CN102813878A - Traditional Chinese medicine composition for treating recurrence of meningiomas after surgery - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for treating recurrence of meningiomas after the surgery. The traditional Chinese medicine is characterized by comprising the following raw materials: 6-9g of frankincense, 6-8g of myrrh, 3-6g of stiff silkworm, 6-10g of salvia chinensis, 6-10g of curcuma zedoary, 3-6g of edible tulip, 6-8g of ligusticum wallichii, 6-8g of red-rooted salvia root, 4-6g of radix angelicae, 6-8g of red peony root, 4-6g of caulis spatholobi, 3-6g of sculellaria barbata, 3-6g of self heal, 4-6g of mangnolia officinalis, 4-6g of coix seed, 6-8g of codonopsis pilosula, 4-6g of angelica, 4-6g of tuckahoe, 4-6g of rhizoma alismatis and 4-6g of liquorice. The traditional Chinese medicine composition has the beneficial effects of promoting blood circulation for removing blood stasis, supporting the healthy energy, resolving hard lump and inducing diuresis to alleviate edema. The traditional Chinese medicine composition has the characteristics of good treatment effect, high remission rate, low cost and low toxic side effect. The recurrence of meningiomas is dialectically treated according to different symptom patterns in clinical science.

Description

A kind of Chinese medicine composition of treating the meningioma postoperative recurrence

Technical field

The present invention relates to a kind of Chinese medicine composition of treating the meningioma postoperative recurrence.

Background technology

As everyone knows, meningioma is according to growth position and growth characteristic, and the meningioma excision need together be cut away the meninges of periphery just and can cure completely; No longer recurrence, but can't cut functional lesion entirely for fear of the operation back for basis cranii and the meninges part of removing about 50% that cuts tough; Even for cutting art entirely, it is remaining still to have tumor at former position, so be difficult to radical cure; Relapse rate is very high, and recurrence back adopts the symptomatic treatment can only the respite symptom, and postoperative recurrence brings very big pressure for patient's body and mind.

Summary of the invention

The objective of the invention is in order to solve above-mentioned technical deficiency, good effect, remission rate height are provided, a kind of Chinese medicine composition of treating the meningioma postoperative recurrence that cost is low and toxic and side effects is few.

For realizing above-mentioned purpose; A kind of Chinese medicine composition of treating the meningioma postoperative recurrence is characterized in that the crude drug of Chinese medicine consists of: Olibanum 6～9g, Myrrha 6～8g, Bombyx Batryticatus 3～6g, Herba Salviae Chinensis 6～10g, Rhizoma Curcumae 6～10g, Pseudobulbus Cremastrae Seu Pleiones 3～6g, Rhizoma Chuanxiong 6～8g, Radix Salviae Miltiorrhizae 6～8g, the Radix Angelicae Dahuricae 4～6g, Radix Paeoniae Rubra 6～8g, Caulis Spatholobi 4～6g, Herba Scutellariae Barbatae 3～6g, Spica Prunellae 3～6g, Cortex Magnoliae Officinalis 4～6g, Semen Coicis 4～6g, Radix Codonopsis 6～8g, Radix Angelicae Sinensis 4～6g, Poria 4～6g, Rhizoma Alismatis 4～6g, Radix Glycyrrhizae 4～6g.

The invention has the beneficial effects as follows: blood circulation promoting and blood stasis dispelling, strengthening the body resistance, hard masses softening and resolving, inducing diuresis to remove edema.Clinical often according to different pattern of syndrome determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs.

Olibanum acrid in the mouth in the Chinese medicine of the present invention, hardship, warm in nature.Function cures mainly: regulating qi and activating blood, analgesic therapy chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge." pearl sac ": fixed all warps are pain.Modern pharmacological research, the function of Myrrha cures mainly: the blood blood stasis removing that looses, subduing swelling and relieving pain.Be not taken by pregnant women.The Bombyx Batryticatus salty in the mouth, suffering, property is flat.Return liver, lung, stomach warp.Xifeng antispasmodic, carminative Tongluozhitong, phlegm, effective against brain tumors.Herba Salviae Chinensis, acrid in the mouth, hardship, cold nature.Function cures mainly: blood circulation promoting and blood stasis dispelling, clearing away heat-damp and promoting diuresis, mass dissipating and swelling eliminating.Rhizoma Curcumae acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Function cures mainly: the removing blood stasis promoting the circulation of QI to relieve pain.Modern study, antitumor, antibiotic, leukocyte increasing ...Pseudobulbus Cremastrae Seu Pleiones sweet in the mouth, little suffering, cool in nature.Return liver, spleen channel.Function cures mainly: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses.Be used for the carbuncle furunculosis, the scrofula sucutaneous nodule.The Rhizoma Chuanxiong acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.Be used to pacify nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.The Radix Salviae Miltiorrhizae bitter in the mouth is slightly cold.GUIXIN, Liver Channel.Function cures mainly: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind." detailed outline ": main osteodynia, strong wind, carbuncle.The Radix Angelicae Dahuricae is warm in nature, acrid in the mouth.Function cures mainly: wind-damp dispelling, the evacuation of pus of invigorating blood circulation, granulation promoting pain relieving.Be used for headache, toothache, nasal sinusitis.Modern study, spasmolysis: contained bergapton, xanthotoxin, isoimperatorin second have tangible spasmolysis to the rabbit ileum.The Radix Paeoniae Rubra bitter in the mouth, cold nature.Return Liver Channel.Function cures mainly: clearing away heat and cooling blood, eliminating stasis to stop pain.Modern study has analgesia, calmness, spasmolytic, anti-thrombosis function.Caulis Spatholobi bitter in the mouth, sweet, warm in nature.Return liver, kidney channel.Function cures mainly: enrich blood, invigorate blood circulation, collateral dredging.Be used for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Modern pharmacological research has and expands blood vessel, antiplatelet aggregation, anticancer effect.Decoction pieces is newly joined ": blood stasis removing blood, tissue regeneration promoting blood, fluent passages through which vital energy circulates.Control summer filthy infection, wind arthralgia due to stagnation of blood disease.Herba Scutellariae Barbatae acrid in the mouth, hardship, cold.Return lung, liver, kidney channel.Function cures mainly: heat-clearing and toxic substances removing, blood stasis dispelling diuresis.Spica Prunellae bitter in the mouth, suffering, cold in nature.Function cures mainly: liver heat removing, eliminating stagnation, diuresis.Cortex Magnoliae Officinalis bitter in the mouth, property suffering, warm in nature.Function cures mainly: the circulation of qi promoting removing food stagnancy; Dampness is removed full; Lowering the adverse QI to relieve asthma.Semen Coicis property slightly sweet flavor is slightly cold, and effects such as inducing diuresis to remove edema, spleen invigorating are dried, arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus are arranged.Radix Codonopsis has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Modern study, Radix Codonopsis contain various saccharides, phenols, sterol, volatile oil, scutellarein glucosid, Saponin and micro-alkaloid, have effects such as enhancing immunity, blood vessel dilating, blood pressure lowering, microcirculation improvement, enhancing hemopoietic function.Radix Angelicae Sinensis sweet in the mouth, suffering.Return liver, the heart, spleen channel.Function cures mainly to enrich blood and invigorates blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Modern study.The effect of enhance immunity, anti-antithrombotic, inhibition nervus centralis is arranged.Poria sweet in the mouth, light, property are flat, be used as medicine have promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria ability enhancing human body immunity function, pachyman has tangible antitumor and protects the liver dirty effect.The Rhizoma Alismatis sweet in the mouth; Light; Cold in nature.Effect cures mainly: promoting diuresis to eliminate damp pathogen; It is treating stranguria to expel the heat-evil.Radix Glycyrrhizae property is flat, sweet in the mouth, returns 12 warps.Effect cures mainly: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.More than all medicines match, treatment should disease, brings out the best in each other.

The present invention follows the prescription principle of medication of the traditional Chinese medical science, is decocted in water for oral dose.The present invention is through clinical verification: remission rate is more than 70%, and toxic and side effects is few.

The specific embodiment

Below in conjunction with implementing case the present invention is further described:

Embodiment 1: a kind of Chinese medicine composition of treating the meningioma postoperative recurrence is characterized in that the crude drug of Chinese medicine consists of: Olibanum 6～9g, Myrrha 6～8g, Bombyx Batryticatus 3～6g, Herba Salviae Chinensis 6～10g, Rhizoma Curcumae 6～10g, Pseudobulbus Cremastrae Seu Pleiones 3～6g, Rhizoma Chuanxiong 6～8g, Radix Salviae Miltiorrhizae 6～8g, the Radix Angelicae Dahuricae 4～6g, Radix Paeoniae Rubra 6～8g, Caulis Spatholobi 4～6g, Herba Scutellariae Barbatae 3～6g, Spica Prunellae 3～6g, Cortex Magnoliae Officinalis 4～6g, Semen Coicis 4～6g, Radix Codonopsis 6～8g, Radix Angelicae Sinensis 4～6g, Poria 4～6g, Rhizoma Alismatis 4～6g, Radix Glycyrrhizae 4～6g.

Embodiment 2: a kind of Chinese medicine composition of treating the meningioma postoperative recurrence is characterized in that the crude drug of Chinese medicine consists of: Olibanum 6g, Myrrha 6g, Bombyx Batryticatus 4g, Herba Salviae Chinensis 6g, Rhizoma Curcumae 6g, Pseudobulbus Cremastrae Seu Pleiones 4g, Rhizoma Chuanxiong 6g, Radix Salviae Miltiorrhizae 6g, Radix Angelicae Dahuricae 4g, Radix Paeoniae Rubra 6g, Caulis Spatholobi 6g, Herba Scutellariae Barbatae 4g, Spica Prunellae 4g, Cortex Magnoliae Officinalis 6g, Semen Coicis 6g, Radix Codonopsis 6g, Radix Angelicae Sinensis 4g, Poria 6g, Rhizoma Alismatis 6g, Radix Glycyrrhizae 4g.

Clinical efficacy is summed up:

One, we are extensive in clinical practice for many years, treat 62 examples, and curative effect is frequently good.

Two, diagnostic criteria: the history of operation that cerebroma is arranged; Clinical manifestation; Chronic headache, spirit change, epilepsy appear; One or both sides visual deterioration even blind, ataxia or limitation skull enclosed mass etc. is arranged during the symptoms of intracranial hypertension that particularly increases the weight of with carrying out property, considered the meningioma postoperative recurrence.Examination of ocular fundus: papilloedema or be secondary atrophy.

Three, administrated method: with adding the dense decoction of frying in shallow oil into of water after above all selection of crude drugs, the mixed soaking, every dose of 200ml, morning every day, late sub-service.

Four, efficacy evaluation:

Alleviate fully: the biochemical change complete obiteration that clinical symptoms, sign and tumor are relevant, continued for 4 weeks at least, do not have new focus therebetween and occur.

Part is alleviated: reduce above 50% with the summation of comparing all the perpendicular diameter products that can survey focus before the treatment, continued for 4 weeks at least, do not have the appearance of new focus during this period.

Invalid: clinical symptoms does not have improvement or increases the weight of.

Five, therapeutic effect: treatment by Chinese herbs primary disease 62 examples of the present invention, alleviate 48 examples, improvement 11 examples, invalid 3 examples through statistics.Total effective rate is 95.1%, and remission rate is 77.4%.This medication is imitated soon, remission rate is high, toxic and side effects is few.Taboo: anemia of pregnant woman, menorrhagia person avoid and use Rhizoma Curcumae.

Six, model case:

1, king XX, the man, 42 years old, went to a doctor in November, 2009.Main suit's meningioma postoperative 2 months, radiotherapy after 1 month 3 months, excuse pain, spirit changed for 1 week, recurrence again after the symptomatic treatment of being in hospital takes a turn for the better, imaging examination: the prompting meningioma recurs.Examination of ocular fundus: papilloedema.The patient requires to obey 20 doses in Chinese medicine of the present invention, and clinical symptoms is alleviated fully, examination of ocular fundus: papilloedema disappears.Follow up a case by regular visits to not recurrence after February.

2, high XX, the man, 62 years old, went to a doctor in June, 2010.Patient main suit's meningioma postoperative half a year, headache, 1 week of feeling of fullness in the head.Use the analgesic poor effect.Head magnetic resonance: prompting meningioma recurrence.The patient requires to obey 20 doses in Chinese medicine of the present invention, remission, and drug withdrawal 2 days continues to obey 10 doses of 1 courses of treatment, and clinical symptoms is alleviated fully.Follow up a case by regular visits to not recurrence after February.

3, Liu XX, the woman, 38 years old, went to a doctor in July, 2011.Patient main suit's meningioma postoperative 8 months through 1 course of treatment of radiotherapy, occurs preoperative symptom again, headache, dizzy companion's projectile vomiting.Have a medical check-up: cervical region is strong, lift difficulty on the right upper extremity.Imaging examination: prompting meningioma recurrence.The patient required to obey behind 20 doses in the Chinese medicine of the present invention drug withdrawal 2 days, obeyed 20 doses again, and the patient is at the menstrual phase Rhizoma Curcumae of having stopped using.Clinical symptoms is alleviated fully.Follow up a case by regular visits to not recurrence again after February.

Claims (1)

1. the present invention relates to a kind of Chinese medicine composition of treating the meningioma postoperative recurrence, it is characterized in that the crude drug of Chinese medicine consists of: Olibanum 6～9g, Myrrha 6～8g, Bombyx Batryticatus 3～6g, Herba Salviae Chinensis 6～10g, Rhizoma Curcumae 6～10g, Pseudobulbus Cremastrae Seu Pleiones 3～6g, Rhizoma Chuanxiong 6～8g, Radix Salviae Miltiorrhizae 6～8g, the Radix Angelicae Dahuricae 4～6g, Radix Paeoniae Rubra 6～8g, Caulis Spatholobi 4～6g, Herba Scutellariae Barbatae 3～6g, Spica Prunellae 3～6g, Cortex Magnoliae Officinalis 4～6g, Semen Coicis 4～6g, Radix Codonopsis 6～8g, Radix Angelicae Sinensis 4～6g, Poria 4～6g, Rhizoma Alismatis 4～6g, Radix Glycyrrhizae 4～6g.