CN102762114A - Food product having a tongue coating-eliminating effect - Google Patents
Food product having a tongue coating-eliminating effect Download PDFInfo
- Publication number
- CN102762114A CN102762114A CN2011800088958A CN201180008895A CN102762114A CN 102762114 A CN102762114 A CN 102762114A CN 2011800088958 A CN2011800088958 A CN 2011800088958A CN 201180008895 A CN201180008895 A CN 201180008895A CN 102762114 A CN102762114 A CN 102762114A
- Authority
- CN
- China
- Prior art keywords
- catechin
- test
- tongue fur
- chewing gum
- picked
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000000694 effects Effects 0.000 title claims abstract description 25
- 235000013305 food Nutrition 0.000 title claims abstract description 19
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims abstract description 34
- 235000005487 catechin Nutrition 0.000 claims abstract description 34
- 229950001002 cianidanol Drugs 0.000 claims abstract description 33
- 229940112822 chewing gum Drugs 0.000 claims abstract description 29
- 235000015218 chewing gum Nutrition 0.000 claims abstract description 29
- XMOCLSLCDHWDHP-IUODEOHRSA-N epi-Gallocatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-IUODEOHRSA-N 0.000 claims abstract description 16
- XMOCLSLCDHWDHP-UHFFFAOYSA-N L-Epigallocatechin Natural products OC1CC2=C(O)C=C(O)C=C2OC1C1=CC(O)=C(O)C(O)=C1 XMOCLSLCDHWDHP-UHFFFAOYSA-N 0.000 claims abstract description 8
- DZYNKLUGCOSVKS-UHFFFAOYSA-N epigallocatechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3cc(O)c(O)c(O)c3 DZYNKLUGCOSVKS-UHFFFAOYSA-N 0.000 claims abstract description 8
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 claims description 30
- 150000001875 compounds Chemical class 0.000 claims description 3
- -1 catechin compound Chemical class 0.000 abstract description 3
- 230000007423 decrease Effects 0.000 abstract description 3
- 150000001765 catechin Chemical class 0.000 abstract 1
- 230000002925 chemical effect Effects 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 description 12
- WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 description 10
- 229940030275 epigallocatechin gallate Drugs 0.000 description 10
- 239000000203 mixture Substances 0.000 description 7
- 206010006326 Breath odour Diseases 0.000 description 6
- 208000032139 Halitosis Diseases 0.000 description 6
- 230000001953 sensory effect Effects 0.000 description 6
- 150000008442 polyphenolic compounds Chemical class 0.000 description 5
- 235000013824 polyphenols Nutrition 0.000 description 5
- LSDPWZHWYPCBBB-UHFFFAOYSA-N Methanethiol Chemical compound SC LSDPWZHWYPCBBB-UHFFFAOYSA-N 0.000 description 4
- 235000014220 Rhus chinensis Nutrition 0.000 description 4
- 240000003152 Rhus chinensis Species 0.000 description 4
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- LNTHITQWFMADLM-UHFFFAOYSA-N anhydrous gallic acid Natural products OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- 210000000214 mouth Anatomy 0.000 description 4
- 244000269722 Thea sinensis Species 0.000 description 3
- DNJIEGIFACGWOD-UHFFFAOYSA-N ethanethiol Chemical compound CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 3
- PFTAWBLQPZVEMU-ZFWWWQNUSA-N (+)-epicatechin Natural products C1([C@@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-ZFWWWQNUSA-N 0.000 description 2
- PFTAWBLQPZVEMU-UKRRQHHQSA-N (-)-epicatechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-UKRRQHHQSA-N 0.000 description 2
- LSHVYAFMTMFKBA-TZIWHRDSSA-N (-)-epicatechin-3-O-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=CC=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 LSHVYAFMTMFKBA-TZIWHRDSSA-N 0.000 description 2
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 2
- QMMFVYPAHWMCMS-UHFFFAOYSA-N Dimethyl sulfide Chemical compound CSC QMMFVYPAHWMCMS-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- 239000004365 Protease Substances 0.000 description 2
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 2
- 238000004587 chromatography analysis Methods 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 235000021185 dessert Nutrition 0.000 description 2
- LPTRNLNOHUVQMS-UHFFFAOYSA-N epicatechin Natural products Cc1cc(O)cc2OC(C(O)Cc12)c1ccc(O)c(O)c1 LPTRNLNOHUVQMS-UHFFFAOYSA-N 0.000 description 2
- 235000012734 epicatechin Nutrition 0.000 description 2
- 229940074391 gallic acid Drugs 0.000 description 2
- 235000004515 gallic acid Nutrition 0.000 description 2
- 235000009569 green tea Nutrition 0.000 description 2
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000006558 Dental Calculus Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 206010035669 Pneumonia aspiration Diseases 0.000 description 1
- 206010065954 Stubbornness Diseases 0.000 description 1
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 1
- 230000035508 accumulation Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 201000009807 aspiration pneumonia Diseases 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 125000000837 carbohydrate group Chemical group 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 235000020965 cold beverage Nutrition 0.000 description 1
- 235000019543 dairy drink Nutrition 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 235000019564 dysgeusia Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- YLRFCQOZQXIBAB-RBZZARIASA-N fluoxymesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1CC[C@](C)(O)[C@@]1(C)C[C@@H]2O YLRFCQOZQXIBAB-RBZZARIASA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 150000003464 sulfur compounds Chemical class 0.000 description 1
- 235000013616 tea Nutrition 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 1
- 239000000811 xylitol Substances 0.000 description 1
- 229960002675 xylitol Drugs 0.000 description 1
- 235000010447 xylitol Nutrition 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G4/00—Chewing gum
- A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
- A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/84—Flavour masking or reducing agents
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/88—Taste or flavour enhancing agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
Abstract
It was discovered that the consumption of a food product which includes catechins results in a remarkable decrease in tongue coating due to chemical effects. Therefore, a food product comprising a catechin compound which has a tongue coating-eliminating effect is provided. One embodiment of said product is a chewing gum which comprises epigallocatechin
Description
Technical field
Relate to and have the food that tongue fur is removed action effect.
Background technology
Attached to the white tongue shape thing on the tongue on tongue fur.Accumulations such as tongue fur is a swill, the epithelium that comes off, bacterium and blood cell, be the material of tongue shape.Accumulating of known tongue fur is reason, the dysgeusia of halitosis, the reason of aspiration pneumonia, and in addition, the excessive tongue fur of accumulating gives other people with antihygienic sensation, hopes to be removed.
Up to now, be to remove as the method for removing tongue fur with physics always.Physics is removed the method that brushes away tongue fur through toothbrush, tongue brush etc. that is.But physics is removed the tissue on damage tongue surface when removing sometimes, in addition, can not fully remove the tongue fur that stubbornness is adhered to.
On the other hand, thus the composition of also attempting removing through picked-up performance tongue fur effect is removed tongue fur.Patent documentation 1 has disclosed to contain to remove as the tongue fur of active ingredient from the protease of plant uses composition.But in the patent documentation 1, that carries out in order to carry out effect to confirm relatively carries out before and after the tablet giving, and therefore, infers that the tongue fur that obtains removes that effect is not only because the chemical action that active ingredient causes, the physics that also has tablet to cause is removed effect.
The inventor finds: contain the food of catechin through picked-up, tongue fur is obviously removed because of chemical action, thereby has accomplished the present invention.Be meant C on catechin (catechin) narrow sense
15H
14O
6, the known water-soluble polyphenol that in the reel of xylophyta, contains in a large number, broadly comprise the polyphenol that becomes its derivative.In this specification, in order to make definition clear-cut, catechin is meant the catechin of narrow sense, when mentioning catechin, be meant catechin with and a series of polyphenol of derivative.Catechin is particularly behaved and is known as composition contained in the tea.Catechin is known to have catechin, nutgall catechin, epicatechin, epigallocatechin, L-Epicatechin gallate, Epigallo-catechin gallate (EGCG), nutgall catechin gallic acid ester, catechin and gallate etc.
In the patent documentation 1, except protease, also enumerated the example from the formulation of plant of catechin as active ingredient.But record shows that in fact catechin has the content that tongue fur is removed effect, does not also have the record about epigallocatechin.In addition, the present invention can obtain tangible tongue fur and remove effect through in food, containing catechin and giving continuously by spells, and such effect both be not disclosed yet and has not been hinted.
The prior art document
Patent documentation
Patent documentation 1: No. 2003/090704 communique of International Publication
Patent documentation 2: Japanese Patent Laid is opened the 2001-226245 communique
Summary of the invention
Problem is to remove tongue fur.
Picked-up contains the food of catechin as active ingredient.
Contain catechin as having the food that tongue fur is removed effect through picked-up, can remove tongue fur.
And then, shown through continuing picked-up to have catechin as having the food that tongue fur is removed the compound of effect, can obtain very tangible tongue fur and remove effect.Catechin is the composition from green tea.Because green tea is looked at by the Japanese parent deeply since ancient times, therefore not only security can ensure but also impression might as well.Therefore, be easy to accepted, also can guarantee the security of picked-up continuously by the consumer.
Description of drawings
Fig. 1: test arrangement
Fig. 2: tongue fur mark (TCS) through the time change
Fig. 3: the general volatile sulfide concentration through the time change
Fig. 4: sensory test mark (OLT) through the time change
The specific embodiment
The present invention provides and contains catechin as having the food that tongue fur is removed the compound of effect.
Food is not special to limit can give an example cold drink, dessert, frozen dessert, dairy products, drinks and meat etc., the lozenge of can also giving an example, chewing gum (chewing gum), candy, soft sweets.Obtain the fact of obvious effects when having confirmed especially among the present invention to use chewing gum as food.
Catechin is known to have catechin, nutgall catechin, epicatechin, epigallocatechin, L-Epicatechin gallate, Epigallo-catechin gallate (EGCG), nutgall catechin gallic acid ester, catechin and gallate etc.Among the present invention, especially preferably use Epigallo-catechin gallate (EGCG) (EGCg) as catechin.
Intake through catechin is 1 day 1～10 gram, more suitably is to absorb food of the present invention about 3～5 grams, absorbs continuously about 8 weeks, shows that the tongue fur of highly significant is removed effect.
Embodiment
The example of the present invention of giving an example below describes, but scope of the present invention is not limited to following example.
Material shown in the mixture table 1; Making contains epigallocatechin Epigallo-catechin gallate (EGCG) (being recited as EGCg in this specification sometimes) " test chewing gum 1 ", and " test chewing gum 2 " the conduct contrast that does not contain the epigallocatechin Epigallo-catechin gallate (EGCG).
[table 1]
The prescription of test chewing gum 1,2
Let the experimenter absorb the test chewing gum 1 and test chewing gum 2 of as above making, based on the evaluation of tongue fur amount and halitosis, the tongue fur of evaluation test chewing gum 1,2 is removed effect.The experimenter be hope to participate among more than 20 year old～more than 40 year old the men and women of test, inspection confirms to adhere in the oral cavity 24 people of tongue fur in the oral.Experimenters accept cleaning (de-sludging) in the oral cavity before 2 weeks of on-test, carry out removing of tartar and calculus dentalis.The experimenter is separated according to age and sex, be divided into 2 groups, be decided to be test chewing gum 1 picked-up group, test chewing gum 2 picked-up groups respectively.Experimenter of each group absorbs 10 of test oral cavity sugar 1 or 2,1 day (2 * 5 times) respectively, absorbs for 8 weeks.The tongue fur of chewing gum 1,2 of when on-test, after the 2nd week, the 4th week, the 6th week, the 8th week and the off-test, making an experiment in the 2nd week is removed Evaluation on effect.Have 4 people to leave in experimental period, therefore final parsing is that object carries out with 20 people.Fig. 1 illustrates the arrangement of test.
The tongue fur of test chewing gum 1,2 is removed the tongue fur amount that Evaluation on effect is observed visually through mensuration, the degree of halitosis is carried out.Conspicuousness difference test between each mensuration project is organized through the t check.In addition, in the observation group through the time change, carry out the conspicuousness difference test with 0 week through the t check.The mensuration of tongue fur amount, halitosis degree is carried out as follows.
The mensuration of tongue fur amount
By the visual observations tongue fur, the tongue fur area is divided into from 0～3 4 stages, thickness and is divided into 3 stages from 0～2, estimates the tongue fur amount.In addition, their value is multiplied each other be decided to be tongue fur mark (TCS).That is TCS=area (0～3) * thickness (0～2).
The mensuration of halitosis degree
The halitosis degree is carried out through gas chromatographic analysis and sensory test.Each mensuration is carried out as follows.
(I) gas chromatographic analysis
Concentration through the volatile sulfur compounds (hydrogen sulfide, methyl mercaptan, dimethyl sulphide) that contains in the gas in the gas Chromatographic Determination oral cavity.The total of hydrogen sulfide, methyl mercaptan, dimethyl sulphide concentration is designated as general volatile sulfide concentration (total VSC).
(II) sensory test
By a plurality of inspectors the breath that the experimenter breathes out in the pouch was estimated according to 0～5 6 stages, as sensory test mark (OLT).The metewand in 0～5 stage is as follows.
0: perception is less than the stink more than the odor threshold
1:, can not regard as stench though perceive the above stink of odor threshold.
2: the stink that can regard as stench
3: can be judged to be stench easily
4: sustainable fetor
5: insupportable fetor
Above result of the test is as follows.Tongue fur mark (TCS) through the time change and to be shown in Fig. 2.Transverse axis is represented all numbers after on-test, the longitudinal axis represent since 0 week TCS change on average.
In the test chewing gum 1 picked-up group,, compare with the 0th week and to see significant TCS descend (p < 0.05) in the 4th, 10 weeks.In addition,, compare, see significant minimizing (p < 0.01) with the 0th week in the 6th, 8 weeks.In addition, compare, seeing significant minimizing (p＜0.01) the 4th, 6,8,10 weeks in the test chewing gum 1 picked-up group with test chewing gum 2 picked-up groups.In addition, demonstrate during the giving of chewing gum and promptly slowly reduce,, can obtain significant effect through continuing picked-up by spells from 0～8 all tongue furs.
The general volatile sulfide concentration through the time change and to be shown in Fig. 3.Transverse axis is represented all numbers after on-test, and the longitudinal axis is represented since average (ppm) of the general volatile sulfide concentration variation of 0 week.
In the test chewing gum 1 picked-up group,, compare with the 0th week and to see significant decline (p < 0.01) in the 4th, 6,8 weeks.In addition, compare, seeing significant difference (p＜0.01) the 4th, 6,8 weeks in the test chewing gum 1 picked-up group with test chewing gum 2 picked-up groups.In addition, compare with test chewing gum 2 picked-up groups, test chewing gum 1 picked-up group is being seen significant difference (p＜0.05) the 10th week.In addition, demonstrate during the giving of chewing gum promptly from 0～8 week, value slowly reduces, and through continuing picked-up by spells, can obtain significant effect.
The sensory test mark through the time change and to be shown in Fig. 4.Transverse axis is represented all numbers after on-test, the longitudinal axis represent since 0 week sensory test mark (OLT) change on average.In the test chewing gum 1 picked-up group, compared in the 8th week and see significant decline (p < 0.05) with the 0th week.In addition, compare with test chewing gum 2 picked-up groups, test chewing gum 1 picked-up group is being seen significant difference (p＜0.01) the 6th, 8,10 weeks.In addition, demonstrate during the giving of chewing gum promptly from 0～8 week, value slowly reduces, and through continuing picked-up by spells, can obtain significant effect.
The application requires the priority based on the japanese patent application No. 2010-027685 that filed an application on February 10th, 2010, quotes the part of its content as the application.
Claims (3)
1. a food contains catechin as having the compound that tongue fur is removed effect.
2. food as claimed in claim 1, said food is chewing gum.
3. according to claim 1 or claim 2 food, catechin is an epigallocatechin.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010-027685 | 2010-02-10 | ||
| JP2010027685A JP2011160734A (en) | 2010-02-10 | 2010-02-10 | Food product having tongue plaque eliminating effect |
| PCT/JP2011/000571 WO2011099253A1 (en) | 2010-02-10 | 2011-02-02 | Food product having a tongue coating-eliminating effect |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102762114A true CN102762114A (en) | 2012-10-31 |
Family
ID=44367541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011800088958A Pending CN102762114A (en) | 2010-02-10 | 2011-02-02 | Food product having a tongue coating-eliminating effect |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2011160734A (en) |
| KR (1) | KR20120125322A (en) |
| CN (1) | CN102762114A (en) |
| TW (1) | TW201204265A (en) |
| WO (1) | WO2011099253A1 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6266891B2 (en) | 2013-03-29 | 2018-01-24 | 株式会社ロッテ | Oral cleaning composition |
| WO2022030607A1 (en) * | 2020-08-06 | 2022-02-10 | Ｎｅｘｔ Ｉｎｎｏｖａｔｉｏｎ合同会社 | Means for removing pathogenic microorganism by micellization |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03284671A (en) * | 1990-03-30 | 1991-12-16 | Suntory Ltd | Enhancement of glucosyltransferase-inhibitory activity |
| JP2001226245A (en) * | 2000-02-10 | 2001-08-21 | Hideaki Hanaki | Antimicrobial composition |
| WO2003090704A1 (en) * | 2002-04-23 | 2003-11-06 | Ezaki Glico Co., Ltd. | Foods having effect of eliminating bad breath |
| CN1868296A (en) * | 2005-05-26 | 2006-11-29 | 黄小勇 | Green tea chewing gum |
-
2010
- 2010-02-10 JP JP2010027685A patent/JP2011160734A/en active Pending
-
2011
- 2011-02-02 KR KR1020127022591A patent/KR20120125322A/en not_active Application Discontinuation
- 2011-02-02 WO PCT/JP2011/000571 patent/WO2011099253A1/en active Application Filing
- 2011-02-02 CN CN2011800088958A patent/CN102762114A/en active Pending
- 2011-02-10 TW TW100104407A patent/TW201204265A/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03284671A (en) * | 1990-03-30 | 1991-12-16 | Suntory Ltd | Enhancement of glucosyltransferase-inhibitory activity |
| JP2001226245A (en) * | 2000-02-10 | 2001-08-21 | Hideaki Hanaki | Antimicrobial composition |
| WO2003090704A1 (en) * | 2002-04-23 | 2003-11-06 | Ezaki Glico Co., Ltd. | Foods having effect of eliminating bad breath |
| CN1868296A (en) * | 2005-05-26 | 2006-11-29 | 黄小勇 | Green tea chewing gum |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20120125322A (en) | 2012-11-14 |
| JP2011160734A (en) | 2011-08-25 |
| WO2011099253A1 (en) | 2011-08-18 |
| TW201204265A (en) | 2012-02-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Balappanavar et al. | Comparison of the effectiveness of 0.5% tea, 2% neem and 0.2% chlorhexidine mouthwashes on oral health: A randomized control trial | |
| CA2631657C (en) | Chewable compositions with fast release magnolia bark extract | |
| WO2007126651A3 (en) | Breath freshening and oral cleansing products with synergistic combinations of magnolia bark extract and essential oils | |
| KR20120034656A (en) | Composition for oral cavity | |
| EP1901704A1 (en) | Breath freshening and oral cleansing product comprising a magnolia bark extract and surfactant | |
| CN106924162B (en) | Plant additive, bacteriostatic agent, oral care product and application of plant additive in preparation of oral care product | |
| Ramesh et al. | Estimation of salivary and tongue coating pH on chewing household herbal leaves: A randomized controlled trial | |
| CA2998139C (en) | Synergistic antibacterial effects of magnolia bark extract and l-arginine, n-lauroyl ethyl ester on plaque biofilm | |
| CN102762114A (en) | Food product having a tongue coating-eliminating effect | |
| CN106456485B (en) | Liquid oral composition and the method for improving its freezing restoration | |
| JP7423925B2 (en) | Growth promoter of oral bacteria and composition for oral cavity | |
| JP2010064961A (en) | Agent for adjusting normal oral bacterial flora and method for adjusting normal oral bacterial flora using the same | |
| JP2005154339A (en) | Bad breath-reducing composition | |
| JP6564084B2 (en) | Oral composition | |
| JP2015000056A (en) | Confectionery | |
| Topcuoglu et al. | Antibacterial effect of Kenger gum on mutans streptococci and its cytotoxic effect on the 3T3 fibroblast cell line. | |
| JP6631223B2 (en) | Oral antibacterial agent and oral composition | |
| JP4974709B2 (en) | Skin cosmetics | |
| JP2011160734A5 (en) | ||
| CN111050747B (en) | Dentifrice composition | |
| US20170252278A1 (en) | Inhibition of maturation of dental biofilm and cariogenic properties | |
| JP2010132564A (en) | Deodorant and oral cavity composition and food and drink including the same | |
| KR101625412B1 (en) | Composition for preventing or treating cavity and periodontal disease comprising Ambrosia trifida extract or its fraction as effective component | |
| US20210236391A1 (en) | Dental Product, use of a Dental Product and methods of use of a dental product | |
| GB2535989A (en) | Dental product, use of a dental product and methods of use of a dental product |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1176822 Country of ref document: HK |
|
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20121031 |