CN102727854B - Traditional Chinese medicine for treatment of gastric cancer - Google Patents
Traditional Chinese medicine for treatment of gastric cancer Download PDFInfo
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- CN102727854B CN102727854B CN 201210230057 CN201210230057A CN102727854B CN 102727854 B CN102727854 B CN 102727854B CN 201210230057 CN201210230057 CN 201210230057 CN 201210230057 A CN201210230057 A CN 201210230057A CN 102727854 B CN102727854 B CN 102727854B
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- 239000003814 drug Substances 0.000 title claims abstract description 28
- 208000005718 Stomach Neoplasms Diseases 0.000 title claims abstract description 26
- 206010017758 gastric cancer Diseases 0.000 title claims abstract description 26
- 201000011549 stomach cancer Diseases 0.000 title claims abstract description 26
- 238000011282 treatment Methods 0.000 title claims abstract description 22
- 241000195474 Sargassum Species 0.000 claims abstract description 11
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940079593 drug Drugs 0.000 claims description 10
- 210000002784 stomach Anatomy 0.000 abstract description 6
- 208000005392 Spasm Diseases 0.000 abstract description 5
- 230000007812 deficiency Effects 0.000 abstract description 5
- 238000010792 warming Methods 0.000 abstract description 5
- 210000000952 spleen Anatomy 0.000 abstract description 4
- 240000001659 Oldenlandia diffusa Species 0.000 abstract 1
- 244000179560 Prunella vulgaris Species 0.000 abstract 1
- 235000010674 Prunella vulgaris Nutrition 0.000 abstract 1
- 244000273928 Zingiber officinale Species 0.000 abstract 1
- 235000006886 Zingiber officinale Nutrition 0.000 abstract 1
- 235000008397 ginger Nutrition 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000002040 relaxant effect Effects 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 18
- 238000002651 drug therapy Methods 0.000 description 6
- 238000011084 recovery Methods 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 5
- 241001529739 Prunella <angiosperm> Species 0.000 description 4
- 231100000614 poison Toxicity 0.000 description 4
- 239000003440 toxic substance Substances 0.000 description 4
- 201000011510 cancer Diseases 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 208000034507 Haematemesis Diseases 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 230000004596 appetite loss Effects 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 208000019017 loss of appetite Diseases 0.000 description 2
- 235000021266 loss of appetite Nutrition 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 230000004083 survival effect Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000283690 Bos taurus Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010024642 Listless Diseases 0.000 description 1
- 206010027336 Menstruation delayed Diseases 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- 210000002318 cardia Anatomy 0.000 description 1
- 230000000973 chemotherapeutic effect Effects 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 210000002249 digestive system Anatomy 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000009854 hydrometallurgy Methods 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 208000017971 listlessness Diseases 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 201000011591 microinvasive gastric cancer Diseases 0.000 description 1
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- 231100000957 no side effect Toxicity 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 210000004203 pyloric antrum Anatomy 0.000 description 1
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Abstract
The invention belongs to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine for treatment of gastric cancer. The traditional Chinese medicine is prepared from the following pharmaceutical ingredients by weight: 15 to 25 parts of ginger, 5 to 15 parts by Fructus Ziziphi Jujubae, 15 to 25 parts of Prunella vulgaris, 15 to 25 parts of Sargassum, 20 to 30 parts of radix glycyrrhizae preparata, 20 to 30 parts of radix paeoniae alba and 10 to 15 parts of oldenlandia diffusa. The traditional Chinese medicine in the invention has the efficacies of warming spleen and stomach, tonifying deficiency syndrome, softening hardness and dispelling stagnation, clearing heat and removing toxicity as well as relaxing spasm and relieving pain.
Description
Technical field:
The invention belongs to the field of Chinese medicines, particularly a kind of Chinese medicine for the treatment of gastric cancer.
Background technology:
Gastric cancer originates from the mucomembranous epithelial cell on the top layer of coat of the stomach, can betide each position (the gastric antrum pylorus district at most, take second place in the cardia district at the bottom of the stomach, body of stomach is less slightly) of stomach, can invade different depth and the range of coat of the stomach.
Surplus the annual New Development gastric cancer 100 in the whole world ten thousand, China accounts for 42%, and dead about 800,000, China accounts for 35%, is one of the highest country of incidence gastric cancer rate and mortality rate, and M ﹠ M all is that the world average level twice is many.Compatriots' cause of the death 1/4 is cancer at present, and 1/4 of the cancer cause of the death is gastric cancer, and in the alimentary system malignant tumour death, about half is died from gastric cancer.Gastric cancer curative effect and stadium sooner or later and diagnoses and treatment and means closely related, early gastric cancer can be survived more than 5 years or healing through 90% above patient after enough treatments, and phase patients with gastric cancer is very late treated back 5 years survival rate less thaies 5%.Therefore, early find it is the key of improving curative effect, improving survival rate.Present Therapeutic Method gastric cancer is based on operation, but operative treatment and be not suitable for the treatment of gastric cancer, Drug therapy then only limits to not have the duodenal ulcer of complication.
Summary of the invention:
Comprehensively above-mentioned, in order to overcome the deficiency of prior art problem, it is simple that the present invention has developed a kind of configuration, the Chinese medicine for the treatment of gastric cancer evident in efficacy.
The object of the present invention is achieved like this: a kind of Chinese medicine that is used for the treatment of gastric cancer is prepared from by following parts of medicines by weight: the Sargassum of the Fructus Jujubae of the Rhizoma Zingiberis Recens of 15～25 parts by weight, 5～15 parts by weight, the Spica Prunellae of 15～25 parts by weight, 15～25 parts by weight, the Radix Glycyrrhizae Preparata of 20～30 parts by weight, the Radix Paeoniae Alba of 20～30 parts by weight, the Herba Hedyotidis Diffusae of 10～15 parts by weight.
Technical scheme of the present invention can be achieved in that
A kind of Chinese medicine that is used for the treatment of gastric cancer is prepared from by following parts of medicines by weight: the Sargassum of the Fructus Jujubae of the Rhizoma Zingiberis Recens of 20 parts by weight, 10 parts by weight, the Spica Prunellae of 20 parts by weight, 20 parts by weight, the Radix Glycyrrhizae Preparata of 25 parts by weight, the Radix Paeoniae Alba of 25 parts by weight, the Herba Hedyotidis Diffusae of 12 parts by weight.
The present invention mixes each raw material, is ground into fine powder, directly take, and every day three times, each 1-2 gram, warm water takes.
The course for the treatment of: 30 days is a course for the treatment of, need take the 3-8 course for the treatment of.
Pharmacology of the present invention and document are according to being:
Rhizoma Zingiberis Recens: suffering, tepor; Effect: the cold expelling that induces sweat, warming middle-JIAO to arrest vomiting, preventing phlegm from forming and stopping coughing.
Fructus Jujubae: sweet, temperature; Effect: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind.
Spica Prunellae: hot, bitter, cold; Effect: relieve inflammation or internal heat, make eye bright, eliminating stagnation, detumescence.
Sargassum: salty, cold; Effect: hard masses softening and resolving, expectorant, diuretic.
Radix Glycyrrhizae Preparata: sweet, flat; Effect: spleen reinforcing stomach function regulating, Yiqi and vein recovery.
The Radix Paeoniae Alba: bitter, sour, be slightly cold; Effect: nourish blood and seek; Relieving spasm to stop pain; The yin fluid astringing suppressing the hyperactive liver.
Herba Hedyotidis Diffusae: bitter, sour, be slightly cold; Effect: heat-clearing and toxic substances removing, dampness removing.
Rhizoma Zingiberis Recens among the present invention, Fructus Jujubae is warming middle-Jiao and tonifying deficiency, Spica Prunellae, Sargassum hard masses softening and resolving, Radix Glycyrrhizae Preparata spleen reinforcing stomach function regulating, Yiqi and vein recovery, Radix Paeoniae Alba yin fluid astringing and battalion, relieving spasm to stop pain, Herba Hedyotidis Diffusae heat-clearing and toxic substances removing, all medicines share the merit of playing warming middle-Jiao and tonifying deficiency, hard masses softening and resolving, heat-clearing and toxic substances removing, relieving spasm to stop pain altogether.
Beneficial effect of the present invention:
The present invention is formulated with pure Chinese medicine, and scientific formulation is reasonable, and configuration is simple, has no side effect, and curative effect is short, and instant effect has the effect of warming middle-Jiao and tonifying deficiency, hard masses softening and resolving, heat-clearing and toxic substances removing, relieving spasm to stop pain.
The specific embodiment:
Be described in further details below in conjunction with the present invention of embodiment:
Embodiment 1: a kind of Chinese medicine that is used for the treatment of gastric cancer is formed by the medication preparation of following weight grams: the Sargassums of the Fructus Jujubaes of the Rhizoma Zingiberis Recenss of 20 grams, 10 grams, the Spica Prunellaes of 20 grams, 20 grams, the Radix Glycyrrhizae Preparata of 25 grams, the Radix Paeoniae Albas of 25 grams, the Herba Hedyotidis Diffusaes of 12 grams.
Embodiment 2: a kind of Chinese medicine that is used for the treatment of gastric cancer is formed by the medication preparation of following weight grams: the Sargassums of the Fructus Jujubaes of the Rhizoma Zingiberis Recenss of 25 grams, 15 grams, the Spica Prunellaes of 25 grams, 25 grams, the Radix Glycyrrhizae Preparata of 30 grams, the Radix Paeoniae Albas of 30 grams, the Herba Hedyotidis Diffusaes of 15 grams.
Embodiment 3: a kind of Chinese medicine that is used for the treatment of gastric cancer is formed by the medication preparation of following weight grams: the Sargassums of the Fructus Jujubaes of the Rhizoma Zingiberis Recenss of 15 grams, 5 grams, the Spica Prunellaes of 15 grams, 15 grams, the Radix Glycyrrhizae Preparata of 20 grams, the Radix Paeoniae Albas of 20 grams, the Herba Hedyotidis Diffusaes of 10 grams.
Embodiment 4: a kind of Chinese medicine that is used for the treatment of gastric cancer is formed by the medication preparation of following weight grams: the Sargassums of the Fructus Jujubaes of the Rhizoma Zingiberis Recenss of 18 grams, 9 grams, the Spica Prunellaes of 22 grams, 21 grams, the Radix Glycyrrhizae Preparata of 19 grams, the Radix Paeoniae Albas of 23 grams, the Herba Hedyotidis Diffusaes of 13 grams.
Chinese medicine among the embodiment 1-4 mixes each raw material in the preparation, is ground into fine powder, directly takes, and every day three times, each 1-2 gram takes with warm water.
The present invention is not limited to above-mentioned preferred forms, and other any identical with the present invention or akin products that anyone draws under enlightenment of the present invention all drop within protection scope of the present invention.
The result of clinical observation of the present invention is as follows:
Criterion of therapeutical effect:
Cure: cancerous cell is all eliminated in the patient's transference cure, body.
Effectively: patient's symptom makes moderate progress, the complete effectively control of cancerous cell in the body, but can not all eliminate.
Invalid: through a period of time treatment, the patient does not have any improvement.
Curative effect of medication is observed situation:
Drug therapy 94 people of the present invention, healing person 64 people, responder 18 people, nonresponder 12 people, effective percentage 87%.
Model case:
Cao: the man, 37 years old, Yuzhou of Henan people, gastric cancer is early stage, finds that by the here Drug therapy one month takes effect, recovery from illness in four months.
Zhao: the woman, 54 years old, Henan hydrometallurgy people, gastric cancer mid-term, epigastrium often has feeling of repletion, loss of appetite, malaise, once by chemotherapeutic treatment, but side effect is big, and normal cell also is killed, and by the here Drug therapy, two months take effect, recovery from illness in six months.
Cattle: the man, 49 years old, table mountain Jiao Dian people loss of appetite, became thin day by day in gastric cancer mid-term, and a small amount of hematemesis is arranged, and by the here Drug therapy, two months take effect, recovery from illness in six months.
Zhang: the woman, 42 years old, table mountain Xinhua District people became thin, anemia, inappetence, listlessness in gastric cancer late period, a large amount of hematemesis, by the here Drug therapy, three months take effect, recovery from illness in eight months.
Claims (2)
1. a Chinese medicine that is used for the treatment of gastric cancer is characterized in that: be prepared from by following parts of medicines by weight: the Sargassum of the Fructus Jujubae of the Rhizoma Zingiberis Recens of 15～25 parts by weight, 5～15 parts by weight, the Spica Prunellae of 15～25 parts by weight, 15～25 parts by weight, the Radix Glycyrrhizae Preparata of 20～30 parts by weight, the Radix Paeoniae Alba of 20～30 parts by weight, the Herba Hedyotidis Diffusae of 10～15 parts by weight.
2. the Chinese medicine that is used for the treatment of gastric cancer according to claim 1 is characterized in that: be prepared from by following parts of medicines by weight: the Sargassum of the Fructus Jujubae of the Rhizoma Zingiberis Recens of 20 parts by weight, 10 parts by weight, the Spica Prunellae of 20 parts by weight, 20 parts by weight, the Radix Glycyrrhizae Preparata of 25 parts by weight, the Radix Paeoniae Alba of 25 parts by weight, the Herba Hedyotidis Diffusae of 12 parts by weight.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210230057 CN102727854B (en) | 2012-07-05 | 2012-07-05 | Traditional Chinese medicine for treatment of gastric cancer |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210230057 CN102727854B (en) | 2012-07-05 | 2012-07-05 | Traditional Chinese medicine for treatment of gastric cancer |
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| Publication Number | Publication Date |
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| CN102727854A CN102727854A (en) | 2012-10-17 |
| CN102727854B true CN102727854B (en) | 2013-08-28 |
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| CN 201210230057 Active CN102727854B (en) | 2012-07-05 | 2012-07-05 | Traditional Chinese medicine for treatment of gastric cancer |
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| CN108404100A (en) * | 2018-05-30 | 2018-08-17 | 衢州职业技术学院 | Add application of the taste Huangqi Jianzhong Tang in inhibiting tumor-associated macrophage in miR-574-5p expression |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204522A (en) * | 1997-07-08 | 1999-01-13 | 孙贤华 | Chinese prescription medicine for treatment of digestive tract tumour and preparation method thereof |
| CN1214919A (en) * | 1997-10-20 | 1999-04-28 | 吴戈 | Oral liquid for anti-cancer |
| CN1546158A (en) * | 2003-12-16 | 2004-11-17 | 夏庆君 | Specific medicine for treating cancer and preparing process |
| CN1864730A (en) * | 2005-05-20 | 2006-11-22 | 米兴华 | A cancer-treating medicine |
| CN1903346A (en) * | 2006-08-01 | 2007-01-31 | 于世琴 | Traditional Chinese medicine for treating gastric carcinoma |
| CN102441135A (en) * | 2010-10-09 | 2012-05-09 | 安徽科创中药天然药物研究所有限责任公司 | Traditional Chinese medicine for treating lung cancer and stomach cancer, its preparation method and quality control technology |
-
2012
- 2012-07-05 CN CN 201210230057 patent/CN102727854B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1204522A (en) * | 1997-07-08 | 1999-01-13 | 孙贤华 | Chinese prescription medicine for treatment of digestive tract tumour and preparation method thereof |
| CN1214919A (en) * | 1997-10-20 | 1999-04-28 | 吴戈 | Oral liquid for anti-cancer |
| CN1546158A (en) * | 2003-12-16 | 2004-11-17 | 夏庆君 | Specific medicine for treating cancer and preparing process |
| CN1864730A (en) * | 2005-05-20 | 2006-11-22 | 米兴华 | A cancer-treating medicine |
| CN1903346A (en) * | 2006-08-01 | 2007-01-31 | 于世琴 | Traditional Chinese medicine for treating gastric carcinoma |
| CN102441135A (en) * | 2010-10-09 | 2012-05-09 | 安徽科创中药天然药物研究所有限责任公司 | Traditional Chinese medicine for treating lung cancer and stomach cancer, its preparation method and quality control technology |
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| CN102727854A (en) | 2012-10-17 |
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