CN102727567A - Chinese medicine composition with radiation protecting function - Google Patents
Chinese medicine composition with radiation protecting function Download PDFInfo
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- CN102727567A CN102727567A CN2012100440426A CN201210044042A CN102727567A CN 102727567 A CN102727567 A CN 102727567A CN 2012100440426 A CN2012100440426 A CN 2012100440426A CN 201210044042 A CN201210044042 A CN 201210044042A CN 102727567 A CN102727567 A CN 102727567A
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Abstract
The invention relates to a Chinese medicine composition with radiation protecting function and a preparation method thereof. The Chinese medicine composition comprises the following ingredients: 5-30 weight parts of coffee senna seed, 5-30 weight parts of Goldfussia pentstemonoides, 5-30 weight parts of Radix Adenophorae, and 5-30 weight parts of Chinese honey locust. According to the invention, under the guidance of traditional Chinese medicine theories, by reasonable proportioning and synergism of the ingredients, the radiation protecting function is achieved.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Chinese medicine composition with radiation protection.
Technical background
All objects of occurring in nature, as long as temperature is at absolute temperature above zero, all with the ceaselessly outside constantly transfer of heat of form of electromagnetic wave, this energy-delivering mode is called radiation; Local work study in the radiation source set of circumstances can cause various malaise symptoms, such as insomnia, hypomnesis, body void, hypoimmunity etc.
Social development causes various radioactivity factors constantly to increase, and radiation at present has been penetrated into the social life every field, and in daily life, mobile phone, computer progressively are human lives and work necessary.In medical range, radiodiagnosis progressively increases with treatment, such as radiation x-ray, CT diagnosis etc.; Radiotherapy has become one of three big means of treatment malignant tumor; But above-mentioned radiotherapy brings curative effect simultaneously to the patient, causes damage in various degree also for patient and medical personnel, and medical personnel often are directly exposed under the radiation especially sometimes; Radiation protection is difficulty further, and radiation damage also aggravates.Nuclear energy is applied in China progressively to be accelerated, the foundation of large quantities of nuclear power stations, and nuclear power cargo ship or the like, contact the radiation worker increase gradually, and large quantities of practitioners also needs feasible health protection.
Chinese invention patent publication number CN101607059 discloses " application of a kind of Chinese medicine composition in the medicine of preparation treatment and prevention radiation injury ", and it is made up of the Radix Astragali, Fructus Ligustri Lucidi, Radix Ginseng, Ganoderma, Rhizoma Curcumae, Herb Gynostemmae Pentaphylli, the Rhizoma Atractylodis Macrocephalae, Poria, Cordyceps, Radix Cynanchi Paniculati, Eupolyphaga Seu Steleophaga, Radix Notoginseng, Herba Hedyotidis Diffusae, Herba Scutellariae Barbatae, Massa Medicata Fermentata preparata; Chinese invention patent publication number CN101361811 discloses " a kind of radiation-resistant Chinese medicine composition and preparation method thereof "; Chinese invention patent publication number CN101822772A discloses " application of Bulbus Allii Macrostemonis in preparation radiation protection health products or medicine ".From disclosed patent documentation, being the Chinese medicine composition that raw material embodies radiation resistance with Chinese medicine at present, is main constitutive material to improve the immunity medical material mostly, knows compatibility down in theory of Chinese medical science, embodies the QI invigorating effect.
Summary of the invention
The object of the invention provides a kind of radiation-resistant Chinese medicine composition, and under Chinese medical theory instructed, the rational proportion through each Chinese crude drug played synergism, plays radiation resistance.
For realizing above-mentioned purpose, the technical scheme that the present invention adopts is: a kind of Chinese medicine composition with radiation protection is processed by following bulk drugs: Semen Cassiae Occidemtalis 5-30 part, warm Folium Isatidis 5-30 part, Radix Adenophorae 5-30 part, Fructus Gleditsia 5-30 part.
The traditional Chinese medicinal composition raw materials weight portion that preferably has radiation protection consists of: 15 parts of Semen Cassiae Occidemtalis, 9 parts of warm Folium Isatidis, 15 parts of Radix Adenophoraes, 9 parts in Fructus Gleditsia.
In the Chinese medicine composition of radiation protection of the present invention: Semen Cassiae Occidemtalis, sweet in the mouth, hardship, cool in nature, have the removing liver heat and toxic substances effect; The temperature Folium Isatidis, bitter, hot, cold nature has heat-clearing and toxic substances removing removing heat from blood effect; Fructus Gleditsia, warm in nature, have the damp eliminating detoxicating functions; Radix Adenophorae, sweet in the mouth, cold nature has supplementing QI and nourishing YIN lung heat clearing effect.The appropriate compatibility of above-mentioned medical material plays heat-clearing toxin-expelling functions; This radioprotective Chinese medicine composition is not seen bibliographical information.
The present invention is the Chinese medicine composition that screening obtains having clear and definite radiation protection from Chinese crude drug, through improving the leucocytes reduction and removing interior free yl of radiation to body damage, reaches the effect of control radiation damage; Be suitable for long-term work and take for a long time, also be suitable for tumor radiotherapy front and back patient the radiation environment crowd.
The specific embodiment
Embodiment 1 has the Chinese medicine composition of radiation protection
(1) the raw material medicines in portions by weight proportioning is following:
Semen Cassiae Occidemtalis 50 grams, warm Folium Isatidis 50 grams, Radix Adenophorae 50 grams, Fructus Gleditsia 50 grams.
(2) method for preparing is following:
1. get crude drug by above-mentioned weight portion proportioning;
2. add 8 times of water gagings of above-mentioned medical material gross weight and soaked 2 hours, heating decocts, and after-filtration boils; Medicinal residues add 8 times of water gagings again and are heated to and boil, the after-filtration that boils, and filtrating merges, and is water decoction.
Embodiment 2 has the Chinese medicine composition of radiation protection
(1) the raw material medicines in portions by weight proportioning is following:
Semen Cassiae Occidemtalis 300 grams, warm Folium Isatidis 300 grams, Radix Adenophorae 300 grams, Fructus Gleditsia 300 grams.
(2) method for preparing is following:
1. get crude drug by above-mentioned weight portion proportioning;
2. add 8 times of water gagings of above-mentioned medical material gross weight and soaked 2 hours, heating decocts, and after-filtration boils; Medicinal residues add 8 times of water gagings again and are heated to and boil, the after-filtration that boils, and filtrating merges, and is water decoction.
Embodiment 3 has the Chinese medicine composition of radiation protection
(1) the raw material medicines in portions by weight proportioning is following:
Semen Cassiae Occidemtalis 150 grams, warm Folium Isatidis 90 grams, Radix Adenophorae 150 grams, Fructus Gleditsia 90 grams.
(2) method for preparing is following:
1. get crude drug by above-mentioned weight portion proportioning;
2. add 8 times of water gagings of above-mentioned medical material gross weight and soaked 2 hours, heating decocts, and after-filtration boils; Medicinal residues add 8 times of water gagings again and are heated to and boil, the after-filtration that boils, and filtrating merges, and is water decoction.
Experimental example 1 Chinese medicine composition of the present invention influences radiation damage mice peripheral white blood cell
1.1 experimental technique
50 of cleaning level NIH kind mices are divided into 5 groups: blank control group, model group, the high, medium and low dose groups of Chinese medicine composition, 10 every group at random.Except that blank control group, all the other group mices are all used
60The Co ray carries out a subtotal body irradiation, and the irradiation total absorbed dose is 2.0Gy.Chinese medicine composition of the present invention respectively organize mice in
60The previous day is irritated the aqueous extract that stomach gives corresponding dosage in the Co radiation, and each is organized dosage and is respectively: low dose group 5g/kg, middle dose groups 10g/kg, high dose group 20g/kg; Matched group and model group animal are irritated stomach and give isodose normal saline, and each organizes administration and normal saline is irritated stomach once every day, continuous 7 days.Each treated animal is adopted tail tip blood the 7th day twice respectively at pre-irradiation, irradiation back, surveys leukocyte count.
1.2 experimental result
The traditional Chinese medicine composition water extract sees the following form 1 to the result that influences of radiation damage mice peripheral white blood cell.
Table 1 traditional Chinese medicine composition water extract is to the influence of radiation damage mice peripheral white blood cell
* model group and blank control group compare P<0.01; * and model control group be P<0.01 relatively
Each organizes comparison model group and blank control group comparison between the leukocyte count before the mice radiation, there was no significant difference P>0.05;
60Respectively organized the murine interleukin number in 7 days behind the Co x radiation x and obviously reduce, this experiment modeling success is described.The murine interleukin counting all has rising in various degree after each dose groups medication of Chinese medicine composition of the present invention, have highly significant property meaning (P<0.01) with the model group comparing difference, and each dose groups has dose-effect relationship.
Through the explanation of above-mentioned experimental result, Chinese medicine composition of the present invention has and improves the effect that mice PBL that radiation damage causes reduces.
Claims (3)
1. the Chinese medicine composition with radiation protection is characterized in that being processed by following raw material medicaments in part by weight proportioning: Semen Cassiae Occidemtalis 5-30 part, warm Folium Isatidis 5-30 part, Radix Adenophorae 5-30 part, Fructus Gleditsia 5-30 part.
2. Chinese medicine composition according to claim 1 is characterized in that this Chinese medicine composition is to be processed by following bulk drugs: 15 parts of Semen Cassiae Occidemtalis, 9 parts of warm Folium Isatidis, 15 parts of Radix Adenophoraes, 9 parts in Fructus Gleditsia.
3. Chinese medicine composition according to claim 1 and 2 can prepare conventional oral formulations.
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CN201210044042.6A CN102727567B (en) | 2012-02-24 | 2012-02-24 | Chinese medicine composition with radiation protecting function |
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CN201210044042.6A CN102727567B (en) | 2012-02-24 | 2012-02-24 | Chinese medicine composition with radiation protecting function |
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CN102727567A true CN102727567A (en) | 2012-10-17 |
CN102727567B CN102727567B (en) | 2014-10-01 |
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Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1709375A (en) * | 2005-06-27 | 2005-12-21 | 广州康采恩医药有限公司 | Chewing gum for radiation protection |
CN101607059A (en) * | 2008-06-20 | 2009-12-23 | 河北以岭医药研究院有限公司 | The application of a kind of Chinese medicine composition in the medicine of preparation treatment and prevention radiation injury |
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2012
- 2012-02-24 CN CN201210044042.6A patent/CN102727567B/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1709375A (en) * | 2005-06-27 | 2005-12-21 | 广州康采恩医药有限公司 | Chewing gum for radiation protection |
CN101607059A (en) * | 2008-06-20 | 2009-12-23 | 河北以岭医药研究院有限公司 | The application of a kind of Chinese medicine composition in the medicine of preparation treatment and prevention radiation injury |
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