CN102885964A - Traditional Chinese medicine composition with effect on clearing summer-heat and preparation method thereof - Google Patents
Traditional Chinese medicine composition with effect on clearing summer-heat and preparation method thereof Download PDFInfo
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- CN102885964A CN102885964A CN2011102034850A CN201110203485A CN102885964A CN 102885964 A CN102885964 A CN 102885964A CN 2011102034850 A CN2011102034850 A CN 2011102034850A CN 201110203485 A CN201110203485 A CN 201110203485A CN 102885964 A CN102885964 A CN 102885964A
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Abstract
The invention relates to a traditional Chinese medicine composition with an effect on clearing summer-heat. The traditional Chinese medicine composition comprises the following components in parts by weight: 170 to 240 parts of talcum powder, 15 to 40 parts of liquorice, 60 to 140 parts of sodium bicarbonate, 1 to 8 parts of borneol, 15 to 40 parts of lily, and 2 to 10 parts of peppermint. The traditional Chinese medicine composition provided by the invention has the effective components with functions of clearing summer-heat, maintaining acid-base balance of an organism, strengthening the heart and restoring consciousness, is free from toxic and side effects, and avoids the medicinal residues; and the traditional Chinese medicine composition is convenient to use, low in cost, high in prevention and treatment ratio of heatstroke and heat stress caused by high temperature and high humidity in summer.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of Chinese medicine composition with clearing away summer-heat function and preparation method thereof.
Background technology
Heat stress refers to the physiological reaction that animal body is replied the nonspecific defense in heat stress source, its essence is that finger ring border temperature such as surpasses at the summation of the nonspecific reaction due to the comfort zone ceiling temperature in the hot-zone.Heat stress on the impact of animal feed intake because of animal species, age with stress larger difference be arranged degree.It is generally acknowledged, heat stress often causes animal feed intake obviously to descend.When heat stress, because sympathetic activation, cause gastrointestinal motility to weaken, digestive juice secretion reduces, and digestive organs circulation volume reduces, gastrointestinal mucosa generation pathology damage causes gastrointestinal miopragia, the time of staying of food and extend in digestive tract makes in the gastrointestinal tract to fill, thus excited satiety center, suppress feeding center, animal feed intake is reduced.Under the heat stress state, because sympathetic activation and temperatures involved obviously raise body body temperature, respiratory frequency is obviously accelerated.The change of animal body physiological function is the result that the body neuro humor is regulated and the in-vivo tissue cell metabolism changes, and the animal body neuro humor is regulated and the in-vivo tissue cell metabolism changes the variation that must cause the body blood biochemical indicator, so a key character of changes of biochemical indexes substance in vivo metabolism and the variation of some histoorgan functional status when being the reflection heat stress of the animals.In recent years, free radical causes people's concern gradually in the effect that heat stress occurs.In the normal physiological situation, interior free yl produces and removing is in dynamic balance state, when animal is subject to heat stress, meeting so that the generation of free radical sharply increase, and the scarce capacity of free radical scavenging system causes interior free yl to accumulate, and causes the tissue oxidizing of animal impaired.Along with the continuous aggravation of global climate greenhouse effect and the development of highly intensive animal production, heat stress is produced animal and is caused serious adverse effect, has caused the great attention of vast livestock and poultry cultivation family, animal and veterinary worker, pharmaceutical producing enterprise.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition with clearing away summer-heat function, this Chinese medicine composition can shorten marketing time, promotes immunity, have no side effect, and drug residue can not occur, and is easy to use, cost is lower, and treatment rate is high and without drug dependence.
Another object of the present invention is to provide a kind of preparation method with Chinese medicine composition of clearing away summer-heat function.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine composition with clearing away summer-heat function, the component of its Chinese medicine composition and ratio of weight and number thereof are:
Pulvis Talci 170-240 part;
Radix Glycyrrhizae 15-40 part;
Sodium bicarbonate 60-140 part;
Borneolum Syntheticum 1-8 part;
Bulbus Lilii 15-40 part;
Herba Menthae 2-10 part.
And this Chinese medicine composition component and optimum ratio of weight and number thereof are respectively:
202 parts of Pulvis Talci;
22 parts in Radix Glycyrrhizae;
100 parts of sodium bicarbonate;
1 part of Borneolum Syntheticum;
20 parts of Bulbus Liliies;
5 parts of Herba Menthaes.
A kind of preparation method with Chinese medicine composition of clearing away summer-heat function, the step of its preparation method is:
(1). take by weighing respectively by weight ratio Pulvis Talci, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae and pulverize, and respectively all by the 80-100 mesh sieve;
(2). the Pulvis Talci after will sieving, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae are put into abundant mix homogeneously in the mixer, the Chinese medicine composition finished product that namely obtains having the clearing away summer-heat function.
Advantage of the present invention and beneficial effect are:
1. the Chinese medicine composition that originally has the clearing away summer-heat function contains Borneolum Syntheticum, Herba Menthae has refrigerant inducing sweat, and disperses wind heat, clearing throat, anti-inflammatory analgesic, the effect of heart tonifying refreshment, also have in addition simultaneously protect the liver, the effect such as function of gallbladder promoting, antiinflammatory, antibiotic, antiviral.
2. the Chinese medicine composition that originally has the clearing away summer-heat function contains Pulvis Talci, sodium bicarbonate can effectively replenish causes the body electrolyte losses because high temperature is perspired, thereby make body water-electrolyte metabolism balance, Radix Glycyrrhizae, Bulbus Lilii have relieve inflammation or internal heat, lung moistening, calm the nerves, the effect of eliminating phlegm and removing dampness.
3. the present invention has clearing away summer-heat, keeps the body acid-base balance, anti-stress, raising feed intake, shortens marketing time, promotes immunity, heart tonifying refreshment effective ingredient, have no side effect, and drug residue can not occur, easy to use, cost is lower, to because the prevention of the caused heatstroke of summer high-temperature high humidity, heat stress, treatment rate is high and without drug dependence.
The specific embodiment
The present invention is described in further detail by following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Pulvis Talci in the component of the present invention, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae all can be bought in market and obtain.
Embodiment 1
A kind of Chinese medicine composition with clearing away summer-heat function, component and the weight thereof of its Chinese medicine composition are respectively: Pulvis Talci 202Kg, Radix Glycyrrhizae 22Kg, sodium bicarbonate 100Kg, Borneolum Syntheticum 1Kg, Herba Menthae 5Kg, Bulbus Lilii 20Kg.
A kind of preparation method with Chinese medicine composition of clearing away summer-heat function, the step of its preparation method is as follows:
(1). take by weighing respectively by weight ratio Pulvis Talci, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae and pulverize, and respectively all by 80 mesh sieves;
(2). the Pulvis Talci after will sieving, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae are put into abundant mix homogeneously in the mixer, the Chinese medicine composition finished product that obtains having the clearing away summer-heat function.
Embodiment 2
A kind of Chinese medicine composition with clearing away summer-heat function, component and the weight thereof of its Chinese medicine composition are respectively: Pulvis Talci 170Kg, Radix Glycyrrhizae 15Kg, sodium bicarbonate 60Kg, Borneolum Syntheticum 1Kg, Herba Menthae 2Kg, Bulbus Lilii 16Kg.
The step of its preparation method is with embodiment 1.
Embodiment 3
A kind of Chinese medicine composition with clearing away summer-heat function, component and the weight thereof of its Chinese medicine composition are respectively: Pulvis Talci 240Kg, Radix Glycyrrhizae 40Kg, sodium bicarbonate 140Kg, Borneolum Syntheticum 7Kg, Herba Menthae 10Kg, Bulbus Lilii 40Kg.
The step of its preparation method is with embodiment 1.
Pulvis Talci 170-240 part;
Radix Glycyrrhizae 15-40 part;
Sodium bicarbonate 60-140 part;
Borneolum Syntheticum 1-8 part;
Bulbus Lilii 15-40 part;
Herba Menthae 2-10 part.
Embodiment 4
A kind of Chinese medicine composition with clearing away summer-heat function, component and the weight thereof of its Chinese medicine composition are respectively: Pulvis Talci 200Kg, Radix Glycyrrhizae 20Kg, sodium bicarbonate 100Kg, Borneolum Syntheticum 5Kg, Herba Menthae 20Kg, Bulbus Lilii 5Kg.
The step of its preparation method is with embodiment 1.
The present invention in use can stir the present invention in feedstuff, and after fully mixing, edible for domestic animal, every cattle is used 200g of the present invention at every turn, and every pig is used 50g of the present invention at every turn, once a day, is used in conjunction 5 days.
Clinical trial
1, first arrival in May, 2010 has been carried out clinical pharmacodynamics test of the present invention in 6 water cattle farms such as water cattle farms, Binyang County, Guangxi province Nanning City in by the end of September, 2010.Wherein the increase of matched group every increase by 100 every days 2kg ensilage is once drunk water; 100 every days of the loose group of common expelling summer-heat heat resistanceheat resistant, every water milch cow was used the loose 200g mixed feeding of expelling summer-heat heat resistanceheat resistant, normally fed, once a day; 1 group 110 of the present invention, 2 groups 101 of the present invention, 3 groups 102 of the present invention, 4 groups 103 of the present invention, the corresponding proportioning invention of this four groups of every days of every usefulness 200g mixed feeding is normally fed, once a day.Whole experimental session is treated altogether for 617 of heatstroke, heat stress symptom water milch cows.Operating position such as following table:
To heatstroke, heat stress case, treatment group administration of the present invention was cured 416 after 5 days, and cure rate reaches 97.42%.With SPSS12.0 statistics software analysis, behind the administration 5d, treatment group, the loose medication group of common expelling summer-heat heat resistanceheat resistant and matched group cure rate significant difference (p<0.05).
Investigation is found the every data in water cattle farm of carrying out the clinical pharmacodynamics test of the present invention are compared: the symptom that occurs heatstroke, heat stress behind use the present invention significantly disappears or alleviation, feed intake obviously rises, milk yield significantly improves, the fresh milk quality is obviously improved, through relevant departments' check drug residue free.Directly increased raiser's economic benefit, welcome by numerous raisers.
2, first arrival in June, 2010 in by the end of August, 2010, on pig farm, shop, Tian Jinshisi village, 5 pig farms such as pig farm, area just outside a city gate town, pig farm, Nan Cai town have carried out clinical pharmacodynamics test of the present invention, wherein increase the 0.5kg green vegetable in matched group every feedstuff 84 every days, increase once drinking-water, carry out 2 waterings for preventing heatstroke every day in the pig house, in time pig house cleaned; 84 every days of the loose group of common expelling summer-heat heat resistanceheat resistant, every pig was used the loose 50g mixed feeding of expelling summer-heat heat resistanceheat resistant, normally fed, once a day; 1 group 84 of the present invention, 2 groups 84 of the present invention, 3 groups 84 of the present invention, 4 groups 83 of the present invention, the corresponding proportioning invention of this four groups of every days of every usefulness 50g mixed feeding is normally fed, once a day.Whole experimental session is treated altogether for 503 of heatstroke, heat stress symptom pigs.
To heatstroke, heat stress case, after the treatment group administration of the present invention 5 times, cure 321, cure rate reaches 95.82%.With SPSS12.0 statistics software analysis, behind the administration 5d, use of the present invention group, use the loose medication group of common expelling summer-heat heat resistanceheat resistant and matched group cure rate significant difference (p<0.05).
Find in carrying out pharmacodynamics test process of the present invention, using a 2-3 of the present invention days feed intake to begin to increase, returned to normal level or significantly raising during by 5 days, use pig spirit of the present invention obviously to improve, weightening finish is remarkable.Having solved well raises pigs summer grows that existing heatstroke, heat stress are not eaten with causing, spirit is depressed even the situation of dead pig.Finding not occur drug residue to using pig of the present invention to carry out the pharmacokinetics check.To heightening raiser's income, shorten marketing time and be significantly increased.
The characteristic of particular components of the present invention:
Herba Menthae,, be born in by the hill wetland river for labiate " Herba Menthae " namely belongs to other dry herbs together " lunar caustic grass " more the popular name, and rhizome grows wild underground.The blue or green gas fragrance of Herb.Leaf is spent little lavender to life, and lip is spent the dark violet brown granule fruit of rear knot.Herba Menthae is one of Chinese conventional Chinese medicine.It is hot cold sweating antipyretic medicine, controls influenza, headache, conjunctival congestion, fever of the body, throat, the dental bed disease such as swell and ache.Herba Menthae contains volatile oil, is mainly I-menthol (I-menthol), 1-menthone (I-menthol) and Herba Menthae esters etc. in the oil.Oleum menthae is for oral administration to make skin capillary vascular expansion by the stimulating central nervous system system, promotes sweat gland secretion, increases heat radiation, and plays the sweating and heat resolving effect; Oleum menthae can suppress gastrointestinal smooth muscle and shrink, and can resist the acetic acid choline and presents spasmolysis; Oleum menthae can promote the respiratory tract glandular secretion and respiratory inflammation is had therapeutical effect; In vitro tests Herba Menthae decoct has inhibitory action to herpes simplex virus, forest virus, mumps virus, and staphylococcus aureus, Staphylococcus albus, alpha streptococcus, group B streptococcus, micrococcus catarrhalis, enteritis coccus, shigella flexneri, anthrax bacillus, diphtheria corynebacterium, Bacillus typhi, bacillus pyocyaneus, escherichia coli etc. are had bacteriostasis; The Oleum menthae external, the cold receptor of the tip that can excite nerve and produce creeping chill, and reflexive cause the variation of deep tissue blood vessel and play antiinflammatory, pain relieving, itching-relieving action.
Bulbus Lilii, Liliaceae lilium Latin language formal name used at school: Lilium brownii var.Viridulum.English name: Lily.Chinese another name: strong Qu, Flos Lilii viriduli, Bulbus lilii concoloris, the celestial being of falling.The main using value of Bulbus Lilii is to view and admire, and its napiform root contains and enriches starchiness, and it is edible that the part kind can be used as vegetable; With China's lanzhou lily that edibility is world-famous for, be documented in the earliest in the county annals of Pingliang, Gansu Province existing more than 450 year so far.The areas such as present Lanzhou Qi Lihe are the plantation edible lily extensively, enjoys high reputation at home and abroad.Lanzhou lily is individual greatly, flavor is sweet, both can make dessert, can make dish again; It is the good merchantable brand of relieving summer heat summer that the tiger lily in Yixing is made Lilii Decoction.Bulbus Lilii also can be made into dried lily bulb, Bulbus Lilii powder, and price is very high in the international market.Up to the present, Bulbus Lilii remains the medicinal herbs most in use in the Chinese medicine.The traditional Chinese medical science thinks that the Bulbus Lilii cold nature is flat, have relieve inflammation or internal heat, lung moistening, the effect of calming the nerves, its flower, the squamous stem all can be used as medicine, and is a kind of flowers of dietotherapeutic.Lily bulb contains the multiple alkaloid such as colchicine and starch, protein, fat etc. and the flower pesticide of Lilium longiflorum contains multiple types carotene, and wherein major part is along antheraxanthin ester (Cis-Antheraxanthin esters), accounts for 91.7%~94%.The traditional Chinese medical science is thought nourishing YIN and moistening the lung, clearing away heart-fire for tranquillization.Be used for deficiency of YIN chronic cough, sputum mixed with blood, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep, absentminded.Have nourishing YIN and moistening the lung cough-relieving effect, be used for the cough caused by dryness-heat of deficiency of lung-YIN, sputum mixed with blood is such as all sorts of flowers cream.Control chronic cough of deficiency lung, the chronic cough spitting of blood has the clearing away heart-fire for tranquillization effect such as baihe gujin decoction, is used for the calentura waste heat unclear, fidgets due to deficiency palpitation with fear, insomnia and dreamful sleep etc.Studies show that: the Lipid composition of medicine Bulbus Lilii, lanzhou lily, Lilium longiflorum is take the content of cardiolipin and phosphorus fatty acid as main. cough-relieving, eliminate the phlegm, antiasthmatic effect, Bulbus Lilii water extraction liquid is to mouse stomach, the cough latent period that sulfur dioxide is drawn cough prolongs, and the cough number of times reduces; Phenol red output, significantly increased. the Bulbus Lilii decoct has antitussive action to the mouse cough that ammonia causes, white mice lung perfusion increases flow; And the Bufo siccus asthma that can cause antihistamine. the effect Bulbus Lilii of the rising peripheral leukocytes peripheral leukocytes that can raise, and being improved the effect of immunity of organisms. experiment shows: the Bulbus Lilii gavage can prevent caused by cyclophosphamide animal white cytopenia. other effects: Bulbus Lilii, Bulbus Lilii, tiger lily water extraction liquid can make pentobarbital sodium prolong the length of one's sleep to mouse stomach; Can suppress significantly the delayed hypersensitivity of DNFB (DNCB) induced mice; But the swimming time of significant prolongation " insufficiency of lung-QI " type mice has resisting fatigue usefulness, still can make the load swimming time significant prolongation of " deficiency of YIN " model mice due to the adrenal cortex, and tiger lily and Bulbus Lilii make mice load swimming time significant prolongation; Hypoxia endurance time under the tiger lily water extraction liquid gavage energy significant prolongation mice normal pressure, Bulbus Lilii water extraction liquid gavage has the effect that prolongs its hypoxia endurance time to the mice under the myocardial oxygen consumption increase state due to isoproterenol.
Claims (3)
1. Chinese medicine composition with clearing away summer-heat function, it is characterized in that: the component of this Chinese medicine composition and ratio of weight and number thereof are:
Pulvis Talci 170-240 part;
Radix Glycyrrhizae 15-40 part;
Sodium bicarbonate 60-140 part;
Borneolum Syntheticum 1-8 part;
Bulbus Lilii 15-40 part;
Herba Menthae 2-10 part.
2. the Chinese medicine composition with clearing away summer-heat function according to claim 1, it is characterized in that: this Chinese medicine composition component and optimum ratio of weight and number thereof are respectively:
202 parts of Pulvis Talci;
22 parts in Radix Glycyrrhizae;
100 parts of sodium bicarbonate;
1 part of Borneolum Syntheticum;
20 parts of Bulbus Liliies;
5 parts of Herba Menthaes.
3. preparation method with Chinese medicine composition of clearing away summer-heat function as claimed in claim 1, it is characterized in that: the step of this preparation method is:
(1). take by weighing respectively by weight ratio Pulvis Talci, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae and pulverize, and respectively all by the 80-100 mesh sieve;
(2). the Pulvis Talci after will sieving, Radix Glycyrrhizae, sodium bicarbonate, Borneolum Syntheticum, Bulbus Lilii, Herba Menthae are put into abundant mix homogeneously in the mixer, the Chinese medicine composition finished product that namely obtains having the clearing away summer-heat function.
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN103948722A (en) * | 2014-04-30 | 2014-07-30 | 武汉华扬动物药业有限责任公司 | Traditional Chinese medicinal composition for preventing and treating animal heat stress and preparation method thereof |
CN108261496A (en) * | 2016-12-31 | 2018-07-10 | 天津瑞贝特科技发展有限公司 | Prevent Chinese medicine composition of heat stress and preparation method thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101297860A (en) * | 2007-09-07 | 2008-11-05 | 天津生机集团有限公司 | Chinese medicinal composition for preventing and controlling heat stress and heatstroke of birds |
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Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN101297860A (en) * | 2007-09-07 | 2008-11-05 | 天津生机集团有限公司 | Chinese medicinal composition for preventing and controlling heat stress and heatstroke of birds |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103948722A (en) * | 2014-04-30 | 2014-07-30 | 武汉华扬动物药业有限责任公司 | Traditional Chinese medicinal composition for preventing and treating animal heat stress and preparation method thereof |
CN103948722B (en) * | 2014-04-30 | 2016-06-29 | 武汉华扬动物药业有限责任公司 | Chinese medicine composition of preventing and treating heat stress of the animals and preparation method thereof |
CN108261496A (en) * | 2016-12-31 | 2018-07-10 | 天津瑞贝特科技发展有限公司 | Prevent Chinese medicine composition of heat stress and preparation method thereof |
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Application publication date: 20130123 |