CN102859361B - 癌症预后分析 - Google Patents

癌症预后分析 Download PDF

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Publication number
CN102859361B
CN102859361B CN201180008402.0A CN201180008402A CN102859361B CN 102859361 B CN102859361 B CN 102859361B CN 201180008402 A CN201180008402 A CN 201180008402A CN 102859361 B CN102859361 B CN 102859361B
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CN
China
Prior art keywords
cancer
flc
light chain
purposes
free
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Active
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CN201180008402.0A
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English (en)
Chinese (zh)
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CN102859361A (zh
Inventor
A·布拉德韦尔
G·米德
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Binding Site Group Ltd
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Binding Site Group Ltd
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Priority claimed from PCT/GB2011/050193 external-priority patent/WO2011095818A1/en
Publication of CN102859361A publication Critical patent/CN102859361A/zh
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • G01N33/6857Antibody fragments
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/50Determining the risk of developing a disease

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CN201180008402.0A 2010-02-05 2011-02-04 癌症预后分析 Active CN102859361B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1001950.3A GB201001950D0 (en) 2010-02-05 2010-02-05 Infection prognostic assay
GB1001950.3 2010-02-05
PCT/GB2011/050193 WO2011095818A1 (en) 2010-02-05 2011-02-04 Cancer prognosis assay

Publications (2)

Publication Number Publication Date
CN102859361A CN102859361A (zh) 2013-01-02
CN102859361B true CN102859361B (zh) 2015-06-17

Family

ID=42082582

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201180008402.0A Active CN102859361B (zh) 2010-02-05 2011-02-04 癌症预后分析
CN201180008422.8A Active CN102859362B (zh) 2010-02-05 2011-02-04 感染预后分析

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201180008422.8A Active CN102859362B (zh) 2010-02-05 2011-02-04 感染预后分析

Country Status (6)

Country Link
US (2) US20130217030A1 (https=)
EP (1) EP2531857B1 (https=)
JP (2) JP5818817B2 (https=)
CN (2) CN102859361B (https=)
GB (1) GB201001950D0 (https=)
WO (1) WO2011095820A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2519564A (en) * 2013-10-24 2015-04-29 Shared Band Ltd Multicast transmission over bonded broadband
US20170252364A1 (en) * 2014-07-30 2017-09-07 Mor Research Applications Ltd. Compositions for treatment of acute lymphoblastic leukemia and methods of use thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018576A1 (en) * 2002-07-24 2004-01-29 Dematteo Todd M. Bence Jones protein testing cassette
WO2005116651A2 (en) * 2004-05-24 2005-12-08 Diasys Corporation Method and device for testing for bence-jones protein
WO2006079816A1 (en) * 2005-01-27 2006-08-03 The Binding Site Limited Method of detecting or monitoring a malignant plasma cell disease

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4792529A (en) * 1985-10-18 1988-12-20 University Of Rochester Immunoassay of free kappa light chains for the detection of multiple sclerosis
IT1216698B (it) * 1988-04-01 1990-03-08 New Scient Co Spa Metodo per la determinazione della presenza di catene leggere libere in campioni di urina, complesso di preparati per l'esecuzione del metodo, e relativo reagente.
EP0862584B1 (en) 1995-11-03 2004-12-22 The Binding Site Limited Production of antibodies
US6322788B1 (en) * 1998-08-20 2001-11-27 Stanley Arthur Kim Anti-bacterial antibodies and methods of use
JP4438455B2 (ja) * 2004-03-04 2010-03-24 ヤマサ醤油株式会社 遊離ヒトイムノグロブリン軽鎖の測定法及びキット
US20090082304A1 (en) * 2004-11-12 2009-03-26 Northwestern University Methods of Treating Hematological Malignancies with Nucleoside Analog Drugs
US7781178B2 (en) * 2005-04-12 2010-08-24 Akira Matsumori Biomarker for diagnosing heart disease and the use thereof
JP2007292661A (ja) * 2006-04-26 2007-11-08 Akira Matsumori 活動性心筋炎の検出方法および検出試薬
GB0801609D0 (en) * 2008-01-29 2008-03-05 Binding Site The Ltd Hevylite diagnostic stain

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040018576A1 (en) * 2002-07-24 2004-01-29 Dematteo Todd M. Bence Jones protein testing cassette
WO2005116651A2 (en) * 2004-05-24 2005-12-08 Diasys Corporation Method and device for testing for bence-jones protein
WO2006079816A1 (en) * 2005-01-27 2006-08-03 The Binding Site Limited Method of detecting or monitoring a malignant plasma cell disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Borderline High Serum Free Light Chain κ/λ Ratios Are Seen Not Only in Dialysis Patients but Also in Non–Dialysis-Dependent Renal Impairment and Inflammatory States;George marshall;《Am J Clin Pathol》;20091231;第132卷;第309页 *

Also Published As

Publication number Publication date
JP2013519083A (ja) 2013-05-23
EP2531857A1 (en) 2012-12-12
GB201001950D0 (en) 2010-03-24
JP2013519082A (ja) 2013-05-23
EP2531857B1 (en) 2017-01-18
CN102859362A (zh) 2013-01-02
WO2011095820A1 (en) 2011-08-11
CN102859362B (zh) 2015-11-25
JP5818818B2 (ja) 2015-11-18
US20130217030A1 (en) 2013-08-22
CN102859361A (zh) 2013-01-02
JP5818817B2 (ja) 2015-11-18
US20130149792A1 (en) 2013-06-13

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