CN102791288B - 重组的减毒细小病毒 - Google Patents

重组的减毒细小病毒 Download PDF

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Publication number
CN102791288B
CN102791288B CN201180012606.1A CN201180012606A CN102791288B CN 102791288 B CN102791288 B CN 102791288B CN 201180012606 A CN201180012606 A CN 201180012606A CN 102791288 B CN102791288 B CN 102791288B
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parvovirus
dna
recombinant
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vaccine
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CN102791288A (zh
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N.斯皮贝
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Intervet International BV
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Intervet International BV
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/23Parvoviridae, e.g. feline panleukopenia virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14311Parvovirus, e.g. minute virus of mice
    • C12N2750/14334Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011Details
    • C12N2750/14011Parvoviridae
    • C12N2750/14311Parvovirus, e.g. minute virus of mice
    • C12N2750/14361Methods of inactivation or attenuation
    • C12N2750/14362Methods of inactivation or attenuation by genetic engineering

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN201180012606.1A 2010-03-05 2011-03-03 重组的减毒细小病毒 Active CN102791288B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US31103210P 2010-03-05 2010-03-05
EP10155646.2 2010-03-05
US61/311,032 2010-03-05
US61/311032 2010-03-05
EP10155646 2010-03-05
PCT/EP2011/053164 WO2011107534A1 (en) 2010-03-05 2011-03-03 Recombinant attenuated parvovirus

Publications (2)

Publication Number Publication Date
CN102791288A CN102791288A (zh) 2012-11-21
CN102791288B true CN102791288B (zh) 2015-02-18

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CN201180012606.1A Active CN102791288B (zh) 2010-03-05 2011-03-03 重组的减毒细小病毒

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US (1) US9234182B2 (enExample)
EP (1) EP2542260B1 (enExample)
JP (3) JP6200155B2 (enExample)
CN (1) CN102791288B (enExample)
AU (1) AU2011222910B2 (enExample)
CA (1) CA2790653C (enExample)
DK (1) DK2542260T3 (enExample)
ES (1) ES2566033T3 (enExample)
RU (1) RU2527157C2 (enExample)
WO (1) WO2011107534A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2566033T3 (es) * 2010-03-05 2016-04-08 Intervet International B.V. Parvovirus recombinante atenuado
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
US20140234354A1 (en) * 2013-02-15 2014-08-21 Boehringer Ingelheim Vetmedica, Inc. Porcine parvovirus 5b, methods of use and vaccine
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
CN105263953B (zh) * 2014-01-15 2020-01-07 勃林格殷格翰动物保健美国有限公司 猪细小病毒5a、使用方法及疫苗
JP6938155B2 (ja) 2014-04-17 2021-09-22 インターベット インターナショナル ベー. フェー. ブタパルボウイルス
EA201991065A1 (ru) 2016-11-03 2019-11-29 Вакцина против свиного парвовируса
RS64144B1 (sr) 2016-11-03 2023-05-31 Boehringer Ingelheim Vetmedica Gmbh Vakcina protiv svinjskog parvovirusa i virusa reproduktivnog i respiratornog sindroma svinja i postupci njegove proizvodnje
CA3196668A1 (en) 2020-11-04 2022-05-12 Intervet International B.V. Canine parvovirus
CN114957406B (zh) * 2022-05-26 2024-02-02 吉林大学 一种犬细小病毒的三价抗原和三价病毒样颗粒以及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000028004A1 (en) * 1998-11-10 2000-05-18 The University Of North Carolina At Chapel Hill Virus vectors and methods of making and administering the same
WO2008157236A1 (en) * 2007-06-14 2008-12-24 The Board Of Regents For Oklahoma State University Vaccines containing canine parvovirus genetic variants

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8502399D0 (en) * 1985-01-31 1985-03-06 Akzo Nv Canine parvovirus vaccines
ES2357679T3 (es) * 2005-07-28 2011-04-28 Pfizer Products Inc. VACUNA CONTRA CALICIVIRUS FELINO (FCV) QUE COMPRENDE UNA PROTEINA DE CAPSIDA DE UN FCV O UNA PROTEINA DE LA CAPSIDA DE UN FCV AISLADA QUE COMPRENDE UNA SECUENCIA PROTEICA SEC ID Nº: 13 O SECUENCIAS PROTEICAS CON, AL MENOS, 95% DE IDENTIDAD CON ELLA.
ES2566033T3 (es) * 2010-03-05 2016-04-08 Intervet International B.V. Parvovirus recombinante atenuado

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000028004A1 (en) * 1998-11-10 2000-05-18 The University Of North Carolina At Chapel Hill Virus vectors and methods of making and administering the same
WO2008157236A1 (en) * 2007-06-14 2008-12-24 The Board Of Regents For Oklahoma State University Vaccines containing canine parvovirus genetic variants

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Characterization and recombination mapping of an antigenic and host range mutation of canine parvovirus;Parrish CR等;《Virology》;19860115;第148卷(第1期);摘要、图5 *
Recombination between vaccine and field strains of canine parvovirus is revealed by isolation of virus in canine and feline cell cultures;Mochizuki M等;《The journal of veterinary medical science》;20081231;第70卷(第12期);1305-1314 *

Also Published As

Publication number Publication date
DK2542260T3 (en) 2016-06-06
EP2542260A1 (en) 2013-01-09
EP2542260B1 (en) 2016-03-02
JP2016047053A (ja) 2016-04-07
JP6346143B2 (ja) 2018-06-20
BR112012021650A2 (pt) 2017-02-21
CA2790653C (en) 2019-02-19
WO2011107534A1 (en) 2011-09-09
US20120328652A1 (en) 2012-12-27
US9234182B2 (en) 2016-01-12
RU2527157C2 (ru) 2014-08-27
AU2011222910A1 (en) 2012-09-27
JP6200155B2 (ja) 2017-09-20
AU2011222910B2 (en) 2014-09-18
JP2013520977A (ja) 2013-06-10
CA2790653A1 (en) 2011-09-09
CN102791288A (zh) 2012-11-21
ES2566033T3 (es) 2016-04-08
RU2012142309A (ru) 2014-04-10
JP2018134088A (ja) 2018-08-30

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