CN108210557B - Edible biological product for eliminating flatulence, repairing and nursing gastric mucosa - Google Patents
Edible biological product for eliminating flatulence, repairing and nursing gastric mucosa Download PDFInfo
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- CN108210557B CN108210557B CN201810122604.1A CN201810122604A CN108210557B CN 108210557 B CN108210557 B CN 108210557B CN 201810122604 A CN201810122604 A CN 201810122604A CN 108210557 B CN108210557 B CN 108210557B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/64—Insects, e.g. bees, wasps or fleas
- A61K35/644—Beeswax; Propolis; Royal jelly; Honey
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/535—Perilla (beefsteak plant)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
Abstract
An edible biological product prepared from natural Chinese medicinal materials for eliminating flatulence, repairing gastric mucosa, and caring comprises propolis supercritical extract, endothelium corneum Gigeriae Galli, radix Arnebiae, perilla seed oil, etc. as raw materials, and CO2Separating and extracting by supercritical technology, centrifuging at low temperature, and separating with membrane to obtain edible biological product. The formula and the preparation method of the invention are unique, the effectiveness and the safety are integrated, the product has good effects on the treatment of common stomach diseases, the stomach maintenance and physical therapy, and the elimination of gastrectasia, stomachache, stomach cold, dyspepsia, pantothenic acid and the like caused by stomach dysfunction, and the use effect is obvious.
Description
Technical Field
The invention belongs to the technical field of medicine preparation, relates to an edible biological product which is prepared by taking natural Chinese herbal medicines as raw materials and is used for eliminating flatulence, repairing and nursing gastric mucosa, and also relates to a preparation method of the edible biological product.
Background
The stomach is the innate root of the human body and is the largest digestive treatment place of the digestive system of the human body. The core of stomach nourishing and invigorating is to ensure the safe operation of the physiological function of gastric mucosa tissues, and the maintenance of the gastric mucosa cell tissues is the first major factor of the healthy operation of the stomach. However, for a long time, the phenomena of gastrectasia, stomachache, pantothenic acid, stomach cold, constipation, dyspepsia, bad breath and the like caused by the damage of the gastric mucosa are very common, and the phenomena become the most common phenomena of abnormal physiological functions of the stomach in people. According to statistics, the probability of the phenomenon caused by gastric mucosa injury is close to 20% in China at present; the probability of occurrence of such phenomena in the united states is close to 10%. With the rapid development of new normal economy in China in the last decade, the problems are not completely solved but are increased or decreased along with the irregular increase of diet in people, and the repeated attack of the problems becomes common symptoms affecting health. All of the factors are related to the physiological disorder of the stomach function influenced by the dietary living habits, poor sanitation and the living style of lack of movement of Chinese people, and all of the factors are actually the physiological phenomenon reaction caused by the mucosal injury caused by the metabolic disturbance of gastric mucosal histiocyte.
The stomach distension, stomach pain, pantothenic acid, stomach cold, constipation and oral peculiar smell are stomach dyspepsia caused by factors such as the reduction of the secretion function of the gastric mucosa, or stomach dyspepsia caused by the injury of the gastric mucosa, or adverse symptom reaction caused by the dysfunction of tissue cells in the stomach. Because the epidermal histiocyte in the stomach is a cell with secretion capability and is a moving histiocyte structure, the histiocyte is in peristalsis all the time, the motility of the histiocyte is not influenced by the consciousness of people, and the histiocyte is just in the peristalsis state and is difficult to recover once damaged. This is why gastric diseases are mostly chronic, i.e. the reason why healing of lesions in the gastric mucosa requires nourishment. The stomach has the function of secreting lubricating liquid, and plays a role in increasing the motion lubricating force of food; but also has the function of secreting gastric digestive juice, and plays a role in promoting digestion, decomposition and transformation of food; and has the function of preventing autolysis (preventing decomposition and digestion of self tissues) of gastric septum. The traditional medicines for treating gastric diseases or eliminating gastrectasia, stomachache, pantothenic acid, stomach cold, constipation and oral odor do not have the reparative property of mucous membrane cells, only promote gastric motility or replace gastric functions with medicines, and symptoms are temporarily relieved or eliminated after the medicines are taken, but the injury of the gastric mucosa is not effectively recovered. In medical institutions, operations and other methods are often adopted to treat serious stomach diseases, but the operations can cause the overall reduction of the digestion capacity of the stomach, and the deficiency of human nutrition and energy supplement can cause the reduction of both functions and physical ability.
At present, the medicines for treating stomach diseases at home and abroad mainly comprise chemical medicines, stomach medicines, oral preparations and injections. Wherein:
firstly, although the chemical medicine has the effect of relieving pain, the chemical medicine has no treatment and repair effect on the damage repair of the gastric mucosa of the gastrointestinal system;
② stomach drugs such as Sidalu, Weikangling, 39 Weitai, omeprazole, tin powder and the like can only obtain the function of temporarily relieving symptoms and can not solve the problem of repeated symptoms;
③ oral preparations and injections have the function of relieving symptoms, but can not completely repair the gastric mucosa injury.
In short, although the currently marketed drugs or nursing products for gastrointestinal diseases have various effects such as anti-inflammatory, antibacterial, pain relieving, stomach strengthening and the like, none of them have taken into consideration the problems of alleviating the reparative ability to the cells of the gastric mucosa tissue and maintaining the secretion ability of the cells of the gastric mucosa tissue, and the drugs or nursing products used have the problem of weakening the secretion ability of the mucosa to the stomach. Therefore, in the technical field, the development of a biological product which can effectively nourish the stomach, invigorate the stomach, improve the microenvironment of the gastric mucosa and promote the increase of the secretion of gastric mucosa cells so as to reduce the use frequency of gastric drugs, is expected for future gastric medication and nursing, and is also an important index for delaying the function aging of gastrointestinal mucosa cells.
Disclosure of Invention
The invention aims to solve the problems in the prior art, and further provides an edible biological product which is prepared from natural Chinese herbal medicines as raw materials and used for eliminating flatulence, repairing and nursing gastric mucosa, can protect the microenvironment of gastrointestinal tract parts, and has good effects on treating abdominal distension, gastrectasia, flatulence, stomachache, pantothenic acid, stomach cold, constipation, peculiar smell in oral cavity, repairing gastric mucosa injury and the like.
The preparation scheme of the edible biological product is obtained by the designer through careful summarization and development according to the traditional Chinese medicine diagnosis and treatment thought and the modern medicine experiment basis, and the edible biological product is prepared by adopting the modern biological preparation technical means on the basis of pharmacological analysis data of selected natural biological materials and practical experience and knowledge on stomach diseases and gastrointestinal nursing action. The effective medicinal components of the edible biological product are prepared from the following raw materials in parts by weight:
the method for preparing the edible biological product comprises the following process steps:
1. preparing a propolis supercritical extract: charging CO into propolis2Supercritical extraction tank, adding CO circularly2Performing supercritical extraction on the liquid at the extraction temperature of 15-30 ℃, the extraction pressure of 8-10 MPa and the extraction time of 1-2 hours to obtain a yellow propolis extract containing plant flavonoid components, wherein the percentage content of the supercritical extraction is 1-2%;
2. putting the perilla seeds into a squeezer, squeezing at normal temperature, and leaching to obtain perilla seed oil containing an alpha-linolenic acid component;
3. soaking the smashed endothelium corneum Gigeriae Galli in 60-80 deg.C perilla seed oil at a ratio of 1: 10 for 8-10 hr to obtain endothelium corneum Gigeriae Galli steep containing oil components of endothelium corneum Gigeriae Galli;
4. mechanically crushing radix Arnebiae, soaking in 50-60 deg.C Perilla seed oil at a ratio of 1: 10 for 1-2 hr, and centrifuging at low temperature to obtain transparent ruby red oil containing alkannin;
5. mixing the propolis extract, the endothelium corneum gigeriae galli immersion liquid and the lithospermum immersion liquid, dissolving in the rest perilla seed oil, removing sediments by freezing and centrifuging under the following process conditions, wherein the freezing temperature is 0-4 ℃, the centrifugal rotating speed is 3000-4000 rpm, and the time is 10-20 minutes, and separating the centrifuged liquid by a sound film separator to obtain a product liquid with the molecular weight less than 10000D;
6. packaging the product liquid into bottled products or making into soft capsule products to obtain the edible biological products.
The edible biological product prepared from the medicinal raw materials fully embodies the syndrome differentiation treatment principle of 'origin-correcting and source-clearing' and 'treatment of treating both principal and secondary aspects and shoulders' in the traditional Chinese medicine, and the pharmacological effects of the components in the formula are as follows.
The pharmacological action of propolis: the propolis extract is prepared by using CO2The propolis substance obtained by supercritical extraction process contains natural plant flavonoids as main ingredient, and the propolis flavonoids are natural broad-spectrum antibacterial agent,An antioxidant; the propolis can obviously enhance the cellular immune function and the organism immune function, has stronger bactericidal power and bacteriostatic power, plays an effective role in resisting bacteria and diminishing inflammation, and enhances the disease resistance and the self-healing power of a human body; the oxidation resistance of the propolis can effectively stabilize and remove free radicals, protect cell membranes, enhance cell activity and promote the self-secretion function of cells, and the propolis is a cleaner of honeycomb, maintains the cleanness of the honeycomb and has a clean biological effect on the gastrointestinal system of a human body.
Pharmacological action of endothelium corneum gigeriae galli: after the chicken's gizzard-membrane is orally taken by people, the secretion of gastric juice, the acidity and the digestive ability are all increased, the gastric motility function is obviously enhanced, the gastric motility period is prolonged, the peristalsis is enhanced, and the evacuation rate is also greatly accelerated; strengthen spleen and stomach, treat indigestion and fullness.
The pharmacological action of the lithospermum: promoting blood circulation, removing toxic substance, promoting eruption, removing necrotic tissue, and promoting granulation, and can be used for treating pyocutaneous disease, carbuncle, cellulitis, stagnation, heat toxin, skin rash, and spasm and pain of gastrointestinal smooth muscle.
Pharmacological action of perilla seed oil: the perilla seed oil is used as a solvent in a prescription, and the main component of the perilla seed oil is alpha-linolenic acid with the content of 50-70 percent; has antithrombotic, antiallergic, antiinflammatory, and antiaging effects.
Clinical use results show that the edible biological product has the following advantages:
the formula and the preparation method of the invention are unique, and integrate effectiveness and safety, the product is prepared from selected natural materials according to the technical requirements of biological products, and the product has the important characteristics that the product contains propolis plant flavone, endothelium corneum gigeriae galli, alkannin and alpha-linolenic acid, does not contain synthetic drugs and anaphylactic substances, is nontoxic, harmless and nonirritating to human bodies, and also has no side effect; the second important characteristic is that the product does not have irritation to gastric mucosa cells and does not have toxic and side effects on gastric tissue cell metabolism; the third characteristic is that the effective components contained in the edible biological product belong to low molecular weight and are easy to be absorbed by gastric mucosa tissues.
Secondly, the product of the invention is used as a stomach maintenance product and has the functions of nourishing the stomach, strengthening the stomach and eliminating and repairing the damage of gastric mucosa.
The product of the invention is used as a maintenance product of a gastrointestinal system, has the function of repairing the damage of the mucous membrane in the intestines and stomach, and has the physiotherapy function of relieving and eliminating gastrointestinal polyp, cyst, gastrectasia, stomachache and abdominal distension.
Fourthly, the product of the invention has better physical therapy and nursing effects on the rehabilitation of stomach diseases.
And fifthly, the product of the invention has obvious improvement effect on gastric acid, senile constipation of intestines and stomach and gastrectasia of the middle-aged and the elderly.
To show that the product of the invention can prevent abdominal discomfort or abdominal distension, gastrectasia, flatulence, stomachache, nausea, vomit, diarrhea and inappetence; repairing polyp, cyst, stomach cold, stomach ache, stomach distention and dyspepsia caused by gastrointestinal mucosa cell injury. The designer of the invention has product research in nearly ten years and repeated clinical trials, and practice and research prove that the product of the invention has very good effects on treatment of common stomach diseases, stomach maintenance and physical therapy, and elimination of gastrectasia, stomachache, stomach cold, dyspepsia and pantothenic acid caused by stomach dysfunction. The effectiveness of the product is recovered according to the restoration of gastric mucosa, the degree of abdominal distension elimination, the degree of flatulence elimination, the degree of gastric acid, the degree of stomach pain elimination, the degree of stomach distension elimination and the degree of inappetence are taken as standards, the obvious effect is taken as a standard according to the feeling of dyspepsia (abdominal distension, stomach distension, flatulence, oral peculiar smell, gastric ulcer and chronic gastritis), the preventive effect is taken as a standard according to the normal symptoms of stomach, and patients treated in the last decade are subjected to visit statistics as follows:
the statistical data is 300 people, the effective rate is 100%, and the significant efficiency is 83%.
The soft capsule prepared by the invention in 0.5 ml/granule is used for eliminating the curative effect statistics of peculiar smell in the oral cavity, abdominal distension, gastric acid, dyspepsia, gastric mucosa injury, gastrectasia, stomachache, stomach cold and the like in the period from 2010 in 01 month to 2014 in 12 months, the statistics is carried out for 300 people, and the days of the observation course is 15-45 days. The oral cavity odor eliminating powder is effective in eliminating oral cavity odor, abdominal distension, gastric acid and dyspepsia, the statistical data is totally effective for 300 people, and the effective rate reaches 100%; 30-60 granules of the product (specification: 0.5 ml/granule) are taken by people, 2 granules are taken orally on empty stomach every day; has obvious effects on eliminating abdominal distension, gastrectasia, flatulence, stomachache, gastric ulcer, chronic gastritis and gastric mucosa injury, and the average use of 90-120 products (with the specification of 0.5 ml/granule) by people, 2-4 products per day and the oral administration on empty stomach; 250 people have no abnormality, and the effect reaches more than 83 percent.
Detailed Description
Example one
The raw materials of the medicinal components of the edible biological product are prepared by the following method:
supercritical extraction of propolis: charging CO into propolis2Supercritical extraction tank, adding CO circularly2The liquid is subjected to supercritical extraction at the extraction temperature of 25 ℃ and the extraction pressure of 10MPa for 1 hour to obtain 1-1.5 percent of natural propolis supercritical extract which does not contain heavy metals and has yellow and bright color and luster and contains plant flavonoid components.
Purple perilla seed oil: loading fructus Perillae into a squeezer, squeezing at room temperature, and leaching to obtain fructus Perillae oil containing alpha-linolenic acid.
Chicken's gizzard-membrane immersion liquid: soaking 500g of smashed endothelium corneum Gigeriae Galli in 5000g of the above 60-80 deg.C Perilla seed oil, keeping the temperature for 8 hours, and centrifuging at low temperature to obtain endothelium corneum Gigeriae Galli steep containing oil components of endothelium corneum Gigeriae Galli.
Soaking radix arnebiae in liquid: mechanically crushing 100g radix Arnebiae, soaking in 5000g of above Perilla seed oil, keeping the temperature at 50 deg.C for 2 hr, and centrifuging at low temperature to obtain transparent oily red gem-red radix Arnebiae steep containing alkannin.
(II) preparing raw materials according to the following proportion:
(III) the production method comprises the following steps:
1. dissolving the propolis extract, the endothelium corneum Gigeriae Galli extract and the radix Arnebiae extract in 5kg of Perilla seed oil, respectively, freezing and centrifuging at 0-4 deg.C and 3000-4000 rpm for 20 min to remove precipitate, separating the centrifugate with an acoustic membrane separator, removing residue, and keeping supernatant to obtain medicinal liquid with molecular weight less than 10000D.
2. And (4) subpackaging the separated liquid into soft capsules or subpackaging into bottles to obtain the finished product.
The effective rate of the formula on oral peculiar smell, abdominal distension, gastric acid and dyspepsia is up to 100%.
Example two
The raw materials of the medicinal components of the edible biological product are prepared by the following method:
supercritical extraction of propolis: charging CO into propolis2Supercritical extraction tank, adding CO circularly2The liquid is subjected to supercritical extraction at the extraction temperature of 25 ℃ and the extraction pressure of 10MPa for 1 hour to obtain 1-1.5 percent of natural propolis supercritical extract which does not contain heavy metals and has yellow and bright color and luster and contains plant flavonoid components.
Purple perilla seed oil: loading fructus Perillae into a squeezer, squeezing at room temperature, and leaching to obtain fructus Perillae oil containing alpha-linolenic acid.
Chicken's gizzard-membrane immersion liquid: soaking 300g of smashed endothelium corneum Gigeriae Galli in 5000g of the above 60-80 deg.C Perilla seed oil, keeping the temperature for 6 hours, and centrifuging at low temperature to obtain endothelium corneum Gigeriae Galli steep containing oil components of endothelium corneum Gigeriae Galli.
Soaking radix arnebiae in liquid: mechanically crushing 300g of radix Arnebiae, soaking in 5000g of above Perilla seed oil, keeping the temperature at 50 deg.C for 2 hr, and centrifuging at low temperature to obtain transparent oily radix Arnebiae extract containing alkannin.
(II) preparing raw materials according to the following proportion:
(III) the production method comprises the following steps:
1. dissolving the propolis extract, the endothelium corneum Gigeriae Galli extract and the radix Arnebiae extract in 5kg of Perilla seed oil, respectively, freezing and centrifuging at 0-4 deg.C and 3000-4000 rpm for 20 min to remove precipitate, separating the centrifugate with an acoustic membrane separator, removing residue, and keeping supernatant to obtain medicinal liquid with molecular weight less than 10000D.
2. And (4) subpackaging the separated liquid into soft capsules or subpackaging into bottles to obtain the finished product.
The formula has high obvious effect (up to 83%) on abdominal distension, gastrectasia, flatulence, stomachache, gastric ulcer, chronic gastritis and gastric mucosa injury.
EXAMPLE III
The raw materials of the medicinal components of the edible biological product are prepared by the following method:
supercritical extraction of propolis: charging CO into propolis2Supercritical extraction tank, adding CO circularly2The liquid is subjected to supercritical extraction at the extraction temperature of 25 ℃ and the extraction pressure of 10MPa for 1 hour to obtain 1-1.5 percent of natural propolis supercritical extract which does not contain heavy metals and has yellow and bright color and luster and contains plant flavonoid components.
Purple perilla seed oil: loading fructus Perillae into a squeezer, squeezing at room temperature, and leaching to obtain fructus Perillae oil containing alpha-linolenic acid.
Chicken's gizzard-membrane immersion liquid: soaking 500g of smashed endothelium corneum Gigeriae Galli in 5000g of the above 60-80 deg.C Perilla seed oil, keeping the temperature for 8 hours, and centrifuging at low temperature to obtain endothelium corneum Gigeriae Galli steep containing oil components of endothelium corneum Gigeriae Galli.
Soaking radix arnebiae in liquid: mechanically crushing 500g radix Arnebiae, soaking in 5000g of above Perilla seed oil, keeping the temperature at 50 deg.C for 2 hr, and centrifuging at low temperature to obtain transparent oily red gem-red radix Arnebiae steep containing alkannin.
(II) preparing raw materials according to the following proportion:
(III) the production method comprises the following steps:
1. dissolving the propolis extract, the endothelium corneum Gigeriae Galli extract and the radix Arnebiae extract in 5kg of Perilla seed oil, respectively, freezing and centrifuging at 0-4 deg.C and 3000-4000 rpm for 20 min to remove precipitate, separating the centrifugate with an acoustic membrane separator, removing residue, and keeping supernatant to obtain medicinal liquid with molecular weight less than 10000D.
2. And (4) subpackaging the separated liquid into soft capsules or subpackaging into bottles to obtain the finished product.
The prescription has high curative effect (up to 86%) on abdominal distension, gastrectasia, flatulence, stomachache, gastric ulcer, chronic gastritis and gastric mucosa injury.
Claims (1)
1. An edible biological product for eliminating flatulence, repairing and nursing gastric mucosa is characterized in that the effective pharmaceutical ingredients of the edible biological product are prepared from the following raw materials in parts by weight:
the method for preparing the edible biological product comprises the following process steps:
1.1 preparation of propolis supercritical extract: charging CO into propolis2Supercritical extraction tank, adding CO circularly2Performing supercritical extraction on the liquid, wherein the extraction temperature is 15-30 ℃, the extraction pressure is 8-10 MPa, and the extraction time is 1-2 hours, so as to obtain 1-2% of yellow propolis extract containing plant flavonoid components;
1.2 putting the perilla seeds into a squeezer, squeezing at normal temperature, and leaching to obtain perilla seed oil containing an alpha-linolenic acid component;
1.3 soaking the smashed endothelium corneum Gigeriae Galli in perilla seed oil at the temperature of 60-80 ℃ at the ratio of 1: 10 for 8-10 hours to obtain endothelium corneum Gigeriae Galli steep containing oil components of endothelium corneum Gigeriae Galli;
1.4 mechanically crushing radix Arnebiae, soaking in 50-60 deg.C Perilla seed oil at a ratio of 1: 10 for 1-2 hr, and centrifuging at low temperature to obtain transparent ruby red oil containing alkannin;
1.5 mixing the propolis extract, the endothelium corneum gigeriae galli immersion liquid and the lithospermum immersion liquid, dissolving in the rest perilla seed oil, removing sediments through freezing and centrifuging under the following process conditions, wherein the freezing temperature is 0-4 ℃, the centrifugal speed is 3000-4000 rpm, and the time is 10-20 minutes, and separating the centrifuged liquid through an acoustic membrane separator to obtain a product liquid with the molecular weight less than 10000D;
1.6 packaging the product liquid into bottled products or making into soft capsule products to obtain the edible biological products.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101095895A (en) * | 2007-07-06 | 2008-01-02 | 韦建学 | Externally-used medicament for the sanitation and health-care of female vagina and for treating gynecology vagina diseases and method for making the same |
| CN103285174A (en) * | 2013-06-29 | 2013-09-11 | 王玉欣 | Nursing ointment for repairing scars |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101095895A (en) * | 2007-07-06 | 2008-01-02 | 韦建学 | Externally-used medicament for the sanitation and health-care of female vagina and for treating gynecology vagina diseases and method for making the same |
| CN103285174A (en) * | 2013-06-29 | 2013-09-11 | 王玉欣 | Nursing ointment for repairing scars |
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