CN102755504A - Chinese patent medicament for treating meningitis and preparation method thereof - Google Patents

Abstract

The invention discloses a Chinese patent medicament for treating meningitis and a preparation method thereof. The Chinese patent medicament is prepared by using astragalus root, donkey-hide gelatin, Chinese yam, stiff silkworm, root of red-rooted salvia, dioscorea nipponica makino and Sichuan lovage rhizome as raw materials. The method comprises the following steps of: soaking Chinese medicaments in warm boiled water, cleaning, and drying the Chinese medicaments for 2 to 5 hours at the temperature of between 85 and 95 DEG C under the nitrogen protection condition; sieving the mixture with a sieve of 120 meshes, soaking the obtained raw dry powder into water for 1 to 2 days in a sealed box, collecting clean solution after soaking, heating and refluxing for 3 to 4 hours by using 0.1 to 0.5 percent sesame oil, and filtering to obtain filtrate; adding ethanol into the obtained filtrate, concentrating at the temperature of between 100 and 105 DEG C to obtain paste of which the relative density is 1.1 to 1.3 (35 DEG C), and recovering the sesame oil; and drying the paste obtained by concentration, preparing powder, and filling into capsules. The Chinese patent medicament can be used for quickly treating viral meningitis and bacterial meningitis, and has a remarkable effect.

Description

Meningitic Chinese patent medicine of a kind of treatment and preparation method thereof

Technical field

The present invention relates to meningitic Chinese patent medicine of a kind of treatment and preparation method thereof, belonged to tcm field.

Background technology

Meningitis is a kind of tender and lovely meninges or the infected disease of meninges, and common complication with an antibacterial or any part of viral infection health is such as ear, hole or upper respiratory tract infection.The bacteria type meningitis is a kind of disease of especially severe, propagates through cough or sneeze, and the easiest catching a cold by germina infection needs treatment in time, if treat untimely, may be in several hours dead or cause nonvolatil hurt in spirits.The virus type meningitis is a kind of Human Immunodeficiency Viruses that can cause AIDS, though more serious most of people can recover fully, does not have sequela.Their common symptoms shows as heating, headache, vomiting and stupor etc.

At present, the treatment bacterial meningitis is through using the antibiotic of a large amount of antibacterials, being used for intravenous drip on the traditional Chinese medical science.Then need use antiviral drug for the virus type meningitis, though also there are some to treat meningitic medicine on the doctor trained in Western medicine, administration time is long, can bring the consequence of degenerative, medicine resistance to health, or therapeutic domain is not extensive.Like patent publication No. is CN101940727A; Title is " a kind of Chinese medicine preparation of treating epidemic cerebrospinal meningitis ", is that to adopt Chinese medicines such as Radix Ophiopogonis, Radix Rehmanniae, Gypsum Fibrosum be the preparation of raw material, though cooling blood for hemostasis is arranged, the effect of the relieving restlessness that clears away heart-fire; But curative effect time is long, and effect is not remarkable.Patent publication No. is CN102327364A, and title is " a kind of Chinese medicine pill of treating viral meningitis ", and the effect of heat-clearing and toxic substances removing, strengthening vital QI to eliminate pathogenic factors is arranged, but just to the meningitic treatment of virus type, can not treat the bacteria type meningitis, and therapeutic domain is narrow.These medicines all do not reach can treat bacteria type fast and can treat the meningitic purpose of virus type again, has avoided the patient owing to meningitis not of the same race is selected the worry of different medicines, simultaneously the patient is fully recovered fast.

Summary of the invention

It is long to the invention solves the foregoing invention curative effect of medication time; Effect is not remarkable; And therapeutic domain is problem widely not; Meningitic Chinese patent medicine of a kind of treatment and preparation method thereof is provided, and the present invention not only has effects such as heat-clearing and toxic substances removing, polishing consolidating superficial resistance, blood circulation promoting and enriching, and quick treatment virus type and bacteria type meningitis are had significant curative effect.

The objective of the invention is to realize through following technical scheme:

Meningitic Chinese patent medicine of said a kind of treatment and preparation method thereof is characterized in that being formed by the feedstock production of following ratio of quality and the number of copies:

Huang Shi 10-30 part, Colla Corii Asini 10-20 part, Rhizoma Dioscoreae 10-30 part,

Bombyx Batryticatus 10-30 part, Radix Salviae Miltiorrhizae 5-20 part, Rhizoma Dioscoreae Nipponicae 5-30 part,

Rhizoma Chuanxiong 5-20 part.

Optimize, meningitic Chinese patent medicine of a kind of treatment and preparation method thereof is characterized in that being formed by the feedstock production of following ratio of quality and the number of copies:

Huang Shi 15-30 part, Colla Corii Asini 15-20 part, Rhizoma Dioscoreae 10-30 part,

Bombyx Batryticatus 10-30 part, Radix Salviae Miltiorrhizae 10-20 part, Rhizoma Dioscoreae Nipponicae 10-30 part,

Rhizoma Chuanxiong 10-20 part.

Optimize, meningitic Chinese patent medicine of a kind of treatment and preparation method thereof is characterized in that being formed by the feedstock production of following ratio of quality and the number of copies again:

18 parts of Huang Shi, 18 parts in Colla Corii Asini, 20 parts of Rhizoma Dioscoreaes,

20 parts of Bombyx Batryticatus, 15 parts of Radix Salviae Miltiorrhizaes, 20 parts of Rhizoma Dioscoreae Nipponicae,

18 parts of Rhizoma Chuanxiong.

Meningitic Chinese patent medicine of said a kind of treatment and preparation method thereof is characterized in that its preparation method:

(1) soaks: get Huang Shi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae and equal to soak in the eliminating cold for resuscitation water, and use ultrasonic waves for cleaning;

(2) oven dry: other the 6 flavor medicine except the Bombyx Batryticatus is taken by weighing each raw material by the mass percent of filling a prescription, under the nitrogen protection condition, dried 2～5 hours in 85 ° of C～95 ° C;

(3) pulverize: the gained mixture is sieved through 120 orders, get raw material dry powder;

(4) cable-styled extracting: dry powder was soaked in seal box 1～2 day, is soaked the back and collect the supernatant, three times repeatedly, collect clear liquid, with 0.1～0.5% Oleum sesami reflux 3～4 hours, filter filtrating;

(5) concentrate: gained filtrating adds the Bombyx Batryticatus after grinding, and under ° C condition of 100 ° of C～105, concentrates, and being concentrated into relative density is the paste of 1.1～1.3 (35 ° of C), reclaims Oleum sesami;

(6) finished product: the paste after will concentrating is dried under the nitrogen protection condition, processes powder, incapsulates.

The inventive method and other medicines are treated the significant advantage that nephritis had: take Chinese patent medicine of the present invention after 1 week, the disease of fever, cough disappears, and conditions of patients serious after 3 weeks is basicly stable, and 4 Zhou Houke are completely recovered.

Instructions of taking: one day twice, once two (0.5mg) sent with eliminating cold for resuscitation water clothes.

The taboo item: hot, peppery excessively food was used in fasting.

The specific embodiment:

Instance 1

Huang Shi 30g Colla Corii Asini 20g Rhizoma Dioscoreae 20g

Bombyx Batryticatus 15g Radix Salviae Miltiorrhizae 5g Rhizoma Dioscoreae Nipponicae 5g

Rhizoma Chuanxiong 5g.

At first, Huang Shi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae etc. are soaked in the eliminating cold for resuscitation water, ultrasonic waves for cleaning is clean, then other the 6 flavor medicine except the Bombyx Batryticatus is taken by weighing each raw material by the mass percent of prescription; Under the nitrogen protection condition, dried 3 hours in 85 ° of C, again the gained mixture is sieved through 120 orders, get raw material dry powder, dry powder was soaked in seal box 1 day; Soak the back and collect the supernatant, three times repeatedly, collect clear liquid; With 0.3% Oleum sesami reflux 3 hours, cross and filter filtrating, again gained filtrating is added Bombyx Batryticatus; Under 103 ° of C conditions, concentrate, being concentrated into relative density is the paste of 1.1 (35 ° of C), reclaims Oleum sesami; Paste after concentrating is dried under the nitrogen protection condition, process powder, incapsulate.

Instance 2

Huang Shi 20g Colla Corii Asini 15g Rhizoma Dioscoreae 15g

Bombyx Batryticatus 20g Radix Salviae Miltiorrhizae 10g Rhizoma Dioscoreae Nipponicae 10g

Rhizoma Chuanxiong 10g.

At first, Huang Shi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae etc. are soaked in the eliminating cold for resuscitation water, ultrasonic waves for cleaning is clean, then other the 6 flavor medicine except the Bombyx Batryticatus is taken by weighing each raw material by the mass percent of prescription; Under the nitrogen protection condition, dried 4 hours in 90 ° of C, again the gained mixture is sieved through 120 orders, get raw material dry powder, dry powder was soaked in seal box 1 day; Soak the back and collect the supernatant, three times repeatedly, collect clear liquid; With 0.4% Oleum sesami reflux 3 hours, cross and filter filtrating, again gained filtrating is added Bombyx Batryticatus; Under 104 ° of C conditions, concentrate, being concentrated into relative density is the paste of 1.2 (35 ° of C), reclaims Oleum sesami; Paste after concentrating is dried under the nitrogen protection condition, process powder, incapsulate.

Instance 3

Huang Shi 18g Colla Corii Asini 12g Rhizoma Dioscoreae 15g

Bombyx Batryticatus 20g Radix Salviae Miltiorrhizae 10g Rhizoma Dioscoreae Nipponicae 15g

Rhizoma Chuanxiong 10g.

At first, Huang Shi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae etc. are soaked in the eliminating cold for resuscitation water, ultrasonic waves for cleaning is clean, then other the 6 flavor medicine except the Bombyx Batryticatus is taken by weighing each raw material by the mass percent of prescription; Under the nitrogen protection condition, dried 5 hours in 95 ° of C, again the gained mixture is sieved through 120 orders, get raw material dry powder, dry powder was soaked in seal box 2 days; Soak the back and collect the supernatant, three times repeatedly, collect clear liquid; With 0.5% Oleum sesami reflux 4 hours, cross and filter filtrating, again gained filtrating is added Bombyx Batryticatus; Under 105 ° of C conditions, concentrate, being concentrated into relative density is the paste of 1.3 (35 ° of C), reclaims Oleum sesami; Paste after concentrating is dried under the nitrogen protection condition, process powder, incapsulate.

Model case

1, Zhu, the woman, 10 years old, continue the two weeks fever and do not move back, and with cough, extension water to be had an injection and all do not had effect, is the bacteria type meningitis after diagnosing, takes capsule of the present invention after 5 days, body temperature is normal, and health is completely recovered.

2, the river so-and-so, the man, 30 years old, often feel headache and dizzy, twitch, symptoms such as vomiting are diagnosed as: the virus type meningitis, take capsule of the present invention after 1 week, the disappearance of headache and dizzy symptom, after 2 weeks, the clinical recovery from illness effect that reaches does not have recurrence so far.

3, Ma, the woman, 40 years old, sicken for consciousness, symptoms such as delirium, restless, involuntary movement appear, through being diagnosed as: meningitis, take capsule 2 of the present invention after, the state of an illness alleviates, 3 week the back physical recoveries normal, recurrence in 2 years.

Clinical effectiveness:

The present invention is through 500 meningitis patients' clinical observation, and this medicine can make and alleviate the state of an illness fast, the disease controlling development, and do not find toxic side effect, and on average took medicine for 3 weeks, be 96 % through the clinical observation obvious effective rate, more than 3 weeks of medication, can fully recover basically.

Claims (4)

1. treat meningitic Chinese patent medicine and preparation method thereof for one kind, it is characterized in that forming by the feedstock production of following ratio of quality and the number of copies:

Huang Shi 10-30 part Colla Corii Asini 10-20 part Rhizoma Dioscoreae 10-30 part

Bombyx Batryticatus 10-30 part Radix Salviae Miltiorrhizae 5-20 part Rhizoma Dioscoreae Nipponicae 5-30 part

Rhizoma Chuanxiong 5-20 part.

2. meningitic Chinese patent medicine of a kind of treatment according to claim 1 and preparation method thereof is characterized in that being formed by the feedstock production of following ratio of quality and the number of copies:

Huang Shi 15-30 part Colla Corii Asini 15-20 part Rhizoma Dioscoreae 10-30 part

Bombyx Batryticatus 10-30 part Radix Salviae Miltiorrhizae 10-20 part Rhizoma Dioscoreae Nipponicae 10-30 part

Rhizoma Chuanxiong 10-20 part.

3. meningitic Chinese patent medicine of a kind of treatment according to claim 2 and preparation method thereof is characterized in that being formed by the feedstock production of following ratio of quality and the number of copies:

20 parts of 18 portions of Rhizoma Dioscoreaes of 18 parts of Colla Corii Asini of Huang Shi

20 parts of 15 portions of Rhizoma Dioscoreae Nipponicae of 20 parts of Radix Salviae Miltiorrhizaes of Bombyx Batryticatus

18 parts of Rhizoma Chuanxiong.

4. treat meningitic Chinese patent medicine and preparation method thereof for one kind, it is characterized in that its preparation method:

(1) soaks: get Huang Shi, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae and equal to soak in the eliminating cold for resuscitation water, and use ultrasonic waves for cleaning;

(2) oven dry: other the 6 flavor medicine except the Bombyx Batryticatus is taken by weighing each raw material by the mass percent of filling a prescription, under the nitrogen protection condition, dried 2～5 hours in 85 ° of C～95 ° C;

(3) pulverize: the gained mixture is sieved through 120 orders, get raw material dry powder;

(4) cable-styled extracting: dry powder was soaked in seal box 1～2 day, is soaked the back and collect the supernatant, three times repeatedly, collect clear liquid, with 0.1～0.5% Oleum sesami reflux 3～4 hours, filter filtrating;

(5) concentrate: gained filtrating adds the Bombyx Batryticatus after grinding, and under ° C condition of 100 ° of C～105, concentrates, and being concentrated into relative density is the paste of 1.1～1.3 (35 ° of C), reclaims Oleum sesami;

(6) finished product: the paste after will concentrating is dried under the nitrogen protection condition, processes powder, incapsulates.