CN105664372A - Blue-light therapeutic instrument for jaundice detection - Google Patents

Blue-light therapeutic instrument for jaundice detection Download PDF

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Publication number
CN105664372A
CN105664372A CN201610102779.7A CN201610102779A CN105664372A CN 105664372 A CN105664372 A CN 105664372A CN 201610102779 A CN201610102779 A CN 201610102779A CN 105664372 A CN105664372 A CN 105664372A
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light source
blue
led light
jaundice
light
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CN105664372B (en
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肖云生
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Guangzhou Vigorous And Graceful Medical Science And Technology Co Ltd Of Us Beautiful Jade
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Guangzhou Vigorous And Graceful Medical Science And Technology Co Ltd Of Us Beautiful Jade
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/0621Hyperbilirubinemia, jaundice treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0064Body surface scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441Skin evaluation, e.g. for skin disorder diagnosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2503/00Evaluating a particular growth phase or type of persons or animals
    • A61B2503/04Babies, e.g. for SIDS detection
    • A61B2503/045Newborns, e.g. premature baby monitoring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/065Light sources therefor
    • A61N2005/0651Diodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0658Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662Visible light
    • A61N2005/0663Coloured light

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Dermatology (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

The invention relates to a blue-light therapeutic instrument for jaundice detection. The blue-light therapeutic instrument is composed of a blue-light LED light source, a control module, a power supply module, a shell, a spotlight head, a coaxial optical fiber and a jaundice index detection unit. The blue-light LED light source is used as a treatment light source; a detection-light LED light source is used as a detection light source; and light guiding is carried out by using the coaxial optical fiber. Therefore, the blue-light therapeutic instrument not only has a jaundice treatment function but also has a jaundice index detection function; and the jaundice treatment power can be adjusted according to a jaundice index detection result. The side effect can be reduced substantially; the power is enhanced; the treatment time is shortened substantially; various side effects and instability of the traditional phototherapy instrument are eliminated. The severe jaundice disease of the newborn can be treated effectively.

Description

Jaundice detection blue-light treatment instrument
Technical field
The present invention relates to medical instruments field, detect blue-light treatment instrument in particular to jaundice.
Background technology
Bilirubin accumulates in blood, tissue and interstitial fluid and makes xanthochromia occur in skin, mucosa, sclera and some body fluid, is referred to as jaundice clinically. Neonatal jaundice is neonatal common disease. At present, hospital generally adopts percutaneous to survey subcutaneous ulcer instrument and blood test liver function test serum total bilirubin value, thus judges jaundice degree. Neonatal jaundice therapy mainly adopts the method for blue light illumination to carry out, and namely utilizes and has the blue light of some strength neonate body skin except eyes and genitals is irradiated.
The detection of jaundice generally adopts percutaneous to survey subcutaneous ulcer instrument and blood test liver function test serum total bilirubin value, and blood test liver function is the traditional method that jaundice checks, but taking a blood sample is invasive inspection, neonate can be caused pain; Although it is noninvasive test method that common percutaneous surveys subcutaneous ulcer instrument, and check that speed is fast, but not there is the function for the treatment of.
Therapeutic instrument for neonatal jaundice mainly has following several in the prior art: blue light box, blue light bed, blue light blanket etc. Blue light box belongs to the box closing irradiation treatment specific case structure of equipment needs, it is impossible to treat whenever and wherever possible; Blue light bed belongs to open therapeutic equipment, there is also one side therapeutic efficiency low, the shortcoming for the treatment of time length except existing and surrounding people is had impact; Blue light blanket belongs to open therapeutic equipment, and blue light is to surrounding people's fanout free region, but it is low to there is therapeutic efficiency, the shortcoming for the treatment of time length. Research shows, the intensity of blue light illumination has direct relation with bilirubinic drop-out value hourly in infant blood and rate of descent. Phototherapy effect increases with the increase of light intensity, uses high intensity phototherapy can avoid invalid phototherapy and reduce the phototherapy time. And existing therapeutic instrument to be generally difficult to the degree according to infant jaundice different with the region of irradiation and provide the setting of the blue light illumination parameter of optimization that can be for reference for medical personnel.
Summary of the invention
In order to overcome many deficiencies of tradition Phototherapeutic instrument, the jaundice that effectively treatment neonate is serious, the invention provides a kind of jaundice detection blue-light treatment instrument, the present invention has icteric index detection function, it is possible to provide reference data for medical personnel;Light intensity scalable, will reduce side effect greatly, be greatly shortened treatment time, extend the service life of instrument.
Jaundice detection blue-light treatment instrument, including blue light LED light source, control module, supply module, casing, prefocus cap, coaxial optical fiber and icteric index detection unit, the front end of described coaxial optical fiber is positioned at described prefocus cap, the end of described coaxial optical fiber is positioned at casing, described coaxial optical fiber end is provided with described icteric index detection unit and blue light LED light source, described icteric index detection unit is connected with described control module with described blue light LED light source, in addition, described supply module respectively with blue light LED light source, icteric index detection unit, control module to connect.
Further, the front end of described coaxial optical fiber is positioned at described prefocus cap, the end of described coaxial optical fiber is positioned at casing, described coaxial optical fiber includes outer core, SMIS, inner core, the end of outer core be provided with described blue light LED light source, described inner core and SMIS end disposed behind have described icteric index detection unit.
Further, described icteric index detection unit includes LED flash controller, detection light LED light source, photoelectric conversion device, described photoelectric conversion device includes spectroscope, first filter plate, second filter plate, first photodiode, second photodiode, described detection light LED light source is arranged on described SMIS end, described spectroscope is arranged on described inner core end, described spectroscopical right side is provided with described first filter plate, the disposed behind of described first filter plate has described first photodiode, described spectroscopical disposed behind have described second filter plate, the disposed behind of described second filter plate has described second photodiode, described first, second photodiode is connected with the logic control element of described control module respectively.
Further, described detection light LED light source includes blue light LED light source and green light LED light source, and the wavelength of described blue light LED light source is 450nm, and the wavelength of described green light LED light source is 550nm, described first filter plate is 450nm narrow band filter slice, and described second filter plate is 550nm narrow band filter slice.
Further, described coaxial optical fiber is encapsulated in the protection tube that can bend.
Further, helicitic texture is arranged at the top of described protection tube, and described protection tube is threadeded with described prefocus cap.
Further, the light radiation dominant wavelength ranges of described blue light LED light source is 400~520nm.
Further, described control module can carry out three grades of light modulations, and one grade of blue ray radiation power is 35 μ W cm-2 nm-1, and two grades of blue ray radiation power are 42 μ W cm-2 nm-1, and third gear blue ray radiation power is 52 μ W cm-2 nm-1.
Further, described supply module includes alternating current and turns DC power module, unidirectional current voltage changing module, LED constant current driving module, described alternating current turns DC power module and drives module to be connected with unidirectional current voltage changing module and LED constant current, additionally, described supply module is provided with reserve battery.
Further, described control module also includes temperature transducer unit, light source works current detecting unit, described temperature transducer unit is connected with described logic control element with described light source works current detecting unit, the temperature of described temperature transducer unit monitoring blue light LED light source and detection light LED light source, described light source works current monitoring unit monitoring blue light LED light source and detection light LED light source electric current, additionally, described control module is provided with display lamp, LCD segment encode screen, controls button, switch.
It is an advantage of the current invention that: blue-light treatment instrument volume is little, lightweight, different space requirements and therapeutic alliance needs can be met, can coordinate warm case flexibly, radiation table, the equipment such as infanette with the use of. Optical fiber can bend, and the convenient prefocus cap that regulates is to the distance between baby, it is to avoid baby is tanned severely, and blue light illumination can also be made to arrive the whole skin of baby by curved fiber. Blue light strength is adjustable, is divided into third gear, needed for meeting multiple therapeutic scheme, more can extend LED lamp bead service life. The mensuration icteric index that newborn skin appearance is quickly painless can be passed through, eliminate blood sampling and measure to the misery of neonate Dai Lai, reduce the expense of single detection, improve the work efficiency of medical personnel. And illumination power and the time of blue light LED light source can be automatically adjusted according to the result of icteric index detection.
Accompanying drawing explanation
In order to be illustrated more clearly that the embodiment of the present invention or technical scheme of the prior art, the accompanying drawing used required in embodiment or description of the prior art will be briefly described below, apparently, accompanying drawing in the following describes is only some embodiments of the present invention, for those of ordinary skill in the art, under the premise not paying creative work, it is also possible to obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is the control system schematic of jaundice detection blue-light treatment instrument;
Fig. 2 is the front view of jaundice detection blue-light treatment instrument;
Fig. 3 is the structural representation of jaundice detection blue-light treatment instrument.
Detailed description of the invention
In order to overcome many side effect and the unstability of tradition Phototherapeutic instrument, the jaundice that effectively treatment neonate is serious, the invention provides a kind of jaundice detection blue-light treatment instrument, the present invention has icteric index detection function, reference data, light intensity scalable can be provided for medical personnel, side effect will be reduced greatly, it is greatly shortened treatment time, extends the service life of instrument.
Below in conjunction with the accompanying drawing in the present invention, the technical scheme in the present invention is clearly and completely described, it is clear that described is only a part of embodiment of the present invention, rather than whole embodiments. Based on the embodiment in invention, the every other embodiment that those of ordinary skill in the art obtain under the premise not making creative work, broadly fall into the scope of invention protection.
As shown in Figure 1, 2, 3, jaundice detection blue-light treatment instrument, including blue light LED light source 15, control module, supply module, casing, prefocus cap 10, coaxial optical fiber 3 and icteric index detection unit. The front end of described coaxial optical fiber 3 is positioned at described prefocus cap 10, the end of described coaxial optical fiber 3 is positioned at casing, described coaxial optical fiber 3 end is provided with described icteric index detection unit and blue light LED light source 15, described icteric index detection unit is connected with described control module with described blue light LED light source 15, additionally, described supply module is connected with described blue light LED light source, icteric index detection unit, control module respectively.
Described coaxial optical fiber 3 is encapsulated in the protection tube that can bend, and helicitic texture is arranged at the top of described protection tube, and described protection tube is threadeded with described prefocus cap. Described coaxial optical fiber 3 includes outer core 21, SMIS 22, inner core 23, outer core 21 end is provided with blue light LED light source, the light radiation dominant wavelength ranges of described blue light LED light source 15 is 400~520nm, and the end of described SMIS 22 and inner core 23 is provided with described icteric index detection unit.
Described icteric index detection unit includes LED flash controller, detection light LED light source 16, photoelectric conversion device, and described photoelectric conversion device includes spectroscope the 24, first filter plate the 18, second filter plate the 19, first photodiode the 17, second photodiode 20. Described detection light LED light source 16 is arranged on the end of described SMIS 22, described detection light LED light source 16 includes blue light LED light source and green light LED light source, the wavelength of described blue light LED light source is 450nm, the wavelength of described green light LED light source is 550nm, and described spectroscope is arranged on the end of described inner core 23. The right side of described spectroscope 24 is provided with described first filter plate 18, described first filter plate is 450nm narrow band filter slice, the disposed behind of described first filter plate has described first photodiode 17, described spectroscopical disposed behind have described second filter plate 19, described second filter plate is 550nm narrow band filter slice, the disposed behind of described second filter plate has described second photodiode 20, and described first, second photodiode 20 is connected with the logic control element of described control module respectively.
Described supply module includes alternating current and turns DC power module, unidirectional current voltage changing module, LED constant current driving module, and described alternating current turns DC power module and drives module to be connected with unidirectional current voltage changing module and LED constant current, additionally, described supply module is provided with reserve battery.
Described control module also includes temperature transducer unit, light source works current detecting unit, described temperature transducer unit is connected with described logic control element with described light source works current detecting unit, the temperature of described temperature transducer unit monitoring blue light LED light source 15 and detection light LED light source 16, described light source works current monitoring unit monitoring blue light LED light source 15 and detection 16 electric currents of light LED light source, additionally, described control module is provided with display lamp 11, LCD segment encode screen 6, controls button 12, switchs 7.
The operation principle of the present invention: turn on the power switch 7, alternating current in casing 1 turns DC power module and 220V alternating current is converted to 24V DC voltage, 24V DC voltage drives module to power to blue light LED light source 15, detection light LED light source 16 respectively through LED constant current, by unidirectional current voltage changing module, 24V DC voltage is changed into 3.3V voltage to power to logic control element, in addition, it is charged to reserve battery, when product city is electrically disconnected, reserve battery startup work.
Undertaken dimming and fixed cycle operator by controlling button 12, three grades of light modulations can be carried out, one grade of blue ray radiation power is 35 μ W cm-2 nm-1, two grades of blue ray radiation power are 42 μ W cm-2 nm-1, third gear blue ray radiation power is 52 μ W cm-2 nm-1, push button signalling is transferred to logic control element, logic control element converts pwm control signal to light modulation monochrome information and is transferred to blue light LED light source 15 and dims output accordingly, logic control element is transferred to LCD segment encode screen 6 the information of light modulation and timing again, LCD segment encode screen 6 will reveal whether corresponding brightness and timing value, logic control element is transferred to display lamp 11 the status information of switch lamp and switch timing again and shows.
Logic control element controls described icteric index detection unit starting, the light that described detection light LED light source 16 sends is irradiated to skin from the SMIS 22 of coaxial optical fiber 3 by collecting lens 9, light wave is through the reflection of skin, reflection light is again through lens 9 optically focused, irradiate into spectroscope 24 from the inner core 23 of coaxial optical fiber 3, light wave after the optically focused mirror 24 that is split is divided into two bundles, wherein a branch of received by the first photodiode 17 after the first filter plate 18, another bundle is received by the second photodiode 20 after the second filter plate 19, first photodiode 17 and the second photodiode 20 convert optical signal into the signal of telecommunication, the signal of telecommunication is transferred on logic control element after processing and amplifying, icteric index is calculated by logic control element, comparison with historical data, logic control element light modulation monochrome information convert to pwm control signal be transferred to LED constant current drive module blue light LED light source 15 is dimmed output accordingly, logic control element is transferred to LCD segment encode screen 6 the information of light modulation and timing again.
Logic control element starts blue light LED light source, and the light that blue light LED light source 15 sends is transmitted to prefocus cap 10 from the outer core 21 of coaxial optical fiber 3, prefocus cap 10 be irradiated to skin. Described prefocus cap 10 is designed as tapered cups, threadeds with the protection tube on coaxial optical fiber 3 top, when rotating prefocus cap 10, it is possible to make prefocus cap 10, relative to coaxial optical fiber 3, relative displacement occur, reaches to assemble the effect for the treatment of luminous energy.
Logic control element is by the temperature of temperature transducer unit monitoring blue light LED light source, detection light LED light source, it is judged that whether blue light LED light source 15, detection light LED light source be overheated; The working current value of blue light LED light source, detection light LED light source is monitored by light source works current monitoring unit, judge whether blue light LED light source, detection light LED light source work, if blue light LED light source or detection light LED light source are overheated or do not work, logic control element can indicate by display lamp and close blue light LED light source 15 corresponding state information and detect light LED light source.
In sum, it is an advantage of the current invention that: volume is little, lightweight, different space requirements and therapeutic alliance needs can be met, can coordinate warm case flexibly, radiation table, the equipment such as infanette with the use of. Optical fiber can bend, and the convenient prefocus cap that regulates is to the distance between baby, it is to avoid baby is tanned severely, and blue light illumination can also be made to arrive the whole skin of baby by curved fiber. Blue light strength is adjustable, is divided into third gear, needed for meeting multiple therapeutic scheme, more can extend LED lamp bead service life. The mensuration icteric index that newborn skin appearance is quickly painless can be passed through, eliminate blood sampling and measure to the misery of neonate Dai Lai, reduce the expense of single detection, improve the work efficiency of medical personnel. And illumination power and the time of blue light LED light source can be automatically adjusted according to the result of icteric index detection.
Above content is in conjunction with concrete preferred implementation further description made for the present invention, it is impossible to assert that specific embodiment of the invention is confined to these explanations. For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, it is also possible to make some simple deduction or replace, protection scope of the present invention all should be considered as belonging to.

Claims (10)

1. jaundice detection blue-light treatment instrument, including blue light LED light source, control module, supply module, casing, prefocus cap, it is characterized in that, also include coaxial optical fiber and icteric index detection unit, the front end of described coaxial optical fiber is positioned at described prefocus cap, the end of described coaxial optical fiber is positioned at casing, described coaxial optical fiber end is provided with described icteric index detection unit and blue light LED light source, described icteric index detection unit is connected with described control module with described blue light LED light source, in addition, described supply module respectively with described blue light LED light source, icteric index detection unit, control module to connect.
2. jaundice detects blue-light treatment instrument according to claim 1, it is characterized in that, described coaxial optical fiber includes outer core, SMIS, inner core, the end of outer core be provided with described blue light LED light source, described inner core and SMIS end disposed behind have described icteric index detection unit.
3. jaundice detects blue-light treatment instrument according to claim 2, it is characterized in that, described icteric index detection unit includes LED flash controller, detection light LED light source, photoelectric conversion device, described photoelectric conversion device includes spectroscope, first filter plate, second filter plate, first photodiode, second photodiode, described detection light LED light source is arranged on the end of described SMIS, described spectroscope is arranged on the end of described inner core, described spectroscopical right side is provided with described first filter plate, the disposed behind of described first filter plate has described first photodiode, described spectroscopical disposed behind have described second filter plate, the disposed behind of described second filter plate has described second photodiode, described first photodiode, second photodiode is connected with the logic control element of described control module respectively.
4. jaundice detects blue-light treatment instrument according to claim 3, it is characterized in that, described detection light LED light source includes blue light LED light source and green light LED light source, the wavelength of described blue light LED light source is 450nm, the wavelength of described green light LED light source is 550nm, described first filter plate is 450nm narrow band filter slice, and described second filter plate is 550nm narrow band filter slice.
5. jaundice detects blue-light treatment instrument according to claim 1, it is characterised in that described coaxial optical fiber is encapsulated in the protection tube that can bend.
6. jaundice detects blue-light treatment instrument according to claim 5, it is characterised in that helicitic texture is arranged at the top of described protection tube, and described protection tube is threadeded with described prefocus cap.
7. jaundice detects blue-light treatment instrument according to claim 1, it is characterised in that the light radiation dominant wavelength ranges of described blue light LED light source is 400~520nm.
8. jaundice detects blue-light treatment instrument according to claim 1, it is characterized in that, described control module can carry out three grades of light modulations, and one grade of blue ray radiation power is 35 μ W cm-2 nm-1, two grades of blue ray radiation power are 42 μ W cm-2 nm-1, and third gear blue ray radiation power is 52 μ W cm-2 nm-1.
9. jaundice detects blue-light treatment instrument according to claim 1, it is characterized in that, described supply module includes alternating current and turns DC power module, unidirectional current voltage changing module, LED constant current driving module, described alternating current turns DC power module and drives module to be connected with unidirectional current voltage changing module and LED constant current, additionally, described supply module is provided with reserve battery.
10. jaundice detects blue-light treatment instrument according to claim 1, it is characterized in that, described control module also includes temperature transducer unit, light source works current detecting unit, described temperature transducer unit is connected with described logic control element with described light source works current detecting unit, the temperature of described temperature transducer unit monitoring blue light LED light source and detection light LED light source, described light source works current monitoring unit monitoring blue light LED light source and detection light LED light source electric current, in addition, described control module is provided with display lamp, LCD segment encode screen, control button, switch.
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Cited By (11)

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CN106267569A (en) * 2016-08-05 2017-01-04 武汉凯德立生物工程有限公司 A kind of temperature-controlled process and temperature control device
CN107115593A (en) * 2017-05-13 2017-09-01 盈泰(苏州)医疗科技有限公司 A kind of therapeutic instrument for neonatal jaundice
CN107456661A (en) * 2017-08-21 2017-12-12 武汉芸禾光电技术有限公司 A kind of blue light oral cavity therapeutic equipment
CN107961445A (en) * 2017-12-20 2018-04-27 深圳乐普智能医疗器械有限公司 Skin icterus tester
CN107998510A (en) * 2016-11-02 2018-05-08 广州美琳美健医疗科技有限公司 Baby's phototherapy film
CN109789312A (en) * 2016-09-29 2019-05-21 皇家飞利浦有限公司 For the wireless sensor system of energy can be collected used in the photo-therapeutic system
CN109985313A (en) * 2019-05-10 2019-07-09 天津工业大学 A kind of ohmeda biliblanket phototherapy light-source system based on COB-LED
CN111434309A (en) * 2019-01-11 2020-07-21 新加坡国立大学 Sensor and system for neonatal jaundice monitoring and management
CN111787847A (en) * 2018-02-26 2020-10-16 株式会社爱茉莉太平洋 Skin change measuring device and method using blue light, and blue light irradiation device
CN112604172A (en) * 2020-12-23 2021-04-06 重庆邮电大学 High-intensity blue light LED array phototherapy instrument device and self-feedback dimming method
CN116671869A (en) * 2023-06-21 2023-09-01 四川指南熊医疗科技有限公司 Jaundice measuring probe and jaundice detection device

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