CN102712607B - 作为具有治疗效用的受体调节剂的化合物 - Google Patents
作为具有治疗效用的受体调节剂的化合物 Download PDFInfo
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- CN102712607B CN102712607B CN201080062159.6A CN201080062159A CN102712607B CN 102712607 B CN102712607 B CN 102712607B CN 201080062159 A CN201080062159 A CN 201080062159A CN 102712607 B CN102712607 B CN 102712607B
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- alkyl
- thienyl
- amino
- propyl
- phosphonic acid
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- 0 CCC1=C(*)C(*)=C(C)C(*C)*1 Chemical compound CCC1=C(*)C(*)=C(C)C(*C)*1 0.000 description 2
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| CA2833313A1 (en) * | 2011-04-14 | 2012-10-18 | Allergan, Inc. | Phenyl bicyclic methyl amine derivatives as sphingosine-1 phosphate receptors modulators |
| AU2013222574A1 (en) | 2012-02-21 | 2014-09-18 | Allergan, Inc. | Phenoxy-azetidine derivatives as sphingosine 1-phosphate (S1P) receptor modulators |
| WO2014093253A1 (en) * | 2012-12-13 | 2014-06-19 | Allergan, Inc. | Novel aromatic thio compounds as receptor modulators |
| US9540362B2 (en) | 2013-02-20 | 2017-01-10 | Lg Life Sciences Ltd. | Sphingosine-1-phosphate receptor agonists, methods of preparing the same, and pharmaceutical compositions containing the same as an active agent |
| WO2014138075A1 (en) * | 2013-03-07 | 2014-09-12 | Allergan, Inc. | Phosphonic acid compounds as sphingosine-1-phosphate receptor modulators |
| US20150045328A1 (en) * | 2013-08-08 | 2015-02-12 | Allergan, Inc. | Disubstituted aryl oxy derivatives as sphingosine-1 phosphate receptors modulators |
| WO2015021109A1 (en) * | 2013-08-08 | 2015-02-12 | Allergan, Inc. | Disubstituted aryl azetidine derivatives as sphingosine-1-phosphate receptors modulators |
| WO2015073547A1 (en) * | 2013-11-13 | 2015-05-21 | Allergan, Inc. | Disubstituted phenoxy azetidine derivatives as sphingosine-1-phosphate (s1p) receptor modulators |
| BR112020015567A2 (pt) | 2018-02-02 | 2021-02-02 | Kyoto University | medicamento para prevenir ou tratar doença oftálmica associada com neovascularização intraocular e/ou permeabilidade vascular intraocular realçadas |
| CN117136183A (zh) * | 2021-04-14 | 2023-11-28 | 株式会社Lg化学 | 制备鞘氨醇-1-磷酸酯受体激动剂的新方法 |
| CN117242057A (zh) * | 2021-04-14 | 2023-12-15 | 株式会社Lg化学 | 制备用于合成鞘氨醇-1-磷酸酯受体激动剂的中间体的方法 |
| KR102802371B1 (ko) * | 2021-04-14 | 2025-05-07 | 주식회사 엘지화학 | 스핑고신-1-인산 수용체 효능제의 신규한 제조방법 |
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| US6235912B1 (en) * | 1997-03-12 | 2001-05-22 | Takara Shuzo Co., Ltd. | Sphingosine analogues |
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| DE10010067A1 (de) * | 2000-03-02 | 2001-09-06 | Bayer Ag | Neue Imidazotriazinone und ihre Verwendung |
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| AU2003216054B2 (en) * | 2002-01-18 | 2007-01-04 | Merck & Co., Inc. | Selective S1P1/Edg1 receptor agonists |
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| TW200827346A (en) * | 2006-11-03 | 2008-07-01 | Astrazeneca Ab | Chemical compounds |
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