CN102861379A - Icterus neonatorum therapeutic system - Google Patents

Icterus neonatorum therapeutic system Download PDF

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Publication number
CN102861379A
CN102861379A CN2012103212864A CN201210321286A CN102861379A CN 102861379 A CN102861379 A CN 102861379A CN 2012103212864 A CN2012103212864 A CN 2012103212864A CN 201210321286 A CN201210321286 A CN 201210321286A CN 102861379 A CN102861379 A CN 102861379A
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light source
blue
irradiation
neonatal jaundice
unit
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CN102861379B (en
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江卫强
刘建
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BEIJING TIANZHU JIYE TECHNOLOGY DEVELOPMENT CO LTD
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BEIJING TIANZHU JIYE TECHNOLOGY DEVELOPMENT CO LTD
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Abstract

The invention relates to an icterus neonatorum therapeutic system, which comprises a radiation blue light source array, an auxiliary white light source, an image collection device, a data analysis and processing unit and a light control unit. According to the icterus neonatorum therapeutic system, icterus index changes of all parts of a neonatorum body can be dynamically detected, and control signals are output to the light control unit in time according to detection results, and moreover, radiation light sources for therapy are accurately controlled, and thereby, radiation light signals can be adjusted in time according to the detection results, and an effect of light therapy is obviously improved. Moreover, the icterus neonatorum therapeutic system is safer and more effective, and hurt caused to neonatorum because of excessive therapy is avoided.

Description

The Neonatal jaundice therapy system
Technical field
The present invention relates to a kind of medical apparatus and instruments, more specifically, the present invention relates to a kind of Neonatal jaundice therapy system in conjunction with digital camera technology and image recognition technology.
Background technology
Bilirubin accumulates to make in skin, mucosa, sclera and some body fluid in blood, tissue and interstitial fluid and xanthochromia occurs, is referred to as clinically jaundice.Neonatal jaundice is neonatal common disease, and as a rule neonatal jaundice can be divided into physiological and pathologic.On physiological, physiologic jaundice refers to that neonatal serum total bilirubin content does not exceed the scope of a permission, can disappear in the short time voluntarily after birth.To surpassing physiological institute allowed band, then be called pathological jaundice.At neonatal period, neonatal blood brain barrier causes jaundice, to neonate brain injury, has a strong impact on its intelligence development, even may cause neonatal death.
At present, Neonatal jaundice therapy mainly adopts the method for blue light illumination to carry out.Namely utilize the blue light with some strength that the body skin of neonate except eyes and genitals shone.Therapeutic instrument for neonatal jaundice mainly contains following several in the prior art:
1, blue light box: mainly comprise power supply, temperature controller, heater, irradiation blue-light source, transparent or opaque cabinet shell.The neonate that to put on cover glass and pudendum protecting cover during use is put in the casing, and the neonate health that exposes is shone; Belong to closed irradiation treatment equipment.For example the disclosed cabin of CN202105327U formula ohmeda biliblanket phototherapy just belongs to box sealing irradiation treatment equipment.
2, blue light bed: mainly comprise power supply, irradiation blue-light source, bed body etc.The neonate that to put on cover glass and pudendum protecting cover during use is placed on above the bed body that can see through irradiation light, the exposed irradiation treatment that carries out in back.The Infant with Jaundice therapeutic bed of the disclosed control able to programme of CN102327671A for example.The blue light bed belongs to open therapeutic equipment, also exists the single face therapeutic efficiency low except existing to personnel on every side are influential, the shortcoming that treatment time is grown.
3, blue light blanket: mainly comprise power supply, irradiation blue-light source, output optical fibre, optical fiber blanket etc.The neonate that to put on cover glass and pudendum protecting cover during use is placed on the optical fiber blanket in bed of shop, the exposed irradiation treatment that carries out in back.For example, CN102327672A discloses a kind of blue light treatment blanket for infant jaundice.Blue light blanket belongs to open therapeutic equipment, blue light to personnel on every side without injury, but exist therapeutic efficiency low, the shortcoming that treatment time is long.
Also there is following defective in ohmeda biliblanket phototherapy of the prior art: the zone of (1) blue light illumination can only manually set in advance definite usually, is difficult in time adjust; (2) intensity of blue light illumination and time can only manually set in advance definite: studies show that, bilirubinic drop-out value hourly and rate of descent have direct relation in the intensity of blue light illumination and the infant blood.The phototherapy effect increases with the increase of light intensity, uses the high strength phototherapy can avoid invalid phototherapy and minimizing phototherapy time.And existing therapeutic instrument is difficult to usually according to the degree of infant jaundice and the setting that the blue light illumination parameter of optimization that can be for reference is provided for medical personnel according to the regional different of irradiation; (3) effect for irradiation is difficult in time carry out quantitative measurement and evaluation; Neonate can change along with the variation of blood mesobilirubin from the color of birth beginning health, experimental results show that there are certain corresponding relation in bilirubin in the blood and the color of infant skin.For the evaluation of the phototherapy effect of infant, the most frequently used way of taking at present is at pre-irradiation or after irradiation a period of time, utilizes the equipment-Percutaneous Jaundice Instrumentation of optics colorimetric detection to carry out the measurement of icteric index by medical personnel, to estimate radiation response.
Summary of the invention
The above-mentioned technical problem that exists in order to solve prior art the object of the present invention is to provide a kind of therapeutic instrument for neonatal jaundice.Therapeutic instrument for neonatal jaundice of the present invention comprises jaundice detecting unit and illumination control unit, icteric index that can detection of dynamic neonate health each several part change and in time according to testing result output control signal to the illumination control unit, thereby can in time adjust the irradiation optical signal according to testing result, improve the effect of light treatment, and safety and effectively more, avoid because of over-treatment cause to neonatal injury.
To achieve these goals, the invention provides following technical scheme:
A kind of Neonatal jaundice therapy system comprises: irradiation blue-light source array, auxiliary white light source, image collecting device, data analysis and processing unit and illumination control unit; Wherein, irradiation blue-light source array is comprised of m * n adjustable independent blue light unit of intensity, and the blue light that provides Icterus treatment to use is provided; Auxiliary white light source is used for providing image acquisition required auxiliary white light; Image collecting device, for closing at irradiation blue-light source array and assisting under the condition of white light source unlatching, gather M * N the rectangle graticule picture that the newborn skin folded light beam forms image and obtains the neonate body part, and the skin color of the corresponding corresponding position of the color of each graticule picture; Data analysis and processing unit utilize the corresponding relation of color and icteric index to calculate the icteric index that detection obtains the corresponding body part of each grid, and the output control signal are to the illumination control units; The illumination control unit is by the control signal control irradiation blue-light source array of data analysis and processing unit input and the opening and closing of auxiliary white light source, and the exposure rate of each independent blue light unit in the blue-light source array is penetrated in adjusting; And m>=M>=2, n>=N>=2.
Wherein, described Neonatal jaundice therapy system also comprises input and output unit; Described input block is used for inputting initial exposure rate and human assistance control signal; Described output unit is used for output digital image and supplemental characteristic.
Wherein, described image collecting device is preferably the colorful digital video camera.
Wherein, described blue light unit is the blue-ray LED light source.
Wherein, described auxiliary white light source is comprised of a plurality of independent white LED light sources.
Wherein, m>=M>=5, n>=N>=5.
Wherein, output unit is LED display or LCDs.
Compared with prior art, Neonatal jaundice therapy of the present invention system has following beneficial effect: therapeutic instrument for neonatal jaundice of the present invention is by arranging image collecting device, data analysis and processing unit and illumination control unit, adopted in addition the treatment that is made of a plurality of independent blue light sources with irradiation blue-light source array; Thereby the icteric index that can realize detection of dynamic neonate health each several part changes and in time exports control signal to the illumination control unit according to testing result, and to the treatment accurately control with radiation source, thereby can in time adjust the irradiation optical signal according to testing result, improve significantly the effect of light treatment, and safety and effectively more, avoid because of over-treatment cause to neonatal injury.
Description of drawings
Fig. 1 is the structural representation of the described Neonatal jaundice therapy of embodiment 1 system;
Fig. 2 is that M * N rectangle graticule of the neonate body part that gathers of image collecting device is as schematic diagram;
Fig. 3 is the change curve of newborn skin surface icteric index with treatment time.
The specific embodiment
Below with reference to the specific embodiment Neonatal jaundice therapy of the present invention system is explained in detail.
Embodiment 1
As shown in Figure 1, the Neonatal jaundice therapy system of the present embodiment comprises: irradiation blue-light source array 10, auxiliary white light source 20, image collecting device 30, therapeutic bed 70, data analysis and processing unit 40, illumination control unit 50 and input and output unit 60; Wherein, irradiation blue-light source array 10 is comprised of m * n adjustable independent blue light unit of intensity, and the blue light that provides Icterus treatment to use is provided; Auxiliary white light source 20 is used for providing image acquisition required auxiliary white light; Image collecting device 30, for closing at irradiation blue-light source array and assisting under the condition of white light source unlatching, the image that collection newborn skin folded light beam forms and M * N the rectangle graticule picture that obtains neonate body part as shown in Figure 2, and the skin color of the corresponding corresponding position of the color of each graticule picture; Data analysis and processing unit 40, utilize the corresponding relation of color and icteric index to calculate the icteric index that detection obtains the corresponding body part of each grid, described data analysis and processing unit can be microprocessors, it by algorithm (for example: the algorithm of the color that obtains according to irradiation and the establishment of the corresponding relation of icteric index) calculate the icteric index each net region in, and export control signal to the illumination control unit; Illumination control unit 50 is by the control signal control irradiation blue-light source array of data analysis and processing unit input and the opening and closing of auxiliary white light source, then according to such as the change curve of the exemplary icteric index of Fig. 3 with treatment time, the icteric index curvature of a curve of time to time change changes different and different with light intensity, high irradiation light intensity causes that icteric index reduces faster, (P1<P2 among the figure, Px represents the light intensity of shining), by regulating the exposure rate of irradiation blue light unit, can realize the therapeutic effect that reduces more expeditiously icteric index of optimizing.For reaching preferably phototherapy effect, according to Shannon's sampling theorem, require m>=2M>=10n>=2N>=10; Have the identical length of side with each grid in M * N rectangle grid corresponding to neonate body part, and its length of side is less than or equal to the length of side (for example: the length of side that can set minimum irradiation skin is 2CM) of the minimum skin grid that shines when phototherapy.
Therapy system in use, under the condition of closing the auxiliary white light source illumination of irradiation blue-light source array unlatching, at first utilize the image collecting device that is installed in auxiliary white light source homonymy to take and gather the image of newborn infant, and calculate the yellow distribution situation at each position of infant health, the algorithm relation of setting up according to color and icteric index obtains the icteric index in each rectangle grid, and when infant is shone the blue light strength of different irradiation areas is carried out initial automatic setting or revise the initial value of exposure rate parameter for medical personnel by input block.
After infant has been carried out the blue light illumination of the scheduled time, system stops blue light illumination the short time and opens auxiliary white light, take the image of infant health, calculate the yellow chrominance distribution situation at each position of infant health, the distribution situation of the yellow of each distributed areas of health that the relevant parameter of this distribution situation is obtained during in conjunction with the irradiation beginning, can calculate within the time of determining, because irradiation and to the actual effect that the change (jaundice index) of the yellow of the zones of different of infant health causes, mainly be the speed that the absolute value that changes of colourity and colourity change; Based on this intensity of the irradiation blue light of irradiation infant zones of different is adjusted automatically, the perhaps subregional irradiation of stop realizes optimized exposure rate; Repeatedly carry out above-mentioned adjustment finishing whole treatment step, thereby can improve phototherapy effect and efficient.
The above; it only is preferred implementation of the present invention; can not be interpreted as limiting protection scope of the present invention with this, the embodiment of all distortion that is equal to of making in the claimed scope of claims of the present invention and change is all in the present invention's scope required for protection.

Claims (7)

1. a Neonatal jaundice therapy system comprises: irradiation blue-light source array, auxiliary white light source, image collecting device, data analysis and processing unit and illumination control unit; It is characterized in that: irradiation blue-light source array is comprised of m * n adjustable independent blue light unit of intensity, and the blue light that provides Icterus treatment to use is provided; Auxiliary white light source is used for providing image acquisition required auxiliary white light; Image collecting device, for closing at irradiation blue-light source array and assisting under the condition of white light source unlatching, gather M * N the rectangle graticule picture that the newborn skin folded light beam forms image and obtains the neonate body part, and the skin color of the corresponding corresponding position of the color of each graticule picture; Data analysis and processing unit utilize the corresponding relation of color and icteric index to calculate the icteric index that detection obtains the corresponding body part of each grid, and the output control signal are to the illumination control units; The illumination control unit is by the control signal control irradiation blue-light source array of data analysis and processing unit input and the opening and closing of auxiliary white light source, and the exposure rate of each independent blue light unit in the blue-light source array is shone in adjusting; And m>=M>=2, n>=N>=2.
2. Neonatal jaundice therapy claimed in claim 1 system is characterized in that: described Neonatal jaundice therapy system also comprises input and output unit; Described input block is used for inputting initial exposure rate and human assistance control signal; Described output unit is used for output digital image and supplemental characteristic.
3. Neonatal jaundice therapy claimed in claim 1 system, it is characterized in that: described image collecting device is preferably the colorful digital video camera.
4. Neonatal jaundice therapy claimed in claim 1 system, it is characterized in that: described blue light unit is the blue-ray LED light source.
5. Neonatal jaundice therapy claimed in claim 1 system, it is characterized in that: described auxiliary white light source is comprised of a plurality of independent white LED light sources.
6. Neonatal jaundice therapy claimed in claim 1 system is characterized in that: m>=M>=5, n>=N>=5.
7. Neonatal jaundice therapy claimed in claim 1 system, it is characterized in that: output unit is LED display or LCDs.
CN201210321286.4A 2012-09-04 2012-09-04 Icterus neonatorum therapeutic system Active CN102861379B (en)

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Cited By (15)

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Publication number Priority date Publication date Assignee Title
CN104759034A (en) * 2014-11-05 2015-07-08 香港纺织及成衣研发中心有限公司 Phototherapy weaving blanket
CN105427722A (en) * 2015-12-09 2016-03-23 天津市医学堂科技有限公司 Jaundice teaching model
CN105473060A (en) * 2013-08-06 2016-04-06 皇家飞利浦有限公司 System and method for extracting physiological information from remotely detected electromagnetic radiation
CN105664372A (en) * 2016-02-24 2016-06-15 广州美琳美健医疗科技有限公司 Blue-light therapeutic instrument for jaundice detection
CN106039579A (en) * 2016-05-12 2016-10-26 京东方科技集团股份有限公司 Illumination medical device and method using same
CN107115593A (en) * 2017-05-13 2017-09-01 盈泰(苏州)医疗科技有限公司 A kind of therapeutic instrument for neonatal jaundice
CN107249686A (en) * 2014-11-21 2017-10-13 尤瓦拉生物科技(控股)有限公司 The treatment system engineered for percutaneous in-vivo tissue
CN108078544A (en) * 2017-12-28 2018-05-29 中国人民解放军成都军区总医院 Jaundice measurement device of being grown up and its detection method
CN110368603A (en) * 2019-09-04 2019-10-25 河南科技大学第一附属医院 It is a kind of for treating the light source adjustable therapeutic device of icterus neonatorum
CN110368602A (en) * 2019-09-04 2019-10-25 河南科技大学第一附属医院 A kind of multiple light courcess infant jaundice light exposure treatment equipment
CN110730334A (en) * 2019-10-25 2020-01-24 合肥威康医疗器械有限公司 Video monitoring system and method for filtering blue light
CN112402809A (en) * 2020-11-23 2021-02-26 于蛟 Clinical paediatrics jaundice treatment device of using
CN112826449A (en) * 2021-01-04 2021-05-25 北京变色龙科技有限公司 Jaundice triage information analysis method and system based on automatic identification
WO2021244253A1 (en) * 2020-06-04 2021-12-09 京东方科技集团股份有限公司 Jaundice diagnosis and treatment system and computer-readable storage medium
CN113975643A (en) * 2021-10-21 2022-01-28 杭州英诺维科技有限公司 Blue light box on-line monitoring method and blue light box on-line monitoring system

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CN101703390A (en) * 2009-11-24 2010-05-12 河北科技大学 System for intelligently detecting and treating infantile jaundice
CN201668377U (en) * 2010-06-11 2010-12-15 郝天羽 Household monitoring system for jaundice of newborn
CN102327671A (en) * 2011-09-22 2012-01-25 昆山一恒仪器有限公司 Programmed controllable infant jaundice treatment bed

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US20080008370A1 (en) * 2006-06-20 2008-01-10 Shiu-Shin Chio Method and apparatus for diagnosing conditions using tissue color
CN101703390A (en) * 2009-11-24 2010-05-12 河北科技大学 System for intelligently detecting and treating infantile jaundice
CN201668377U (en) * 2010-06-11 2010-12-15 郝天羽 Household monitoring system for jaundice of newborn
CN102327671A (en) * 2011-09-22 2012-01-25 昆山一恒仪器有限公司 Programmed controllable infant jaundice treatment bed

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10575764B2 (en) 2013-07-08 2020-03-03 Koninklijke Philips N.V. System and method for extracting physiological information from remotely detected electromagnetic radiation
CN105473060A (en) * 2013-08-06 2016-04-06 皇家飞利浦有限公司 System and method for extracting physiological information from remotely detected electromagnetic radiation
CN104759034A (en) * 2014-11-05 2015-07-08 香港纺织及成衣研发中心有限公司 Phototherapy weaving blanket
CN107249686A (en) * 2014-11-21 2017-10-13 尤瓦拉生物科技(控股)有限公司 The treatment system engineered for percutaneous in-vivo tissue
CN105427722A (en) * 2015-12-09 2016-03-23 天津市医学堂科技有限公司 Jaundice teaching model
CN105664372A (en) * 2016-02-24 2016-06-15 广州美琳美健医疗科技有限公司 Blue-light therapeutic instrument for jaundice detection
CN105664372B (en) * 2016-02-24 2018-06-19 广州美琳美健医疗科技有限公司 Jaundice detects blue-light treatment instrument
CN106039579A (en) * 2016-05-12 2016-10-26 京东方科技集团股份有限公司 Illumination medical device and method using same
US10940328B2 (en) 2016-05-12 2021-03-09 Boe Technology Group Co., Ltd. Irradiation device and method for using the same
CN107115593A (en) * 2017-05-13 2017-09-01 盈泰(苏州)医疗科技有限公司 A kind of therapeutic instrument for neonatal jaundice
CN108078544A (en) * 2017-12-28 2018-05-29 中国人民解放军成都军区总医院 Jaundice measurement device of being grown up and its detection method
CN110368602A (en) * 2019-09-04 2019-10-25 河南科技大学第一附属医院 A kind of multiple light courcess infant jaundice light exposure treatment equipment
CN110368603A (en) * 2019-09-04 2019-10-25 河南科技大学第一附属医院 It is a kind of for treating the light source adjustable therapeutic device of icterus neonatorum
CN110368602B (en) * 2019-09-04 2021-01-15 河南科技大学第一附属医院 Infant jaundice phototherapy equipment with multiple light sources
CN110368603B (en) * 2019-09-04 2021-03-16 河南科技大学第一附属医院 Light source adjustable treatment device for treating neonatal jaundice
CN110730334A (en) * 2019-10-25 2020-01-24 合肥威康医疗器械有限公司 Video monitoring system and method for filtering blue light
WO2021244253A1 (en) * 2020-06-04 2021-12-09 京东方科技集团股份有限公司 Jaundice diagnosis and treatment system and computer-readable storage medium
CN112402809A (en) * 2020-11-23 2021-02-26 于蛟 Clinical paediatrics jaundice treatment device of using
CN112826449A (en) * 2021-01-04 2021-05-25 北京变色龙科技有限公司 Jaundice triage information analysis method and system based on automatic identification
CN112826449B (en) * 2021-01-04 2023-01-24 北京变色龙科技有限公司 Jaundice triage information analysis method and system based on automatic identification
CN113975643A (en) * 2021-10-21 2022-01-28 杭州英诺维科技有限公司 Blue light box on-line monitoring method and blue light box on-line monitoring system
CN113975643B (en) * 2021-10-21 2024-04-16 杭州英诺维科技有限公司 Online monitoring method and online monitoring system for blue light box

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