，年龄56岁，肩关节剧痛，活动受限；遇天气变化（阴天、下雨、刮风）病情加重；有冷风、冷气往身体皮肤钻入感，保暖护膝后舒服；活动后疼痛减轻，医院诊断为风湿，用该处方服用2星期后病情明显好转，1个月后痊愈，至今未见复发。
3、一种治疗风湿骨痛的药物组合物，由以下重量配比的原料组成：续断20克、防已15克、威灵仙20克、紫菀15克、厚朴15克、木香15克、枳壳15克、丹参20克、葛根20克、延胡索15克、郁金15克、川芎20克、白头翁15克、红花15克、桃仁15克、苏木10克、台乌15克、甘草6克、黄柏15克。
制法：开会煮沸30分钟，取汤服用；
用量：每日服4次，每次800ml；
临床病例：张某，性别：男，年龄40岁，肩关节麻木，活动受限；遇天气变化（阴天、下雨、刮风）病情加重，医院诊断为风湿，用该处方服用2星期后病情明显好转，1个月后痊愈，至今未见复发。
以上所述仅为本发明的较佳实施例，并不用于限制本发明，在不脱离本发明范围的情况下，还可以对本发明专利进行各种变换及等同代替，因此，本发明专利不局限于所公开的具体实施过程，而应当包括落入本发明专利权利要求范围内的全部实施方案。
Claims (2)
1.一种治疗风湿骨痛的药物组合物，其特征在于，由以下重量配比的原料组成：续断10-30克、防已10-20克、威灵仙10-30克、紫菀10-20克、厚朴10-20克、木香10-20克、枳壳10-20克、丹参10-30克、葛根10-30克、延胡索10-20克、郁金10-20克、川芎10-30克、白头翁10-20克、红花10-20克、桃仁10-20克、苏木5-15克、台乌10-20克、甘草3-12克、黄柏10-20克。
2.根据权利要求1所述的一种治疗风湿骨痛的药物组合物，其特征在于，续断20克、防已15克、威灵仙20克、紫菀15克、厚朴15克、木香15克、枳壳15克、丹参20克、葛根20克、延胡索15克、郁金15克、川芎20克、白头翁15克、红花15克、桃仁15克、苏木10克、台乌15克、甘草6克、黄柏15克。
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| CN101757330A (zh) * | 2008-10-14 | 2010-06-30 | 赵赐安 | 一种治疗类风湿的复方内服散剂 |
| CN102188623A (zh) * | 2011-04-12 | 2011-09-21 | 郑延明 | 治疗风湿骨病的液体膏药及其制备方法 |
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| CN101757330A (zh) * | 2008-10-14 | 2010-06-30 | 赵赐安 | 一种治疗类风湿的复方内服散剂 |
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