CN102823859B - Composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate - Google Patents
Composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate Download PDFInfo
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- CN102823859B CN102823859B CN2012103237594A CN201210323759A CN102823859B CN 102823859 B CN102823859 B CN 102823859B CN 2012103237594 A CN2012103237594 A CN 2012103237594A CN 201210323759 A CN201210323759 A CN 201210323759A CN 102823859 B CN102823859 B CN 102823859B
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- honeysuckle
- matrimony vine
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Abstract
The invention relates to a composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate. The invention relates to nutrition health care food, in particular to the composition with the advantages that the effects of tonifying the kidney, nourishing the liver and supplementing the calcium, the composition is suitable for being taken for a long time, and people cannot easily suffer from excessive internal heat. The composition comprises 60 to 100 weight parts of medlar, 10 to 100 weight parts of chrysanthemum or honeysuckle and 80 to 200 weight parts of calcium gluconate.
Description
Technical field
The present invention relates to nutraceutical and health food, particularly a kind of have kidney tonifying, nourishing the liver, a supplement calcium, is fit to take for a long time and the composition that is difficult for getting angry.
Background technology
Calcium directly influences outside the height except being the base stock of skeleton development, also has other important physical functions in vivo.These functions are to safeguarding the health of body, and what guarantee that normal growth grows has important function smoothly.Because people's eating habit and individual absorption difference can not satisfy body to the demand of calcium,, calcium needs a kind of element of taking when growing again so being people everyday.Confirm to existing scientific research from theory of traditional Chinese medical science: replenishing the calcium needs kidney tonifying, kidney tonifying can promote absorption and the utilization of calcium, promote skeletal growth to grow, " matrimony vine calcium " product as market sale, good calcium supplementing effect is arranged, but Time of Administration length can cause the symptom of getting angry, influence it and continue to take, because the thermogenetic effect of matrimony vine is quite strong, the physique of especially easily getting angry more is difficult for taking, and simple replenishing the calcium also causes side effects such as dry, constipation easily, matrimony vine and calcium meet, and easier causing got angry, and influence follow-up taking, incur loss through delay calcareous replenishing, influence effect of supplemented calcium.
To sum up, need a kind ofly to be difficult for getting angry with being fit to when mending take for a long time and can to strengthen the product of replenishing the calcium of effect at the kidney bone.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, a kind of composition that is difficult for getting angry with being fit to when mending take for a long time at the kidney bone is provided.Said composition is characterised in that it contains wolfberry fruit extract, chrysanthemum extract or Honegsukle flower P.E, calcium gluconae.The present composition combines supplementing calcium and nourishing kidney with clearing heat and cooling blood, replenish the calcium with kidney tonifying in be difficult for causing and get angry, be fit to take for a long time.
The traditional Chinese medical science is thought " kidney master bone ", kidney qi is enriched, then sclerotin is stocky, thus replenish the calcium at first kidney tonifying, and cause bad side effects such as dry, hot eyes, dysphoria with smothery sensation, pharyngalgia kidney tonifying the time easily, get angry and to cause immunity of organism to reduce, the viscera function disorder influences blood circulation, hinders absorption and the utilization of nutriment, the interruption that causes replenishing the calcium influences and calcareous replenish and absorb.So the present invention adds chrysanthemum or the honeysuckle of clearing heat and cooling blood on this basis, can alleviate the burning hot bias of help medicine matrimony vine, removing pattogenic heat from the blood and toxic material from the body, the toxin in the cleaning blood, calcium can better be absorbed and utilize, and be fit to long-term take and can increase the effect of replenishing the calcium.
Matrimony vine
Matrimony vine has red matrimony vine and black matrimony vine to return Liver Channel; Kidney channel; Lung channel.Tonifying kidney and benefiting sperm is arranged, fill up the vigour effect, it is thanks to smart to be used for consumptive disease, soreness of waist and knee joint, dizzy tinnitus, impotence and seminal emission etc.
Chrysanthemum
Chrysanthemum, sweet, bitter, be slightly cold, Here it is medicine chrysanthemum can be divided into 4 big classes to the medicine chrysanthemum, namely spends chrysanthemum, chrysanthemum, tribute chrysanthemum and FLOS CHRYSANTHEMI from Hangzhou of China four classes in vain, and chrysanthemum is returned lung, Liver Channel, the wind heat-clearing of loosing, flat liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, red eye, swell pain, and eyes is dim-sighted.Chrysanthemum is classified chrysanthemum as on medicine product in Shennong's Herbal, think " obey sharp vim and vigour for a long time, make light of one's life by commiting suicide anti-prolong life always ".Medicinal part: capitulum active ingredient: chrysanthemum flavones.
Honeysuckle
Honeysuckle is described as clearing heat and detoxicating good medicine from ancient times.The sweet cold air fragrance of its property, clear heat with drugs of sweet flavour and cold nature and not injuring one's stomach, fragrance reaches thoroughly and can be eliminating evil.Honeysuckle can dispelling wind-heat, kind removing summer-heat blood poison also, and wherein effective ingredient is chlorogenic acid, isochlorogenic acid.
Calcium gluconae
Calcium is the maximum and most active element of body burden, participate in from bone formation, contraction of muscle, heartbeat, nerve and brain thinking activities, until the whole life process of growing, eliminating fatigue, brain tonic and intelligence development and delay senility etc. of human body.Calcium comprises: all edible calcium containing compound and derived materials thereof such as calcium carbonate, calcium phosphate, calcium acetate, l threonic acid, amino acid chelated calcium, Calcium Ascorbate, calcium gluconae, oyster calcium, Calcium, milk calcium, complexing calcium, BIOLOGICAL CALCIUM.
According to the present invention, a kind of composition that contains matrimony vine, chrysanthemum or honeysuckle, calcium gluconae is provided, comprising: the calcium gluconae of the chrysanthemum of the matrimony vine of 60-100 weight portion, 10-100 weight portion or honeysuckle, 80-200 weight portion.Described composition is difficult for causing with being fit to again when mending take for a long time at the kidney bone gets angry, and heightens the effect of a treatment.
According to an aspect of the present invention, composition of the present invention is applied to health food or medicine, for example makes pharmaceutically acceptable all solid-state or liquid formulations such as tablet, capsule, particle, powder, paste, pill, dripping pill, oral liquid and beverage and tea in bag etc.Said composition realizes that auxiliary material that above-mentioned all kinds of formulation is used and consumption are by receptible on the formulation and meet auxiliary material and the consumption of national interpolation standard.
According to a further aspect in the invention, composition of the present invention also can contain 10-200 weight portion collagen.In bone, organic 70%-80% is collagen, and it constitutes network structure with the form of collagenous fibres and elastomer, in order to effective deposition and fixing calcareous, thus tough and tensile strong bone, the loss of prevention calcium.
In a specific embodiment, described matrimony vine comprises red matrimony vine and black matrimony vine, comprises its wolfberry fruit powder, wolfberry fruit extract, its physiologically acceptable salt and derivative thereof.
In a specific embodiment, the chrysanthemum of telling comprises spends chrysanthemum, chrysanthemum, tribute chrysanthemum and FLOS CHRYSANTHEMI from Hangzhou of China in vain, comprises its chrysanthemum powder, chrysanthemum extract, chrysanthemum flavones, its physiologically acceptable salt and derivative thereof.
In a specific embodiment, described honeysuckle comprises honeysuckle powder, Honegsukle flower P.E, wherein chlorogenic acid or isochlorogenic acid, its physiologically acceptable salt and derivative thereof.
Alternatively, described calcium gluconae also can be other calcium containing compounds or its pharmaceutically acceptable calcium salt, its derivative.Described calcium comprises: calcium carbonate, calcium phosphate, calcium acetate, oyster calcium, Calcium, l threonic acid, amino acid chelated calcium, Calcium Ascorbate, calcium gluconae, milk calcium, complexing calcium, BIOLOGICAL CALCIUM and all edible calcium containing compound and derived materials thereof of wherein not mentioning.
The present invention has overcome matrimony vine calcium and has easily caused the bad reaction of getting angry at the kidney bone when mending, and has solved its difficult shortcoming of taking for a long time, has strengthened its effect of supplemented calcium.
The specific embodiment
Further specify the present invention by the following examples, yet the embodiment of the invention and the example just are used for explanation the present invention, should by any way described embodiment be interpreted as the scope of the invention is limited.
Unless otherwise indicated, each used composition raw material of the present invention is commercial getting.
The preparation of embodiment 1, the present composition
Utilize the material of listing in the following table to be raw material, evenly mixing can prepare some compositions of the present invention.It should be understood that as required and make pharmaceutically receptible all composition products solid-state or liquid formulation such as tablet, capsule, particle, powder, cream, ball, dripping pill, oral liquid, beverage and tea in bag with the additive-based required auxiliary material of prior art.
| Example | Raw material |
| 1 | Wolfberry fruit extract 60 grams; Chrysanthemum extract 100 grams:; Calcium gluconae 200 grams |
| 2 | Wolfberry fruit extract 100 grams; Chrysanthemum extract 10 grams:; Calcium gluconae 80 grams |
| 3 | Wolfberry fruit extract 85 grams; Chrysanthemum extract 85 grams:; Calcium gluconae 85 grams |
The prevention of embodiment 2, the present composition is replenished the calcium and is got angry and the contrast experiment of effect
Clinical data: choose this experimental example 32 examples, be divided into 4 groups at random, of the present invention group totally 3 groups is respectively example 1,2,3 groups, every group of 8 examples, sex: women 15 examples, male 17 examples; Control group 8 examples, women 5 examples, male 3 examples, age 30-50 year; Be lower than normal range (NR) through the blood calcium detection, with the calcium deficiency symptom, all experimental examples eliminating drys, pharyngalgia etc. are got angry and infection symptoms.Method is, control group gives the composition of wolfberry fruit extract 60 weight portions and calcium gluconae 200 weight portions, everyone 800 milligrams/day, take at twice, of the present invention group of composition that gives preparation in the example 1,2,3 respectively, taken at twice by everyone 900 milligrams/day, it is 1 course for the treatment of that each group is 30 days, statistics after 1 course for the treatment of.
The result shows: of the present invention group only example 2 examples are arranged with the dry symptom for 2 groups, wherein 1 example has slight pharyngalgia, all the other each groups are not found senses of discomfort such as dry, pharyngalgia, each routine calcium deficiency symptom all disappears, efficient is 100%, total prevention rate of getting angry is 83%.Control group has 4 examples taking the 10th day with dry, pharyngalgia, and stop continuing to take, and serious dry appears in 2 examples, alleviates to some extent after advising its many drinking-water, the slight pharyngalgia of 1 example and with nose Niu, 1 example is not seen ill symptoms, the side reaction prevention rate is 12.5%.Its remission 5 examples, efficient is 62.25%, control group has 4 examples to stop taking, and has influenced effect of supplemented calcium.Show that of the present invention group has effectively alleviated the warm of matrimony vine when the kidney bone is with benefit, can take for a long time, finish the process of replenishing the calcium.Its effect of replenishing the calcium also is better than control group.
Other embodiment
Utilize the experiment of other proportionings repetitions embodiment 1-3 in the scope of the invention, compare with corresponding reference examples, all can obtain identical/similar result (data not shown goes out), the present composition has kidney tonifying, calcium supplementing effect, and is difficult for getting angry.
The present invention only is that example is set forth with above-described embodiment, and other proportionings of the concrete proportioning shown in the embodiment and the unshowned present composition all can be used for the present invention and they all can realize technique effect of the present invention.
Claims (7)
1. Chinese medicine composition, it is made up of matrimony vine, chrysanthemum or honeysuckle, calcium gluconae, and wherein by weight, matrimony vine accounts for that 60-100 weight portion, chrysanthemum or honeysuckle account for the 10-100 weight portion, calcium gluconae accounts for the 80-200 weight portion.
2. composition according to claim 1, wherein said matrimony vine is selected from red matrimony vine and black matrimony vine.
3. composition according to claim 1, wherein said chrysanthemum is selected from spends chrysanthemum, chrysanthemum, tribute chrysanthemum and FLOS CHRYSANTHEMI from Hangzhou of China in vain.
4. composition according to claim 1, wherein said honeysuckle is selected from honeysuckle powder or Honegsukle flower P.E.
5. Chinese medicine composition, it is made up of matrimony vine, chrysanthemum or honeysuckle, calcium gluconae and collagen, wherein by weight, matrimony vine accounts for 60-100 weight portion, chrysanthemum or honeysuckle and accounts for that 10-100 weight portion, calcium gluconae account for the 80-200 weight portion, collagen accounts for the 10-200 weight portion.
6. composition according to claim 1 or 5, wherein said calcium gluconae is substituted by calcium carbonate, calcium phosphate, calcium acetate, l threonic acid, amino acid chelated calcium, Calcium Ascorbate, oyster calcium, Calcium or milk calcium.
7. a health food or medicine, by each described composition of claim 1-6 and pharmaceutically receptible excipient form, described health food or medicine adopt the formulation of tablet, capsule, particle, powder, paste, pill, oral liquid or tea in bag.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103237594A CN102823859B (en) | 2012-08-28 | 2012-08-28 | Composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103237594A CN102823859B (en) | 2012-08-28 | 2012-08-28 | Composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate |
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| Publication Number | Publication Date |
|---|---|
| CN102823859A CN102823859A (en) | 2012-12-19 |
| CN102823859B true CN102823859B (en) | 2013-09-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012103237594A Expired - Fee Related CN102823859B (en) | 2012-08-28 | 2012-08-28 | Composition comprising medlar, chrysanthemum or honeysuckle and calcium gluconate |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103169095B (en) * | 2013-04-13 | 2014-11-05 | 洛阳本草生物制药股份有限公司 | Method for preparing barbary wolfberry fruit powder by adding chrysanthemum extract liquid |
| CN103380928B (en) * | 2013-06-11 | 2015-03-18 | 十堰渝川食品有限公司 | Shine skin papaya-chrysanthemum-wolfberry composite beverage and preparation method thereof |
| CN103404932A (en) * | 2013-07-08 | 2013-11-27 | 黄裕兵 | Chrysanthemum crystal |
| CN112754019A (en) * | 2020-12-23 | 2021-05-07 | 河南九天生物科技有限公司 | Composition containing 25 hydroxyl d3 and calcium gluconate and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229273A (en) * | 2007-11-07 | 2008-07-30 | 杨伯涛 | Medlar multi-vitamins calcium tablet |
| CN102273704A (en) * | 2011-06-16 | 2011-12-14 | 牟一心 | Calcium-zinc honeysuckle flower leaf beverage and preparation method thereof |
-
2012
- 2012-08-28 CN CN2012103237594A patent/CN102823859B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229273A (en) * | 2007-11-07 | 2008-07-30 | 杨伯涛 | Medlar multi-vitamins calcium tablet |
| CN102273704A (en) * | 2011-06-16 | 2011-12-14 | 牟一心 | Calcium-zinc honeysuckle flower leaf beverage and preparation method thereof |
Non-Patent Citations (4)
| Title |
|---|
| 中药成方制剂卷》.2011,第551页. |
| 任英梅.补钙更要补胶原蛋白.《别让食物害了你》.2007,第376页. * |
| 国家药典委员会.杞菊地黄丸.《中华人民共和国药典临床用药须知：2010年版• |
| 国家药典委员会.杞菊地黄丸.《中华人民共和国药典临床用药须知:2010年版•中药成方制剂卷》.2011,第551页. * |
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| CN102823859A (en) | 2012-12-19 |
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Effective date of registration: 20201127 Address after: Room 218, office building, entrepreneurship Park, small and medium sized enterprises, No. 5, Luhua East Street, Bayannur economic and Technological Development Zone, Inner Mongolia Autonomous Region Patentee after: Inner Mongolia red glory Biotechnology Co.,Ltd. Address before: Room 30-3-401, Sijihuacheng, Linhe District, Bayannur City, Inner Mongolia Autonomous Region Patentee before: Meng Linggang |
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