CN102823792B - Soft propolis astragalus mongholicus capsule and preparation method thereof - Google Patents
Soft propolis astragalus mongholicus capsule and preparation method thereof Download PDFInfo
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- CN102823792B CN102823792B CN2012103083295A CN201210308329A CN102823792B CN 102823792 B CN102823792 B CN 102823792B CN 2012103083295 A CN2012103083295 A CN 2012103083295A CN 201210308329 A CN201210308329 A CN 201210308329A CN 102823792 B CN102823792 B CN 102823792B
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Abstract
The invention discloses a soft propolis astragalus mongholicus capsule and a preparation method thereof. Filler components of the soft propolis astragalus mongholicus capsule includes, by weight, 15-20% of astragalus mongholicus extracts, 13-15% of propolis extracts, 62-65% of soybean oil and 4-5% of beewax; a capsule body is made of components including, by weight, 40-43% of gelatin, 35-40% of purified water, 18-23% of glycerol and 0.5-0.7% of brown ferric oxide. Besides reserving functions of broad-spectrum antibiosis of propolis and astragalus mongholicus, anti-inflammation and analgesia, histocyte regeneration acceleration, antitumous effect, resistance to hepatic pathological changes, treatment for gastric ulcer and oral disease, anti-aging, anti-stress, reduction of blood pressure, triglyceride and cholesterol and insomnia resistance, the healthcare functions of the soft propolis astragalus mongholicus capsule, including spleen and qi tonifying, lung tonifying and basis solidifying and blood sugar reduction are enhanced.
Description
Technical field
The present invention relates to field of health care food, be specifically related to a kind of propolis Radix Astragali soft capsule and preparation method thereof.
Background technology
The propolis resin (natural gum) that to be honeybee gather from plant gemma or trunk is sneaked into a kind of colloidal solid thing with aromatic odor that the secretion of palatine gland on it, wax gland processes.Contain the flavone compound more than 70 kinds, multiple alkene, terpenoid, amino acid, vitamin B complex, mineral matter and the trace element of trace, multiple organic acid etc. in the propolis, propolis has broad-spectrum antiseptic, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, treatment gastric ulcer, the function of mouth disease, propolis to reduce the function of triglyceride, cholesterol and adjusting blood sugar in addition.The Radix Astragali is the root of leguminous herbaceous plant's astragalus mongolicus, Astragalus membranacus, and scientific research shows that the Radix Astragali contains various trace elements such as saponin, sucrose, polysaccharide, several amino acids, folic acid and selenium, zinc, copper.Have strengthen body's immunity, protect the liver, diuresis, anti-ageing, anti-stress, step-down and antibacterial action more widely, can eliminate experimental nephritic proteinuria, the enhancing myocardial contractive power, effects such as adjusting blood-sugar content are human health cares, the treasure of auxiliary curing.
Propolis Radix Astragali soft capsule is that the extract with propolis and the Radix Astragali processes according to scientific formula, though natural propolis and the Radix Astragali have stronger health protection and therapeutic action, but, the consumer can't directly eat, by the advanced person, the propolis Radix Astragali soft capsule of the explained hereafter of science, both kept all active ingredient of propolis and the Radix Astragali, solved the edible inconvenient difficult problem of natural propolis and the Radix Astragali again, simultaneously, by the invention prescription, having increased this product invigorates the spleen and benefits qi, the function of blood sugar is shown and reduced to tonifying lung admittedly, gives human health-care good product for enjoyment the Nature fast way is provided.
Summary of the invention
The invention provides a kind of propolis Radix Astragali soft capsule and preparation method thereof, propolis Radix Astragali soft capsule of the present invention except the broad-spectrum antiseptic that has kept propolis, the Radix Astragali, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, hepatic disease, treatment gastric ulcer, mouth disease, anti-ageing, anti-stress, step-down, reduction triglyceride, cholesterol, insomnia and the antidotal effect, also strengthened invigorate the spleen and benefit qi, health care that blood sugar was shown and reduced to tonifying lung admittedly.
To achieve these goals, the present invention has adopted following technical scheme:
Propolis Radix Astragali soft capsule, the weight proportion of its filler component are Astragalus Root P.E 15-20%, propolis extract 13-15%, soybean oil 62-65%, beeswax 4-5%; The weight proportion of its softgel shell component is gelatin 40-43%, purified water 35-40%, glycerine 18-23% and Brown Ferric Oxide 0.5-0.7%.
Propolis Radix Astragali soft capsule, the weight proportion of its filler component are Astragalus Root P.E 18%, propolis extract 14%, soybean oil 63.5%, beeswax 4.5%; The weight proportion of its softgel shell component is gelatin 41.4%, purified water 37.3%, glycerine 20.7% and Brown Ferric Oxide 0.6%.
Propolis ganoderma lucidum preparation of soft capsule method may further comprise the steps:
(1) propolis Radix Astragali soft capsule filler preparation:
A: assort up-to-standard Astragalus Root P.E, propolis extract, soybean oil and beeswax by the prescription requirement, change in the clean area after checking, remove external packing;
B: Astragalus Root P.E, propolis extract are crossed 100 mesh sieves respectively, and standby, propolis extract faces with facing with preceding deepfreeze and sieves;
C: the soybean oil of getting weight proportion drops into blend tank, adds the beeswax of weight proportion again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling gets the mixing oil plant;
D: the propolis extract after will sieving, Astragalus Root P.E drop into to mix in the oil plant and mix, and incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumizes then, and vacuum 0.06～0.08Mpa removes bubble, gets the soft capsule filler, and is standby.
(2) propolis Radix Astragali soft capsule shell preparation:
The preparation of propolis Radix Astragali soft capsule shell glue: in the purified water of weight proportion, glycerine, Brown Ferric Oxide, gelatin input glue jar successively; Heat temperature raising to 70～80 ℃ are incubated 30 minutes while stirring; Treat gelatin all after the fusing, vacuumize and remove bubble in the glue (vacuum 0.06～0.08Mpa) is crossed 80 eye mesh screen plastic emittings, and 50～60 ℃ of insulations are standby.
(3) propolis Radix Astragali preparation of soft capsule:
A: under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the filler of step (1) propolis Radix Astragali soft capsule and the glue of step (2) propolis Radix Astragali soft capsule shell are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
B: the capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
C: the dried capsule and pill of finalizing the design is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, defective works such as bubble or leakage of oil ball are arranged;
D: qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
Beneficial effect of the present invention:
Propolis Radix Astragali soft capsule of the present invention except the broad-spectrum antiseptic that has kept propolis, the Radix Astragali, anti-inflammatory and antalgic, the regeneration of promotion histocyte, antitumor, hepatic disease, treatment gastric ulcer, mouth disease, anti-ageing, anti-stress, step-down, reduction triglyceride, cholesterol, insomnia and the antidotal effect, also strengthened invigorate the spleen and benefit qi, health care that blood sugar was shown and reduced to tonifying lung admittedly.
The specific embodiment
Embodiment 1: propolis Radix Astragali soft capsule, the weight proportion of its filler component are Astragalus Root P.E 18%, propolis extract 14%, soybean oil 63.5%, beeswax 4.5%; The weight proportion of its softgel shell component is gelatin 41.4%, purified water 37.3%, glycerine 20.7% and Brown Ferric Oxide 0.6%.
Propolis ganoderma lucidum preparation of soft capsule method may further comprise the steps:
(1) propolis Radix Astragali soft capsule filler preparation:
A: assort up-to-standard Astragalus Root P.E, propolis extract, soybean oil and beeswax by the prescription requirement, change in the clean area after checking, remove external packing;
B: Astragalus Root P.E, propolis extract are crossed 100 mesh sieves respectively, and standby, propolis extract faces with facing with preceding deepfreeze and sieves;
C: the soybean oil of getting weight proportion drops into blend tank, adds the beeswax of weight proportion again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling gets the mixing oil plant;
D: the propolis extract after will sieving, Astragalus Root P.E drop into to mix in the oil plant and mix, and incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumizes then, and vacuum 0.06～0.08Mpa removes bubble, gets the soft capsule filler, and is standby.
(2) propolis Radix Astragali soft capsule shell preparation:
The preparation of propolis Radix Astragali soft capsule shell glue: in the purified water of weight proportion, glycerine, Brown Ferric Oxide, gelatin input glue jar successively; Heat temperature raising to 70～80 ℃ are incubated 30 minutes while stirring; Treat gelatin all after the fusing, vacuumize and remove bubble in the glue (vacuum 0.06～0.08Mpa) is crossed 80 eye mesh screen plastic emittings, and 50～60 ℃ of insulations are standby.
(3) propolis Radix Astragali preparation of soft capsule:
A: under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the filler of step (1) propolis Radix Astragali soft capsule and the glue of step (2) propolis Radix Astragali soft capsule shell are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
B: the capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
C: the dried capsule and pill of finalizing the design is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, defective works such as bubble or leakage of oil ball are arranged;
D: qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
Typical case's use-case:
Example 1: regulate blood sugar
Certain man, 67 years old, retired class leader was the diabetic that disease is burdened with more than, the misery that enjoys disease to torment for a long time, concurrent cerebral thrombus again in 1996 is unable to leave the bed.After the Spring Festival in March, 2011, his friend has sent propolis Radix Astragali soft capsule here, and he began to take propolis Radix Astragali soft capsule only one month, just conscious normal circulation of qi and blood, and spirit takes a turn for the better.Take after two months, blood sugar also drops to 6.2 milliliters/liter by originally 15.5 milliliters/liter.Cerebral embolism sequela has also had improvement, can walk followingly.
Analyze: propolis Radix Astragali soft capsule can significantly reduce blood sugar, reduces the consumption of insulin, and can prevent and treat by the caused complication of diabetes.According to test, total effective rate about 40%.Propolis itself is a kind of natural broad-spectrum antibiotic, possesses the effect of bactericidal antiphlogistic.Diabetic's blood-sugar content height, hypoimmunity, easy concurrent inflammation, the propolis malicious anti-inflammatory of dispelling, effectively control is infected, and the diabetic takes propolis and can descend and cardiovascular and cerebrovascular complication to prevent eyesight, eliminates " three-many-one-little " symptom, improves the quality of living.
Example 2: bring high blood pressure down, blood fat
Certain Ms 62 years old, suffers from angiocardiopathy for a long time, diagnosis system is because high fat of blood is to cause angiocardiopathy, and under doctor's suggestion, this Ms takes propolis Radix Astragali soft capsule from May, 2011, after 3 months, blood fat, cholesterol, triglycerides all present downward trend, reach the normal level of human body after 6 months, and angiocardiopathy also takes an evident turn for the better, blood viscosity descends, conscious brains is clear, and the limb fiber crops disappear, and muscle power increases.This Ms says: be that king's nest board propolis Radix Astragali soft capsule has been removed my misery.
Analyze: propolis Radix Astragali soft capsule has very strong oxidation resistance, can not only be to reduce the harm of lipid peroxidation confrontation blood vessel, prevent vascular sclerosis, and can also reduce the content of triglyceride effectively, therefore, the elderly, especially hypertension, heart disease, arteriosclerotic, often take propolis Radix Astragali soft capsule, good health and a long life are quite had benifit.
Example 3: improve immunity
Certain man, the pensioner of government works in an office for a long time, lacks exercise, passive protective physical fitness is poor, frequent cold under friend's introduction, is taken from September, 2011 and to be taken the daily life 3 of king's nest board propolis Radix Astragali soft capsule every days, every month 90, physique obviously strengthens after 3 months, and on the basis that increases outdoor exercises, cold has disappeared!
Analyze: propolis Radix Astragali soft capsule can play the effect of immune adjuvant, the content of total serum protein and gamma globulin is increased, the phagocytic activity of leucocyte and macrophage strengthens, energy immune stimulatory function, play a role better,, it helps to improve the energy of antibody, and the specificity of body and non-specific immunity are improved.
Example 4: auxiliary curing respiratory disease
In the Lujiang County the People's Hospital, internal medicine director treats experiment with propolis Radix Astragali soft capsule to respiratory disease, with 10 milliliters of the soft tinctures of the 10% propolis Radix Astragali, 25 milliliters of adding distil waters, with the steam atomization inhalation treatment infection of the upper respiratory tract, having obtained efficient is curative effect more than 98%, and treatment bronchial astehma patient 87 examples have obtained the curative effect of curing 41 examples, produce effects 38 examples, effective 6 examples, invalid 2 examples.
Example 5: treatment gastric duodenal ulcer
In the Lujiang County the People's Hospital, internal medicine director tests with propolis Radix Astragali soft capsule treatment gastric duodenal ulcer, 30 patients are taken 2500mg propolis astragalus liquid every day, auxiliary curing through 15 days, wherein the patient more than 90% takes an evident turn for the better, hydrochloric acid in gastric juice is tending towards normally, and it is normal that the stomachial secretion function is also recovered.
Analyze: propolis Radix Astragali soft capsule has the effect of antibiotic, anti-inflammatory, pain relieving and promotion regeneration, propolis can form medical characteristics such as the impermeable film of a kind of acid at epidermis, therefore, be used for the treatment of gastric duodenal ulcer, have the advantages that pain relieving is fast, cure rate is high, recurrence rate is low, obtain tangible curative effect.
Claims (2)
1. propolis Radix Astragali soft capsule, it is characterized in that: the weight proportion of its filler component is Astragalus Root P.E 15-20%, propolis extract 13-15%, soybean oil 62-65%, beeswax 4-5%; The weight proportion of its softgel shell component is gelatin 40-43%, purified water 35-40%, glycerine 18-23% and Brown Ferric Oxide 0.5-0.7%;
Described propolis Radix Astragali preparation of soft capsule method may further comprise the steps:
(1) propolis Radix Astragali soft capsule filler preparation:
A: assort up-to-standard Astragalus Root P.E, propolis extract, soybean oil and beeswax by the prescription requirement, change in the clean area after checking, remove external packing;
B: Astragalus Root P.E, propolis extract are crossed 100 mesh sieves respectively, and standby, propolis extract faces with facing with preceding deepfreeze and sieves;
C: the soybean oil of getting weight proportion drops into blend tank, adds the beeswax of weight proportion again, heat temperature raising to 70～80 ℃, and fusing stirs, and cooling gets the mixing oil plant;
D: the propolis extract after will sieving, Astragalus Root P.E drop into to mix in the oil plant and mix, and incorporation time 20 minutes is ground 2～3 times after colloid mill, vacuumizes then, and vacuum 0.06～0.08Mpa removes bubble, gets the soft capsule filler, and is standby;
(2) propolis Radix Astragali soft capsule shell preparation:
The preparation of propolis Radix Astragali soft capsule shell glue: in the purified water of weight proportion, glycerine, Brown Ferric Oxide, gelatin input glue jar successively; Heat temperature raising to 70～80 ℃ are incubated 30 minutes while stirring; After treating that gelatin all melts, vacuumize and remove bubble in the glue, vacuum 0.06～0.08Mpa crosses 80 eye mesh screen plastic emittings, and 50～60 ℃ of insulations are standby;
(3) propolis Radix Astragali preparation of soft capsule:
A: under the environment of 18～26 ℃ of room temperatures, relative humidity 30～50%, the filler of step (1) propolis Radix Astragali soft capsule and the glue of step (2) propolis Radix Astragali soft capsule shell are put into respectively in the encapsulating machine, pelleting, the capsule and pill specification is the 0.5g/ grain;
B: the capsule and pill of producing came out of steamer through the supporting rolling cage type drying machine typing drying of encapsulating machine in 1～2 hour, evenly was positioned in the dry shallow bid, was temporarily stored between predry;
C: the dried capsule and pill of finalizing the design is washed ball with 95% edible ethanol, and washing the rearmounted temperature of ball is 20～25 ℃, and relative humidity is under 25%～30% environment, after dry 24～48 hours, chooses ball, rejects special-shaped ball, bubble or leakage of oil ball defective work are arranged;
D: qualified capsule and pill is sub-packed in the medicinal high-density polyethylene bottle of oral administration solid, every bottled 90, grab sample after the assay was approved, finished product vanning warehouse-in.
2. propolis Radix Astragali soft capsule according to claim 1, it is characterized in that: the weight proportion of its filler component is Astragalus Root P.E 18%, propolis extract 14%, soybean oil 63.5%, beeswax 4.5%; The weight proportion of its softgel shell component is gelatin 41.4%, purified water 37.3%, glycerine 20.7% and Brown Ferric Oxide 0.6%.
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| CN104068397B (en) * | 2014-06-12 | 2016-07-06 | 浙江海力生生物科技股份有限公司 | A kind of hepatoprotective capsule health food containing and preparation method thereof |
| CN105707568A (en) * | 2014-12-04 | 2016-06-29 | 兰州大学 | Alpha-linolenic acid soft capsule with function of auxiliarily lowering blood lipids and preparation method thereof |
| CN106361790A (en) * | 2016-08-26 | 2017-02-01 | 湖北新阳蜂业有限公司 | Bee propolis capsule and preparation method thereof |
| CN106491830A (en) * | 2016-11-15 | 2017-03-15 | 东莞自然衡健康科技有限公司 | Soft capsule of enhancing immunity and preparation method thereof |
| CN106798335A (en) * | 2017-01-10 | 2017-06-06 | 威海百合生物技术股份有限公司 | The application of medium chain triglyceride |
| CN106912863A (en) * | 2017-03-13 | 2017-07-04 | 巢氏健康生物科技股份有限公司 | A kind of new bee glue soft capsule and preparation method thereof |
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| CN109329835A (en) * | 2018-12-05 | 2019-02-15 | 天津铸源健康科技集团有限公司 | A kind of bee glue soft capsule and preparation method thereof |
| CN116159088A (en) * | 2022-10-21 | 2023-05-26 | 上海合全实业有限公司 | Propolis astragalus root and kudzuvine root soft capsule and preparation process thereof |
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| CN1431002A (en) * | 2003-01-20 | 2003-07-23 | 伍震懿 | Health care combination of propolis for reducing blood sugar and fat as well as method for mfg. its capsule |
| CN101869287A (en) * | 2009-04-23 | 2010-10-27 | 大兴安岭绿源蜂业有限公司 | Astragalus and honey soft capsule and preparation method thereof |
| CN102406836A (en) * | 2011-11-11 | 2012-04-11 | 完美（中国）有限公司 | Chinese medicine composition with auxiliary function of lowering blood sugar and preparation method of Chinese medicine composition |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1431002A (en) * | 2003-01-20 | 2003-07-23 | 伍震懿 | Health care combination of propolis for reducing blood sugar and fat as well as method for mfg. its capsule |
| CN101869287A (en) * | 2009-04-23 | 2010-10-27 | 大兴安岭绿源蜂业有限公司 | Astragalus and honey soft capsule and preparation method thereof |
| CN102406836A (en) * | 2011-11-11 | 2012-04-11 | 完美（中国）有限公司 | Chinese medicine composition with auxiliary function of lowering blood sugar and preparation method of Chinese medicine composition |
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