CN102711467A - 吡啶并[3,4-b]吲哚类及使用方法 - Google Patents

吡啶并[3,4-b]吲哚类及使用方法 Download PDF

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Publication number
CN102711467A
CN102711467A CN2010800528027A CN201080052802A CN102711467A CN 102711467 A CN102711467 A CN 102711467A CN 2010800528027 A CN2010800528027 A CN 2010800528027A CN 201080052802 A CN201080052802 A CN 201080052802A CN 102711467 A CN102711467 A CN 102711467A
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China
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substituted
unsubstituted
alkyl
formula
halogen
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CN2010800528027A
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Chinese (zh)
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R·P·贾殷
S·查克拉瓦蒂
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Medivation Technologies LLC
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Medivation Technologies LLC
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Publication of CN102711467A publication Critical patent/CN102711467A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CN2010800528027A 2009-09-23 2010-09-23 吡啶并[3,4-b]吲哚类及使用方法 Pending CN102711467A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24514809P 2009-09-23 2009-09-23
US61/245,148 2009-09-23
PCT/US2010/050079 WO2011038162A1 (en) 2009-09-23 2010-09-23 Pyrido(3,4-b)indoles and methods of use

Publications (1)

Publication Number Publication Date
CN102711467A true CN102711467A (zh) 2012-10-03

Family

ID=43796210

Family Applications (1)

Application Number Title Priority Date Filing Date
CN2010800528027A Pending CN102711467A (zh) 2009-09-23 2010-09-23 吡啶并[3,4-b]吲哚类及使用方法

Country Status (8)

Country Link
US (2) US20130137705A1 (https=)
EP (1) EP2480079A4 (https=)
JP (1) JP5791611B2 (https=)
CN (1) CN102711467A (https=)
AU (1) AU2010298167B2 (https=)
BR (1) BR112012006644A2 (https=)
CA (1) CA2775129A1 (https=)
WO (1) WO2011038162A1 (https=)

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CN104839184A (zh) * 2015-04-18 2015-08-19 广东中迅农科股份有限公司 含有氯吡嘧磺隆和氯氨吡啶酸以及烟嘧磺隆的农药组合物

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RU2544856C2 (ru) 2008-01-25 2015-03-20 Сергей Олегович Бачурин НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
TWI443098B (zh) 2008-03-24 2014-07-01 Medivation Technologies Inc 吡啶并〔３，４－ｂ〕吲哚及使用方法
CN102046625B (zh) 2008-03-24 2015-04-08 梅迪维新技术公司 桥连杂环化合物及其使用方法
AU2009308706C1 (en) 2008-10-31 2016-01-21 Medivation Technologies, Inc. Pyrido (4,3-b) indoles containing rigid moieties
WO2010051503A1 (en) 2008-10-31 2010-05-06 Medivation Technologies, Inc. Azepino [4, 5-b] indoles and methods of use
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
EP2385829B1 (en) 2009-01-09 2018-08-01 Board of Regents of the University of Texas System Pro-neurogenic compounds
US9095572B2 (en) 2009-01-09 2015-08-04 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9962368B2 (en) 2009-01-09 2018-05-08 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
JP5827943B2 (ja) 2009-04-29 2015-12-02 メディベイション テクノロジーズ， インコーポレイテッド ピリド［４，３−ｂ］インドールおよびその使用方法
CA2760541A1 (en) 2009-04-29 2010-11-04 Medivation Technologies, Inc. Pyrido[4,3-b] indoles and methods of use
AU2010298169B2 (en) 2009-09-23 2015-10-29 Medivation Technologies, Inc. Bridged heterocyclic compounds and methods of use
WO2011038163A1 (en) 2009-09-23 2011-03-31 Medivation Technologies, Inc. Pyrido[3,4-b]indoles and methods of use
EP2480078A4 (en) 2009-09-23 2013-03-06 Medivation Technologies Inc PYRIDO- [4,3-B] INDOLE AND USE METHOD THEREFOR
US9034865B2 (en) 2010-02-18 2015-05-19 Medivation Technologies, Inc. Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
US9193728B2 (en) 2010-02-18 2015-11-24 Medivation Technologies, Inc. Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
WO2011103485A1 (en) 2010-02-18 2011-08-25 Medivation Technologies, Inc. Fused tetracyclic pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
WO2011103430A1 (en) 2010-02-19 2011-08-25 Medivation Technologies, Inc. Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
CN103476417A (zh) 2011-02-18 2013-12-25 梅迪维新技术公司 治疗糖尿病的化合物和方法
US9434747B2 (en) 2011-02-18 2016-09-06 Medivation Technologies, Inc. Methods of treating diabetes
US9035056B2 (en) 2011-02-18 2015-05-19 Medivation Technologies, Inc. Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use
US20140155384A1 (en) 2011-02-18 2014-06-05 Medivation Technologies, Inc. Compounds and methods of treating diabetes
AU2013305591B2 (en) 2012-08-24 2017-04-13 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
WO2015070234A2 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective compounds and use thereof
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US11458129B2 (en) * 2017-11-02 2022-10-04 California Institute Of Technology Neurokinin antagonists and uses thereof
EP3703716B1 (en) 2017-11-02 2026-03-25 California Institute of Technology Expression of neuropeptides
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof

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WO1996034865A1 (en) * 1995-05-05 1996-11-07 Novo Nordisk A/S Novel heterocyclic chemistry
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WO2008123796A2 (ru) * 2007-04-05 2008-10-16 Alla Chem, Llc Замещенные 2,3,4,5-tetpaгидpo-1h-пиpидo[4,3-b]иhдoлы, способ их получения и применения
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Publication number Priority date Publication date Assignee Title
GB721171A (en) * 1951-04-30 1954-12-29 Bayer Ag Derivatives of ª‰- and ª†- carbolines
CN1148340A (zh) * 1994-03-11 1997-04-23 伊莱利利公司 治疗与5htzb受体有关病症的方法
WO1996034865A1 (en) * 1995-05-05 1996-11-07 Novo Nordisk A/S Novel heterocyclic chemistry
WO1999025340A1 (en) * 1997-11-14 1999-05-27 Eli Lilly And Company Treatment for alzheimer's disease
CN1282743A (zh) * 1999-07-23 2001-02-07 阿迪尔公司 新颖的β－咔啉化合物、它们的制备方法和含有它们的药物组合物
WO2008123796A2 (ru) * 2007-04-05 2008-10-16 Alla Chem, Llc Замещенные 2,3,4,5-tetpaгидpo-1h-пиpидo[4,3-b]иhдoлы, способ их получения и применения
WO2009120717A2 (en) * 2008-03-24 2009-10-01 Medivation Technologies, Inc. Pyrido [3, 4-b] indoles and methods of use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104839184A (zh) * 2015-04-18 2015-08-19 广东中迅农科股份有限公司 含有氯吡嘧磺隆和氯氨吡啶酸以及烟嘧磺隆的农药组合物

Also Published As

Publication number Publication date
WO2011038162A1 (en) 2011-03-31
BR112012006644A2 (pt) 2019-09-24
CA2775129A1 (en) 2011-03-31
JP2013505946A (ja) 2013-02-21
US20130123277A1 (en) 2013-05-16
JP5791611B2 (ja) 2015-10-07
AU2010298167A1 (en) 2012-04-12
EP2480079A1 (en) 2012-08-01
EP2480079A4 (en) 2015-04-08
AU2010298167B2 (en) 2015-12-24
US20130137705A1 (en) 2013-05-30

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