CN102727997A - Double butterfly transcranial magnetic stimulation coil - Google Patents
Double butterfly transcranial magnetic stimulation coil Download PDFInfo
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- CN102727997A CN102727997A CN2012102106073A CN201210210607A CN102727997A CN 102727997 A CN102727997 A CN 102727997A CN 2012102106073 A CN2012102106073 A CN 2012102106073A CN 201210210607 A CN201210210607 A CN 201210210607A CN 102727997 A CN102727997 A CN 102727997A
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Abstract
The invention relates to a double butterfly transcranial magnetic stimulation coil. The coil is formed by connecting a first butterfly coil and a second butterfly coil; the center of the first butterfly coil is coincided with the center of the second butterfly coil in space; two circular coils, of which the radii are Ri, of the second butterfly coil are positioned in two circular coils, of which the radii are Ro, of the corresponding first butterfly coil; and the Ro is greater than the Ri. According to the double butterfly transcranial magnetic stimulation coil, the two circular coils of which the radii are small are arranged inside the traditional butterfly coil, the spatial position of a conductor, and the radii of inner and outer coils and number of turns of the inner and outer coils are set, so that focusing degree of coil stimulation is improved; and the double butterfly transcranial magnetic stimulation coil is concentrated in stimulation range and high in pertinence, and the possibility of stimulating unrelated nervous tissues is obviously reduced.
Description
[technical field]
The invention belongs to the transcranial magnetic stimulation technical field, particularly a kind of stevedore knot structure transcranial magnetic stimulation coil.
[background technology]
Transcranial magnetic stimulation (Transcranial magnetic stimulation; Be called for short TMS) be a kind of noinvasive biostimulation technology, it utilizes time-varying magnetic field to produce induction field, causes that bioelectric current conducts in tissue; And then make nerve fiber, neuron and muscle depolarization; In order to change the action potential of cortical neurogenic cell, it is movable to influence brain intracellular metabolite and neuroelectricity, therefore can be in order to treat quite a few nerve and mental sickness.The disease that can utilize TMS to treat at present comprises that aphasia, tinnitus, Parkinson's disease, myodystonia, amyotrophic lateral sclerosis (spinal cord) lateral sclerosis, epilepsy, migraine, dysphasia, half side space are ignored, phantom pain, chronic pain, obsession etc.It can also close the activity of specific cortical area in addition, realizes the virtual property damage of brain local function.
The transcranial magnetic stimulation appearance can be divided into two parts: pulse current produces circuit and stimulating coil.The parameters of stimulating coil is the core of whole magnetic stimulating device.In order to stimulate appointed part accurately and effectively, the intensity in the magnetic field that coil is produced, stimulate the degree of depth and degree of focus all to propose very high requirement.On the other hand, from the angle of studying physiological effect, also need accurately to quantize the parameters of coil.The degree of focus that magnetic stimulates has determined the stimulation selective power of magnetic stimulator.High degree of focus can be dwindled field stimulation, and increasing stimulates specific aim, reduces the possibility that irrelevant nervous tissue is upset.Stimulate the degree of depth to determine magnetic stimulator can keep the distance of certain stimulus intensity.Have only the high degree of depth that stimulates just might realize effective stimulus to dark cranial nerve tissue.Right existing figure-eight coil (butterfly coil) degree of focus is not enough, causes field stimulation big, the problem that specific aim is not strong, and the probability that irrelevant nervous tissue is upset is big.
[summary of the invention]
The object of the present invention is to provide a kind of two 8 font transcranial magnetic stimulation coils, promoted the effect of transcranial magnetic stimulation, to solve the insufficient problem of traditional figure-eight coil degree of focus with higher degree of focus.
To achieve these goals, the present invention adopts following technical scheme:
A kind of two 8 font transcranial magnetic stimulation coils are connected to form by first figure-eight coil and second figure-eight coil, and the center of first figure-eight coil and second figure-eight coil overlaps on the space; And the circular coil that two radiuses of second figure-eight coil are Ri is positioned at two circular coils that radius is Ro, wherein Ro＞Ri of the first corresponding figure-eight coil.
The present invention further improves and is: Ri:Ro=(0.4 ~ 0.5): 1.
The present invention further improves and is: Ri:Ro=0.5:1.
The present invention further improves and is: the number of turn Ni of second figure-eight coil is (1 ~ 10) with the ratio of the number of turn No of first figure-eight coil: 1.
The present invention further improves and is: first figure-eight coil and second figure-eight coil are positioned at same plane.
Compared with prior art; The present invention has the following advantages: a kind of two 8 font transcranial magnetic stimulation coils of the present invention; Through at two littler circular coils of radius of traditional figure-eight coil set inside, and through arrangement of conductors locus, inner-outer coil radius and the inner-outer coil number of turn to improve the degree of focus that coil stimulates; Field stimulation is concentrated, and with strong points, the probability that irrelevant nervous tissue is upset significantly reduces.
[description of drawings]
The HPR comparison diagram of the figure-eight coil when Fig. 1 is the different stimulated degree of depth and two figure-eight coils (Double-butterfly coil);
Fig. 2 is an according to the invention pair of figure-eight coil structure chart;
Fig. 3 is a kind of through the living circuit diagram of cranium magnetic thorn pulse excitation;
Fig. 4 is the induction field size distribution figure that two 8 word line circles produce on certain depth;
When Fig. 5 is the different stimulated degree of depth, the graph of a relation of coil HPR and inside and outside umber of turn ratio;
Fig. 6 is an outer winding radius when being 3.5cm, the graph of a relation of HPR and Ni/No and Ri/Ro.
[specific embodiment]
Below in conjunction with accompanying drawing the present invention is done and to describe in further detail.
See also shown in Figure 2; A kind of two 8 font transcranial magnetic stimulation coils of the present invention are connected to form by the figure-eight coil of two different winding radiuses, and the figure-eight coil of two different winding radiuses is positioned at same plane; The center of two figure-eight coils overlaps on the space; Flow through same electric current I in two coils, the electric current I direction plays the effect of strengthening the center field intensity in the center in the same way.Two 8 font transcranial magnetic stimulation coils are connected after the pulse power, under the function of current, produce the alternating magnetic field of high degree of focus, can be used to carry out the experiment and the treatment of transcranial magnetic stimulation.The two figure-eight coils of the present invention can use various plain conductor coilings to form, and adopting not, the mode of shield electromagnetic makes coil arrangement become Fig. 2 structure.
The two 8 font transcranial magnetic stimulation coils of the present invention are compared with traditional figure-eight coil, reach the purpose that improves degree of focus through arrangement of conductors locus, inner-outer coil radius and the inner-outer coil number of turn.See also shown in Figure 4ly, be the induction field size distribution that the two 8 word line circles of the present invention produce on certain depth, the induction field that can find out the two 8 word line circles of the present invention distributes similar with 8 word line loop-shaped, but main peak is narrower, helps improving degree of focus.The inside and outside winding radius of two 8 font transcranial magnetic stimulation coils is respectively Ri, Ro; Inside and outside umber of turn is Ni, No, in order to quantize degree of focus, introduces half power value zone (Half Power Region; HPR); Be that electric field magnitude is the area in the zone of forming of having a few at maximum decay-3dB place, HPR is more little, and then degree of focus is good more.The degree of focus of relatively two 8 font transcranial magnetic stimulation coils and figure-eight coil is calculated the HPR value on the different stimulated degree of depth, and wherein, the radius of figure-eight coil is 3.5cm, and the number of turn is 4 circles; Two 8 font transcranial magnetic stimulation coils are selected parameters optimization, i.e. Ro=3.5cm, and Ri=2cm, No=4, Ni=8, the result is as shown in Figure 1; When stimulating the degree of depth from 1cm to 4cm, to change, the HPR of two 8 font transcranial magnetic stimulation coils is little than 8 fonts all the time, explain that the degree of focus of pair 8 font transcranial magnetic stimulation coils is better than the degree of focus of figure-eight coil.
Provide some references at this, for example get Ro=3.5cm, Ri=2.0cm stimulates depth H to get 2.0cm respectively, 3.0cm and 4.0cm, and I=5kA, f=10kHz, Ni/No get 1 to 10.HPR result is as shown in Figure 5, and is visible, stimulates the degree of depth dark more, and HPR is big more, and degree of focus is poor more; When inside and outside umber of turn ratio increased, its HPR reduced, but the speed that reduces increases with the number of turn and slow down, and therefore, in order to improve the degree of focus of two figure-eight coils as far as possible, umber of turn is slightly more than outer umber of turn in should making.If get Ro=3.5cm, H=3.0cm, I=5kA, f=10kHz, Ni/No get 1 to 10, Ri/Ro gets 0.1 to 0.9, and is as shown in Figure 6, for certain Ni/No, when Ri/Ro near 0.5 the time, HPR obtains minima.Ni/No is near 10 o'clock, makes Ri/Ro that HPR obtains optimal value near 0.4, when Ni/No near 1 the time, make Ri/Ro that HPR obtains optimal value near 0.5.In order to reach best degree of focus, Ri/Ro=0.5 is adopted in suggestion.
When being connected to pulse generating circuit, coil to note the length and the method for arranging that go between, simple as far as possible, in order to avoid have influence on the coil effect.Provide a kind of pulse generating circuit at this, as shown in Figure 3, L is two figure-eight coils; C is a charging capacitor, and R is a current-limiting resistance, and D is a commutation diode, and these elements have been formed the rectification charging loop.The control signal of being sent by control circuit triggers the IGCT conducting, makes electric capacity to coil discharge, produces sinusoidal pulse electric current, is used for transcranial magnetic stimulation.
Claims (5)
1. two 8 font transcranial magnetic stimulation coils is characterized in that, connected to form by first figure-eight coil and second figure-eight coil, the center of first figure-eight coil and second figure-eight coil overlaps on the space; And the circular coil that two radiuses of second figure-eight coil are Ri is positioned at two circular coils that radius is Ro, wherein Ro＞Ri of the first corresponding figure-eight coil.
2. two 8 font transcranial magnetic stimulation coils according to claim 1 is characterized in that Ri:Ro=(0.4 ~ 0.5): 1.
3. two 8 font transcranial magnetic stimulation coils according to claim 1 is characterized in that Ri:Ro=0.5:1.
4. two 8 font transcranial magnetic stimulation coils according to claim 1 is characterized in that the number of turn Ni of second figure-eight coil is (1 ~ 10) with the ratio of the number of turn No of first figure-eight coil: 1.
5. two 8 font transcranial magnetic stimulation coils according to claim 1 is characterized in that first figure-eight coil and second figure-eight coil are positioned at same plane.
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| CN201210210607.3A CN102727997B (en) | 2012-06-25 | 2012-06-25 | Two 8-shaped cerebral magnetic stimulation coil |
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| CN201210210607.3A CN102727997B (en) | 2012-06-25 | 2012-06-25 | Two 8-shaped cerebral magnetic stimulation coil |
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| CN102727997B CN102727997B (en) | 2015-08-05 |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105435371A (en) * | 2015-12-17 | 2016-03-30 | 天津大学 | 8-shaped coil transcranial magnetic stimulation system based on magnetic resonant coupling principle |
| CN106075730A (en) * | 2016-06-07 | 2016-11-09 | 成都信息工程大学 | A kind of electromagnetic excitation method realizing time-scale extension with multiple activation source class connection |
| CN107469233A (en) * | 2017-08-30 | 2017-12-15 | 天津大学 | Quatrefoil coil transcranial magnetic stimulation system based on magnetic resonance coupling principle |
| CN109621209A (en) * | 2018-12-29 | 2019-04-16 | 北京神畅科技发展有限公司 | A kind of inside and outside reversal circle cerebral magnetic stimulation coil |
| WO2019164471A1 (en) * | 2018-02-20 | 2019-08-29 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
| US11000693B2 (en) | 2018-02-20 | 2021-05-11 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
| CN113440731A (en) * | 2021-08-11 | 2021-09-28 | 成都理工大学 | Asymmetric special-shaped coil for craniocerebral electromagnetic stimulation and craniocerebral electromagnetic stimulation system |
| CN113679950A (en) * | 2021-08-30 | 2021-11-23 | 华南理工大学 | 8-shaped transcranial magnetic stimulation coil, magnetic stimulation device and magnetic stimulation system |
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| US20050154426A1 (en) * | 2002-05-09 | 2005-07-14 | Boveja Birinder R. | Method and system for providing therapy for neuropsychiatric and neurological disorders utilizing transcranical magnetic stimulation and pulsed electrical vagus nerve(s) stimulation |
| CN101869478A (en) * | 2009-04-24 | 2010-10-27 | 株式会社东芝 | MR imaging apparatus and radio-frequency coil |
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2012
- 2012-06-25 CN CN201210210607.3A patent/CN102727997B/en not_active Expired - Fee Related
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| US20050154426A1 (en) * | 2002-05-09 | 2005-07-14 | Boveja Birinder R. | Method and system for providing therapy for neuropsychiatric and neurological disorders utilizing transcranical magnetic stimulation and pulsed electrical vagus nerve(s) stimulation |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105435371A (en) * | 2015-12-17 | 2016-03-30 | 天津大学 | 8-shaped coil transcranial magnetic stimulation system based on magnetic resonant coupling principle |
| CN106075730A (en) * | 2016-06-07 | 2016-11-09 | 成都信息工程大学 | A kind of electromagnetic excitation method realizing time-scale extension with multiple activation source class connection |
| CN106075730B (en) * | 2016-06-07 | 2018-06-12 | 成都信息工程大学 | It is a kind of to join the electromagnetic excitation method for realizing time-scale extension with multiple activation source level |
| CN107469233A (en) * | 2017-08-30 | 2017-12-15 | 天津大学 | Quatrefoil coil transcranial magnetic stimulation system based on magnetic resonance coupling principle |
| WO2019164471A1 (en) * | 2018-02-20 | 2019-08-29 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
| US11000693B2 (en) | 2018-02-20 | 2021-05-11 | Neuronetics, Inc. | Magnetic stimulation coils and ferromagnetic components for treatment and diagnostic procedures |
| CN109621209A (en) * | 2018-12-29 | 2019-04-16 | 北京神畅科技发展有限公司 | A kind of inside and outside reversal circle cerebral magnetic stimulation coil |
| CN113440731A (en) * | 2021-08-11 | 2021-09-28 | 成都理工大学 | Asymmetric special-shaped coil for craniocerebral electromagnetic stimulation and craniocerebral electromagnetic stimulation system |
| CN113679950A (en) * | 2021-08-30 | 2021-11-23 | 华南理工大学 | 8-shaped transcranial magnetic stimulation coil, magnetic stimulation device and magnetic stimulation system |
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| CN102727997B (en) | 2015-08-05 |
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Granted publication date: 20150805 Termination date: 20180625 |