CN111388868A

CN111388868A - Ox horn-like transcranial magnetic stimulation coil for increasing magnetic field depth

Info

Publication number: CN111388868A
Application number: CN202010334023.1A
Authority: CN
Inventors: 杨绍杰
Original assignee: Individual
Current assignee: Individual
Priority date: 2020-04-24
Filing date: 2020-04-24
Publication date: 2020-07-10

Abstract

The invention discloses a ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth, which comprises a coil, wherein the coil is in an arc horn shape formed by winding a conducting wire in an encircling manner, the coil continuously forms an arc, openings at two ends of the coil are opposite, the coil is integrally encircled to form an ox horn-shaped structure, the distance between the central points of the cross sections at the two ends of the coil is 5-20cm, the inner diameters of the two ends of the coil are all 1-25cm, and the vertical axial included angle of the cross sections at the two ends of the coil is 0-180 degrees.

Description

Ox horn-like transcranial magnetic stimulation coil for increasing magnetic field depth

Technical Field

The invention belongs to the field of transcranial magnetic stimulation treatment equipment, and particularly relates to a ox horn-shaped transcranial magnetic stimulation coil for increasing the depth of a magnetic field.

Background

Transcranial Magnetic Stimulation (TMS) is created by Barker in 1985, based on the principle of electromagnetic induction and electromagnetic conversion, a magnetic field generated by transient current of a stimulation coil penetrates skull to generate induced current to stimulate neurons to trigger a series of physiological and biochemical reactions, and as a non-invasive stimulation technology, TMS acts on human brain to cause the change of nerve activity, and can detect the change of motion evoked potential, brain electrical activity, brain blood flow, metabolism and brain function state. The microscopic effects include changes in cell membrane potential, action potential, neurotransmitters, receptors, synapses, and neuroplasticity;

the magnetic stimulation coil is a load of a pulse current generating circuit and is made of conductors with smaller resistivity, and when the shapes of the coils are different, the distribution of the generated induced electric fields is also different, so that the stimulation intensity, the stimulation depth, the focusing power, the stimulation angle and the like are directly influenced. The design of the coil is critical in TMS studies. In order to accurately and effectively stimulate a target, high requirements are provided for the strength, the stimulation depth, the focusing power and the stimulation direction of an electromagnetic field generated by a coil, the stimulation range can be narrowed by high focusing degree, the stimulation pertinence is enhanced, and the sufficient stimulation depth can ensure that a magnetic stimulation instrument still has certain stimulation strength on tissues below the surface of a human body, so that intracranial nerve tissues can be effectively stimulated, and the existing research comprises a circular coil, an 8-shaped coil, a four-leaf coil, a slinky coil, an H coil and the like; (the research on transcranial magnetic stimulation technology of Lijiang Tao et al advances [ J ] high voltage technology 2016Vol.42(4): 1168-.

Among them, the circular coil appears earliest, has a simple structure, is easy to manufacture and convenient to use, but has a large stimulation range and a poor focusing degree. Experimental data show that as the size of the coil increases, the stimulation depth of the coil increases, but the focality of the magnetic field decreases; the peak value of the induced electric field of the 8-shaped coil is distributed at the junction of the 2 coils, and the focusing degree of the 8-shaped coil is improved to a certain extent compared with that of a circular coil; the focus of the quadralobe coil is greatly improved in the circular connection direction of the 8-shaped coil, but is deteriorated in the vertical direction; the slinky coil is provided with 1 or more coils on a plane vertical to the 8-shaped coil on the basis of the 8-shaped coil, the electric field in the center of the coil can be enhanced, the strength of a negative secondary peak is weakened, and the effect is better when the number of the increased coils is larger; the H-coil is designed by y.roth et al, which is a coil with a plurality of long wires arranged on the surface of the head, the wires presenting a radial distribution, which, although less focused, stimulates the target to deeper layers.

The field intensity of the traditional stimulation coil is rapidly attenuated along with the increase of the depth of a stimulation part, so that transcranial magnetic stimulation is only limited to the cerebral cortex; when deep brain tissues such as medial frontal lobe, inferior cingulum or spinal cone are stimulated, a specially designed deep stimulating coil is needed, 2 double-cone coils (double-cone coils) with the diameter of 110mm and formed by 100 degrees can stimulate deep brain cortex governing pelvic floor muscles and lower limb muscles; the Hesed coil family lead is bent at a right angle in a three-dimensional space, so that magnetic field vectors are superposed at a stimulation part, and deep brain tissues can be effectively stimulated; (Huangbei, Wuhuizhun, Qianzhen Beeffrageen, Wangjun, Zhao Zhenzhen diagnostic transcranial magnetic stimulation research progress Chin J Contemp neuron Neurosurg, April 2017, Vol.17, No. 4300-.

Transcranial magnetic stimulation treatment has the characteristics of non-invasion, no damage, slight side effect and wide clinical indications, so that more and more attention is paid, but at present, transcranial magnetic stimulation has various forms, such as a single coil, an 8-shaped coil, an S L INKY coil, an angled 8-shaped coil and an H-shaped coil, but most of the stimulation depth is insufficient, the positioning direction is unsatisfactory, and the treatment effect is influenced.

Therefore, the design of the coil is the key in the research of transcranial magnetic stimulation treatment, but most of the existing coils for transcranial magnetic stimulation treatment cannot constrain and self-guide the magnetic force lines, and cannot achieve the effects of high concentration of magnetic stimulation, improvement of the depth of magnetic stimulation and improvement of the utilization rate of a magnetic field, and cannot achieve the effect of improving the biological effect.

The invention content is as follows:

the present invention aims to solve the above problems by providing a ox horn-like transcranial magnetic stimulation coil with increased magnetic field depth, which solves the problems mentioned in the background art.

In order to solve the above problems, the present invention provides a technical solution:

the ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth comprises a coil, wherein the coil is in an arc horn shape surrounded by conducting wires, the coil continuously forms an arc shape, and openings at two ends of the coil are opposite.

Preferably, the coil is integrally surrounded to form a horn-shaped structure.

Preferably, the distance between the center points of the cross sections of the two ends of the coil is 5-20 cm.

Preferably, the inner diameter of each of the two ports of the coil is between 1 and 25 cm.

Preferably, the vertical axial included angle of the cross section of the two ends of the coil is 0-180 degrees.

Preferably, the magnetic field intensity distribution around the coil has a uniform peak-like shape.

Preferably, the magnetic lines of force at the two ends of the coil are distributed in a mutually attracting and overlapping form.

Preferably, the coil may be surrounded by a single or multiple layers of wire.

The invention has the beneficial effects that: the invention can restrain and self-guide the magnetic force lines by arranging the ox horn-shaped coil, and can achieve the effects of highly concentrating the magnetic stimulation, improving the depth of the magnetic stimulation and improving the utilization rate of a magnetic field and the biological effect compared with the existing coil for transcranial magnetic stimulation.

Description of the drawings:

for ease of illustration, the invention is described in detail by the following detailed description and the accompanying drawings.

FIG. 1 is a schematic structural view of the present invention;

FIG. 2 is a schematic diagram of the present invention;

FIG. 3 is a schematic view of the axial included angle of the coil ports of the present invention;

FIG. 4 is a schematic diagram of the magnetic field strength between two ports of the coil of the present invention;

FIG. 5 is a schematic illustration of the magnetic field strength distribution of the present invention;

fig. 6 is a schematic diagram of the distribution of magnetic lines at both ends of the coil of the present invention.

In the figure: 1. and a coil.

The specific implementation mode is as follows:

as shown in fig. 1 to 6, the following technical solutions are adopted in the present embodiment:

example (b):

a ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth comprises a coil 1, wherein the coil 1 is in an arc horn shape formed by winding a conducting wire in a surrounding mode, the coil 1 continuously forms an arc shape, and openings at two ends of the coil 1 are opposite.

The coil 1 is integrally surrounded to form a horn-shaped structure, so that the diameters of the two ports of the coil 1 are different, and the diameters of the two ports of the coil 1 are not limited to be different in size and can be manufactured to be the same in size.

Wherein, the distance between the central points of the cross sections at the two ends of the coil 1 is 5-20cm, which is convenient for optimizing the whole structure.

The inner diameters of two ports of the coil 1 are all between 1 cm and 25cm, so that the magnetic lines of force can be restrained and guided better.

The vertical axial included angle of the cross sections at the two ends of the coil 1 is 0-180 degrees, so that the included angle between the two ports of the coil 1 is better limited.

Wherein, the magnetic field intensity distribution around the coil 1 is in a uniform mountain peak shape, and the magnetic field intensity distribution around the coil 1 is uniform.

The magnetic lines of force at the two ends of the coil 1 are distributed in a mutually attracting and overlapping form, so that the magnetic stimulation is highly concentrated, and the transcranial magnetic stimulation treatment effect is improved better.

The coil 1 can be formed by winding a single-layer or multi-layer wire, so that the coil 1 can be manufactured better.

The using state of the invention is as follows: the coil 1 can be single-layer or multilayer, can be densely wound or alternately wound, can use magnetic conduction material to increase magnetic field intensity in the inside of coil 1 simultaneously, also can not use, and the perpendicular axial contained angle of the both ends cross-section of coil 1 keeps between 0-180 simultaneously all can, and the cross-section of coil 1 can be various shapes in addition, for example: in addition, as shown in figure 4, ANSYS magnetic field simulation software is used for simulating and calculating the magnetic field intensity distribution characteristics of the obtained coil (the inner diameter of a large-caliber end of the coil is 15cm, the inner diameter of a small-caliber end of the coil is 2cm, the thickness of the coil is 2cm, and a stable magnetic field with the current of 1000A), under the specific state, the magnetic field intensity of the large-caliber end of the coil 1 is maintained at a position of 4cm above 0.5 tesla, the maximum magnetic field intensity of the small-caliber end of the coil 1 reaches 1.2 tesla, and the magnetic field intensity of the coil 1 is maintained at a position of 2.2cm at 0.5 tesla, meanwhile, under the stable magnetic fields of different currents, the distribution curves of the magnetic field strengths of the coils 1 with different sizes are kept approximately the same as those shown in FIG. 4; as shown in fig. 5, the distribution of the magnetic field strength is in a uniform peak-like shape, which is significantly different from the magnetic field distribution shape of the circular coil in the aforementioned coil main type, and as shown in fig. 6, the magnetic line distribution of the coil shows that both ends attract and overlap each other, thereby effectively utilizing the magnetic field.

While there have been shown and described what are at present considered to be the fundamental principles of the invention and its essential features and advantages, it will be understood by those skilled in the art that the invention is not limited by the embodiments described above, which are merely illustrative of the principles of the invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the invention as defined by the appended claims and their equivalents.

Claims

1. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth comprises a coil (1) and is characterized in that the coil (1) is in an arc horn shape formed by winding a lead in a surrounding mode, the coil (1) continuously forms an arc shape, and openings at two ends of the coil (1) are opposite.

2. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the coil (1) is integrally surrounded to form an ox horn-shaped structure.

3. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the distance between the cross-sectional center points of the two ends of the coil (1) is 5-20 cm.

4. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the inner diameter of each of two ports of the coil (1) is between 1 cm and 25 cm.

5. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the perpendicular axial included angle of the cross section of the two ends of the coil (1) is 0-180 degrees.

6. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the magnetic field intensity distribution around the coil (1) is in a uniform mountain-peak-like shape.

7. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the magnetic force lines at the two ends of the coil (1) are distributed in a mutually attractive and superposed form.

8. The ox horn-like transcranial magnetic stimulation coil for increasing the magnetic field depth according to claim 1, wherein the coil (1) can be surrounded by single-layer or multi-layer wires.