CN104524207A - Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles - Google Patents
Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles Download PDFInfo
- Publication number
- CN104524207A CN104524207A CN201410796927.0A CN201410796927A CN104524207A CN 104524207 A CN104524207 A CN 104524207A CN 201410796927 A CN201410796927 A CN 201410796927A CN 104524207 A CN104524207 A CN 104524207A
- Authority
- CN
- China
- Prior art keywords
- parts
- herba
- portions
- chinese medicinal
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/02—Algae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/486—Millettia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses traditional Chinese medicine particles for treating erythema nodosum and a preparation method of the traditional Chinese medicine particles and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine particles disclosed by the invention are prepared from the following raw materials: fraxinus malacophylla, latticed enteromorpha dried frond, gynura bicolor, ginkgos, perfoliote knotweed herb, alocasia, rigidleaf cymbidium stems and leaves, herb of glabrous sarcandra, rattans, field horsetails, cantonese ampelopsis, lemons, effuse baliospermum roots and leaves, burmann cinnamon barks, rosa multiflora thunb and evening primrose. The medicinal materials selected by the traditional Chinese medicine particles are appropriate in compatibility, so that the traditional Chinese medicine particles meet theories of traditional Chinese medicine and modern medicine, have the functions of resolving hard lumps, detoxifying and eliminating swelling, promoting blood circulation to remove blood stasis and expelling wind and removing cold, have a remarkable curative effect for treating erythema nodosum, are short in treatment course, safe, reliable, free of any toxic or side effects and miraculous in effect and practical and are worth widely popularizing and applying clinically, and quickly takes effect.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicinal granule and preparation method for the treatment of erythema nodosum.
Background technology
Erythema nodosum is a kind of acute inflammatory disease mainly involving subcutaneus adipose tissue, is more common in young and middle-aged women.It is generally acknowledged that this disease is relevant with many factors.Erythema nodosum is common in shank and stretches side, and clinical manifestation is red or aubergine painful inflammatory tubercle, and young women is common, and the course of disease has limitation, is easy to recurrence.
Erythema nodosum is common in shank and stretches side, and clinical manifestation is red or aubergine painful inflammatory tubercle, and young women is common, and the course of disease has limitation, is easy to recurrence.Premorbid has and infects history or history of taking medicine, and skin lesion occurs suddenly, is bilaterally symmetric subcutaneous nodule, from Semen Viciae fabae to Semen Juglandis very much not etc., number reaches 10 or more, conscious pain or tenderness, medium hardness.Early stage color of the leather is light red, and smooth surface is slightly swelled, and after several days, color of the leather turns dark red or blue or green red, and surface flattens.Before skin lesion is apt to occur in shin, also show in thigh, extension of upper limb side and cervical region, rare in face.
Chronic nodular erythema is different from the feature of acute erythema nodosum, and it often occurs in elderly woman, and skin lesion is one-sided, if bilateral, then asymmetric, except arthralgia, without other General Symptomies; Acute inflammatory nodositas dermatosis, clinical status mainly contains two legs red erythema, tuberosity, heating, joint aches, lassitude.
Chinese medicine is as China's traditional medicine, and have a long history in treatment erythema nodosum, treatment by Chinese herbs can reach to take stopgap measures and effect a permanent cure, successful, cure rate is high, and toxic and side effects is little, not easily recur, therefore select a kind of Chinese medicinal granule to treat the misery that erythema nodosum thoroughly can solve patient.
Summary of the invention
The invention provides a kind of Chinese medicinal granule and preparation method for the treatment of erythema nodosum; Selected by Chinese medicinal granule of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of hard masses softening and resolving, removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling, expelling wind and cold, there is significant curative effect, short treating period, instant effect to treatment erythema nodosum, safe and reliable, without any side effects, special effect is practical, wide popularization and application on clinic.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicinal granule for erythema nodosum, raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Treat a preparation method for the Chinese medicinal granule of erythema nodosum, comprise following processing step:
(1) Cortex Fraxini Malacophyllae Radicis, Enteromorpha clathrata (Roth) Grev. Emend bliding, Herba Gynurae bicoloris, Herba Polygoni cymosi, Rhizoma alcasiae odorae, Herba Cymbidii Penduli, Herba Equiseti Arvinsis, Radix Ampelopsis Cantoniensis, Radix Merremiae hungaiensis, Fructus rosae multiflorae and Radix Oenotherae erythrosepalae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Semen Ginkgo and Fructus Citri Limoniae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Herba Sarcandrae and Cortex Cinnamomi Burmannii are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Calami tetradactyli is cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4), juice, fine powder and filtrate mixing, make granule, obtain the Chinese medicinal granule for the treatment of erythema nodosum of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Cortex Fraxini Malacophyllae Radicis: bitter in the mouth, puckery, cold in nature.Heat clearing away, diuresis, relieving constipation.For cystitis, vesical calculus, dysuria, constipation, malaria." mountain of papers Chinese herbal medicine " carries: " heat clearing away, diuresis, relieving constipation.Control cystitis, vesical calculus, dysuria, constipation, malaria, hyperpyrexia epistaxis.”
Enteromorpha clathrata (Roth) Grev. Emend bliding: salty in the mouth, cold in nature; Return lung, spleen, kidney channel.Hard masses softening and resolving, transforming phlegm and dispersing accumulations, removing toxic substances and promoting subsidence of swelling.Main goiter, scrofula, carbuncle, furuncle, food stagnation, malnutrition due to parasitic infestation, gastral cavity abdominal distention is vexed, epistaxis.
Herba Gynurae bicoloris: acrid in the mouth, sweet, cool in nature.Clearing away heat and cooling blood, removing toxic substances disappears.Main hemoptysis, metrorrhagia, traumatic hemorrhage, dysmenorrhea, dysentery, sore swollen toxin, traumatic injury, ulcer does not restrain for a long time." Fujian Chinese herbal medicine " carries: " hemopoietic stops blooding, clearing heat for detumescence.”
Semen Ginkgo: sweet in the mouth, hardship, puckery, property is put down; Return lung meridian.Astringing lung QI for relieving asthma, leukorrhagia stopping is turbid, urine reducing.Breath with cough for abundant expectoration, leukorrhagia nebulousurine, enuresis frequent micturition." book on Chinese herbal medicine is new again " carries: " QI invigorating nourishes heart, kidney tonifying YIN nourishing, cough-relieving relieving restlessness, and granulation promoting is put on flesh, and evacuation of pus is drawn out pus by applying a plaster to the affected part, the skin ulcer that disappears scabies cellulitis tumor.”
Herba Polygoni cymosi: sour in the mouth, cold nature.Heat-clearing and toxic substances removing, inducing diuresis to remove edema.For upper respiratory tract infection, tracheitis, pertussis, acute tonsillitis, enteritis, dysentery, oedema due to nephritis; Herpes zoster is controlled in external, eczema, carbuncle furuncle and phyma poison, venom.
Rhizoma alcasiae odorae: taste is micro-pungent, puckery, cold in nature; GUIXIN, liver, gallbladder, large intestine channel.Heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, mass dissipating and swelling eliminating.Cure mainly influenza, flu, stomachache, pulmonary tuberculosis, rheumatic ostalgia, furuncle, swollen ulcer drug, scrofula, attached bone carbuncle, class is bald, scabies, worm venom.
Herba Cymbidii Penduli: sweet in the mouth, pungent, property is put down.Nourishing the lung to arrest cough, dissipating blood stasis regulating menstruation.For hemoptysis of pulmonary tuberculosis, bronchitis, pneumonia, breathes with cough, pharyngolaryngitis, menoxenia, leucorrhea." choosing of Simao, Yunnan Chinese herbal medicine " carries: " relieving cough and resolving phlegm, dissipating blood stasis for subsidence of swelling, hemostasis and anti-inflammation.Control pulmonary tuberculosis, pneumonia, tracheobronchitis, breath with cough, the fracture injury of tendon and muscle.”
Herba Sarcandrae: bitter in the mouth, pungent, property is put down; GUIXIN, Liver Channel.Anti-inflammation, clearing away heat and cooling blood, speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.For heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury.Modern medicine study confirms, can strengthen immunologic function, and have regulating action to immunologic function, and have certain bacteriostasis.
Herba Calami tetradactyli: bitter in the mouth, micro-salty, hot in nature; Return liver, lung meridian.Diaphoresis is dispeled the wind, promoting blood circulation and hemostasis.Cure mainly anemofrigid cold, rheumatoid arthritis, traumatic injury, amenorrhea, traumatic hemorrhage." Yunnan Chinese herbal medicine " carries: " hemostasis, synthetism, diaphoresis, dispels the wind.”
Herba Equiseti Arvinsis: bitter in the mouth, cool, property is put down, nontoxic; Return lung, stomach, Liver Channel.Hemostasis, diuresis, improving eyesight.Main haematemesis, spitting of blood, has blood in stool, metrorrhagia, epistaxis, traumatic hemorrhage, conjunctivitis, gonorrhea." Shaanxi Chinese herbal medicine " carries: " clearing away heat and promoting diuresis, hemostasis, detumescence.Control urinary tract infection, difficulty and pain in micturition, fracture, epistaxis, spitting of blood, enterorrhagia, menorrhagia.”
Radix Ampelopsis Cantoniensis: acrid in the mouth, hardship, cool in nature; GUIXIN, spleen channel.Antiinflammatory, removing toxic substances.Control osteomyelitis, acute lymphadenitis, acute mastitis, impetigo, eczema, erysipelas, furuncle and phyma, halophilic bacteria alimentary toxicosis." register planted by Guangxi medicine " carries: " detumescence poison, clearing away summer-heat heat.”
Fructus Citri Limoniae: sour in the mouth is sweet, property is flat; Enter liver, stomach warp.Preventing phlegm from forming and stopping coughing, the spleen invigorating mainly treating bronchitis that promotes the production of body fluid, pertussis, vitamin C deficiency, heatstroke excessive thirst, inappetence, pregnant woman's disorder of stomach-QI, poor appetite, eructation etc.Modern medicine study confirms, Fructus Citri Limoniae has the effect eliminating cutaneous pigmentation, removes old dead cell and the dim heavy colour of skin is become clear, and improves the blood capillary of breaking.
Radix Merremiae hungaiensis: acrid in the mouth, slightly warm in nature; Return liver, gallbladder, large intestine channel.Removing toxic substances anthelmintic, synthetism, dissipating blood stasis for subsidence of swelling.Control traumatic injury, fracture, ascariasis, icterohepatitis.
Cortex Cinnamomi Burmannii: acrid in the mouth, micro-sweet, warm in nature; Return spleen channel.Warming middle-JIAO to relieve pain, expelling wind and cold, removing toxic substances and promoting subsidence of swelling, hemostasis.Cure mainly cold stomachache, stomachache is had loose bowels, inappetence, anemofrigid-damp arthralgia, lumbago and skelalgia, traumatic injury, wound hemorrhage, furuncle toxic swelling.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " expelling wind and cold, warming middle-JIAO to relieve pain.Control cold stomachache, abdominal distention, diarrhoea.”
Fructus rosae multiflorae: sour in the mouth, cool in nature; Return lung, spleen, liver, urinary bladder channel.Diuretic heat extraction, promoting blood circulation and detoxication.Cure mainly edema, beriberi, sore carbuncle, dysuria, abdominal pain in menstruation." modern Practical Chinese medicinal " carries: " except rheumatism.The dermatosiss such as edema, menoxenia, dysuria, beriberi generalized edema with distention of the chest and abdomen, syphilitic skin lesions incrustation, tinea skin ulcer are caused to generalized edema with distention of the chest and abdomen is breathed with cough, constipation and anuresis, person is effective with this for trusted subordinate's feeling of distension and oppression.”
Radix Oenotherae erythrosepalae: sweet in the mouth, hardship, warm in nature.Bone and muscle strengthening, expelling wind and removing dampness.Mainly curing rheumatism, bones and muscles pain.
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicinal granule of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of hard masses softening and resolving, removing toxic substances and promoting subsidence of swelling, blood circulation promoting and blood stasis dispelling, expelling wind and cold, there is significant curative effect, short treating period, instant effect to treatment erythema nodosum, safe and reliable, without any side effects, special effect is practical, wide popularization and application on clinic.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicinal granule effective ingredient of the present invention and weight are:
Treat a preparation method for the Chinese medicinal granule of erythema nodosum, comprise following processing step:
(1) Cortex Fraxini Malacophyllae Radicis, Enteromorpha clathrata (Roth) Grev. Emend bliding, Herba Gynurae bicoloris, Herba Polygoni cymosi, Rhizoma alcasiae odorae, Herba Cymbidii Penduli, Herba Equiseti Arvinsis, Radix Ampelopsis Cantoniensis, Radix Merremiae hungaiensis, Fructus rosae multiflorae and Radix Oenotherae erythrosepalae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Semen Ginkgo and Fructus Citri Limoniae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Herba Sarcandrae and Cortex Cinnamomi Burmannii are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Calami tetradactyli is cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4), juice, fine powder and filtrate mixing, make granule, obtain the Chinese medicinal granule for the treatment of erythema nodosum of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material composition of Chinese medicinal granule effective ingredient of the present invention and weight are:
The Chinese medicinal granule preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicinal granule effective ingredient of the present invention and weight are:
The Chinese medicinal granule preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicinal granule effective ingredient of the present invention and weight are:
The Chinese medicinal granule preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicinal granule effective ingredient of the present invention and weight are:
The Chinese medicinal granule preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicinal granule for the treatment of erythema nodosum, select the routine clinical observation of erythema nodosum patient 184 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 92 example, wherein male 46 example, women 46 example, 27 ~ 50 years old age, 38.5 years old mean age, average course of disease 1 year; Matched group 92 example, wherein male 46 example, women 46 example, 26 ~ 51 years old age, 38.5 years old mean age, average course of disease 1 year.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicinal granule of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 6 days, be 1 course for the treatment of, take 2 ~ 3 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group uses PIKANGWANG compound ketoconazole ointment, and after cleaning, get and evenly embrocate affected part in right amount, 2 times on the one, within 7 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover.
3, efficacy determination:
(1) cure: above-mentioned symptom all disappears, lab testing recovers normal
(2) effective: above-mentioned symptom obviously alleviates, lab testing obviously improves.
(3) effective: above-mentioned symptom alleviates to some extent, and lab testing takes a turn for the better to some extent.
(4) invalid: by treating rear above-mentioned symptom without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Yao, female, 29 years old, people from Shanghai Pudong New Area.Patient suffers from erythema nodosum, two lower limbs and shoulder arm pain, heavy when time is light, once used several drugs to treat, therapeutic effect is not fine, by taking Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of, two lower limbs and shoulder arm pain relief, after continuing to take 1 course for the treatment of, pain is lost entirely, and tuberosity all disappears.
2, Tan, man, 32 years old, Nanchuan of Chongqing people from district.Patient's tuberosity color is light red or secretly purple, meets cold increasing the weight of. normal recurrent exerbation, and companion face is pale, Shou Zuleng, light red tongue, deep,thready and forceless pulse, repeatedly treatment is all without positive effect, painful and life inconvenience is brought, through taking Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of to human body, red swelling of the skin, brothers symptom of feeling cold alleviates, and after continuing to take 1 course for the treatment of, skin nodules face is pale, Shou Zuleng, light red tongue, deep,thready and forceless pulse transference cure, after continuing to take 1 course for the treatment of, pars affecta skin recovers normal.
3, Liao, female, 37 years old, people from Fuxin, Liaoning.The erythema that patient skin suffers from almond large is raised, the red pain of color, aches with fever with chills, headache podomere, light red tongue, and white and thin fur is slightly greasy, floating and rapid pulse or slick and frivolous.Repeatedly go to see a doctor, all to no effect, cause stress and limbs misery, by taking Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of, symptom is clearly better, and after continuing to take 2 courses for the treatment of, symptom all disappears, and stress alleviates.
4, Zou, man, 40 years old, people from Cangzhou, Hebei.Patient two lower limb play red lesser tubercle half a year, local pain, edema of lower limbs, without cold and heat sense, frequent general joint pain, dizzy, headache, irritated in the heart, be diagnosed as erythema nodosum to hospital, take Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of, edeam of legs alleviation of pain is light, erythema is also shown in and goes down, and after taking 2 courses for the treatment of, swelling disappears, tuberosity all disappears, recovery from illness.
5, Xiong, female, 43 years old, Anqing people.Patient's back and the large erythema of skin of lumbar region almond raised, the red pain of color, aches with fever with chills, headache podomere, light red tongue, and white and thin fur is slightly greasy, floating and rapid pulse or slick and frivolous.Repeatedly utilize folk prescription or go to see a doctor, all to no effect, take Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of, skin skin bud treasure, redness, pain, podomere are ached and are alleviated, after taking 2 courses for the treatment of, back and large erythema, the pain of skin of lumbar region almond, heating podomere is ached transference cure, and after taking 3 courses for the treatment of, pars affecta skin recovers normal.
6, gold certain, man, 46 years old, Zhoushan Of Zhejiang Province people.Patient two lower limb, shoulder arthralgia pain, pain is stride difficulty then, and two medial legs occur that little lump is several in recent years, aubergine, invalid by rheumatism treatment, take Chinese medicinal granule of the present invention treatment, after taking 1 course for the treatment of, local aubergine tuberosity disappears gradually, shoulder pain does not show, after continuing to take 1 course for the treatment of, tuberosity disappears completely, recovery from illness.
Claims (5)
1. treat a Chinese medicinal granule for erythema nodosum, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Cortex Fraxini Malacophyllae Radicis 67 ~ 91 parts of Enteromorpha clathrata (Roth) Grev. Emend bliding 65 ~ 89 parts of Herba Gynurae bicoloris 64 ~ 88 portions of Semen Ginkgoes 64 ~ 88 parts
Herba Polygoni cymosi 63 ~ 87 portions of Rhizoma alcasiae odoraes 62 ~ 86 parts of Herba Cymbidii Penduli 62 ~ 86 parts of Herba Sarcandraes 61 ~ 85 parts
58 ~ 82 parts, Herba Calami tetradactyli 61 ~ 85 portions of Herba Equiseti Arvinsiss 59 ~ 83 parts of Radix Ampelopsis Cantoniensiss 58 ~ 82 portions of Fructus Citri Limoniaes
Radix Merremiae hungaiensis 56 ~ 80 parts of Cortex Cinnamomi Burmanniis 55 ~ 79 parts of Fructus rosae multiflorae 52 ~ 76 parts of Radix Oenotherae erythrosepalaes 47 ~ 71 parts.
2. a kind of Chinese medicinal granule for the treatment of erythema nodosum according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Cortex Fraxini Malacophyllae Radicis 71 ~ 87 parts of Enteromorpha clathrata (Roth) Grev. Emend bliding 69 ~ 85 parts of Herba Gynurae bicoloris 68 ~ 84 portions of Semen Ginkgoes 68 ~ 84 parts
Herba Polygoni cymosi 70 ~ 83 portions of Rhizoma alcasiae odoraes 66 ~ 82 parts of Herba Cymbidii Penduli 66 ~ 82 parts of Herba Sarcandraes 65 ~ 81 parts
62 ~ 78 parts, Herba Calami tetradactyli 65 ~ 81 portions of Herba Equiseti Arvinsiss 63 ~ 79 parts of Radix Ampelopsis Cantoniensiss 62 ~ 78 portions of Fructus Citri Limoniaes
Radix Merremiae hungaiensis 60 ~ 76 parts of Cortex Cinnamomi Burmanniis 59 ~ 75 parts of Fructus rosae multiflorae 56 ~ 72 parts of Radix Oenotherae erythrosepalaes 51 ~ 67 parts.
3. a kind of Chinese medicinal granule for the treatment of erythema nodosum according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Cortex Fraxini Malacophyllae Radicis 75 ~ 83 parts of Enteromorpha clathrata (Roth) Grev. Emend bliding 73 ~ 81 parts of Herba Gynurae bicoloris 72 ~ 80 portions of Semen Ginkgoes 72 ~ 80 parts
Herba Polygoni cymosi 71 ~ 79 portions of Rhizoma alcasiae odoraes 70 ~ 78 parts of Herba Cymbidii Penduli 70 ~ 78 parts of Herba Sarcandraes 69 ~ 77 parts
66 ~ 74 parts, Herba Calami tetradactyli 69 ~ 77 portions of Herba Equiseti Arvinsiss 67 ~ 75 parts of Radix Ampelopsis Cantoniensiss 65 ~ 74 portions of Fructus Citri Limoniaes
Radix Merremiae hungaiensis 64 ~ 72 parts of Cortex Cinnamomi Burmanniis 63 ~ 71 parts of Fructus rosae multiflorae 60 ~ 68 parts of Radix Oenotherae erythrosepalaes 55 ~ 63 parts.
4. a kind of Chinese medicinal granule for the treatment of erythema nodosum according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicinal granule effective ingredient are:
Cortex Fraxini Malacophyllae Radicis 79 parts of Enteromorpha clathrata (Roth) Grev. Emend bliding 77 parts of Herba Gynurae bicoloris 76 portions of Semen Ginkgoes 76 parts
Herba Polygoni cymosi 75 portions of Rhizoma alcasiae odoraes 74 parts of Herba Cymbidii Penduli 74 parts of Herba Sarcandraes 73 parts
70 parts, Herba Calami tetradactyli 73 portions of Herba Equiseti Arvinsiss 71 parts of Radix Ampelopsis Cantoniensiss 71 portions of Fructus Citri Limoniaes
Radix Merremiae hungaiensis 68 parts of Cortex Cinnamomi Burmanniis 67 parts of Fructus rosae multiflorae 64 parts of Radix Oenotherae erythrosepalaes 59 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicinal granule of erythema nodosum, it is characterized in that: comprise following processing step:
(1) Cortex Fraxini Malacophyllae Radicis, Enteromorpha clathrata (Roth) Grev. Emend bliding, Herba Gynurae bicoloris, Herba Polygoni cymosi, Rhizoma alcasiae odorae, Herba Cymbidii Penduli, Herba Equiseti Arvinsis, Radix Ampelopsis Cantoniensis, Radix Merremiae hungaiensis, Fructus rosae multiflorae and Radix Oenotherae erythrosepalae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Semen Ginkgo and Fructus Citri Limoniae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) Herba Sarcandrae and Cortex Cinnamomi Burmannii are put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(4) Herba Calami tetradactyli is cleaned, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaim ethanol, filter, obtain filtrate for subsequent use;
(5) by the thick paste obtained by above-mentioned steps (1) ~ (4), juice, fine powder and filtrate mixing, make granule, obtain the Chinese medicinal granule of described treatment erythema nodosum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410796927.0A CN104524207A (en) | 2014-12-19 | 2014-12-19 | Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410796927.0A CN104524207A (en) | 2014-12-19 | 2014-12-19 | Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104524207A true CN104524207A (en) | 2015-04-22 |
Family
ID=52839963
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410796927.0A Pending CN104524207A (en) | 2014-12-19 | 2014-12-19 | Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104524207A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105477476A (en) * | 2016-01-22 | 2016-04-13 | 李先强 | Erythema nodosum treatment medicine |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405692A (en) * | 2013-06-06 | 2013-11-27 | 马建国 | Unguent for treating erythema nodosum and preparation method thereof |
| CN103432432A (en) * | 2013-08-01 | 2013-12-11 | 马雨婷 | Traditional Chinese medicine composition for treating erythema nodosum |
| CN103735914A (en) * | 2014-01-24 | 2014-04-23 | 梁英 | Ointment for preventing and treating chilblain and preparation method thereof |
-
2014
- 2014-12-19 CN CN201410796927.0A patent/CN104524207A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103405692A (en) * | 2013-06-06 | 2013-11-27 | 马建国 | Unguent for treating erythema nodosum and preparation method thereof |
| CN103432432A (en) * | 2013-08-01 | 2013-12-11 | 马雨婷 | Traditional Chinese medicine composition for treating erythema nodosum |
| CN103735914A (en) * | 2014-01-24 | 2014-04-23 | 梁英 | Ointment for preventing and treating chilblain and preparation method thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105477476A (en) * | 2016-01-22 | 2016-04-13 | 李先强 | Erythema nodosum treatment medicine |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103463500B (en) | Medicament for treating cerebral hemorrhage | |
| CN104258151A (en) | Drug for treating nephropyelitis and preparation method thereof | |
| CN104383053B (en) | Traditional Chinese medicine preparation for treating urinary tract infection and production method of traditional Chinese medicine preparation | |
| CN103536881A (en) | Drug for treating chronic gastritis | |
| CN104398733B (en) | A kind of Chinese medicine preparation for treating caused by hepatic stagnation qi stagnation thyroid cancer | |
| CN105106771A (en) | Medicine for recovery of puerperae subjected to caesarean birth operations and preparation method of medicine | |
| CN103920046A (en) | Medicine for treating cystitis and preparation method thereof | |
| CN103446400B (en) | Traditional Chinese medicine preparation for treating asthma | |
| CN104524207A (en) | Traditional Chinese medicine particles for treating erythema nodosum and preparation method of traditional Chinese medicine particles | |
| CN104352667A (en) | Medicine for treating nonspecific vaginitis and preparation method | |
| CN104147277A (en) | Traditional Chinese medicinal preparation for treating myasthenia gravis and preparation method | |
| CN104547384A (en) | Oral liquid for treating paraquat poisoning and preparation method of oral liquid | |
| CN103893415A (en) | Medicine for treating irregular menstruation and preparation method thereof | |
| CN104623217A (en) | Traditional Chinese medicine preparation for treating asthma and preparation method thereof | |
| CN103463463A (en) | Traditional Chinese medicine preparation for replenishing and activating blood and dispelling wind and removing dampness | |
| CN103893491B (en) | A kind of medicine and preparation method for the treatment of cyclomastopathy | |
| CN103877557B (en) | A kind of Chinese medicine ointment and preparation method for the treatment of tinea unguium | |
| CN103751624B (en) | A kind of medicine and preparation method for the treatment of numb limbs and tense tendons after apoplexy | |
| CN104666911A (en) | Medicine for treating urticaria and preparation method thereof | |
| CN105560753A (en) | Medicine for curing scapulohumeral periarthritis and preparing method | |
| CN104547450A (en) | Traditional Chinese medicine preparation for treating hyperplasia of mammary glands and preparation method thereof | |
| CN104666469A (en) | Traditional Chinese medicine composition for treating phase III shoulder-hand syndrome | |
| CN105288195A (en) | Medicine for treating thyroiditis and preparation method for medicine | |
| CN105147941A (en) | Yin-nourishing kidney-reinforcing traditional Chinese medicine composition as well preparation thereof and preparation method of preparation | |
| CN104435862A (en) | Traditional Chinese medicinal ointment for treating neurodermatitis and preparation method of traditional Chinese medicinal ointment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150422 |