CN105784611B - Multiple-unit integration test apparatus and method based on micro-fluidic chip photometric detection - Google Patents
Multiple-unit integration test apparatus and method based on micro-fluidic chip photometric detection Download PDFInfo
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Abstract
The present invention discloses a kind of multiple-unit integration test apparatus and method based on micro-fluidic chip photometric detection, with multiple independent submodules, the photometric detection light-emitting tube for being fixed with photometric detection reception pipe on the bottom plate of the upper chamber of the shell of each submodule, being fixed on top plate right over photometric detection reception pipe, it is horizontal glass objective table between detection light-emitting tube and photometric detection reception pipe, glass objective table puts micro-fluidic chip on upper surface；Master controller sends signal to selection circuit module, select the working condition of each unit main control chip module started or stopped, control signal is sent by the unit main control chip module of selection work to start to work by photometric detection optical receiver module, photometric detection optical transmitter module and temperature sensor, temperature sensor detects the temperature of current micro-fluidic chip local environment and feeds back to main control chip module in real time；Each unit module can be manipulated individually simultaneously, and testing inspection while multi-chip may be implemented.
Description
Technical field
It is specifically a kind of based on micro-fluidic photometric detection the present invention relates to photometric detection and micro-fluidic chip detection technique
Experimental rig.
Background technology
Photometric detection technology is also known as molecular spectrum detection method, is a kind of optical detection means, it is to utilize detecting instrument
（Such as spectrophotometer）Absorbance is carried out in a certain specific wavelength or certain wave-length coverage to detected material either to send out
The detection of luminous intensity.Photometric detection is a kind of qualitative or quantitative detection method, and is simple and convenient to operate, examines with instrument
The features such as quick is surveyed, is had a wide range of applications in fields such as actual materialogy, surface chemistry, physics and hydrodynamics.
In detection method of microfluidic chip, the integration characteristics of photoelectric detecting method are best, and wherein photometry is pervasive
The optimal method of property.However, currently based on micro-fluidic photometric detection device, such as China Patent No. CN201510034319.0
It is also uncontrollable cannot to provide the operating environment in darkroom, photometric detection environment temperature for designed photometric detection device in document, and
And it is bulky, it can not achieve portable, these are limited to a certain extent based on the extensive of micro-fluidic photometric detection device
It uses.Therefore, a kind of photometric detection device portable with dark room conditions, temperature-controllable, device how is designed to have become at present
The problem of micro-fluidic photometric detection field urgent need to resolve.
Invention content
The purpose of the present invention is for integrated journey existing for the photometric detection experimental rig currently based on micro-fluidic chip
The problems such as low, environment is uncontrollable is spent, a kind of integrated experimental rig of multiple-unit based on micro-fluidic photometric detection of proposition and side
Method provides dark room conditions, realizes that environment is controllable and compact-sized easy to carry.
The present invention is based on the multiple-unit integration test device of micro-fluidic chip photometric detection the technical solution adopted is that：Have
The outside of multiple independent submodules, each submodule is shell, and the enclosure of each submodule is separated by one piece of diaphragm plate
At upper and lower two chambers, it is fixed with photometric detection reception pipe on the bottom plate of upper chamber, is fixed on top plate and is connect positioned at photometric detection
Photometric detection light-emitting tube right over closed tube, it is horizontal glass loading to detect between light-emitting tube and photometric detection reception pipe
Platform, puts micro-fluidic chip on glass objective table upper surface, glass objective table left end by the left plate of left slideway connected with outer casing,
Right end is placed with temperature sensor, on the shell chamber by the right plate of right slideway connected with outer casing on glass loading edge of table
Chamber interior is equipped with heating plate and the first partition for the rectangle arranged vertically with interval from front to back, second partition, third partition board
With the 4th partition board, first partition and second partition are located at the front of photometric detection light-emitting tube, second partition and third partition board position
In the rear of photometric detection light-emitting tube, the left plate of the left end of every piece of partition board all with shell upper chamber is sealedly and fixedly connected, often
Right plate of the right end of block partition board all with shell upper chamber is sealedly and fixedly connected；The top of first partition and third partition board with outside
The top plate of shell upper chamber is closely coupled, bottom with there are gaps between upper chamber bottom surface；The bottom of second partition and the 4th partition board
There are gap, top in portion with glass objective table, and there are gaps, fan to be located at first partition between the top plate of shell upper chamber
Upper front part and be fixed on shell upper chamber top plate；The lower chambers of each shell are internally provided with photometric detection light-receiving mould
Block, photometric detection optical transmitter module, main control chip module and fan and heating plate control module, wherein any one submodule
The lower chambers of shell be internally provided with master controller and selection circuit module, it is defeated that master controller output end connects selection circuit module
Enter end, selection circuit module output end is separately connected the input terminal of each main control chip module；Each main control chip module passes through
Different ports is separately connected the photometric detection optical receiver module for belonging to the same submodule, photometric detection optical transmitter module, temperature
Spend sensor and fan and heating plate control module.
The present invention is based on the technologies that the test method of the multiple-unit integration test device of micro-fluidic chip photometric detection uses
Scheme is：It is characterized in that including the following steps：
A, glass objective table is slided by left slideway and right slideway and is pulled out, place the micro-fluidic chip of sample introduction, led to
It crosses left slideway and right slideway and glass objective table is slided into push-in；
B, master controller sends signal to selection circuit module, selects starting or stopping for each unit main control chip module
Working condition：
C, control signal is sent by the unit main control chip module of selection work to examine by photometric detection optical receiver module, luminosity
It surveys optical transmitter module and temperature sensor is started to work, photometric detection optical receiver module controls the bright dark of photometric detection light-emitting tube
Its collected signal of institute is sent to main control chip mould by degree, photometric detection light receiving tube by photometric detection optical receiver module
Block, temperature sensor detect the temperature of current micro-fluidic chip local environment and feed back to main control chip module in real time.
Further, in the submodule where the unit main control chip module by selection work, temperature sensor is by institute
The environment temperature of detection inputs main control chip module, and main control chip module is by the environment temperature of detection and preset standard temperature
Range comparison is spent, if necessary to adjust temperature, then controls corresponding fan and heating plate work through fan and heating plate control module
Make, realizes that temperature is adjusted.
The present invention has the following advantages that compared with existing methods and techniques：
（1）Experimental rig of the present invention is by N（N>=4）A separate unit module composition, each unit module can simultaneously individually into
Row manipulation, may be implemented testing inspection while multi-chip, the micro-fluidic chip towards multi-form, single testing site.
（2）Experimental rig of the present invention provides the experimental enviroment in darkroom, by the setting for the sandwich plate that misplaces, completely cuts off well
External light source, effectively shields stray light.
（3）Experimental rig of the present invention realizes temperature-controllable within a certain error range, passes through fan, heating plate and dislocation
The air flow channel that sandwich plate is formed provides suitable temperature for detection environment.
（4）Experimental rig of the present invention realizes wavelength variable photometric detection, by replacing the transmitting tube in inner top
Realize the experiment of different wave length.
（5）Experimental rig of the present invention can facilitate the positioning of photometric detection, pass through objective table mark testing site and Array analysis
The manual alignment positioning of point.
（6）Test method of the present invention is easy to operate, it is only necessary to position chip placement can control device be detected.
（7）Experimental rig small volume of the present invention, it is easy to carry, facilitate displacement.
Description of the drawings
Fig. 1 is the overall structure signal of the multiple-unit integration test device the present invention is based on micro-fluidic chip photometric detection
Figure；
Fig. 2 is the structural schematic diagram of the first common micro-fluidic chip in Fig. 1；
Fig. 3 is the structural schematic diagram of second of common micro-fluidic chip in Fig. 1；
Fig. 4 is the structural schematic diagram of the third common micro-fluidic chip in Fig. 1.
Fig. 5 is the process schematic of the glass objective table sliding push-pull in Fig. 1；
Fig. 6 is the assembling structure enlarged diagram of photometric detection reception pipe 5 and photometric detection light-emitting tube 18 in Fig. 1；
Fig. 7 is the arrangement enlarged diagram of upper chamber's internal fan of shell in Fig. 1, heating plate and partition board；
Fig. 8 is fan in Fig. 7, heating plate and baffle arrangement principle right view；
Fig. 9 is structure enlargement diagram inside the lower chambers of shell in Fig. 1；
Figure 10 is the control block diagram of Fig. 1.
The serial number and title of each component in attached drawing：1. control shows touch screen, 5. photometric detection light receiving tubes, 9. left cunnings
Road, 10. right slideways, 14. glass objective tables, 18. photometric detection light-emitting tubes, 22. fans, 26. testing sites, 30,31,34,35,
36,39,40,41,42. chip sample delivery points, 32,38,44. Array analysis points, 33,37,43. chip stream sample channels, 45. is micro-fluidic
Chip, 46. shells, 48. first partitions, 49. second partitions, 50. third partition boards, 51. the 4th partition boards, 52. heating plates, 53. electricity
Conversion module is pressed, 54. photometric detection optical receiver modules, 55. photometric detection optical transmitter modules, 57. main control chip modules, 58. touch
Touch screen display control module, 59. control module circuit boards, 60. fans and heating plate control module, 61. temperature sensors, 62.
Round small slot, 63. truckles, 64. master controllers, 65. selection circuit modules.
Specific implementation mode
Referring to Fig. 1, it is total that the present invention is based on the overall structure of the multiple-unit integration test device of micro-fluidic chip photometric detection
There are multiple independent submodules, the quantity N of submodule（N>=4）, 4 independent submodules, multiple submodules are illustrated only in Fig. 1
Block from left to right arrange by "-" type, and align.The outside of each submodule is the shell 46 of opaque sealing, adjacent two
A side plate is shared between a shell 46, such as：The right plate of the shell 46 of second submodule and third submodule it is outer
The left plate of shell 46 shares.
Upper and lower two chambers are separated by one piece of diaphragm plate inside the shell 46 of each submodule, on the bottom plate of upper chamber
Photometric detection reception pipe 5 is fixed, is fixed with photometric detection light-emitting tube 18 and fan 22 on the top plate of upper chamber, wherein luminosity
Detection light-emitting tube 18 is located at the surface of photometric detection reception pipe 5.Detection light-emitting tube 18 and photometric detection reception pipe 5 it
Between be horizontal glass objective table 14, put micro-fluidic chip 45,45 shape of micro-fluidic chip on 14 upper surface of glass objective table
Size is no more than 14 appearance and size of glass objective table, and there are one testing site 26, testing site 26 and luminosity for tool on micro-fluidic chip 45
Light-emitting tube 18, about 5 face of photometric detection reception pipe are detected, the center of three is located on same vertical line.Glass objective table
14 are equipped with alignment mark point, which is overlapped with the testing site 26 on micro-fluidic chip 45, positioned with this.Glass carries
14 left end of object platform passes through 10 connected with outer casing of right slideway by the left plate of 9 connected with outer casing 46 of left slideway, 14 right end of glass objective table
46 right plate, glass objective table 14 are slid back and forth by left slideway 9 and right slideway 10 along shell 46, realize glass objective table 14
Slide back and forth push-and-pull, convenient displacement micro-fluidic chip 45 manually.Touch screen is installed on the front side board of the lower chambers of shell 46
1, realize man-machine communication.
The structure of the common micro-fluidic chip 45 of the first shown in Figure 2, the micro-fluidic chip 45 be two sample delivery points,
The rectangle micro-fluidic chip of one testing site has chip sample delivery point 30, chip sample delivery point 31, Array analysis point 32 and chip stream sample
Channel 33.Test solution is entered by chip sample delivery point 30 and chip sample delivery point 31 respectively, flows through chip stream sample channel 33, reaches chip
32 hybrid reaction of testing site.
The structure of second of common micro-fluidic chip 45 shown in Figure 3, the micro-fluidic chip 45 be three sample delivery points,
The rectangle micro-fluidic chip of one testing site has chip sample delivery point 34, chip sample delivery point 35, chip sample delivery point 36, Array analysis
Point 38 and chip stream sample channel 37, test solution are entered by chip sample delivery point 34, chip sample delivery point 35, chip sample delivery point 36 respectively,
Chip stream sample channel 37 is flowed through, 38 hybrid reaction of Array analysis point is reached.
The structure of the third common micro-fluidic chip 45 shown in Figure 4, the micro-fluidic chip 45 be four sample delivery points,
The disc micro-fluidic chip of one testing site, have chip sample delivery point 39, chip sample delivery point 40, chip sample delivery point 41, chip into
Sampling point 42, Array analysis point 44 and chip stream sample logical 43, Array analysis point 44 is located at centre, and four sample delivery points are distributed in Array analysis
The surrounding of point 44, test solution pass through chip sample delivery point 39, chip sample delivery point 40, chip sample delivery point 41, chip sample delivery point 42, core respectively
Piece testing site 44 enters, and flows through chip stream sample channel 43, reaches 44 hybrid reaction of Array analysis point.
By Fig. 2,3,4 it is found that micro-fluidic chip 45 is the chip with single testing site 26, test solution carries out at testing site 26
It is photometric detection reception pipe 5, luminosity that hybrid reaction, which in the surface of testing site 26 is photometric detection light-emitting tube 18, underface,
It detects the co-ordination of both light-emitting tube 18 and photometric detection reception pipe 5 and realizes photometric detection.
Referring to Fig. 5, the glass objective table 14 inside shell 46, the bottom before and after left end and right end is respectively mounted pulley 63,
The pulley 63 of 14 left end of glass objective table coordinates with left slideway 9, and pulley 63 and the right slideway 10 of 1 right end of glass objective table coordinate,
Keep glass objective table 14 front and back free to slide on left slideway 9 and right slideway 10 by pulley 63, sliding push-pull glass objective table
14, towards multi-form, single testing site, meanwhile, facilitate the replacement of micro-fluidic chip 45.
Referring to Fig. 6, fixed there are two round small slot 62 in the ceiling center of 46 upper chamber of shell, to fixed luminosity inspection
Light-emitting tube 18 is surveyed, two pins of photometric detection light-emitting tube 18 are inserted in the small slot of two circles 62, realizes difference
The convertibility of wavelength luminous tube.The centre bit of photometric detection light-emitting tube 18, testing site 26 and photometric detection reception pipe 5 one
On vertical line, meet utmostly absorption of the photometric detection reception pipe 5 to transmitting light in photometric detection.Temperature sensor 61 is placed on
On the edge of glass objective table 14, for detecting micro-fluidic chip local environment temperature in real time.
Referring to Fig. 7 and Fig. 8, it is additionally provided with heating plate 52 inside 46 upper chamber of shell and four pieces are erected with interval from front to back
The partition board for the rectangle directly arranged, the size and thickness all same of four pieces of partition boards, four pieces of partition boards are first partition respectively from front to back
48, second partition 49, third partition board 50 and the 4th partition board 51, first partition 48 and second partition 49 are located at photometric detection light emitting
The front of pipe 18, second partition 49 and third partition board 50 are located at the rear of photometric detection light-emitting tube 18, i.e. photometric detection light is sent out
Pipe 18 is penetrated between second partition 49 and third partition board 50.The left end of every piece of partition board is all close with the left plate of 46 upper chamber of shell
Envelope is fixedly connected, and the right plate of the right end of every piece of partition board all with 46 upper chamber of shell is sealedly and fixedly connected.Wherein, first partition 48
It is closely coupled with the top plate of 46 upper chamber of shell with the top of third partition board 50, and bottom between upper chamber bottom surface there are
Gap has certain gap apart from glass objective table 14, about stays the vertical range of 5cm.Second partition 49 and the 4th partition board 51
Certain vertical range is arranged with glass objective table 14 at bottom, about stays the gap of 3cm, the top of second partition 49 and the 4th partition board 51
There are the gaps 5cm between the top plate of 46 upper chamber of shell in portion, and four pieces of partition boards is made to be staggeredly placed up and down along the longitudinal direction.Fan
22 are located at the upper front part of first partition 48, are fixed on 46 upper chamber's top plate of shell.According to the straightline propagation principle of light, because of four
Block partition board is staggeredly placed, and the shielding to ambient light may be implemented, and dark room conditions are provided for photometric detection experiment.Heating plate 52 is set
It between first partition 48 and second partition 49, is fixed in first partition 48, can be heated to flowing through air-flow, to arrive
Up to the purpose of Control experiment environment temperature.Arrow in Fig. 8 represents the flow direction of wind, is passed through extraneous air-flow by fan 22
It is blown by 48 bottom gap of first partition, when by heating plate 52, air-flow is heated, using the top clearance of second partition 49
Into at the micro-fluidic chip 45 of 46 upper chamber of shell, by the bottom gap of third partition board 50 and the top clearance of the 4th partition board 51
Discharge.When air-flow passes through heating plate 52, the heating temperature range of control heating plate 52 is the effect that can reach control gas flow temperature
Fruit achievees the purpose that control 45 local environment temperature of micro-fluidic chip within a certain error range to meet.
Referring to Fig. 9 and Figure 10, the lower chambers of the shell 46 of each independent submodule be internally provided with voltage transformation module 53,
Photometric detection optical receiver module 54, photometric detection optical transmitter module 55, main control chip module 57, touch screen display control module 58
With fan and heating plate control module 60 this six modules, in addition to voltage transformation module 53 and main control chip module 57, remaining
Photometric detection optical receiver module 54, photometric detection optical transmitter module 55, touch screen display control module 58 and fan and heating plate
Control module 60 is integrated on a control module circuit board 59.
It is internally provided with 64 He of master controller in the lower chambers of the shell 46 of wherein any one submodule of multiple submodule
There are one selection circuit modules 65, i.e. master controller 64 and selection circuit module 65 each, may be mounted at any one submodule
In block.The input terminal of the output end connection selection circuit module 65 of master controller 64, the output end difference of selection circuit module 65
The input terminal of each main control chip module 57 is connected, master controller 64 reaches control main control chip mould by selection circuit module 65
Function whether block 57 works.Main control chip module 57 is separately connected by different ports belongs to the same submodule with it
Photometric detection optical receiver module 54, photometric detection optical transmitter module 55, temperature sensor 61,58 and of touch screen display control module
Fan and heating plate control module 60.It is each that external voltage by voltage conversion chip is converted to remaining by voltage transformation module 53
Voltage needed for module, to control the normal work of modules.
Referring to Figure 10, the control structure inside one of independent sub-modules is illustrated only in Figure 10.Master controller 64 to
Selection circuit module 65 sends control signal, the selection port of selection circuit module 65 respectively with the main control chip in each unit
Module 57 is connected, and sends selection signal to main control chip module 57, each unit main control chip module 57 is determined by selection signal
Working condition：It starts to work, be stopped.If main control chip module 57 is in stop working state, which will not work
Make；If main control chip module 57 is in start-up operation state, which starts to work normally.Main control chip module 57 is by each
Port respectively with touch screen display control module 58, photometric detection optical transmitter module 55, photometric detection optical receiver module 54, temperature
Sensor 61 is connected with fan and heating plate control module 60.Main control chip module 57 is sent out to photometric detection optical transmitter module 55
Control signal is sent, the working condition of the control signal deciding photometric detection optical transmitter module 55.Photometric detection optical transmitter module 55
It is connected with photometric detection light-emitting tube 18 by port, and is sent to control signal for controlling photometric detection light-emitting tube
18 light on and off and bright dark degree.Master control chip module 57 sends control signal to photometric detection optical receiver module 54, is used for
Determine the working condition of optical receiver module 54；Meanwhile photometric detection optical receiver module 54 passes through port and photometric detection reception pipe 5
It is connected, the analog data that photometric detection light receiving tube 5 collects will be sent back to photometric detection light-receiving mould by port
Block 54 is then forwarded to main control chip module 57, by main control chip after photometric detection optical receiver module 54 is processed into digital quantity
Module 57 stores and is sent to touch screen display control module 58, and touch screen display control module 58 will pass through end after data processing
Mouth is sent to the display of touch screen 1.Main control chip module 57 receives temperature sensor 61 by port and collects micro-fluidic chip
The temperature data of local environment, is sent to touch screen display control module 58 after storage, touch screen display control module 58 will be warm
Touch screen 1 is sent to after degrees of data processing by port to show.Main control chip module 57 is to fan and heating plate control module 60
Send control signal, the working condition for determining fan and heating plate control module 60.Fan and heating plate control module 60
It is connected with fan 22 and heating plate 52 by port, and is sent to control signal and is used to control the switch of fan and turns
Speed, the temperature of heating plate.
When working the present invention is based on the multiple-unit integration test device of micro-fluidic chip photometric detection, pass through left slideway first
9 and right slideway 10 by glass objective table 14 slide pull out, then place the micro-fluidic chip 45 of sample introduction, and make glass loading
Alignment mark point on platform 14 is overlapped with the testing site 26 of micro-fluidic chip 45.Glass is carried by left slideway 9 and right slideway 10
Object platform 14 slides in pushing in device.
After opening power supply, the alternating voltage of 220V is converted to the required voltage of modules by voltage transformation module 53.
Selection signal is sent to selection circuit module 64 by master controller 65, it is made to select each submodule main control chip module 57 in the block
It works, non-selected submodule main control chip module 57 in the block will be in off position.For the submodule of selection,
In temperature sensor 61 environment temperature detected is inputted into main control chip module 57, main control chip module 57 is by the ring of detection
Border temperature is compared with preset normal temperature range, if necessary to adjust temperature, is then controlled through each fan and heating plate
Module 60 controls corresponding fan 22 and heating plate 52 works, and realizes that temperature is adjusted.Then, main control chip module 57 is sent first
Signal is controlled, allows photometric detection optical receiver module 54, photometric detection optical transmitter module 55, touch screen display control module 58 and temperature
Degree sensor 61 is in start-up operation state.Wherein, photometric detection optical receiver module 54 is opened with photometric detection optical transmitter module 55
Beginning cooperating is controlled the bright dark degree of photometric detection light-emitting tube 18, photometric detection light by photometric detection optical receiver module 54
Its collected photometric detection optical signal of institute, analog signals are changed by reception pipe 5 by photometric detection optical receiver module 54
After digital signal, it is sent to the storage of main control chip module 57, then touch screen display control mould is sent to by main control chip module 57
Block 58 shows 1 display data of touch screen by control.Meanwhile temperature sensor 61 detects current micro-fluidic chip local environment in real time
Temperature, and the temperature signal of digital quantity is fed back into main control chip module 57, main control chip module 57 is not only sent it to
Touch screen display control module 58 shows 1 display data of touch screen by control, it is also worth phase up and down with initially set temperature
Compare.If not within the temperature range of setting, main control chip module 57 sends control letter to fan and heating plate control module 60
Number, it is at start-up operation state, fan and heating plate control module 60 and is sent to fan 22 and heating plate 52 by port
Control signal, intake, the intake velocity of temperature and fan 22 for controlling current heating plate 52；If in the temperature of setting
In range, fan and heating plate control module 60 do not need work.During experiment, intelligence is completed certainly inside entire experimental provision
Dynamic control, autonomous detection and Real-time Feedback；Meanwhile whole process cycle carries out, until off-test.Finally, entire experiment
Device carries out photometric detection for micro-fluidic chip 45 and provides intellectualized operation and good experimental enviroment.
Claims (9)
1. a kind of multiple-unit integration test device based on micro-fluidic chip photometric detection, it is characterized in that：With multiple independent
Submodule, from left to right "-" type arranges that the outside of each submodule is shell to multiple submodule（46）, each submodule it is outer
Shell（46）Inside is separated into upper and lower two chambers by one piece of diaphragm plate, and photometric detection reception pipe is fixed on the bottom plate of upper chamber
（5）, be fixed with positioned at photometric detection reception pipe on top plate（5）The photometric detection light-emitting tube of surface（18）, detect light emitting
Pipe（18）With photometric detection reception pipe（5）Between be horizontal glass objective table（14）, glass objective table（14）It is set on upper surface
Put micro-fluidic chip（45）, glass objective table（14）Left end passes through left slideway（9）Connected with outer casing（46）Left plate, right end passes through
Right slideway（10）Connected with outer casing（46）Right plate, glass objective table（14）Edge on be placed with temperature sensor（61）,
Shell（46）Upper chamber is internally provided with heating plate（52）The first partition for the rectangle arranged vertically with interval from front to back
（48）, second partition（49）, third partition board（50）With the 4th partition board（51）, first partition（48）And second partition（49）Positioned at light
Degree detection light-emitting tube（18）Front, second partition（49）With third partition board（50）Positioned at photometric detection light-emitting tube（18）'s
Rear, the left end of every piece of partition board all with shell（46）The left plate of upper chamber is sealedly and fixedly connected, the right end of every piece of partition board all with
Shell（46）The right plate of upper chamber is sealedly and fixedly connected；First partition（48 ）With third partition board（50）Top and shell
（46）The top plate of upper chamber is closely coupled, bottom with there are gaps between upper chamber bottom surface；Second partition（49）With the 4th every
Plate（51）Bottom with glass objective table（14）There are gap, top and shell（46）Between the top plate of upper chamber there are
Gap, fan（22）Positioned at first partition（48）Upper front part and be fixed on shell（46）On upper chamber's top plate；Each shell
（46）Lower chambers be internally provided with photometric detection optical receiver module（54）, photometric detection optical transmitter module（55）, main control chip mould
Block（57）With fan and heating plate control module（60）, the shell of any one submodule wherein（ 46）Lower chambers inside
Equipped with master controller（64）With selection circuit module（65）, master controller（64）Output end connects selection circuit module（65）Input
End, selection circuit module（65）Output end is separately connected each main control chip module（57）Input terminal；Each main control chip mould
Block（57）The photometric detection optical receiver module for belonging to the same submodule is separately connected by different ports（54）, photometric detection
Optical transmitter module（55）, temperature sensor（61）With fan and heating plate control module（60）.
2. the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 1, it is characterized in that：It is more
A submodule from left to right arrange by "-" type, the shell of adjacent two submodules（46）Between share a side plate.
3. the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 1, it is characterized in that：Outside
Shell（46）Lower chambers front side board on be equipped with touch screen（1）, shell（46）Lower chambers be internally provided with touch screen display control
Module（58）, touch screen（1）Through touch screen display control module（58）Connect corresponding main control chip module（57）.
4. the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 1, it is characterized in that：Outside
Shell（46）Lower chambers front side board on be equipped with touch screen（1）, shell（46）Lower chambers be internally provided with touch screen display control
Module（58）, touch screen（1）Through touch screen display control module（58）Connect corresponding main control chip module（57）.
5. the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 1, it is characterized in that：Glass
Glass objective table（14）Left end and right end before and after bottom be respectively arranged with pulley（63）, glass objective table（14）The pulley of left end（63）
With left slideway（9）Cooperation, glass objective table（1）The pulley of right end（63）With right slideway（10）Cooperation.
6. the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 1, it is characterized in that：It is micro-
Fluidic chip（45）There are one testing sites for upper tool（26）, testing site（26）With photometric detection light-emitting tube（18）, photometric detection connects
Closed tube（5）Upper and lower face.
7. a kind of experiment side of the multiple-unit integration test device based on micro-fluidic chip photometric detection as described in claim 1
Method, it is characterized in that including the following steps：
A, pass through left slideway（9）With right slideway（10）By glass objective table（14）Sliding pulls out, and places the micro-fluidic of sample introduction
Chip（45）, pass through left slideway（9）With right slideway（10）By glass objective table（14）Sliding push-in；
B, master controller（64）To selection circuit module（65）Signal is sent, each unit main control chip module is selected（57）Beginning
Or the working condition stopped；
C, by the unit main control chip module of selection work（57）Control signal is sent by photometric detection optical receiver module（54）, light
Degree detection optical transmitter module（55）And temperature sensor（61）It starts to work, photometric detection optical receiver module（54）Control luminosity inspection
Survey light-emitting tube（18）Bright dark degree, photometric detection light receiving tube（5）By its institute, collected signal passes through photometric detection light
Receiving module（54）It is sent to main control chip module（57）, temperature sensor（61）Current micro-fluidic chip is detected in real time（45）Institute
Locate the temperature of environment and feeds back to main control chip module（57）.
8. the test method of the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 7,
It is characterized in that：By the unit main control chip module of selection work（57）In the submodule at place, temperature sensor（61）By institute
The environment temperature of detection inputs main control chip module（57）, main control chip module（57）By the environment temperature of detection with preset
Normal temperature range comparison, if necessary to adjust temperature, then through fan and heating plate control module（60）Control corresponding wind
Fan（22）And heating plate（52）Work realizes that temperature is adjusted.
9. the test method of the multiple-unit integration test device based on micro-fluidic chip photometric detection according to claim 7,
It is characterized in that：Photometric detection light receiving tube（5）By its institute, collected signal passes through photometric detection optical receiver module（54）It sends
To main control chip module（57）Afterwards, then by main control chip module（57）It is sent to touch screen display control module（58）, by controlling
Show touch screen（1）Display.
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| CN110763641B (en) * | 2019-11-29 | 2024-04-09 | 京东方科技集团股份有限公司 | Detection device and detection method |
| CN114295961B (en) * | 2021-12-30 | 2024-01-16 | 上海季丰电子股份有限公司 | Power temperature cycle test method and device for high-power chip and electronic equipment |
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