CN102763644B - A kind of cyazofamid microemulsion and preparation method thereof - Google Patents
A kind of cyazofamid microemulsion and preparation method thereof Download PDFInfo
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- CN102763644B CN102763644B CN201210221312.6A CN201210221312A CN102763644B CN 102763644 B CN102763644 B CN 102763644B CN 201210221312 A CN201210221312 A CN 201210221312A CN 102763644 B CN102763644 B CN 102763644B
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Abstract
The invention discloses a kind of cyazofamid microemulsion and preparation method thereof, in cyazofamid microemulsion, the percentage by weight of each component is: cyazofamid 1-10%, solvent and cosolvent 5-60%, emulsifier 5-20%, stabilizing agent 1-5%, and surplus is deionized water.Its preparation method, after all being dissolved by former for cyazofamid medicine with solvent and cosolvent, is added in compounding kettle, then add certain proportion emulsifier, stabilizing agent and deionized water and fully mix, and obtains cyazofamid microemulsion after stirring.The present invention is efficient, low toxicity, environmentally friendly, person poultry safety, high to corps diseases activity.The technological process of production is simple, is easy to processing.
Description
Technical field
The present invention relates to a kind of disinfectant use in agriculture and preparation method thereof, specifically a kind of cyazofamid microemulsion and preparation method thereof.
Background technology
Cyazofamid is sulphaguanidine azoles fungicide, protective fungicide, and to downy mildew, epidemic disease, club root, damping off etc. have special efficacy.Mechanism of action is the supply that the electron transmission blocking Oomycete germ body mitochondrial cytochrome b c1 complex carrys out interfering energy, and its binding site is Mei Q1 center, with other bactericide without cross tolerance.Its height to pathogen selects activity may be because the sensitivity difference of target enzymes to medicament causes.To the plasmodiophora brassica bacteria of Oomycete fungal as downy mildew, Pseudo peronospara, phytophthora, pythium spp and Plasmodiophoromycetes, there is very high biologically active.
The formulations of pesticide such as missible oil, pulvis have played important function in China's pesticide industry development course, also very large ratio is occupied in Pesticidal products, then, these fall behind formulations defect that to have that environmental pollution is large, manufacturing cost is high etc. fatal, can not meet the demand of agricultural sustainable development.
Preparation Forms of Modern Pesticide to water baseization, ultramicronising, without efflorescence and the development of Co ntrolled release aspect, be namely the formulations of pesticide of matrix with water, as the water baseization pesticidal preparations such as suspending agent, microemulsion, aqueous emulsion replaces missible oil etc. to fall behind formulation.Wherein microemulsion is a kind of organic solvent can, less by even no, good drug efficacy, environmentally-friendly water-basedization novel pesticide formulation, also be the excellent liquid dosage form that a kind of alternative missible oil etc. falls behind formulation.In order to the public nuisance-free agricultural chemicals formulation of Development and Production green agricultural product, be conducive to the sustainable development of environmental protection and agricultural production, the water base chemical preparation of inventor to cyazofamid is developed, and then completes the present invention.
Summary of the invention
The present invention is directed to exist in prior art environmental pollution, endanger the shortcomings such as healthy and manufacturing cost is high, a kind of efficient, low toxicity, environmentally friendly, person poultry safety and easily producing and cyazofamid microemulsion of using and preparation method thereof are provided.
Technical scheme: for achieving the above object, the invention provides a kind of cyazofamid microemulsion, and each component is as follows by weight percentage: cyazofamid: 1-10%; Solvent and cosolvent: 5-60%; Emulsifier: 5-20%; Stabilizing agent: 1-5%; Surplus is deionized water.
Wherein:
Solvent and cosolvent are the mixing of one or more in dimethylbenzene, acetone, cyclohexanone, ethyl acetate, dimethyl formamide, 1-METHYLPYRROLIDONE, dimethyl sulfoxide (DMSO), diethyl phthalate, dibutyl phthalate.
Emulsifier is the mixing of one or more in alkylphenol polyoxyethylene, styryl phenol polyethenoxy ether, alkaryl phenol polyethenoxy ether phosphate, castor oil polyoxyethylene ether, alkylbenzenesulfonate, alkylphenol-polyethenoxy phosphate, disecoctylmaleate sodium sulfonate, polyol fatty acid ester and ethylene oxide adduct thereof, castor oil, lauryl sodium sulfate, potassium chloride, sodium sulphate.
Stabilizing agent is the mixing of one or more in antioxidant 264, epoxidized soybean oil, epoxidized linseed oil, epoxy fat, pentaerythrite, xylitol, pyrogallic acid.
Cyazofamid microemulsion preparation method is: after all being dissolved by former for cyazofamid medicine with solvent and cosolvent, be added in compounding kettle, then adds certain proportion emulsifier, stabilizing agent and deionized water and fully mix, and obtains cyazofamid microemulsion after stirring.
Cyazofamid microemulsion provided by the invention has the following advantages:
1, efficient, the low toxicity of cyazofamid microemulsion provided by the invention, environmentally friendly, person poultry safety, the cyazofamid microemulsion formulation not easily developed immunity to drugs.Adopt solvent and the emulsifier of low toxicity, stable performance, easily degrades, high to corps diseases activity, and environmental pollution is very little.The technological process of production is simple, and investment of production equipment expense is low, is easy to processing.
2, cyazofamid microemulsion provided by the invention carrys out alternative most organic solvent with deionized water; reduce environmental pollution; be conducive to ecological environmental protection; also greatly can reduce production cost, save a large amount of fossil resources, and adopt the solvent of low toxicity; greatly reduce organic solvent to the pollution of human body and environment and residual; avoid producing pollution, explosive and poisoning problem in production, make pesticide processing produce low poisoning, ensure the safety and health of people and animals.
3, cyazofamid microemulsion provided by the invention not only has well attachment and permeability to crop, and properties of product are stablized, and activity is higher, improves drug effect, reduces the dosage of medicament simultaneously.
4, cyazofamid microemulsion provided by the invention completely can as the desirable public nuisance-free agricultural chemicals bactericide of integrated pest control.
Accompanying drawing explanation
Fig. 1 is the process chart of preparation method of the present invention.
Embodiment
The present invention is described by following specific embodiment, but the invention is not restricted to following specific embodiment.In these embodiments, unless otherwise indicated, all percentage is all weight percentage.
Embodiment one: cyazofamid 2%, cyclohexanone 10%, 1-METHYLPYRROLIDONE 15%, enters compounding kettle after the abundant mixed dissolution of three, castor oil polyoxyethylene ether 10% is added again to compounding kettle, polyol fatty acid ester and ethylene oxide adduct 4% thereof, benzene sulfonate 4%, pyrogallic acid 2%, after abundant stirring and dissolving, deionized water complements to 100%, continues to be stirred to transparent, obtained 1% cyazofamid microemulsion.
Embodiment two: cyazofamid 5%, ethyl acetate 15%, diethyl phthalate 10%, enters compounding kettle after the abundant mixed dissolution of three, alkylphenol polyoxyethylene 2% is added again to compounding kettle, polyol fatty acid ester and ethylene oxide adduct 10% thereof, disecoctylmaleate sodium sulfonate 4%, antioxidant 264 2%, after abundant stirring and dissolving, deionized water complements to 100%, continues to be stirred to transparent, obtained 5% cyazofamid microemulsion.
Embodiment three: cyazofamid 10%, cyclohexanone 10%, dimethyl formamide 25%, enters compounding kettle after the abundant mixed dissolution of three, then adds disecoctylmaleate sodium sulfonate 13% to compounding kettle, alkaryl phenol polyethenoxy ether phosphate 6%, sodium sulphate 0.1%, after abundant stirring and dissolving, deionized water complements to 100%, continue to be stirred to transparent, obtained 10% cyazofamid microemulsion.
Cyazofamid microemulsion properties of product of the present invention are stablized, and are easy to produce storage, environmentally friendly, use safety.Prove through test, to the downy mildew of vegetables, fruit tree, epidemic disease, club root, damping off etc. all have good preventive effect, and after dispenser, the average preventive effect of 10 days is more than 90%; Safety is good, to crops without poisoning, is a kind of nuisanceless disinfectant use in agriculture be worthy of popularization.
Claims (1)
1. a cyazofamid microemulsion, its active ingredient is cyazofamid, it is characterized in that: each component by weight percentage, cyazofamid 5%, ethyl acetate 15%, diethyl phthalate 10%, enter compounding kettle after the abundant mixed dissolution of three, then add alkylphenol polyoxyethylene 2% to compounding kettle, polyol fatty acid ester and ethylene oxide adduct 10% thereof, disecoctylmaleate sodium sulfonate 4%, antioxidant 264 2%, after abundant stirring and dissolving, deionized water complements to 100%, continue to be stirred to transparent, obtained 5% cyazofamid microemulsion.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201210221312.6A CN102763644B (en) | 2012-06-30 | 2012-06-30 | A kind of cyazofamid microemulsion and preparation method thereof |
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| CN201210221312.6A CN102763644B (en) | 2012-06-30 | 2012-06-30 | A kind of cyazofamid microemulsion and preparation method thereof |
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| CN102763644A CN102763644A (en) | 2012-11-07 |
| CN102763644B true CN102763644B (en) | 2016-02-10 |
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| CA2896792C (en) * | 2013-04-16 | 2021-06-15 | Upl Limited | Stabilized cyazofamid composition |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003043971A1 (en) * | 2001-11-19 | 2003-05-30 | Isagro S.P.A. | Compositions based on cupric salts, cupric salts and their use for controlling phytopathogens |
| CN101647451A (en) * | 2009-07-31 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Sterilization combination containing cyazofamid |
| CN101658177A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Complex bactericidal composition containing cyazofamid |
| CN101755799A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Cyazofamid-containing bactericidal composition |
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2012
- 2012-06-30 CN CN201210221312.6A patent/CN102763644B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003043971A1 (en) * | 2001-11-19 | 2003-05-30 | Isagro S.P.A. | Compositions based on cupric salts, cupric salts and their use for controlling phytopathogens |
| CN101658177A (en) * | 2009-07-22 | 2010-03-03 | 深圳诺普信农化股份有限公司 | Complex bactericidal composition containing cyazofamid |
| CN101647451A (en) * | 2009-07-31 | 2010-02-17 | 深圳诺普信农化股份有限公司 | Sterilization combination containing cyazofamid |
| CN101755799A (en) * | 2009-11-23 | 2010-06-30 | 陈章艳 | Cyazofamid-containing bactericidal composition |
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Effective date of registration: 20190822 Address after: 225400 West of Daiwang Road, Taixing High-tech Industrial Development Zone, Taizhou City, Jiangsu Province Patentee after: Jiangsu yuan Qing Environmental Protection Technology Co., Ltd. Address before: 516000 Guangdong province Huizhou Zhongkai hi tech Development Zone No. 24 District Patentee before: Guangdong Zhongxun Agricultural Technology Co., Ltd. |
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Effective date of registration: 20201207 Address after: Room 315, No.8 Nujiang Road, Hexi District, Tianjin 300202 Patentee after: Nantong Zhonggao (Tianjin) Intellectual Property Management Co., Ltd Address before: 225400 West of Daiwang Road, Taixing High-tech Industrial Development Zone, Taizhou City, Jiangsu Province Patentee before: Jiangsu yuan Qing Environmental Protection Technology Co.,Ltd. |
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