Summary of the invention
The purpose of this invention is to provide a kind of determined curative effect, have no side effect, technique simply treats umbilica sticking plaster of dysmenorrhea and preparation method thereof.
The umbilica sticking plaster for the treatment of dysmenorrhea of the present invention is by the crude drug of following parts by weight: 120~180 parts of Radix Angelicae Sinensis (processed with wine), 50~80 parts of Rhizoma Corydalis, 50~80 parts of Cortex Cinnamomis, 100~150 parts of the Radix Paeoniae Albas, 80~120 parts of Rhizoma Cyperis, 80~120 parts of Herba Pogostemoniss, 20~40 parts of Rhizoma Chuanxiongs, 50~80 parts of Rhizoma Zingiberiss, 50~80 parts of Fructus Anisi Stellatis, 20~40 parts of the Radix Aucklandiae; Be equipped with adjuvant: 310~485 parts in 310~485 parts in vaseline, Cera Flava are made.
The preparation method of this umbilica sticking plaster may further comprise the steps: a, Radix Angelicae Sinensis (processed with wine), Rhizoma Corydalis, Cortex Cinnamomi, the Radix Paeoniae Alba, Rhizoma Cyperi, Herba Pogostemonis, Rhizoma Chuanxiong, Rhizoma Zingiberis, Fructus Anisi Stellati, the Radix Aucklandiae are mixed according to described parts by weight, be ground into the above medicated powder of 100 orders; B, with the vaseline of described parts by weight 38 ℃~60 ℃ lower fusings, add the Cera Flava of described parts by weight, be warming up to 62 ℃~67 ℃ fully after the fusing, add the medicated powder of described parts by weight, rapid stirring is even, cooling and get final product.
Preferably, umbilica sticking plaster of the present invention can be by the crude drug of following parts by weight: 150 parts of Radix Angelicae Sinensis (processed with wine), 60 parts of Rhizoma Corydalis, 60 parts of Cortex Cinnamomis, 120 parts of the Radix Paeoniae Albas, 100 parts of Rhizoma Cyperis, 100 parts of Herba Pogostemoniss, 30 parts of Rhizoma Chuanxiongs, 60 parts of Rhizoma Zingiberiss, 60 parts of Fructus Anisi Stellatis, 30 parts of the Radix Aucklandiae; Be equipped with adjuvant: 385 parts in 385 parts in vaseline, Cera Flava are made.
Radix Angelicae Sinensis can be enriched blood, and invigorates blood circulation regulating menstruation, pain relieving, intestine moistening; Rhizoma Corydalis has promoting blood circulation to remove blood stasis, the function of promoting the circulation of QI pain relieving; It is fiery supporing yang that Cortex Cinnamomi has benefit, let the fire back to its origin, dispersing cold for relieving pain, the effect of promoting blood circulation to restore menstrual flow; The Radix Paeoniae Alba cures mainly pathogen stomachache, and is broken hard long-pending except arthralgia due to stagnation of blood, cold and heat, hernia abdominal mass, pain relieving, diuresis, QI invigorating; The Rhizoma Cyperi resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving is used for stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type stomachache, distending pain of the breast; Agastachel patchoule summer heat dispelling induces sweat, removing dampness to restore normal function of the stomach, is used for the summertime flu, the cold and heat headache, and breast gastral cavity painful abdominal mass is vexed, and vomiting is had loose bowels, vomiting during pregnancy, nasal sinusitis, tinea manus and pedis; The Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping is used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia; The Rhizoma Zingiberis warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, the dampness expectorant, warming the lung to resolve fluid-retention is used for coldness and pain in the epigastrium, and vomiting is had loose bowels, and YANG-depletion is fainted contrary, and cold fluid-retention is breathed with cough, arthralgia due to cold-dampnes; The Fructus Anisi Stellati cold expelling is regulated the flow of vital energy, and pain relieving is used for colic of cold type stomachache, chills and pain of the waist and kness, gastrofrigid vomiting, epigastric pain, the disturbance of lower legs due to pathogenic cold and dampness; Radix Aucklandiae promoting the circulation of QI to relieve pain, warming middle-JIAO for easing the stomach is used for chest and abdomen swelling and pain, and the dysentery tenesmus is had loose bowels in vomiting.All medicine compatibilities, warming the meridian and activating blood circulation, treatment dysmenorrhea effect are remarkable.
The present invention makes umbilica sticking plaster with said medicine and uses; compared with prior art have following characteristics: Cera Flava has the effect of astringent therapy, granulation promoting, pain relieving, detoxifcation; vaseline has water proofing property; a kind of extraordinary moisturizing articles for use; be used for the ointment of preparation medicine and the raw material that the skin care ointment is used; with its substrate that adopts as umbilica sticking plaster, stable chemical nature can impel the principal agent volatilization to absorb.Umbilica sticking plaster preparation technology of the present invention is easy, be conducive to umbilicus penetrates and absorbs, and especially the skin of umbilicus place is reacted without allergy, more has no side effect.In addition, the bad toxic and side effects that can avoid some oral drugs that the generations such as patient's liver kidney are brought.
Relevant clinical data is as follows: in the 285 routine cases, oldest 41 years old, minimum 18 years old, be divided at random three groups, respectively 98,92,95 examples.Three groups of cases are Epidemiological Analysis difference not statistically significant by statistics at aspects such as ages, has comparability.All cases are all made a definite diagnosis with reference to diagnosis basis and efficacy assessment standard in " traditional Chinese medical science disease Standardization of diagnosis and curative effect ".
Diagnosis basis: menstrual period or before and after row lower abdomen pain, pain and waist sacrum are very then fainted.Be periodical attack.Be apt to occur in young maiden.Suffer from abdominal pain due to the eliminating pelvic cavity organic disease.
Therapeutic Method: three group 98,92,95 examples are accepted respectively embodiment 1, embodiment 2, embodiment 3 umbilicus patch clinical treatments, are affixed on umbilical part, change once in 48 hours.
Efficacy evaluation: cure: pain disappears, and recurrence is seen at continuous 3 menstrual cycle ends.Take a turn for the better: pain relief or pain disappear, but can not keep more than 3 months.Do not heal: pain has no improvement.
Curative effect comparative statistics result is as follows after three groups of case treatments:
Group |
Embodiment 1 |
Embodiment 2 |
Embodiment 3 |
The example number |
98 |
92 |
95 |
Cure (n%) |
20(20.4%) |
19(20.6%) |
18(19%) |
Take a turn for the better (n%) |
63(64.2%) |
60(65.2%) |
62(65.3%) |
Do not heal (n%) |
15(15.4%) |
13(14.2%) |
15(15.7%) |
Anaphylaxis (n%) |
0(0%) |
0 (0%) |
0 (0%) |
Total effective rate (n%) |
84.6% |
85.8% |
84.3% |
The specific embodiment
The invention will be further described for embodiment plan given below; but can not be interpreted as it is limiting the scope of the invention; content still belongs to protection scope of the present invention to nonessential improvement and adjustment more of the present invention to those skilled in the art according to the present invention.
Embodiment 1: get Radix Angelicae Sinensis (processed with wine) 150 grams, Rhizoma Corydalis 60 grams, Cortex Cinnamomi 60 grams, the Radix Paeoniae Alba 120 grams, Rhizoma Cyperi 100 grams, Herba Pogostemonis 100 grams, Rhizoma Chuanxiong 30 grams, Rhizoma Zingiberis 60 grams, Fructus Anisi Stellati 60 grams, the Radix Aucklandiae 30 grams, mix after 35 ℃ of lower oven dry, grinding and processing becomes the above medicated powder of 100 orders.
First with 385 gram vaseline 50 ℃ of lower fusings, add 385 gram Cera Flavas, heat to 63 ℃ fully after the fusing, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted ring size 2cm in 6cm * 7cm() the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose 1.5 grams.The finished product that processes is packed with 8cm * 12cm compound membrane bag, and one pastes one bag.
Embodiment 2: get Radix Angelicae Sinensis (processed with wine) 120 grams, Rhizoma Corydalis 50 grams, Cortex Cinnamomi 50 grams, the Radix Paeoniae Alba 100 grams, Rhizoma Cyperi 80 grams, Herba Pogostemonis 80 grams, Rhizoma Chuanxiong 20 grams, Rhizoma Zingiberis 50 grams, Fructus Anisi Stellati 50 grams, the Radix Aucklandiae 20 grams, mix after 67 ℃ of lower oven dry, grinding and processing becomes the above medicated powder of 100 orders.
First with 310 gram vaseline 60 ℃ of lower fusings, add 310 gram Cera Flavas, heat to 65 ℃ fully after the fusing, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted 7cm * 8cm(internal ring is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3 grams.The finished product that processes is packed with 8cm * 12cm compound membrane bag, and one pastes one bag.
Embodiment 3: get Radix Angelicae Sinensis (processed with wine) 180 grams, Rhizoma Corydalis 80 grams, Cortex Cinnamomi 80 grams, the Radix Paeoniae Alba 150 grams, Rhizoma Cyperi 120 grams, Herba Pogostemonis 120 grams, Rhizoma Chuanxiong 40 grams, peeling Rhizoma Zingiberis 80 grams, Fructus Anisi Stellati 80 grams, the Radix Aucklandiae 40 grams, mix after 50 ℃ of lower oven dry, grinding and processing becomes the above medicated powder of 100 orders.
First with 485 gram vaseline 38 ℃ of lower fusings, add 485 gram Cera Flavas, heat to 62 ℃ fully after the fusing, add medicated powder, rapid stirring is even, cooling.
Cooled umbilica sticking plaster is inserted 7cm * 8cm(internal ring is of a size of 2.5cm) the internal ring of non-woven fabrics umbilica sticking plaster cloth pad in, dose is 3.1 grams.The finished product that processes is packed with 8cm * 12cm compound membrane bag, and one pastes one bag.