CN102879593B - Multichannel liquid sample reagent rapid charging reactor - Google Patents
Multichannel liquid sample reagent rapid charging reactor Download PDFInfo
- Publication number
- CN102879593B CN102879593B CN201110192340.5A CN201110192340A CN102879593B CN 102879593 B CN102879593 B CN 102879593B CN 201110192340 A CN201110192340 A CN 201110192340A CN 102879593 B CN102879593 B CN 102879593B
- Authority
- CN
- China
- Prior art keywords
- sample
- reagent
- rotating shaft
- reactor
- hole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention discloses a multichannel liquid sample reagent rapid charging reactor which comprises two parts of a sample reagent charging device and a preset first reagent cuvette. A piece of plastic slab in the sample reagent charging device is provided with multipath sample reagent dosing holes with equal spacing. The holes are corresponding to a rotating shaft sample communication groove on a rotating shaft in the sample reagent charging device. A liquid passes through via holes on the rotating shaft and is introduced into end sample conducting holes. Through rotation of the rotating shaft and a centrifugation method, a sample reagent is rapidly introduced into the preset first reagent colorimetric ware through the end sample via holes. The sample and reagent are mixed and react. And results of each projects are determined through apparatuses. By the adoption of the charging reactor, the range of measured projects is increased. Sample application accuracy is not influenced by precision of a sample injector. The operation process is simple. The charging reactor provided by the invention is especially suitable for human emergency biochemical detection, basic medical unit biochemical detection and animal biochemical detection, and can also be applied in other fields such as immunology, microbiology, molecular biology and the like.
Description
Technical field
The present invention relates to field of medical examination, be specifically related to a kind of Multi-channel liquid sample reagent reactor of annotating fast.
Background technology
In clinical biomedical check field, biochemical investigation occupies sizable proportion.The check of current clinical biochemical both at home and abroad is mainly applied automatically or semi-automatic biochemical analyzer detects.In these two kinds of biochemical instruments, also according to methodology principle, be divided into wet type and dry type biochemical instruments.But these instruments adopt single channel single channel and single channel much channel communication application of sample, reagent adding more.Namely instrument can only with a suction needle draw singly sample join in reaction cup or dry type analoids on, in wet type biochemical instruments, also in reaction cup, add one by one a kind of to several reagent.And the amount of each sample or reagent is incomplete same, require the driver part of suction needle and suction reagent needles very accurate.Instrument will constantly be adjusted and inhale sample and inhale amount of reagent action according to methodological requirement simultaneously.Therefore can make the generation of the problems such as the complex structure of instrument, precision is high, cost is high, efficiency is low.
At present dry type biochemical instruments mainly relies on import, because the technical requirement of dry type analoids is high, and domestic dry type biochemical instruments and the analoids that there is no Yi Jia factory can the required biochemical investigation project of overall production.Instrument and the reagent of most dependence on import, cost is very high.Be difficult to apply in economically less developed region and grass-roots unit.Some large hospitals are mainly due to emergency treatment biochemical investigation.
Summary of the invention
The object of the present invention is to provide a kind of Multi-channel liquid sample reagent reactor of annotating fast, the problem such as solved liquid sample charging point complex structure in prior art, precision is high, cost is high, efficiency is low.
A kind of Multi-channel liquid sample reagent of the present invention reactor of annotating fast, it is characterized in that, comprise that sample reagent filling apparatus and preset the first reagent cuvette two large divisions form, a plastic plate in described sample reagent filling apparatus is provided with the sample reagent dosing hole that multichannel spacing is equal, in described sample reagent filling apparatus, be also provided with a cylinder-shaped shaft, by being located at the rotating shaft of end, can automatically carry out radial rotary by artificial or machine, rotation is to appropriate location, in rotating shaft, have a rotating shaft sample connectivity slot and several rotating shaft sample vias, rotating shaft is also provided with several end sample vias, the quantity of described end sample via is corresponding with the quantity of sample reagent dosing hole, the spacing of end sample via in rotating shaft also equates, the quantity of preset the first reagent cuvette is corresponding with the quantity of end sample conduction pipe, described end sample via leads to preset the first reagent cuvette.
Preferably, when only measuring for liquid list sample, described sample reagent dosing hole comprises the multichannel spacing equal sample dosing hole corresponding with rotating shaft sample connectivity slot; When measuring for liquid double reagent, described sample reagent dosing hole also comprises the multichannel spacing equal reagent quantitative hole corresponding with rotating shaft sample connectivity slot.
Preferably, the volume in the sample dosing hole in described sample reagent filling apparatus and reagent quantitative hole is within the scope of 2-100ul; Sample dosing hole in described sample reagent filling apparatus and the quantity in reagent quantitative hole are a hole, 2 holes to 50.
Preferably, described preset the first reagent cuvette, by making by the plastics of ultraviolet light.
Compared with prior art, the present invention has the following advantages:
1. only need once to annotate, just can complete the filling process of a plurality of project samples simultaneously;
2. the degree of accuracy of application of sample fixes volume by prefabricated sample dosing hole kapillary, is not subject to sample injector Accuracy;
3. operating process is very simple, and any layman can complete operation.
4. both can also can measure project with double reagent with single reagent, increase the scope of the project of measuring, and use liquid reagent to save in a large number cost.
5. be specially adapted to the mankind's emergency treatment biochemical investigation, basic medical unit biochemical investigation and animal biochemical investigation, can also be applied to other, as fields such as immunology, microbiology, molecular biology, there is larger expanded application and be worth.
Accompanying drawing explanation
Fig. 1 is annotate the fast structural representation of reactor of the Multi-channel liquid sample reagent of measuring for single reagent of the present invention.
Fig. 2 is annotate the fast rotating shaft first sense of rotation schematic diagram of reactor of the Multi-channel liquid sample reagent of measuring for single reagent of the present invention.
Fig. 3 is annotate the fast rotating shaft second sense of rotation schematic diagram of reactor of the Multi-channel liquid sample reagent of measuring for single reagent of the present invention.
Fig. 4 is annotate the fast structural representation of reactor of the Multi-channel liquid sample reagent of measuring for double reagent of the present invention.
Fig. 5 is the Multi-channel liquid sample reagent of measuring for double reagent of the present invention reactor rotating shaft the 3rd sense of rotation schematic diagram of annotating fast.
Fig. 6 is the Multi-channel liquid sample reagent of measuring for double reagent of the present invention reactor rotating shaft the 4th sense of rotation schematic diagram of annotating fast.
Number in the figure explanation: 1. sample dosing hole, 2. reagent quantitative hole, 3. sample reagent filling apparatus, 4. rotating shaft, 5. end sample via, 6. preset the first reagent cuvette, 7. rotating shaft sample connectivity slot, 8. rotating shaft sample via, 9. rotating shaft reagent via.
Embodiment
Embodiment 1
As shown in Figure 1, a kind of sample reagent that can measure for single reagent of the present invention reactor of annotating fast, comprises sample reagent filling apparatus 3, in sample reagent filling apparatus 3 the sample dosing hole 1 that multichannel spacing is equal is set on a transparent plastic sheet.In sample dosing hole 1 lower end, be provided with the rotating shaft 4 of a cylindrical horizontal placement, in rotating shaft 4, have a rotating shaft sample connectivity slot 7 and rotating shaft sample via 8, below rotating shaft 4, on transparent plastic sheet, have the end sample via 5 corresponding with rotating shaft sample via 8.When rotating shaft sample connectivity slot 7 is aimed at each sample dosing hole 1 lower end, with the top from the sample dosing hole 1 at middle part after common sample-sucking device imbitition sample, add sample, sample can be full of each sample dosing hole 1 by capillarity, thereby completes application of sample process.By rotating shaft 4, from single reagent rotating shaft the first sense of rotation shown in Fig. 2, turn clockwise 90 °, rotate to single reagent rotating shaft the second sense of rotation shown in Fig. 3, then, whole reactive system device is put into hydro-extractor, with centrifugal method, the sample in each hole is flowed in preset the first reagent cuvette 6 by rotating shaft sample via 8 and end sample road through hole 5, sample and reagent mix reaction, by the result of Instrument measuring projects.
Wherein, the setting parameter of sample dosing hole 1, is the different analytical parameters according to each pilot project, uses cylinder volume computing method, obtains the volume of each sample dosing hole 1, according to different volumes, manufactures each required sample dosing hole 1.
Embodiment 2
As shown in Figure 4, a kind of sample reagent that can measure for double reagent of the present invention reactor of annotating fast, architecture basics at the reactor of annotating fast for the sample reagent of single reagent mensuration, on transparent plastic sheet in sample reagent filling apparatus 3, be also provided with the multichannel spacing equal reagent quantitative hole 2 corresponding with sample dosing hole 1, the corresponding rotating shaft reagent via 9 that is provided with in rotating shaft 4, rotating shaft reagent via 9 is also corresponding with end sample via 5.
When during use, double reagent is measured biochemical project, first the rotating shaft sample connectivity slot in rotating shaft 47 is aimed to the lower end of each sample dosing hole 1, then at a sample dosing hole 1 that is arranged in middle part, till filling it up with the slow injecting sample of sample to each sample dosing hole 1 of common sample injector absorption q.s.In Fig. 5, the angle state of the lower end aligned rotating shaft sample connectivity slot 7 of sample dosing hole 1 rotating shaft 4 during for application of sample, then from the 3rd sense of rotation shown in Fig. 5, counterclockwise rotating shaft is rotated, rotating shaft turns 30 ° of left and right clockwise, position to the 4th sense of rotation shown in Fig. 6, the lower end of sample dosing hole 1 and rotating shaft sample via 8, the lower end aligned rotating shaft reagent via 9 in reagent quantitative hole 2, makes reagent import end sample via 5.Then whole reactive system device is put into hydro-extractor, sample and reagent are thoroughly entered in pre-Sheng the first reagent cuvette 6, and fully mix with reagent.Take out reactive system device and put into the result that instrument is measured each project.
Wherein, the setting parameter in sample dosing hole 1 and reagent quantitative hole 2, the different analytical parameters according to each pilot project, use cylinder volume computing method, obtain each sample dosing hole 1 and reagent quantitative hole 2 volume, according to different volumes, manufacture each required sample dosing hole 1 and reagent quantitative hole 2.
Above-described embodiment is just to allow one of ordinary skilled in the art can understand content of the present invention and implement according to this for technical conceive of the present invention and feature being described, its objective is, can not limit the scope of the invention with this.Every equivalent variation or modification that according to the present invention, the essence of content has been done, all should be encompassed in protection scope of the present invention.
Claims (7)
1. the Multi-channel liquid sample reagent reactor of annotating fast, it is characterized in that, comprise that sample reagent filling apparatus (3) and preset the first reagent cuvette (6) two large divisions form, a plastic plate in described sample reagent filling apparatus (3) is provided with the sample reagent dosing hole that multichannel spacing is equal, in described sample reagent filling apparatus (3), be also provided with a rotating shaft (4), in rotating shaft (4), have a rotating shaft sample connectivity slot (7) and several rotating shaft sample vias (8), rotating shaft (4) is also provided with several end sample vias (5), described end sample via (5) leads to preset the first reagent cuvette (6).
2. the Multi-channel liquid sample reagent according to claim 1 reactor of annotating fast, is characterized in that, described rotating shaft (4) is cylindrical, by being located at the rotating shaft of end, carries out radial rotary.
3. the Multi-channel liquid sample reagent according to claim 1 reactor of annotating fast, it is characterized in that, described sample reagent dosing hole comprises the sample dosing hole (1) that the multichannel spacing corresponding with rotating shaft sample connectivity slot (7) is equal, and described sample reagent dosing hole also comprises the reagent quantitative hole (9) that the multichannel spacing corresponding with rotating shaft sample connectivity slot (7) is equal.
4. the Multi-channel liquid sample reagent according to claim 3 reactor of annotating fast, is characterized in that, the sample dosing hole (1) in described sample reagent filling apparatus (3) and the volume of reagent quantitative hole (9) are within the scope of 2-100ul.
5. the Multi-channel liquid sample reagent according to claim 3 reactor of annotating fast, is characterized in that, the sample dosing hole (1) in described sample reagent filling apparatus (3) and the quantity of reagent quantitative hole (9) are a hole, 2 holes to 50.
6. the Multi-channel liquid sample reagent according to claim 1 reactor of annotating fast, is characterized in that, described preset the first reagent cuvette (6), by making by the plastics of ultraviolet light.
7. the Multi-channel liquid sample reagent according to claim 1 reactor of annotating fast, it is characterized in that, the quantity of described end sample via (5) is corresponding with the quantity of sample reagent dosing hole, the spacing of end sample via (5) in rotating shaft (4) is also equal, and the quantity of preset the first reagent cuvette (6) is corresponding with the quantity of end sample via (5).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110192340.5A CN102879593B (en) | 2011-07-11 | 2011-07-11 | Multichannel liquid sample reagent rapid charging reactor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110192340.5A CN102879593B (en) | 2011-07-11 | 2011-07-11 | Multichannel liquid sample reagent rapid charging reactor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102879593A CN102879593A (en) | 2013-01-16 |
| CN102879593B true CN102879593B (en) | 2014-09-03 |
Family
ID=47480991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110192340.5A Active CN102879593B (en) | 2011-07-11 | 2011-07-11 | Multichannel liquid sample reagent rapid charging reactor |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102879593B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110887960B (en) * | 2019-12-02 | 2021-11-02 | 电子科技大学 | Urine test strip quantitative detection system and method based on machine vision |
| CN117347648B (en) * | 2023-12-05 | 2024-02-09 | 广东省良种引进服务公司 | Automatic detection system for fish oil components |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2702313Y (en) * | 2004-06-11 | 2005-05-25 | 中国科学院力学研究所 | Biological chip production and chip-on biomolecule fixing and detection integrated system |
| CN1705884A (en) * | 2002-10-28 | 2005-12-07 | 爱科来株式会社 | Analyzing tool and device |
| EP1722236A1 (en) * | 1999-02-16 | 2006-11-15 | Applera Corporation | Bead dispensing system |
| CN101375169A (en) * | 2006-01-13 | 2009-02-25 | 环球生物研究株式会社 | Distortive dispensing chip, distortive dispensing apparatus and method of distortive dispensing processing |
-
2011
- 2011-07-11 CN CN201110192340.5A patent/CN102879593B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1722236A1 (en) * | 1999-02-16 | 2006-11-15 | Applera Corporation | Bead dispensing system |
| CN1705884A (en) * | 2002-10-28 | 2005-12-07 | 爱科来株式会社 | Analyzing tool and device |
| CN2702313Y (en) * | 2004-06-11 | 2005-05-25 | 中国科学院力学研究所 | Biological chip production and chip-on biomolecule fixing and detection integrated system |
| CN101375169A (en) * | 2006-01-13 | 2009-02-25 | 环球生物研究株式会社 | Distortive dispensing chip, distortive dispensing apparatus and method of distortive dispensing processing |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102879593A (en) | 2013-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102253230B (en) | Automatic analyzer and analysis method of blood platelets | |
| CN102680545B (en) | Test instrument for detecting electrolyte item and total carbon dioxide | |
| WO2022110574A1 (en) | Liquid injection and suction device for measurement chamber | |
| CN102879593B (en) | Multichannel liquid sample reagent rapid charging reactor | |
| CN204613163U (en) | For detecting the system of dry blood sample | |
| CN203132865U (en) | Puncturing piston type sample feeding and sampling device | |
| CN203241404U (en) | Automatic multi-parameter chemical reagent filling device of water quality online analyzer | |
| CN104515768A (en) | Tumor specific growth factor detection kit | |
| CN201364336Y (en) | Dedicated metering device for automatic water quality analyzer | |
| CN102262082B (en) | Optical fiber sensor-molecular imprinting online detection method for detecting propofol in biological samples and optical fiber sensor-molecular imprinting online detection device. | |
| CN204758619U (en) | Accurate sampling system based on accurate syringe pump | |
| CN204028091U (en) | A kind of novel Platelet function Analyzer of multiparameter fast | |
| CN103543279B (en) | Portable quantitative detecting device for blood | |
| CN201803983U (en) | Sensor electrode of blood gas electrolytic analyzer | |
| CN204649479U (en) | Be applicable to the multifunction sampling pond of fermented sample process | |
| CN104034761B (en) | A kind of device and method detecting OBP and pheromone cohesive process | |
| CN202814969U (en) | Disposable type consumable for matched handheld type rapid detection analysis device | |
| CN202516571U (en) | Inspection test tube | |
| CN208003973U (en) | A kind of use for laboratory organic reagent quantifies liquid-transfering device | |
| CN109307769B (en) | Preparation method of 12mmol/L blood glucose solution | |
| CN202599846U (en) | Group detection device and kit for clinical biochemical samples | |
| CN103808949B (en) | A kind of Fully-automatic production line type trace element detector | |
| Sewart et al. | Microfluidic device for fast on-site biomedical diagnostic on the example of lithium analysis in blood | |
| CN104865099A (en) | Multifunctional sampling tank suitable for fermented sample treatment | |
| CN202036222U (en) | Disposable micro-blood sampler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201104 Address after: High tech Zone Branch Road, Suzhou city of Jiangsu Province, No. 18 215163 Patentee after: Suzhou Zhongjia Kangmei Technology Co.,Ltd. Address before: Huqiu Victoria Garden District of Suzhou City, Jiangsu province 215000 building 12 Room 601 Patentee before: Zhang Zhaolin |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220420 Address after: Room 303-2, building 2, No. 1, Qingshan Road, high tech Zone, Suzhou, Jiangsu 215163 Patentee after: Suzhou kangjianyun Medical Technology Co.,Ltd. Address before: 215163 No.18 Kechuang Road, high tech Zone, Suzhou City, Jiangsu Province Patentee before: Suzhou Zhongjia Kangmei Technology Co.,Ltd. |
|
| TR01 | Transfer of patent right |