CN102741278A - 新化合物及其对摄食行为的作用 - Google Patents

新化合物及其对摄食行为的作用 Download PDF

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Publication number
CN102741278A
CN102741278A CN2011800075873A CN201180007587A CN102741278A CN 102741278 A CN102741278 A CN 102741278A CN 2011800075873 A CN2011800075873 A CN 2011800075873A CN 201180007587 A CN201180007587 A CN 201180007587A CN 102741278 A CN102741278 A CN 102741278A
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CN
China
Prior art keywords
xaa
pyy
pyy analogue
ala
tyr
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Pending
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CN2011800075873A
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English (en)
Chinese (zh)
Inventor
S·R·布卢姆
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Ip2ipo Innovations Ltd
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Imperial College Innovations Ltd
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Filing date
Publication date
Application filed by Imperial College Innovations Ltd filed Critical Imperial College Innovations Ltd
Publication of CN102741278A publication Critical patent/CN102741278A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G23/00—Driving gear for endless conveyors; Belt- or chain-tensioning arrangements
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57545—Neuropeptide Y
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2812/00—Indexing codes relating to the kind or type of conveyors
    • B65G2812/02—Belt or chain conveyors
    • B65G2812/02267—Conveyors having endless traction elements
    • B65G2812/02277—Common features for chain conveyors
    • B65G2812/02287—Driving means
    • B65G2812/02306—Driving drums
    • B65G2812/02316—Driving drums with means for assuring constant linear speed of chains

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
CN2011800075873A 2010-01-27 2011-01-27 新化合物及其对摄食行为的作用 Pending CN102741278A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1001333.2 2010-01-27
GBGB1001333.2A GB201001333D0 (en) 2010-01-27 2010-01-27 Novel compounds and their effects on feeding behaviour
PCT/GB2011/000110 WO2011092473A1 (en) 2010-01-27 2011-01-27 Novel compounds and their effects on feeding behaviour

Publications (1)

Publication Number Publication Date
CN102741278A true CN102741278A (zh) 2012-10-17

Family

ID=42084054

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2011800075873A Pending CN102741278A (zh) 2010-01-27 2011-01-27 新化合物及其对摄食行为的作用

Country Status (13)

Country Link
US (1) US9018160B2 (https=)
EP (1) EP2528942B1 (https=)
JP (1) JP2013518090A (https=)
KR (1) KR20120127610A (https=)
CN (1) CN102741278A (https=)
AU (1) AU2011210165B2 (https=)
BR (1) BR112012018703A2 (https=)
CA (1) CA2788013A1 (https=)
GB (1) GB201001333D0 (https=)
MX (1) MX2012008792A (https=)
RU (1) RU2012136530A (https=)
SG (1) SG182578A1 (https=)
WO (1) WO2011092473A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111727198A (zh) * 2017-12-04 2020-09-29 Ip2Ipo创新有限公司 Pyy类似物
CN114075265A (zh) * 2020-08-13 2022-02-22 丽珠医药集团股份有限公司 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂
CN114269774A (zh) * 2019-06-12 2022-04-01 Ip2Ipo创新有限公司 食欲抑制化合物

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Publication number Priority date Publication date Assignee Title
GB201101459D0 (en) 2011-01-27 2011-03-16 Imp Innovations Ltd Novel compounds and thier effects on fedding behaviour
SG11201508469YA (en) * 2013-05-02 2015-11-27 Glaxosmithkline Ip Dev Ltd Therapeutic peptides
WO2015177573A1 (en) * 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
US20170137486A1 (en) 2014-05-23 2017-05-18 Imperial Innovations Limited Peptide yy (pyy) analogues
US20170040801A1 (en) * 2015-08-04 2017-02-09 Goal Zero Llc Portable solar panel system electrical control
CN108473535A (zh) 2015-12-16 2018-08-31 饮食生活私人有限责任公司 膳食肽
JP2021512051A (ja) 2018-01-23 2021-05-13 ギラ セラピューティクス インコーポレイテッドＧｉｌａ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． ペプチドｙｙ薬学的調剤物、組成物、および方法
GB2573145A (en) * 2018-04-26 2019-10-30 Univ Ulster Peptides for metabolic disease
AU2021257477A1 (en) 2020-04-17 2022-12-08 I2O Therapeutics, Inc. Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use

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WO2005089789A2 (en) * 2004-03-17 2005-09-29 7Tm Pharma A/S Y2 selective receptor agonists for therapeutic interventions
CN1933848A (zh) * 2004-03-17 2007-03-21 7Tm制药联合股份有限公司 用于治疗性干预的y2选择性受体激动剂

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WO2005077094A2 (en) * 2004-02-11 2005-08-25 Amylin Pharmaceuticals, Inc. Pancreatic polypeptide family motifs and polypeptides comprising the same
CN101111515A (zh) * 2004-02-11 2008-01-23 艾米林制药公司 胰多肽家族基序、包含该基序的多肽和方法
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CN1933848A (zh) * 2004-03-17 2007-03-21 7Tm制药联合股份有限公司 用于治疗性干预的y2选择性受体激动剂

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111727198A (zh) * 2017-12-04 2020-09-29 Ip2Ipo创新有限公司 Pyy类似物
CN111727198B (zh) * 2017-12-04 2024-07-09 Ip2Ipo创新有限公司 Pyy类似物
CN114269774A (zh) * 2019-06-12 2022-04-01 Ip2Ipo创新有限公司 食欲抑制化合物
CN114075265A (zh) * 2020-08-13 2022-02-22 丽珠医药集团股份有限公司 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂

Also Published As

Publication number Publication date
AU2011210165A1 (en) 2012-08-23
EP2528942A1 (en) 2012-12-05
US20130023464A1 (en) 2013-01-24
WO2011092473A8 (en) 2012-08-02
KR20120127610A (ko) 2012-11-22
CA2788013A1 (en) 2011-08-04
MX2012008792A (es) 2012-11-29
AU2011210165B2 (en) 2014-06-05
BR112012018703A2 (pt) 2017-01-10
SG182578A1 (en) 2012-08-30
GB201001333D0 (en) 2010-03-17
US9018160B2 (en) 2015-04-28
RU2012136530A (ru) 2014-03-10
JP2013518090A (ja) 2013-05-20
EP2528942B1 (en) 2020-06-17
WO2011092473A1 (en) 2011-08-04

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Application publication date: 20121017