CN102757321B - 2,6-二甲氧基萘的生产方法 - Google Patents

2,6-二甲氧基萘的生产方法 Download PDF

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Publication number
CN102757321B
CN102757321B CN201110103310.2A CN201110103310A CN102757321B CN 102757321 B CN102757321 B CN 102757321B CN 201110103310 A CN201110103310 A CN 201110103310A CN 102757321 B CN102757321 B CN 102757321B
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dimethoxynaphthalene
dimethoxy
naphthalene
sulfate
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CN102757321A (zh
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袁仲飞
宋勇
朱志庆
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Nantong Baisheng Pharmaceutical Co.,Ltd.
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Nantong Baisheng Chemical Co Ltd
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Abstract

本发明公开了一种2，6-二甲氧基萘的生产方法，将2，6-二羟基萘溶解于丁醇溶剂中，在23%浓度的氢氧化钠存在的碱性条件下与硫酸二甲酯在35℃下反应4.2小时生成2，6-二甲氧基萘。本发明的工艺路线简单，反应条件要求低，产品得率高，其纯度高达99%以上。

Description

2,6-二甲氧基萘的生产方法
技术领域
本发明涉及一种芳香族化合物的生产方法。
背景技术
CN1724498A公开了一种2，6-二甲氧基萘的生产方法，其反应条件不能成分保证反应的高收率、高纯度。
发明内容
本发明的目的在于提供一种反应时间短，产品收率高的2，6-二甲氧基萘的生产方法。
本发明的目的技术解决方案是：
一种2，6-二甲氧基萘的生产方法，其特征是：将2，6-二羟基萘溶解于丁醇溶剂中，在23%浓度的氢氧化钠存在的碱性条件下与硫酸二甲酯在35℃下反应4.2小时生成2，6-二甲氧基萘。
2，6-二羟基萘与硫酸二甲酯的投料摩尔比为1:3.2。
本发明的工艺路线简单，反应条件要求低，产品得率高，收率90%以上，其纯度高达99%以上。
具体实施方式
下面结合实施例对本发明作进一步说明。
实施例1：
一种2，6-二甲氧基萘的生产方法，将2，6-二羟基萘溶解于丁醇溶剂中，在23%浓度的氢氧化钠存在的碱性条件下与硫酸二甲酯在35℃下反应4.2小时生成2，6-二甲氧基萘。2，6-二羟基萘与硫酸二甲酯的投料摩尔比为1:3.2。

Claims (1)

1.一种2，6-二甲氧基萘的生产方法，其特征是：将2，6-二羟基萘溶解于丁醇溶剂中，在23％浓度的氢氧化钠存在的碱性条件下与硫酸二甲酯在35℃下反应4.2小时生成2，6-二甲氧基萘；2，6-二羟基萘与硫酸二甲酯的投料摩尔比为1:3.2。
CN201110103310.2A 2011-04-25 2011-04-25 2,6-二甲氧基萘的生产方法 Active CN102757321B (zh)

Priority Applications (1)

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CN201110103310.2A CN102757321B (zh) 2011-04-25 2011-04-25 2,6-二甲氧基萘的生产方法

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CN201110103310.2A CN102757321B (zh) 2011-04-25 2011-04-25 2,6-二甲氧基萘的生产方法

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CN102757321A CN102757321A (zh) 2012-10-31
CN102757321B true CN102757321B (zh) 2015-06-17

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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022166D0 (en) * 2000-09-11 2000-10-25 F2 Chemicals Ltd Fluorination method
CN1724498A (zh) * 2004-07-20 2006-01-25 南通莱嘉利化工有限公司 2,6－二甲氧基萘的生产方法

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Address after: 226221 No.1 Shanghai Road, Binjiang fine chemical industry park, Qidong City, Nantong City, Jiangsu Province

Patentee after: Nantong Baisheng Pharmaceutical Co.,Ltd.

Address before: 226221 No.1 Shanghai Road, Binjiang fine chemical industry park, Qidong City, Nantong City, Jiangsu Province

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