CN102872425A - Chinese medicinal decoction for treating climacteric syndrome - Google Patents

Abstract

The invention discloses a Chinese medicinal decoction for treating climacteric syndrome. The decoction is prepared from the following Chinese medicinal raw materials by weight: 30g of astragalus root, 15g of red ginseng, 12g of bighead atractylodes rhizome, 12g of sharpleaf galangal fruit, 15g of yam, 15g of kudzuvine root, 9g of golden cypress, 6g of rhizoma anemarrhenae, 9g of peony bark, 12g of lilyturf root, 12g of glossy privet fruit, 12g of eclipta alba, 9g of divaricate saposhnikovia root, 9g of dried tangerine peel, 6g of hemp, 15g of white peony root, 15g of medicinal cyathula root, 20g of mother-of-pearl, 15g of spina date seed, 12g of Chinese thorowax root, 12g of turmeric root-tuber, 12g of silk tree albizzia bark, 30g of blighted wheat, 10g of Chinese date, 6g of rose, 20g of sweet wormwood herb, and 15g of Chinese wolfberry root-bark. The decoction can effectively treat symptoms in a patient with climacteric syndrome, such as paroxysmal heat, flushing, palpitation, amnesia, irritability, sweat, loose stool, general edema, fatigue, dizziness and the like, is remarkable in curative effect, and worthy of clinical popularization.

Description

A kind of Chinese medicine decoction for the treatment of climacteric syndrome

Technical field

The present invention relates to a kind of Chinese medicine decoction for the treatment of climacteric syndrome.

Background technology

Climacteric syndrome be climacteric occur a series of take autonomic nervous dysfunction as main symptom, comprise menoxenia, paroxysmal dizziness, headache, cardiopalmus, forgetful, irritated irritability, sweating, just sugar, edema, fatigue and weakness etc., belong to " menopausal syndrome ", " dirty dry " category of motherland's medical science.Traditional Chinese Medicine is many to be controlled from the kidney opinion, thinks that climacteric syndrome is deficiency of kidney-QI, and menses declines few, so that imbalance between YIN and YANG causes.Therefore when treatment, take the kidney invigorating gas, regulating YIN and YANG as main method.

Summary of the invention

The object of the present invention is to provide a kind of Chinese medicine decoction for the treatment of climacteric syndrome.

Its technical solution is:

A kind of Chinese medicine decoction for the treatment of climacteric syndrome, it is that raw material of Chinese medicine by following weight portion is made: Radix Astragali 30g, Radix Ginseng Rubra 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Alpiniae Oxyphyllae 12g, Rhizoma Dioscoreae 15g, Radix Puerariae 15g, Cortex Phellodendri 9g, Rhizoma Anemarrhenae 6g, Cortex Moutan 9g, Radix Ophiopogonis 12g, Fructus Ligustri Lucidi 12g, Herba Ecliptae 12g, Radix Saposhnikoviae 9g, Pericarpium Citri Reticulatae 9g, Rhizoma Cimicifugae 6g, Radix Paeoniae Alba 15g, Radix Cyathulae 15g, Concha Margaritifera 20g, Semen Ziziphi Spinosae 15g, Radix Bupleuri 12g, Radix Curcumae 12g, Cortex Albiziae 12g, Fructus Tritici Levis 30g, Fructus Jujubae 10g, Flos Rosae Rugosae 6g, Herba Artemisiae Annuae 20g, Cortex Lycii 15g.

Above-mentioned Chinese medicine decoction can be prepared as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water is advisable to surpass liquid level 2～3cm; Enter to fry in shallow oil and front above-mentioned raw material of Chinese medicine is soaked half an hour, make it fully moistening, fully fried in order to medicine juice; Then (suddenly) fire of useing force boils, and uses literary composition (little) fire instead again and decocts.Stop when decocting about 15 minutes, remove medicinal residues, get decoction.

Processed with wine Cortex Phellodendri and the processed with wine Rhizoma Anemarrhenae that above-mentioned Cortex Phellodendri and the Rhizoma Anemarrhenae preferably adopt wine processing to form.Can adopt following method to concoct such as the processed with wine Cortex Phellodendri: get the Cortex Phellodendri sheet, add yellow wine and mix thoroughly, vexed, use the slow fire fried dry, take out, cool.Per 100 kilograms of Cortex Phellodendri sheets are with 10 kilograms of yellow wine.

Pharmacology of the present invention and effect are as follows:

Climacteric syndrome is more common in the women, " all diseases before and after the menopause ", " dirty dry " category of belonging to motherland's medical science, common people are many to be controlled from the kidney opinion, and taste do not cause enough attention to the understanding of primary disease, and spleen is " the foundation of acquired constitution, source of generating QI and blood ", " husband's stomach is reservoir of food and drink; diet enters stomach, transporting essential substances in solution, on fail in spleen; Spleen-QI transporting the essence to the whole body, on be attributed to lung; Regulating fluid apssage, lower defeated bladder; Crystal's four cloth, the Five Classics is parallel, closes in 4 o'clock, the five internal organs, negative and positive, estimates and often thinks also." (Li Dongyuan " Treatise on the spleen and stomach ").Involutional symptom and the weakness of the spleen and stomach such as sweating, dizziness and tinnitus, dysphoria, palpitation and insomnia, spiritlessness and weakness warmed, the YIN-fire upper punch is relevant; Coldheat complex be " QI of the spleen and stomach is dirty, essence derived from food must not be risen floating, is that making of spring life is not all right, and then depletion of YANG one protects its Rong Wei, does not then appoint wind and cold, be give birth to cold and heat, this all due to the QI of the spleen and stomach deficiency also." (Li Dongyuan " Treatise on the spleen and stomach ").Spleen is " the foundation of acquired constitution, source of generating QI and blood ".And the women is take blood as this, therefore from the Treatise on the spleen and stomach disease of effecting a permanent cure.Weakness of the spleen and stomach is the important pathogenesis of primary disease, and menopausal women is because weakness of the spleen and stomach, the biochemical weary source of QI and blood, and battalion defending imbalance and causing the gradually minimizing of menses until exhaust, and menstruation subtracts disconnected, a series of pathological changes of lacking of proper care of internal organs negative and positive of qi and blood occur.Such as " Ling Shu Miraculous Pivot or Divine Axis battalion health meeting " cloud: " people is bullied in paddy, and paddy enters stomach, to pass in lung; the vital organs of the human body are all to be bullied; it please the person be battalion, and turbid person seeks in arteries and veins; defend in arteries and veins for defending; seek week endlessly ... the old's QI and blood declines, and muscle is withered, stagnant QI-passage, mutual disturbances among ZANG-QI, its deficiency of nutrient QI with inner disturbance of defensive QI ".And " YIN-fire " word in the taste YIN-fire sees Li Dongyuan " Treatise on the spleen and stomach ", the febrile disease that has embodied weakness of the spleen and stomach arises from the moon, in fire is born in, the pathological characteristic that healthy energy is empty, why be referred to as YIN-fire, because it is different from our common hyperactivity of fire caused by deficiency of YIN disease of setting forth or excess-heat disease, can not promote yang-energy owing to weakness of the spleen and stomach, make the fire of the physiology of internal organs can not normally exercise its function, so turn the fire of pathology into, in disturb the vital organs of the human body, as Li Dongyuan institute cloud " deficiency of spleen-QI and stomach-QI; then dirty in kidney, YIN-fire are taken advantage of the soil position ".Through cloud: temperature can be except large hot.Treatment is mended and wherein risen its sun when with the sweet agent of suffering, and is sweet cold to rush down its fiery spontaneous recovery also.Therefore quasi-complement spleen QI invigorating heat extraction decoction is treated this disease, wherein clear sun is given birth in the sweet temperature gas supplementing spleen invigorating of the medicines such as the Radix Astragali, Radix Ginseng Rubra, Rhizoma Dioscoreae, Radix Puerariae; Invigorating the spleen and replenishing QI, the heart nourishing palpitation stabilizings such as GANMAI DAZAO TANG, Semen Ziziphi Spinosae, Concha Margaritifera; Insufficiency of the spleen liver wants to take advantage of it, and the Radix Paeoniae Alba, Flos Rosae Rugosae, Radix Bupleuri, Cortex Albiziae etc. are with the easing the affected liver resolving depression; The go well with wine Rhizoma Anemarrhenae processed, Radix Ophiopogonis, processed with wine Cortex Phellodendri, Cortex Lycii, Herba Artemisiae Annuae clearind deficient heat; Fructus Ligustri Lucidi, Herba Ecliptae kidney-yang nourishing; The Radix Cyathulae conducting blood to flow downwards; Rhizoma Cimicifugae is the guiding drug of taste warp; The empty endogenous dampness of easily giving birth to of taste, the Pericarpium Citri Reticulatae regulating QI and lowering the adverseness is dry; Radix Saposhnikoviae has wind energy to win wet effect.Play altogether strengthening the spleen and stomach, clearind deficient heat, easing the affected liver and nourish heart full side.Transporting and transforming function of the spleen and stomach is normal, and then QI and blood is prosperous, and the vital organs of the human body are moistened foster, and it is normal that function is recovered.And according to wherein Radix Ginseng Rubra of modern pharmacological research, Rhizoma Dioscoreae, Radix Puerariae, Radix Achyranthis Bidentatae, GANMAI DAZAO TANG, Fructus Ligustri Lucidi, Herba Ecliptae etc. estrogen-like effects is arranged.So eliminate after the we treatment that such patient's tactical deployment of troops is warmed, flushed complexion, cardiopalmus, forgetful, irritated irritability, sweating, just sugar, edema, fatigue and weakness and the symptoms such as dizzy, evident in efficacy, the clinic popularization.

Clinical data:

Choose 2008.06-2012.07 and go to a doctor in Qingdao of Shandong province Huangdao District hospital of traditional Chinese hospital department of Chinese medicine outpatient service climacteric syndrome patient 200 examples, be divided at random two groups and treat, matched group 100 examples wherein, treatment group 100 examples; The conventional application of matched group Radix Et Caulis Acanthopanacis Senticosi tablet, oryzanol treatment, treatment group add on the treatment basis of matched group with decoction treatment of the present invention.

Clinical efficacy

Group number of cases is cured the routine number invalid routine number effective percentage of routine number that takes a turn for the better

Treatment group 100 61 30 9 91.0%

Matched group 100 51 24 25 75.0%

Statistical method has carried out date processing with the SPSS10.0 statistical software.Data represent with means standard deviation.Relatively adopt the t check between two groups, the relatively employing X 2 test of rate.There is statistical significance P＜0.05 for difference.

The result: there is the statistics difference treatment group P＜0.05 of comparing with matched group.The cure rate for the treatment of group, improvement rate and total effective rate all are higher than matched group, illustrate that treatment group adds on the basis for the treatment of of control group that to treat climacteric syndrome with decoction of the present invention evident in efficacy, is worth further clinical expansion.

Model case:

Case 1

Patient Zhang, the woman, 53 years old, paroxysmal dizziness, sweating, flushed face 3 months, companion's dysphoria, indigestion and loss of appetite, refreshing tired weak, to sleep poor, there are indentation white and thin fur, deep and weak pulse in the light red tongue limit.In the past healthy, menopause half a year.Have a medical check-up: T36,1 ℃ of BP120/80mmHg, mind is clear, and face is flushing slightly, and two pulmonary respiration sounds are clear, and heart rate 70 times/minutes is restrained regularly, and hear sounds is strong, remaining (-).Pathogenesis: deficiency of spleen-QI, disturb on the interior-heat, irritability, the rule for the treatment of: spleen invigorating QI invigorating clearind deficient heat is calmed the nerves, square medicine: decoction of the present invention, potion divided and sooner or later took every day, took rear further consultation of a week, and the patient states, and above-mentioned symptom obviously alleviates, imitate more not square, continued to take 1 week after, symptom disappears substantially, the decoction of stopping using.Advise the patient to take BUZHONG YIQI WAN 6gbid and consolidate curative effect.

Case 2

Patient Xue, woman, 48 years old, patient's identification number 008712.The patient was admitted to hospital October 12 in 2011 because of " paroxysmal cardiopalmus half a year ", and the companion is irritated, sweating, and the uneasiness of sleeping, there is the indentation thin fur on the light red tongue limit, and root is slightly yellow, deep and weak pulse.Have a medical check-up: mind is clear, and two pulmonary respiration sounds are clear, heart rate 78 times/minute, to restrain regularly, hear sounds is strong, and abdomen is soft, and two lower limb are without edema.Previously healthy, menstruation irregularis half remaining year.Look into thyroid function, blood glucose, Color Sonography after being admitted to hospital without unusually, blood fat: T-CHOL 6,1mmol/L, low density lipoprotein, LDL 3,75mmol.Electrocardiogram: sinus rate, lead ST-T more and change.Give quiet DANHONG ZHUSHEYE 40ml and enter liquid qd, oral bisoprolol 2,5mgqd treat after 5 days symptom without improvement, require to take traditional Chinese medicine decoction.Inscribe and see: agitation, sweating, fatigue in both spirit and physical strength, flushed face, the uneasiness of sleeping, the tongue arteries and veins is the same, pathogenesis: deficiency of spleen-QI, interior-heat disturbing the mind upwards, the rule for the treatment of: spleen invigorating QI invigorating clearind deficient heat, tranquilizing by nourishing the heart, square medicine: decoction of the present invention, day potion, minute early, evening clothes, take 5 days after, above-mentioned symptom alleviates, the uneasiness of still sleeping, night, dream was many, and the top adds Poria cum Radix Pini 12g, Radix Angelicae Sinensis 15g, Arillus Longan 12g calms the nerves with replenishing blood for nourishing heart, and sleep takes a turn for the better after three doses, continuing takes five doses, and patient's symptom disappears substantially, the decoction of stopping using.Advise the patient to take Renshen Guipi Wan 1 ball bid and consolidate curative effect.

The specific embodiment

A kind of Chinese medicine decoction for the treatment of climacteric syndrome, it is that raw material of Chinese medicine by following weight portion is made: Radix Astragali 30g, Radix Ginseng Rubra 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Alpiniae Oxyphyllae 12g, Rhizoma Dioscoreae 15g, Radix Puerariae 15g, processed with wine Cortex Phellodendri 9g, processed with wine Rhizoma Anemarrhenae 6g, Cortex Moutan 9g, Radix Ophiopogonis 12g, Fructus Ligustri Lucidi 12g, Herba Ecliptae 12g, Radix Saposhnikoviae 9g, Pericarpium Citri Reticulatae 9g, Rhizoma Cimicifugae 6g, Radix Paeoniae Alba 15g, Radix Cyathulae 15g, Concha Margaritifera 20g, Semen Ziziphi Spinosae 15g, Radix Bupleuri 12g, Radix Curcumae 12g, Cortex Albiziae 12g, Fructus Tritici Levis 30g, Fructus Jujubae 10g, Flos Rosae Rugosae 6g, Herba Artemisiae Annuae 20g, Cortex Lycii 15g.

The preparation method of above-mentioned Chinese medicine decoction is as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water is advisable to surpass liquid level 2～3cm; Enter to fry in shallow oil and front above-mentioned raw material of Chinese medicine is soaked half an hour, make it fully moistening, fully fried in order to medicine juice; Then (suddenly) fire of useing force boils, and uses literary composition (little) fire instead again and decocts.Stop when decocting about 15 minutes, remove medicinal residues, get decoction.

Claims (1)

1. Chinese medicine decoction for the treatment of climacteric syndrome is characterized in that it is that raw material of Chinese medicine by following weight portion is made: Radix Astragali 30g, Radix Ginseng Rubra 15g, Rhizoma Atractylodis Macrocephalae 12g, Fructus Alpiniae Oxyphyllae 12g, Rhizoma Dioscoreae 15g, Radix Puerariae 15g, Cortex Phellodendri 9g, Rhizoma Anemarrhenae 6g, Cortex Moutan 9g, Radix Ophiopogonis 12g, Fructus Ligustri Lucidi 12g, Herba Ecliptae 12g, Radix Saposhnikoviae 9g, Pericarpium Citri Reticulatae 9g, Rhizoma Cimicifugae 6g, Radix Paeoniae Alba 15g, Radix Cyathulae 15g, Concha Margaritifera 20g, Semen Ziziphi Spinosae 15g, Radix Bupleuri 12g, Radix Curcumae 12g, Cortex Albiziae 12g, Fructus Tritici Levis 30g, Fructus Jujubae 10g, Flos Rosae Rugosae 6g, Herba Artemisiae Annuae 20g, Cortex Lycii 15g.