CN102866112B - Six-freedom-degree micro-fluidic control chip absorption spectrum detection support - Google Patents
Six-freedom-degree micro-fluidic control chip absorption spectrum detection support Download PDFInfo
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- CN102866112B CN102866112B CN201210342169.6A CN201210342169A CN102866112B CN 102866112 B CN102866112 B CN 102866112B CN 201210342169 A CN201210342169 A CN 201210342169A CN 102866112 B CN102866112 B CN 102866112B
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Abstract
The invention discloses a six-freedom-degree micro-fluidic control chip absorption spectrum detection support which is used for the detecting and testing absorbance of a micro-fluidic chip, and the support is provided with an x-directional detection supporting arm, a y-directional detection supporting arm and a z-directional supporting arm, wherein the x-directional, y-directional and the z-directional supporting arms respectively support a corresponding x-directional detection connecting arm, a y-directional detection connecting arm and a z-directional detection connecting arm, the middle position of the support is fixedly connected with four micro-fluidic chip loading arms, the x-directional detection connecting arm, the y-directional detection connecting arm and the z-directional connecting arm are respectively, correspondently and fixedly connected with every two of x-directional, y-directional and z-directional detection optical-fiber loading arms, the micro-fluidic chip loading arm is a hollow tube internally sleeved with a telescopic connecting arm, and an extension end of the telescopic connecting arm is connected with a micro-fluidic chip loading clamp; each detection optical-fiber loading arm is a hollow tube internally sleeved with a telescopic-type crank arm, the extension end of the telescopic-type crank arm is a hollow tube internally sleeved with a telescopic collimation mirror loading arm, the extension end of the telescopic collimation mirror loading arm is fixedly connected with a collimation mirror connecting bushing, and the collimation mirror connecting bushing is connected a collimation mirror which is connected with an optical fiber; and multi-angle detection can be simultaneously conducted on the micro-fluidic chip, and the universality is good.
Description
Technical field
The present invention relates to micro-fluidic chip absorption spectrum Bracket for Inspection, when micro-fluidic chip absorbance detection is tested, use.
Background technology
Microfluidic chip system is to only having the new technology of test on the chip of several centimetres with analysis by biological, chemical experiment process micro.Absorbance determination method is a kind of maturation and reliable analytical approach, and according to statistics, the material that accounts for material total amount 80% all has to ultraviolet or visible ray the response of absorption, and Absorbance detection method has advantages of that can to measure substance classes many, simple in structure.Therefore the micro-fluidic chip absorbance detection technology, micro-fluidic chip being combined with absorbance determination method becomes domestic and international study hotspot gradually.In order to realize the absorbance detection experiment of micro-fluidic chip, Chinese scholars is all the absorbance detection support according to designed microfluidic chip structure design specialized at present, and special-purpose absorbance detection support can not be transplanted the absorbance detection for other micro-fluidic chips.Yet, the absorbance detection of micro-fluidic chip can be divided into longitudinal detection and axially detect, and different chip structure, detection position also varies, the needs that some micro-fluidic chips exist multichannel absorbance detection to carry out even simultaneously simultaneously, all will redesign micro-fluidic chip Bracket for Inspection has expended a large amount of human and material resources and financial resources at every turn, and the design of support simultaneously need to be carried out after micro-fluidic chip has designed, and has so just caused the waste of experimental period.
Summary of the invention
While the object of the invention is for current micro-fluidic chip absorbance detection experiment, the poor defect of Bracket for Inspection versatility, has proposed a kind of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection.The optional position that this support can be adjusted to luminous source optical fiber and detection fiber access point micro-fluidic chip comprises lengthwise position and axial location, has the total space range of adjustment of six degree of freedom, and the detection of micro-fluidic chip absorbance is had to good versatility.
For achieving the above object, the technical scheme of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection is: this support has x, y, z to detecting sway brace, be supported with respectively corresponding x, y, z to detecting linking arm, the medium position of support is fixedly connected with four micro-fluidic chips of four jiaos that are respectively used to clamp micro-fluidic chip and carries dress arm, x, y, z is carried dress arm to detecting on linking arm corresponding respectively each two x, y, z that are fixedly connected with to detection fiber, and every two the described detection fiber on equidirectional are carried the both sides that dress arm is arranged in micro-fluidic chip; It is the hollow tubular that inner sleeve has telescopic linking arm that described micro-fluidic chip carries dress arm, and the external part of telescopic linking arm connects micro-fluidic chip and carries clamping; Described x, y, z is carried dress arm to detection fiber and is inner sleeve and has telescopic hollow tubular of cranking arm, telescopic external part of cranking arm is the hollow tubular that the telescopic collimating mirror of inner sleeve carries dress arm, the external part that telescopic collimating mirror carries dress arm is fixedly connected with collimating mirror joint sleeve, and collimating mirror joint sleeve connects the collimating mirror joining with optical fiber; During detection, collimating mirror is relative with micro-fluidic chip check point entrance and exit and be close to.
The present invention compares with technology with existing method, and tool has the following advantages:
1, the present invention can carry out the absorbance detection of multi-angle simultaneously to micro-fluidic chip.Solve traditional absorption spectrum Bracket for Inspection and can not to micro-fluidic chip, carry out a difficult problem for multi-angle detection simultaneously.
2, the present invention can adjust arbitrarily detection position according to the structure of micro-fluidic chip, has solved the poor shortcoming of traditional micro-fluidic chip absorption spectrum Bracket for Inspection versatility.
3, the present invention adopts a kind of portable bridge to take structure, simple in structure, simple to operate, easy to use, has stronger portability.
4, measurement scale adjusting mechanism of the present invention adopts a kind of engagement anti-skid structure, and the detection position fixing can, because changed by extraneous factor, not guarantee to detect the precision of data.
5, each several part of the present invention is flexible connection, is convenient to the expansion that optical fiber carries dress arm, and the multiple spot that can realize in same dimension detects simultaneously.
Accompanying drawing explanation
Fig. 1 is the one-piece construction schematic diagram of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection;
Fig. 2 is the structural representation that in Fig. 1, micro-fluidic chip carries dress arm 4;
Fig. 3 is that in Fig. 1, y carries the structural representation of dress arm 9 to detection fiber;
Fig. 4 is that in Fig. 3, y carries the structure cut-open view of the collimating mirror 18 on dress arm 9 to detection fiber;
Fig. 5 be in Fig. 1 y to the connection diagram that detects linking arm 3 one end and integral support 1: Fig. 5 (a) is front elevation, and Fig. 5 (b) is left view;
Fig. 6 is the use view of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection;
The sequence number of each parts and title in accompanying drawing: 1. integral support body; 2.y is to detecting sway brace; 3.y is to detecting linking arm; 4. micro-fluidic chip carries dress arm; 5.x is to detecting linking arm; 6.z is to detecting sway brace; 7.z is to detecting linking arm; 8.x is to detecting sway brace; 9.y carries dress arm to detection fiber; 10.z carries dress arm to detection fiber; 11.x carries dress arm to detection fiber; 12. micro-fluidic chips carry clamping; 13. tension springs; 14. telescopic cranking arm; 15. fixed screws; 16. telescopic collimating mirrors carry dress arm; 17. collimating mirror joint sleeves; 18. collimating mirrors; 19. simple lenses; 20. collimating mirror outward turning mouths; 21. collimating mirror inward turning mouths; 22.y is to the engaging tooth detecting on sway brace 2; 23. engagement shaft collars; 24. fixed knobs; 25. rotary screws; 26.y is to the inward turning tooth that detects linking arm 3; 27. light sources; 28. spectrometers; 29. computing machines; 30. fixed screws; 31. install the telescopic linking arm that micro-fluidic chip carries clamping 12; 32. micro-fluidic chips; 33. fixed screws; 34,35. optical fiber.
Embodiment
Referring to Fig. 1, it is a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection one-piece construction schematic diagram.The one-piece construction of support of the present invention adopts steel frame construction, guarantees the stability of duty.Support 1 is frame type structure, and the medium position of support 1 is fixed with four micro-fluidic chips and carries dress arm 4, four micro-fluidic chips and carry dress arm 4 and be respectively used to clamp 32 4 jiaos of micro-fluidic chips.On support 1, there is x to detecting sway brace 8, y is to detecting sway brace 2 and z to detecting sway brace 6, be respectively used to support corresponding x to detecting linking arm 5, y to detecting linking arm 3 and z to detecting linking arm 7, and can be fixed and be supported in optional position, x is to detecting linking arm 5, y to detecting linking arm 3 and z to detecting linking arm 7 at orthogonal space.X is correspondingly respectively fixedly connected with two x and to detection fiber, carries dress arm 11, two y and carry dress arm 9 and two z carry dress arm 10 to detection fiber to detection fiber to detecting on linking arm 7 to detecting linking arm 3 and z to detecting linking arm 5, y.Two x carry dress arm 11, two y to detection fiber and carry dress arm 9 and two z carry dress arm 10 for loading transmitting and detection fiber to detection fiber to detection fiber, and the detection fiber on every two equidirectionals is carried dress arm and be arranged on the both sides of micro-fluidic chip 32 in its direction, can realize the absorption spectrum of micro-fluidic chip 32 on x, y, z any direction and measure.
Referring to Fig. 1 and Fig. 2, Fig. 2 carries the structural representation of dress arm 4 for inventing a kind of micro-fluidic chip of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection.In Fig. 2, micro-fluidic chip carries dress arm 4 for hollow tubular, in it, be set with the telescopic linking arm 31 that carries clamping 12 for micro-fluidic chip is installed, telescopic linking arm 31 can carry the axial direction slip of dress arm 4 and be fixed in micro-fluidic chip by the screw 30 that is tightened along micro-fluidic chip and carry on dress arm 4.Fluidic chip carries on the external part that clamping 12 is fixed on telescopic linking arm 31, and fluidic chip carries clamping 12 inside tension spring 13 is installed, and for guaranteeing that fluidic chip carries clamping 12 and possesses certain folder power, micro-fluidic chip is clamped.
Referring to Fig. 1 and Fig. 3, Fig. 3 is that the y of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection carries the structural representation of dress arm 9 to detection fiber.It is hollow tubular that optical fiber carries dress arm 9, is set with telescopicly to crank arm 14 in it, and telescopic 14 axial directions that can carry dress arm 9 along optical fiber of cranking arm move and fix by fixed screw 33.Telescopic 14 the flexibility of cranking arm is 90 °, telescopic 14 the external part of cranking arm is hollow tubular, in it, be set with telescopic collimating mirror and carry dress arm 16, telescopic collimating mirror carries dress arm 16 and can move and fix by fixed screw 15 along telescopic 14 the axial direction of cranking arm.The external part that telescopic collimating mirror carries dress arm 16 is installed with collimating mirror joint sleeve 17, and there is screw thread collimating mirror joint sleeve 17 inside for collimating mirror 18 is installed.X carries dress arm 11 and z to detection fiber and to detection fiber, carries dress arm 10 and y and to detection fiber, carry that to fill the structure of arm 9 identical.
Referring to Fig. 1, Fig. 3 and Fig. 4, Fig. 4 is that the y of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection carries the structure cut-open view of the collimating mirror 18 on dress arm 9 to detection fiber.Collimating mirror 18 inside are provided with simple lens 19 for incident light being converged into parallel light emergence, the head outside of collimating mirror 18 have screw thread be collimating mirror outward turning mouth 20 for collimating mirror being mounted to collimating mirror joint sleeve 17, it is that collimating mirror inward turning mouth 21 is for being mounted to optical fiber collimating mirror 18 that the afterbody of collimating mirror 18 inner side has screw thread.
Referring to Fig. 1 and Fig. 5, the y of a kind of six degree of freedom micro-fluidic chip of Fig. 5 the present invention absorption spectrum Bracket for Inspection is to the connection diagram that detects linking arm 3 one end and integral support 1: be divided into Fig. 5 (a) and Fig. 5 (b), wherein Fig. 5 (a) is its front elevation; Its left view of Fig. 5 (b).As shown in the figure, y is twin columns structure to detecting sway brace 2, between twin columns, there is engagement shaft collar 23, twin columns inner side arranges horizontal engaging tooth 22, engaging tooth 22 can form the firm state of engagement with the engaging tooth 32 meshing on shaft collar 23, engagement shaft collar 23 gaps are set in rotary screw 25 outsides, and the medial aperture of engagement shaft collar 23 is greater than rotary screw 25 to such an extent as to engagement shaft collar 23 does not rotate with rotary screw 25.One end of rotary screw 25 and y are connected to screw thread 26 formation that detect in linking arm 3, and the other end of rotary screw 25 is fixed with knob 24, and the external diameter of fixed knob 24 is greater than the internal diameter of engagement shaft collar 23.When fixed knob 24 rotation, can at y, to detecting the interior rotation of linking arm 3, move ahead by driven rotary screw mandrel 25, rotate to after some scale, because the external diameter of fixed knob 24 is greater than the internal diameter of engagement shaft collar 23, therefore fixed knob 24 can compress with y engagement shaft collar 23 to detecting sway brace 2 engagements, thereby effectively prevent that y is loosening to detecting linking arm 3, and then impact detects effect.Y is identical with connected mode and the said structure of integral support 1 to detecting linking arm 3 other ends; X is identical with syndeton and said structure with integral support 1 to detecting linking arm 7 to detection linking arm 5, z.In addition, the each several part of this support 1 is flexible connection, and same support boom can install many linking arms additional, and the multiple spot of realizing in same dimension detects simultaneously.
Referring to Fig. 6, Fig. 6 is a specific embodiment of a kind of six degree of freedom micro-fluidic chip of the present invention absorption spectrum Bracket for Inspection.Micro-fluidic chip 32 to be detected needs z to detection, by till adjusting telescopic linking arm 31 and being adjusted to and can clipping to micro-fluidic chip 32.The screw 30 that is tightened is fixing by telescopic linking arm 31.Micro-fluidic chip 32 is clipped on to micro-fluidic chip and carries clamping 12.Adjust z and make the mouth to be detected of its position and micro-fluidic chip 32 on same straight line to detecting linking arm 7, and be fixed.Adjusting z carries dress arm 10 to detection fiber to make its telescopic collimating mirror carry the position of collimating mirror 18 on dress arm relative with micro-fluidic chip 32 check point entrance and exits and be close to.The collimating mirror 18 that optical fiber carries dress arm 10 upsides joins with optical fiber 34, and collimating mirror 18 and the optical fiber 35 of downside join.Optical fiber 34 is connected with light source 27, and optical fiber 35 is connected with spectrometer 28, and spectrometer 28 connects computer 29.Open light source 27, spectrometer 28 and computer 29 and just can gather and analyze the absorption spectrum signal of micro-fluidic chip along z to check point.
Claims (5)
1. a six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection, this support has x, y, z is to detecting sway brace (8, 2, 6), be supported with respectively corresponding x, y, z is to detecting linking arm (5, 3, 7), it is characterized in that: the medium position of support is fixedly connected with four micro-fluidic chips of four jiaos that are respectively used to clamp micro-fluidic chip (32) and carries dress arm (4), x, y, z is to detecting linking arm (5, 3, 7) corresponding each two x that are fixedly connected with respectively on, y, z carries dress arm (11 to detection fiber, 9, 10), every two described detection fiber on equidirectional are carried dress arm (11, 9, 10) be arranged in the both sides of micro-fluidic chip (32), described micro-fluidic chip carries the hollow tubular of dress arm (4) telescopic linking arm (31) for inner sleeve has, and the external part of telescopic linking arm (31) connects micro-fluidic chip and carries clamping (12), described x, y, z is carried dress arm (11,9,10) to detection fiber and is the hollow tubular that inner sleeve has telescopic cranking arm (14), the external part of telescopic cranking arm (14) is the hollow tubular that the telescopic collimating mirror of inner sleeve carries dress arm (16), the external part that telescopic collimating mirror carries dress arm (16) is fixedly connected with collimating mirror joint sleeve (17), and collimating mirror joint sleeve (17) connects the collimating mirror (18) joining with optical fiber, during detection, collimating mirror (18) is relative with micro-fluidic chip (32) check point entrance and exit and be close to.
2. a kind of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection according to claim 1, it is characterized in that: described detection sway brace is twin columns structure, between twin columns, there is engagement shaft collar (23), twin columns inner side is provided with and the engaging tooth (22) that meshes shaft collar (23) engagement, engagement shaft collar (23) coaxial space cover has rotary screw (25), rotary screw (25) one end connects with corresponding described detection linking arm, rotary screw (25) other end connecting external diameter is greater than the fixed knob (24) of engagement shaft collar (23) internal diameter, fixed knob (24) can compress engagement shaft collar (23) and the engagement of detection sway brace.
3. a kind of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection according to claim 1, is characterized in that: collimating mirror (18) inside is provided with simple lens (19), head outside is provided with and connects the collimating mirror outward turning mouth (20) of collimating mirror joint sleeve (17), the collimating mirror inward turning mouth (21) that afterbody inner side is provided with installing optical fibres.
4. a kind of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection according to claim 1, it is characterized in that: telescopic collimating mirror carries dress arm (16) and can move and fix by fixed screw along the axial direction of telescopic cranking arm (14), telescopic cranking arm (14) can along optical fiber carry dress arm (9) axial direction move and fix by another fixed screw, the flexibility of telescopic cranking arm (14) is 90 °.
5. a kind of six degree of freedom micro-fluidic chip absorption spectrum Bracket for Inspection according to claim 1, it is characterized in that: telescopic linking arm (31) can along micro-fluidic chip carry dress arm (4) axial direction move and fix by fixed screw, fluidic chip carries clamping (12) inside and is provided with tension spring (13).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210342169.6A CN102866112B (en) | 2012-09-17 | 2012-09-17 | Six-freedom-degree micro-fluidic control chip absorption spectrum detection support |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210342169.6A CN102866112B (en) | 2012-09-17 | 2012-09-17 | Six-freedom-degree micro-fluidic control chip absorption spectrum detection support |
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| CN102866112A CN102866112A (en) | 2013-01-09 |
| CN102866112B true CN102866112B (en) | 2014-12-03 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104849222B (en) * | 2015-01-23 | 2018-01-16 | 江苏大学 | The micro-fluidic apparatus for measuring concentration of rotation dish-style and method based on photometric detection |
| CN105784611B (en) * | 2016-03-04 | 2018-08-10 | 江苏大学 | Multiple-unit integration test apparatus and method based on micro-fluidic chip photometric detection |
Citations (4)
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|---|---|---|---|---|
| CN1556371A (en) * | 2004-01-02 | 2004-12-22 | 清华大学 | Multifunction tridimension displacement laser interference measuring system |
| CN101520415A (en) * | 2008-02-29 | 2009-09-02 | 中国科学院大连化学物理研究所 | Micro-fluidic laser-induced fluorescence detector with functions of automatic positioning and focusing |
| CN201532188U (en) * | 2009-10-17 | 2010-07-21 | 山东工商学院 | Laser intelligent detecting instrument for microfluidic chip |
| CN102589422A (en) * | 2011-12-16 | 2012-07-18 | 哈尔滨工业大学 | Orthogonal light path two-dimensional micro-focus collimation and three-dimensional coordinate sensor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002061400A1 (en) * | 2001-01-31 | 2002-08-08 | Sau Lan Tang Staats | Optical detection system for chromatographic and electrokinetic liquid phase separations |
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Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1556371A (en) * | 2004-01-02 | 2004-12-22 | 清华大学 | Multifunction tridimension displacement laser interference measuring system |
| CN101520415A (en) * | 2008-02-29 | 2009-09-02 | 中国科学院大连化学物理研究所 | Micro-fluidic laser-induced fluorescence detector with functions of automatic positioning and focusing |
| CN201532188U (en) * | 2009-10-17 | 2010-07-21 | 山东工商学院 | Laser intelligent detecting instrument for microfluidic chip |
| CN102589422A (en) * | 2011-12-16 | 2012-07-18 | 哈尔滨工业大学 | Orthogonal light path two-dimensional micro-focus collimation and three-dimensional coordinate sensor |
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