CN102854232A - 具有信号调节功能的生物传感器系统 - Google Patents
具有信号调节功能的生物传感器系统 Download PDFInfo
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- CN102854232A CN102854232A CN2012102810771A CN201210281077A CN102854232A CN 102854232 A CN102854232 A CN 102854232A CN 2012102810771 A CN2012102810771 A CN 2012102810771A CN 201210281077 A CN201210281077 A CN 201210281077A CN 102854232 A CN102854232 A CN 102854232A
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- China
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- value
- sample
- output signal
- correlativity
- analyte concentration
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/28—Electrolytic cell components
- G01N27/30—Electrodes, e.g. test electrodes; Half-cells
- G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
- G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
- G01N27/3273—Devices therefor, e.g. test element readers, circuitry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
Description
项 | 权重系数 | 系数标准误差 | T | P |
常数 | 133.52 | 48.35 | 2.76 | 0.006 |
R3/2 | 204.96 | 71.03 | 2.89 | 0.004 |
R4/3 | -356.79 | 96.47 | -3.70 | 0.000 |
(R3/2)(Graw) | -0.0408 | 0.1163 | -0.35 | 0.726 |
(R4/3)(Graw) | -0.0338 | 0.1812 | -0.19 | 0.852 |
(Temp)(R3/2) | -12.237 | 3.704 | -3.30 | 0.001 |
(Temp)(R4/3) | 15.565 | 5.115 | 3.04 | 0.002 |
Temp | -2.516 | 2.503 | -1.01 | 0.315 |
Graw | 0.0827 | 0.09661 | 0.86 | 0.392 |
项 | 权重系数 | 系数标准误差 | T | P |
常数 | 95.463 | 3.930 | 24.29 | 0.000 |
R3/2 | 177.66 | 68.22 | 2.60 | 0.010 |
R4/3 | -289.31 | 70.91 | -4.08 | 0.000 |
(R3/2)(Graw) | 7.9899×10-3 | 7.575×10-4 | 10.55 | 0.000 |
(Temp)(R3/2) | -11.221 | 3.550 | -3.16 | 0.002 |
(Temp)(R4/3) | 11.928 | 3.709 | 3.22 | 0.001 |
Claims (35)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12052508P | 2008-12-08 | 2008-12-08 | |
US61/120,525 | 2008-12-08 | ||
CN2009801490147A CN102239406A (zh) | 2008-12-08 | 2009-12-08 | 具有信号调节功能的生物传感器系统 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009801490147A Division CN102239406A (zh) | 2008-12-08 | 2009-12-08 | 具有信号调节功能的生物传感器系统 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN102854232A true CN102854232A (zh) | 2013-01-02 |
CN102854232B CN102854232B (zh) | 2015-12-02 |
Family
ID=42077436
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201210281077.1A Active CN102854232B (zh) | 2008-12-08 | 2009-12-08 | 具有信号调节功能的生物传感器系统 |
CN2009801490147A Pending CN102239406A (zh) | 2008-12-08 | 2009-12-08 | 具有信号调节功能的生物传感器系统 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2009801490147A Pending CN102239406A (zh) | 2008-12-08 | 2009-12-08 | 具有信号调节功能的生物传感器系统 |
Country Status (10)
Country | Link |
---|---|
US (3) | US8744776B2 (zh) |
EP (1) | EP2373984B1 (zh) |
JP (2) | JP5738770B2 (zh) |
CN (2) | CN102854232B (zh) |
BR (1) | BRPI0923342A2 (zh) |
CA (1) | CA2743440C (zh) |
HK (1) | HK1179346A1 (zh) |
MX (1) | MX2011005864A (zh) |
RU (1) | RU2509304C2 (zh) |
WO (1) | WO2010077660A1 (zh) |
Families Citing this family (27)
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US8529751B2 (en) * | 2006-03-31 | 2013-09-10 | Lifescan, Inc. | Systems and methods for discriminating control solution from a physiological sample |
US8778168B2 (en) | 2007-09-28 | 2014-07-15 | Lifescan, Inc. | Systems and methods of discriminating control solution from a physiological sample |
US8603768B2 (en) | 2008-01-17 | 2013-12-10 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
US8551320B2 (en) | 2008-06-09 | 2013-10-08 | Lifescan, Inc. | System and method for measuring an analyte in a sample |
ES2555215T3 (es) | 2008-12-08 | 2015-12-29 | Bayer Healthcare Llc | Composiciones de reactivo de bajo contenido salino total y sistemas para biosensores |
US9233788B2 (en) | 2010-01-22 | 2016-01-12 | Bayer Healthcare Llc | Biosensor desiccant system having enhanced measurement performance |
KR101929057B1 (ko) * | 2010-03-22 | 2018-12-13 | 바이엘 헬쓰케어 엘엘씨 | 바이오센서를 위한 잔여 보상 |
KR101971233B1 (ko) * | 2010-06-07 | 2019-04-22 | 바이엘 헬쓰케어 엘엘씨 | 2차 출력 신호를 포함하는 기울기-기반 보상 |
US9222910B2 (en) | 2010-06-07 | 2015-12-29 | Bayer Healthcare Llc | Underfill management system for a biosensor |
JP5889893B2 (ja) * | 2010-07-19 | 2016-03-22 | シラグ・ゲーエムベーハー・インターナショナルCilag GMBH International | 試料中の分析物を測定するためのシステム及び方法 |
JP2012032206A (ja) * | 2010-07-29 | 2012-02-16 | National Institute Of Advanced Industrial & Technology | 電気化学分析装置 |
TWI565943B (zh) | 2011-07-22 | 2017-01-11 | 拜耳保健公司 | 具有增進測量性能之生物感測器乾燥劑系統 |
EP3315123B1 (en) | 2011-09-21 | 2019-08-21 | Ascensia Diabetes Care Holdings AG | Analysis compensation including segmented signals |
US9903830B2 (en) | 2011-12-29 | 2018-02-27 | Lifescan Scotland Limited | Accurate analyte measurements for electrochemical test strip based on sensed physical characteristic(s) of the sample containing the analyte |
EP3276355B1 (en) * | 2013-03-14 | 2020-05-06 | Ascensia Diabetes Care Holdings AG | Normalized calibration of analyte concentration determinations |
WO2014159333A1 (en) * | 2013-03-14 | 2014-10-02 | Bayer Healthcare Llc | System error compensation of analyte concentration determinations |
US9933441B2 (en) * | 2013-03-14 | 2018-04-03 | Ascensia Diabetes Care Holdings Ag | Progressive approximation of sample analyte concentration |
US9459231B2 (en) | 2013-08-29 | 2016-10-04 | Lifescan Scotland Limited | Method and system to determine erroneous measurement signals during a test measurement sequence |
US9243276B2 (en) | 2013-08-29 | 2016-01-26 | Lifescan Scotland Limited | Method and system to determine hematocrit-insensitive glucose values in a fluid sample |
US11644434B2 (en) | 2015-05-15 | 2023-05-09 | Ascensia Diabetes Care Holdings Ag | Biosensor system analyte measurement |
US11268925B2 (en) | 2016-07-12 | 2022-03-08 | Ascensia Diabetes Care Holdings Ag | Intertwined electrical input signals |
CA3045090A1 (en) | 2016-12-05 | 2018-06-14 | Ascensia Diabetes Care Holdings Ag | Risk factor monitoring |
KR102179203B1 (ko) * | 2018-07-09 | 2020-11-16 | 주식회사 필로시스 | 혈당 센싱 데이터 판별 방법 및 장치 |
WO2020161099A1 (en) | 2019-02-05 | 2020-08-13 | Ascensia Diabetes Care Holdings Ag | Apparatus and methods for probing sensor operation of continuous analyte sensing and auto-calibration |
WO2020169719A1 (en) | 2019-02-22 | 2020-08-27 | Ascensia Diabetes Care Holdings Ag | Methods and apparatus for analyte concentration monitoring using harmonic relationships |
CN109884150B (zh) * | 2019-03-08 | 2021-05-14 | 武汉璟泓科技股份有限公司 | 一种红细胞积压校正方法及存储介质 |
US11678820B2 (en) | 2019-09-10 | 2023-06-20 | Ascensia Diabetes Care Holdings Ag | Methods and apparatus for information gathering, error detection and analyte concentration determination during continuous analyte sensing |
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-
2009
- 2009-12-08 CN CN201210281077.1A patent/CN102854232B/zh active Active
- 2009-12-08 CN CN2009801490147A patent/CN102239406A/zh active Pending
- 2009-12-08 RU RU2011128010/28A patent/RU2509304C2/ru not_active IP Right Cessation
- 2009-12-08 JP JP2011540829A patent/JP5738770B2/ja active Active
- 2009-12-08 WO PCT/US2009/067150 patent/WO2010077660A1/en active Application Filing
- 2009-12-08 MX MX2011005864A patent/MX2011005864A/es active IP Right Grant
- 2009-12-08 BR BRPI0923342A patent/BRPI0923342A2/pt not_active IP Right Cessation
- 2009-12-08 CA CA2743440A patent/CA2743440C/en not_active Expired - Fee Related
- 2009-12-08 EP EP09775450.1A patent/EP2373984B1/en active Active
-
2011
- 2011-06-06 US US13/153,793 patent/US8744776B2/en active Active
-
2013
- 2013-06-11 HK HK13106879.8A patent/HK1179346A1/zh not_active IP Right Cessation
-
2014
- 2014-04-01 US US14/231,874 patent/US10656113B2/en active Active
-
2015
- 2015-04-22 JP JP2015087322A patent/JP6002274B2/ja active Active
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2020
- 2020-05-08 US US16/870,703 patent/US20200271615A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP6002274B2 (ja) | 2016-10-05 |
US20140209460A1 (en) | 2014-07-31 |
JP5738770B2 (ja) | 2015-06-24 |
EP2373984A1 (en) | 2011-10-12 |
CA2743440A1 (en) | 2010-07-08 |
US10656113B2 (en) | 2020-05-19 |
RU2509304C2 (ru) | 2014-03-10 |
RU2011128010A (ru) | 2013-01-20 |
CA2743440C (en) | 2017-07-18 |
US20200271615A1 (en) | 2020-08-27 |
EP2373984B1 (en) | 2022-11-30 |
WO2010077660A1 (en) | 2010-07-08 |
MX2011005864A (es) | 2011-06-20 |
US20110297554A1 (en) | 2011-12-08 |
CN102854232B (zh) | 2015-12-02 |
JP2012511160A (ja) | 2012-05-17 |
CN102239406A (zh) | 2011-11-09 |
JP2015155919A (ja) | 2015-08-27 |
BRPI0923342A2 (pt) | 2016-01-12 |
US8744776B2 (en) | 2014-06-03 |
HK1179346A1 (zh) | 2013-09-27 |
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Effective date of registration: 20160926 Address after: Basel Patentee after: BAYER HEALTHCARE LLC Address before: American New York Patentee before: Bayer Corp. |