CN102755498A - Chinese medicine preparation for treating chronic eczema - Google Patents
Chinese medicine preparation for treating chronic eczema Download PDFInfo
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- CN102755498A CN102755498A CN2012102119834A CN201210211983A CN102755498A CN 102755498 A CN102755498 A CN 102755498A CN 2012102119834 A CN2012102119834 A CN 2012102119834A CN 201210211983 A CN201210211983 A CN 201210211983A CN 102755498 A CN102755498 A CN 102755498A
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Abstract
The invention relates to a Chinese medicine preparation for treating chronic eczema, which comprises the following bulk pharmaceutical chemicals in parts by weight: 150-200 parts of euphorbia humifusa, 25-35 parts of myrobalan fruit, 25-35 parts of fructus terminaliae billericae, 10-20 parts of scammony resin, 40-45 parts of aloe and 25-35 parts of fructus chebulae immaturus. The Chinese medicine preparation is prepared into a pharmaceutically acceptable table by adopting the steps of crushing, decocting, filtering, concentrating, granulating, tabletting and coating with a film. The Chinese medicine preparation provided by the invention is reasonable in matching, and has the effects of clearing heat and removing humidity, dispelling wind and arresting itching and nourishing Yin and moistening dryness through a medicine synergism; and clinical test results show that the Chinese medicine preparation has a remarkable treatment effect, and can be used for effectively treating symptoms of the chronic eczema.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation of treating chronic eczema, belong to medical technical field.
Background technology
Chronic eczema is the dermatosis of characteristic with pruritus, speckle, squama, infiltration, plumpness, lichenification, has repeatedly the characteristics of showing effect, being difficult to effect a radical cure.The treatment of chronic eczema needs long-term prescription, and glucocorticoid is imitated in long-term large tracts of land external by force, can cause untoward reaction such as local skin atrophy, telangiectasis, hirsutism.The tradition traditional Chinese medical science thinks that eczema is not anti-by congenital natural disposition, and lose it and take good care of the day after tomorrow, the unsuccessful or intemperance of taking food of feelings will; Give birth to heat of wetting, space between skin and muscles is not secret in addition, diseases caused by exogenous pathogenic factor wind, wet, pathogenic heat; Interior foreign minister fights, and accumulates in the natural fibre line of meat contamination skin; Send out and to be eczema, so eczema is outer by wind, wet, heat three evil invasion and attack, due to interior, the impaired depurative descending of lung QI wet by heart-fire, spleen.Show effect repeatedly or universal eczema needs of patients oral drug therapy, and, be difficult to reach the purpose of quick mitigate the disease easily to the antihistamine drug resistance.
At present, modern doctor trained in Western medicine mainly adopts antihistaminic, vitamin, hormone medicine etc. for the treatment of chronic eczema.Mostly external ointment preparation is hormones ointment, though antiinflammatory, antipruritic and reduce the effect ooze out than very fast, recurrence very soon after the drug withdrawal; Life-time service is prone to cause many untoward reaction; Increase and pigmentation like pachylosis, pore, therefore, have very big drawback as conventional medicine.
Summary of the invention
In order to solve the problems of the technologies described above, the present invention provides a kind of Chinese medicine preparation of treating chronic eczema.
The Chinese medicine preparation of treatment chronic eczema provided by the invention, process by the crude drug combination of following parts by weight:
Herba Euphorbiae Humifusae 150 ~ 200; Terminalia flesh 25 ~ 35; Fructus Terminaliae Billericae 25 ~ 35;
Scammonia resin 10 ~ 20; Aloe 40 ~ 45; FRUCTUS TERMINALIAE IMMATURUS 25 ~ 35.
As preferably, Chinese medicine preparation provided by the invention, process by the crude drug combination of following parts by weight:
Herba Euphorbiae Humifusae 180; Terminalia flesh 30; Fructus Terminaliae Billericae 30;
Scammonia resin 15; Aloe 42; FRUCTUS TERMINALIAE IMMATURUS 30.
The present invention also provides the method for preparing of above-mentioned Chinese medicine preparation, may further comprise the steps:
1) get the Scammonia resin and the Aloe pulverize separately of recipe quantity, cross 80 mesh sieves, sterilization, subsequent use;
The Herba Euphorbiae Humifusae of 2) getting recipe quantity adds 70～75% (v/v) soak with ethanol 23～25 hours of 3～5 times of amounts, heating and refluxing extraction 2～4 times, each 1～1.5 hour; Merge extractive liquid, filters filtrate recycling ethanol; Be concentrated in the time of 50 ~ 60 ℃ relative density and be 1.08～1.10 concentrated solution, subsequent use;
3) with step 2) gained medicinal residues and above-mentioned terminalia flesh, Fructus Terminaliae Billericae, FRUCTUS TERMINALIAE IMMATURUS mixing and water adding decoct 2～4 times, adds 6～10 times of amounts of water, decocted 1～1.5 hour; Filter; It is 1.08～1.10 concentrated solution that merging filtrate, filtrate decompression are concentrated in the time of 50 ~ 60 ℃ relative density, subsequent use;
4) merge two kinds of concentrated solutions, being evaporated to 50 ~ 60 ℃ of relative densities is 1.20～1.30 thick paste again, subsequent use;
5) Scammonia resin and the aloetic fine powder of getting recipe quantity mix with step 4) gained thick paste, add the microcrystalline Cellulose of 180-220 weight portion, and mixing is granulated, drying, and granulate, granule is subsequent use;
6) adding of step 5) gained granule is counted 0.4%～0.7% magnesium stearate by its weight, mix homogeneously, tabletting, bag film-coat (material is a stomach dissolution type film coating intermixture) promptly gets.
As preferably, the method for preparing of above-mentioned Chinese medicine preparation may further comprise the steps:
1) get the Scammonia resin and the Aloe pulverize separately of recipe quantity, cross sieve No. 5, sterilization, subsequent use;
The Herba Euphorbiae Humifusae of 2) getting recipe quantity adds 70% (v/v) soak with ethanol 24 hours of 4 times of amounts, heating and refluxing extraction 3 times, and each 1 hour, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated in the time of 60 ℃ relative density and is 1.08 concentrated solution, and is subsequent use;
3) with step 2) terminalia flesh, Fructus Terminaliae Billericae, the FRUCTUS TERMINALIAE IMMATURUS mixing and water adding of gained medicinal residues and above-mentioned recipe quantity decoct 3 times; Add 10 times of amounts of water for the 1st time, decocted 1 hour, the back 8 times of amounts of water that all add for 2 times decocted 1 hour; Filter; It is 1.08 concentrated solution that merging filtrate, filtrate decompression are concentrated in the time of 60 ℃ relative density, subsequent use;
4) merge two kinds of concentrated solutions, being evaporated to 60 ℃ of relative densities is 1.30 thick paste again, subsequent use;
5) get Scammonia resin and aloetic fine powder and mix with step 4) gained thick paste, add the microcrystalline Cellulose of 200 weight portions, mixing is granulated, drying, and granulate, granule is subsequent use;
6) adding of step 5) gained granule is counted 0.5% magnesium stearate by its weight, mix homogeneously is pressed into 1000, and coating (material is a stomach dissolution type film coating intermixture) promptly gets.
As preferably, the condition of concentrating under reduced pressure operation is in step 3) and the step 4) :-0.08Mpa, 80 ℃.
The present invention further provides the application of above-mentioned Chinese medicine preparation in the medicine of preparation treatment chronic eczema.
The technique effect that Chinese medicine preparation provided by the invention can be realized is:
1, the assembly of Chinese medicine preparation provided by the invention is reasonable, and its drug synergism has removing damp-heat, dispelling wind for relieving itching, nourshing Yin and drynsessmoistening prescription effect, and clinical test results shows that it is evident in efficacy, can effectively treat the symptom of chronic eczema;
2, to have dosage little for Chinese medicine preparation provided by the invention, take easy to carry, instant effect, determined curative effect, quality controllable, and safe and reliable, have no side effect and advantage that cost is low;
3, Chinese medicine preparation provided by the invention has the unusual phlegmatic temperament of elimination according to theory of Chinese medical science; Bile matter and deteriorated blood; Functions such as repellent antipruritic also can be widely used in diseases such as the treatment tinea manuum, tinea corporis, tinea pedis, tinea versicolor, psoriasis, allergic dermatitis, banded spore rash, hemorrhoid simultaneously.
The specific embodiment
Below in conjunction with specific embodiment the present invention is described further so that those skilled in the art can better understand the present invention and implementing, but the embodiment that lifts not conduct to qualification of the present invention.
The common sympton of chronic eczema has: conscious violent pruritus, skin lesion pleomorphism, erythema, pimple, papulovesicle or vesicle are intensive in flakes, are prone to ooze out indefinite border; Be dispersed in little pimple, papulovesicle on every side; Rotten to the corn, the incrustation of normal companion like secondary infection, pustule or dense crust can occur.
The middle prescription of Chinese medicine preparation provided by the invention is separated:
Herba Euphorbiae Humifusae has heat-clearing and toxic substances removing, cooling blood for hemostasis, the effect of dampness removing jaundice eliminating; Terminalia flesh has effect, the Fructus Terminaliae Billericae tool astringing intestine to stop diarrhea of " astringing the lung astringing intestine to stop diarrhea, the therapeutic method to keep the adverse QI flowing downwards " and astringes the lung the effect of pathogenic fire reducing sore-throat relieving; Scammonia resin can effectively be eliminated unusual body fluid, open raw vapour lock, and the relieving constipation diuretic is good for the stomach; The aloetic relieving constipation by purgation that act as, purging liver-fire, parasite killing is treated the effect of infantile malnutrition; FRUCTUS TERMINALIAE IMMATURUS tool clearing away heat and promoting production of body fluid, the effect of detoxifcation astringing intestine to stop diarrhea.Wherein, Herba Euphorbiae Humifusae is a monarch drug, and Scammonia resin is a ministerial drug, and Aloe, terminalia flesh and Fructus Terminaliae Billericae are adjuvant drug, and FRUCTUS TERMINALIAE IMMATURUS is a messenger drug, and all medicine combinations are used and eliminated unusual phlegmatic temperament, bile matter and deteriorated blood, effects such as repellent antipruritic.
Embodiment 1
The Chinese medicine preparation that present embodiment adopted is made up of the crude drug of following weight, unit (g):
Herba Euphorbiae Humifusae 180 g; Terminalia flesh 30 g; Fructus Terminaliae Billericae 30 g;
Scammonia resin 15 g; Aloe 42 g; FRUCTUS TERMINALIAE IMMATURUS 30 g.
Method for preparing is following:
1) get Scammonia resin and Aloe pulverize separately in the ratio in the above-mentioned prescription, cross 80 mesh sieves, sterilization, subsequent use;
2) get 70% (v/v) soak with ethanol 24 hours that Herba Euphorbiae Humifusae adds 4 times of amounts, heating and refluxing extraction 3 times, each 1 hour, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated in the time of 60 ℃ relative density and is 1.08 concentrated solution, and is subsequent use;
3) with step 2) gained medicinal residues and 30 g terminalia flesh, 30 g Fructus Terminaliae Billericaes, 30 g FRUCTUS TERMINALIAE IMMATURUS mixing and water addings decoct 3 times; Add 10 times of amounts of water for the 1st time, decocted 1 hour, the back 8 times of amounts of water that all add for 2 times decocted 1 hour; Filter; It is 1.08 concentrated solution that merging filtrate, filtrate decompression are concentrated in the time of 60 ℃ relative density, subsequent use;
4) merge two kinds of concentrated solutions, being evaporated to 60 ℃ of relative densities is 1.30 thick paste again, subsequent use;
5) get Scammonia resin and aloetic fine powder and mix with step 4) gained thick paste, add the microcrystalline Cellulose of 200 weight portions, mixing is granulated, drying, and granulate, granule is subsequent use;
6) adding of step 5) gained granule is counted 0.5% magnesium stearate by its weight; Mix homogeneously; Be pressed into 1000, (material is stomach dissolution type film coating intermixture (commercial, as to be made up of titanium dioxide, light green aluminum color lake, Pulvis Talci, polyethylene glycol 6000, hypromellose) to coating; Coating powder amount=label weight * 45%), promptly get (about 0.31g/ sheet).
Method for using: oral, every day three times, each 3 ~ 5, taking medicine before meal is used.
The below clinical efficacy and the safety of research Chinese medicine preparation treatment of the present invention chronic eczema.
Method: 62 routine patients with chronic eczema are divided into treatment group 31 example and matched group 31 examples.4 in the tablet of oral Chinese medicine preparation of the present invention is organized in treatment, 3 times/day: the oral west of matched group is for the sharp sheet 10mg of the Qin, 1 time/day.And two groups of equal external omcilon urea frost, be 2 weeks the course of treatment.
The result: treatment group cure rate is 54.84%, and effective percentage is 87.10%; The matched group cure rate is 35.49%, and effective percentage is 64.52%.Two groups of curative effect comparing differences have statistical significance, and all do not have obvious adverse reaction.Conclusion: oral Chinese medicine preparation treatment chronic eczema of the present invention has advantages such as good effect, safe ready.
Chronic eczema is the clinical common repeatability itching skin disease of department of dermatologry, and year JIUYUE is used the tablet oral medication chronic eczema of Chinese medicine preparation of the present invention in October, 2009～2010, and establishes matched group and analyze, and obtains satisfactory effect.
Physical data: this group selection 62 routine patients with chronic eczema, and its random packet is divided into treatment group and matched group, and every group of each 31 example, two groups of patients are at aspects such as age, case, sex and state of an illness symptom score, and the difference not statistically significant has comparability.1. inclusion criteria, the patients with chronic eczema of clinical definite, diagnostic criteria is " a modern skin cypridology ", at 18～60 years old age, the men and women does not limit.2. exclusion standard: erythra is local to merge serious antibacterial, virus or fungal infection person; The recent months system uses glucocorticoid, tretinoin, immunosuppressant, antifungal drug person; Be addicted to drink, gestation or the women and the women breast-feeding their children of conceived probability are arranged, diabetes, hypertension, hepatic and kidney function obstacle person are arranged.
Observation index and curative effect determinate standard: before the treatment and after 1 week of treatment and 2 weeks, the clinical symptoms of record patient and sign.Aspects such as patient's pruritus degree, target skin lesion inflammation, target skin lesion plumpness and target skin lesion area are evaluated by 5 grades of standards of grading of 0～4 minute.Main curative effect index is pruritus degree, target skin lesion inflammation, the plump degree of target skin lesion and target skin lesion area total mark improvement rate before and after changing value of treating the front and back total mark and treatment.Carry out the curative effect assessment according to the clinical improvements degree before and after the treatment.1. recovery from illness: therapeutic index>90%; 2. produce effects: therapeutic index 60～90% is 3. progressive: therapeutic index 20～60%; 4. invalid: therapeutic index < 20%.It is effective percentage that recovery from illness adds the shared percentage ratio of produce effects example number.
Therapeutic Method: the tablet (every 0.31g) of oral Chinese medicine preparation of the present invention, 3 times/day, 4/inferior are organized in treatment; Sharp Qin sheet is replaced in the oral west of matched group, each 10mg, 1 time/day.Two groups of equal external omcilon urea frost, 2 times/day, 2 weeks were 1 course of treatment.Observe the curative effect weekly before the treatment and after the treatment, and record patient clinical symptoms and sign.
Statistical procedures: The data SPSS13.0 carries out statistical analysis, and enumeration data is checked with X2, and relatively with t check, < 0.05 has significance for difference to P between group.
The result
Clinical efficacy: treatment group effective percentage 87.10%.64.52%, two group of clinical efficacy difference of matched group has statistical significance (P=0.0431), sees table 1.
Untoward reaction: occur symptom of diarrhea 16 examples (51.61%) after the treatment group is taken medicine, 3-5 days symptoms that continue to take medicine obviously disappear, and do not influence treatment.And matched group drowsiness symptom 14 examples (45.16%) occur after taking medicine, but does not influence work.The difference not statistically significant of two groups of adverse reaction rates (X2=0.2585, P=0.6111).
Chinese medicine preparation of the present invention is made up of Uygur's medical materials such as Herba Euphorbiae Humifusae, FRUCTUS TERMINALIAE IMMATURUS, Aloe, Fructus Terminaliae Billericae, Fructus Chebulae, SIKAMONIYAZHIs.Have unusual lymphatic temperament, the bile matter and the deteriorated blood of removing, rush down effects such as poison, repellent antipruritic, wide clinical application is in dermatosiss such as treatment psoriasis, seborrheic dermatitis, tinea corporis, tinea versicolor, herpes zoster, tinea manus and pedis, allergic contact dermatitis, acnes.Research recently shows; Chinese medicine preparation of the present invention can suppress the active oxygen that the macrophage respiratory burst produces; Reduce the too high cell immune response of body when emergency rating, the oxidation resistance of human body immunity improving organ or immunocyte, thereby protection body tissue cell.The tablet of Chinese medicine preparation of the present invention can also obviously suppress delayed hypersensitivity in addition, suppresses mast cell degranulation, and the pruritus reaction that histamine is caused has significant antagonism, plays antiinflammatory, antiallergic, pharmacological effect such as antipruritic.
This research shows that the treatment group adopts Chinese medicine preparation treatment chronic eczema of the present invention, clinical recovery rate 54.84%, and obvious effective rate is 32.26%, its curative effect obviously is superior to matched group.Though the untoward reaction that times of defecation increases appears in treatment group patient, after taking medicine 3～5 days, most of patients obviously disappears.In clinical practice, find simultaneously, to often with the patients with chronic eczema of the disorderly symptom of digestive tract functions such as abdominal distention and constipation, take Chinese medicine preparation treatment of the present invention after, skin lesion disappear more quickening.In a word, oral Chinese medicine preparation treatment chronic eczema of the present invention has advantages such as good effect, no obvious adverse reaction.
The table 1 liang clinical comparison of group
The above only is the preferred embodiment for proving absolutely that the present invention lifts, and protection scope of the present invention is not limited thereto.Being equal to that the technical staff in present technique field is done on basis of the present invention substitutes or conversion, all within protection scope of the present invention.Protection scope of the present invention is as the criterion with claims.
Claims (6)
1. a Chinese medicine preparation of treating chronic eczema is characterized in that, is processed by the crude drug combination of following parts by weight:
Herba Euphorbiae Humifusae 150 ~ 200; Terminalia flesh 25 ~ 35; Fructus Terminaliae Billericae 25 ~ 35;
Scammonia resin 10 ~ 20; Aloe 40 ~ 45; FRUCTUS TERMINALIAE IMMATURUS 25 ~ 35.
2. Chinese medicine preparation as claimed in claim 1 is characterized in that, is processed by the crude drug combination of following parts by weight:
Herba Euphorbiae Humifusae 180; Terminalia flesh 30; Fructus Terminaliae Billericae 30;
Scammonia resin 15; Aloe 42; FRUCTUS TERMINALIAE IMMATURUS 30.
3. the method for preparing of Chinese medicine preparation according to claim 1 is characterized in that, may further comprise the steps:
1) get the Scammonia resin and the Aloe pulverize separately of recipe quantity, cross 80 mesh sieves, sterilization, subsequent use;
The Herba Euphorbiae Humifusae of 2) getting recipe quantity adds 70～75% (v/v) soak with ethanol 23～25 hours of 3～5 times of amounts, heating and refluxing extraction 2～4 times, each 1～1.5 hour; Merge extractive liquid, filters filtrate recycling ethanol; Be concentrated in the time of 50 ~ 60 ℃ relative density and be 1.08～1.10 concentrated solution, subsequent use;
3) with step 2) terminalia flesh, Fructus Terminaliae Billericae, the FRUCTUS TERMINALIAE IMMATURUS mixing and water adding of gained medicinal residues and above-mentioned recipe quantity decoct 2～4 times, adds 6～10 times of amounts of water, decocted 1～1.5 hour; Filter; It is 1.08～1.10 concentrated solution that merging filtrate, filtrate decompression are concentrated in the time of 50 ~ 60 ℃ relative density, subsequent use;
4) merge two kinds of concentrated solutions, being evaporated to 50 ~ 60 ℃ of relative densities is 1.20～1.30 thick paste again, subsequent use;
5) get Scammonia resin and aloetic fine powder and mix with step 4) gained thick paste, add the microcrystalline Cellulose of 180-220 weight portion, mixing is granulated, drying, and granulate, granule is subsequent use;
6) adding of step 5) gained granule is counted 0.4%～0.7% magnesium stearate by its weight, mix homogeneously, tabletting, coating promptly gets.
4. like the method for preparing of the said Chinese medicine preparation of claim 3, it is characterized in that, may further comprise the steps:
1) get the Scammonia resin and the Aloe pulverize separately of recipe quantity, cross 80 mesh sieves, sterilization, subsequent use;
The Herba Euphorbiae Humifusae of 2) getting recipe quantity adds 70% (v/v) soak with ethanol 24 hours of 4 times of amounts, heating and refluxing extraction 3 times, and each 1 hour, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated in the time of 60 ℃ relative density and is 1.08 concentrated solution, and is subsequent use;
3) with step 2) terminalia flesh, Fructus Terminaliae Billericae, the FRUCTUS TERMINALIAE IMMATURUS mixing and water adding of gained medicinal residues and above-mentioned recipe quantity decoct 3 times; Add 10 times of amounts of water for the 1st time, decocted 1 hour, the back 8 times of amounts of water that all add for 2 times decocted 1 hour; Filter; It is 1.08 concentrated solution that merging filtrate, filtrate decompression are concentrated in the time of 60 ℃ relative density, subsequent use;
4) merge two kinds of concentrated solutions, being evaporated to 60 ℃ of relative densities is 1.30 thick paste again, subsequent use;
5) get Scammonia resin and aloetic fine powder and mix with step 4) gained thick paste, add the microcrystalline Cellulose of 200 weight portions, mixing is granulated, drying, and granulate, granule is subsequent use;
6) adding of step 5) gained granule is counted 5% magnesium stearate by its weight, mix homogeneously is pressed into 1000, and coating promptly gets.
5. the method for preparing of Chinese medicine preparation according to claim 1 or claim 2 is characterized in that, the condition of concentrating under reduced pressure operation is in step 3) and the step 4) :-0.08Mpa, 80 ℃.
6. the application of the described Chinese medicine preparation of claim 1 in the medicine of preparation treatment chronic eczema.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700868A (en) * | 2019-01-24 | 2019-05-03 | 依力扎提·阿布都哈克 | A kind of instant particles as Chinese medicine and preparation method thereof for treating psoriasis |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391013A (en) * | 2008-11-13 | 2009-03-25 | 陕西东泰制药有限公司 | Traditional Chinese medicine composition for treating skin disease and preparation method thereof |
-
2012
- 2012-06-26 CN CN2012102119834A patent/CN102755498A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101391013A (en) * | 2008-11-13 | 2009-03-25 | 陕西东泰制药有限公司 | Traditional Chinese medicine composition for treating skin disease and preparation method thereof |
Non-Patent Citations (7)
| Title |
|---|
| 《中华人民共和国卫生部药品标准·维吾尔药分册》 19991231 卫生部药典委员会 百癣夏塔热片 124 1-6 , * |
| 《中国皮肤性病学杂志》 20101231 陈昭;等 1%吡美莫司乳膏治疗阴囊湿疹疗效观察 1076-1077 6 第24卷, 第11期 * |
| 《中药新药与临床药理》 20031231 努尔买买提·艾买提; 等 夏塔热片合用夏塔热软膏的抗过敏作用研究 24-27 1-6 第14卷, 第1期 * |
| 努尔买买提·艾买提; 等: "夏塔热片合用夏塔热软膏的抗过敏作用研究", 《中药新药与临床药理》 * |
| 卫生部药典委员会: "《中华人民共和国卫生部药品标准·维吾尔药分册》", 31 December 1999 * |
| 王沛就；等: "百癣夏塔热片治疗慢性湿疹疗效观察", 《中国社区医师》 * |
| 陈昭;等: "1%吡美莫司乳膏治疗阴囊湿疹疗效观察", 《中国皮肤性病学杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109700868A (en) * | 2019-01-24 | 2019-05-03 | 依力扎提·阿布都哈克 | A kind of instant particles as Chinese medicine and preparation method thereof for treating psoriasis |
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Address after: 430030 Development Building, No. 607, Jianshe Avenue, Hubei, Wuhan, China Applicant after: Wuhan Jun An Pharmaceutical Co., Ltd. Address before: 430030 Development Building, No. 607, Jianshe Avenue, Hubei, Wuhan, China Applicant before: Wuhan Changjiang Julong Pharmaceutical Co.,Ltd. |
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Application publication date: 20121031 |